-
1
-
-
27744519400
-
Fuel feeds function: Energy metabolism and the T-cell response
-
Fox CJ, Hammerman PS, Thompson CB Fuel feeds function: energy metabolism and the T-cell response. Nat Rev Immunol 2005 ; 5: 844-852.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 844-852
-
-
Fox, C.J.1
Hammerman, P.S.2
Thompson, C.B.3
-
2
-
-
0347505003
-
CD28-mediated co-stimulation: A quantitative support for TCR signalling
-
Acuto O., Michel F. CD28-mediated co-stimulation: a quantitative support for TCR signalling. Nat Rev Immunol 2003 ; 3: 939-951.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 939-951
-
-
Acuto, O.1
Michel, F.2
-
3
-
-
0024502876
-
Glucose, glutamine and ketone body utilisation by resting and concanavalin A activated rat splenic lymphocytes
-
Og'Rourke AM, Rider CC Glucose, glutamine and ketone body utilisation by resting and concanavalin A activated rat splenic lymphocytes. Biochim Biophys Acta 1989 ; 1010: 342-345.
-
(1989)
Biochim Biophys Acta
, vol.1010
, pp. 342-345
-
-
Og'Rourke, A.M.1
Rider, C.C.2
-
4
-
-
0027511220
-
The role of the Crabtree effect and an endogenous fuel in the energy metabolism of resting and proliferating thymocytes
-
Guppy M., Greiner E., Brand K. The role of the Crabtree effect and an endogenous fuel in the energy metabolism of resting and proliferating thymocytes. Eur J Biochem 1993 ; 212: 95-99.
-
(1993)
Eur J Biochem
, vol.212
, pp. 95-99
-
-
Guppy, M.1
Greiner, E.2
Brand, K.3
-
5
-
-
0015924743
-
Changes in the carbohydrate metabolism of mitogenically stimulated human peripheral lymphocytes. II. Relative importance of glycolysis and oxidative phosphorylation on phytohaemagglutinin stimulation
-
Roos D., Loos JA Changes in the carbohydrate metabolism of mitogenically stimulated human peripheral lymphocytes. II. Relative importance of glycolysis and oxidative phosphorylation on phytohaemagglutinin stimulation. Exp Cell Res 1973 ; 77: 127-135.
-
(1973)
Exp Cell Res
, vol.77
, pp. 127-135
-
-
Roos, D.1
Loos, J.A.2
-
6
-
-
34548030192
-
The proapoptotic factors Bax and Bak regulate T cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis
-
Jones RG, Bui T., White C., et al. The proapoptotic factors Bax and Bak regulate T cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis. Immunity 2007 ; 27: 268-280.
-
(2007)
Immunity
, vol.27
, pp. 268-280
-
-
Jones, R.G.1
Bui, T.2
White, C.3
-
7
-
-
0021084821
-
Mechanism of activation of pyruvate dehydrogenase by mitogens in pig lymphocytes
-
Baumgarten E., Brand MD, Pozzan T. Mechanism of activation of pyruvate dehydrogenase by mitogens in pig lymphocytes. Biochem J 1983 ; 216: 359-367.
-
(1983)
Biochem J
, vol.216
, pp. 359-367
-
-
Baumgarten, E.1
Brand, M.D.2
Pozzan, T.3
-
8
-
-
0036069699
-
The CD28 signaling pathway regulates glucose metabolism
-
Frauwirth KA, Riley JL, Harris MH, et al. The CD28 signaling pathway regulates glucose metabolism. Immunity 2002 ; 16: 769-777.
-
(2002)
Immunity
, vol.16
, pp. 769-777
-
-
Frauwirth, K.A.1
Riley, J.L.2
Harris, M.H.3
-
9
-
-
57049132739
-
Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c
-
Vaughn AE, Deshmukh M. Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c. Nat Cell Biol 2008 ; 10: 1477-1483.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 1477-1483
-
-
Vaughn, A.E.1
Deshmukh, M.2
-
10
-
-
0030945198
-
Aerobic glycolysis by proliferating cells: A protective strategy against reactive oxygen species
-
Brand KA, Hermfisse U. Aerobic glycolysis by proliferating cells: a protective strategy against reactive oxygen species. FASEB J 1997 ; 11: 388-395.
-
(1997)
FASEB J
, vol.11
, pp. 388-395
-
-
Brand, K.A.1
Hermfisse, U.2
-
11
-
-
66249108601
-
Understanding the Warburg effect: The metabolic requirements of cell proliferation
-
Vander Heiden MG, Cantley LC, Thompson CB Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 2009 ; 324: 1029-1033.
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
12
-
-
40049093765
-
Systemic lupus erythematosus
-
Rahman A., Isenberg DA Systemic lupus erythematosus. N Engl J Med 2008 ; 358: 929-939.
-
(2008)
N Engl J Med
, vol.358
, pp. 929-939
-
-
Rahman, A.1
Isenberg, D.A.2
-
13
-
-
0035923519
-
Selective blockade of T lymphocyte K(+) channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis
-
Beeton C., Wulff H., Barbaria J., et al. Selective blockade of T lymphocyte K(+) channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis. Proc Natl Acad Sci U S A 2001 ; 98: 13942-13947.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 13942-13947
-
-
Beeton, C.1
Wulff, H.2
Barbaria, J.3
-
14
-
-
33749622448
-
Monocyte-derived dendritic cells over-express CD86 in patients with systemic lupus erythematosus
-
Oxford )
-
Decker P., Kotter I., Klein R., Berner B., Rammensee HG Monocyte-derived dendritic cells over-express CD86 in patients with systemic lupus erythematosus. Rheumatology (Oxford) 2006 ; 45: 1087-1095.
-
(2006)
Rheumatology
, vol.45
, pp. 1087-1095
-
-
Decker, P.1
Kotter, I.2
Klein, R.3
Berner, B.4
Rammensee, H.G.5
-
15
-
-
17644434779
-
Analysis of CD80 and CD86 expression on peripheral blood B lymphocytes reveals increased expression of CD86 in lupus patients
-
Folzenlogen D., Hofer MF, Leung DY, Freed JH, Newell MK Analysis of CD80 and CD86 expression on peripheral blood B lymphocytes reveals increased expression of CD86 in lupus patients. Clin Immunol Immunopathol 1997 ; 83: 199-204.
-
(1997)
Clin Immunol Immunopathol
, vol.83
, pp. 199-204
-
-
Folzenlogen, D.1
Hofer, M.F.2
Leung, D.Y.3
Freed, J.H.4
Newell, M.K.5
-
16
-
-
0029862164
-
Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes
-
Koshy M., Berger D., Crow MK Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes. J Clin Invest 1996 ; 98: 826-837. (Pubitemid 26349188)
-
(1996)
Journal of Clinical Investigation
, vol.98
, Issue.3
, pp. 826-837
-
-
Koshy, M.1
Berger, D.2
Crow, M.K.3
-
17
-
-
0035525528
-
From T to B and back again: Positive feedback in systemic autoimmune disease
-
Shlomchik MJ, Craft JE, Mamula MJ From T to B and back again: positive feedback in systemic autoimmune disease. Nat Rev Immunol 2001 ; 1: 147-153.
-
(2001)
Nat Rev Immunol
, vol.1
, pp. 147-153
-
-
Shlomchik, M.J.1
Craft, J.E.2
Mamula, M.J.3
-
18
-
-
20344379893
-
CD28 extinction in human T cells: Altered functions and the program of T-cell senescence
-
Vallejo AN CD28 extinction in human T cells: altered functions and the program of T-cell senescence. Immunol Rev 2005 ; 205: 158-169.
-
(2005)
Immunol Rev
, vol.205
, pp. 158-169
-
-
Vallejo, A.N.1
-
19
-
-
0038481183
-
The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS
-
Wulff H., Calabresi PA, Allie R., et al. The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS. J Clin Invest 2003 ; 111: 1703-1713.
-
(2003)
J Clin Invest
, vol.111
, pp. 1703-1713
-
-
Wulff, H.1
Calabresi, P.A.2
Allie, R.3
-
20
-
-
0026080617
-
Increased oxidative metabolism in phytohemagglutinin-stimulated lymphocytes from patients with systemic lupus erythematosus is associated with serum SSA antibody
-
Benke PJ, Drisko J., Ahmad P. Increased oxidative metabolism in phytohemagglutinin-stimulated lymphocytes from patients with systemic lupus erythematosus is associated with serum SSA antibody. Biochem Med Metab Biol 1991 ; 45: 28-40.
-
(1991)
Biochem Med Metab Biol
, vol.45
, pp. 28-40
-
-
Benke, P.J.1
Drisko, J.2
Ahmad, P.3
-
21
-
-
0037310606
-
Bioenergetics of immune cells to assess rheumatic disease activity and efficacy of glucocorticoid treatment
-
Kuhnke A., Burmester GR, Krauss S., Buttgereit F. Bioenergetics of immune cells to assess rheumatic disease activity and efficacy of glucocorticoid treatment. Ann Rheum Dis 2003 ; 62: 133-139.
-
(2003)
Ann Rheum Dis
, vol.62
, pp. 133-139
-
-
Kuhnke, A.1
Burmester, G.R.2
Krauss, S.3
Buttgereit, F.4
-
24
-
-
0024344150
-
Studies of glycogen synthesis and the Krebs cycle by mass isotopomer analysis with [U-13C]glucose in rats
-
Katz J., Lee WN, Wals PA, Bergner EA Studies of glycogen synthesis and the Krebs cycle by mass isotopomer analysis with [U-13C]glucose in rats. J Biol Chem 1989 ; 264: 12994-13004.
-
(1989)
J Biol Chem
, vol.264
, pp. 12994-13004
-
-
Katz, J.1
Lee, W.N.2
Wals, P.A.3
Bergner, E.A.4
-
25
-
-
54249141095
-
Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival
-
Maciver NJ, Jacobs SR, Wieman HL, Wofford JA, Coloff JL, Rathmell JC Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival. J Leukoc Biol 2008 ; 84: 949-957.
-
(2008)
J Leukoc Biol
, vol.84
, pp. 949-957
-
-
MacIver, N.J.1
Jacobs, S.R.2
Wieman, H.L.3
Wofford, J.A.4
Coloff, J.L.5
Rathmell, J.C.6
-
26
-
-
0031573510
-
Resting B cells from autoimmune lupus-prone New Zealand Black and (New Zealand Black x New Zealand White)F1 mice are hyper-responsive to T cell-derived stimuli
-
Jongstra-Bilen J., Vukusic B., Boras K., Wither JE Resting B cells from autoimmune lupus-prone New Zealand Black and (New Zealand Black x New Zealand White)F1 mice are hyper-responsive to T cell-derived stimuli. J Immunol 1997 ; 159: 5810-5820.
-
(1997)
J Immunol
, vol.159
, pp. 5810-5820
-
-
Jongstra-Bilen, J.1
Vukusic, B.2
Boras, K.3
Wither, J.E.4
-
27
-
-
0031889353
-
Phenotypic and functional analysis of activated B cells of autoimmune NZB x NZW F1 mice
-
Ye YL, Suen JL, Chen YY, Chiang BL Phenotypic and functional analysis of activated B cells of autoimmune NZB x NZW F1 mice. Scand J Immunol 1998 ; 47: 122-126.
-
(1998)
Scand J Immunol
, vol.47
, pp. 122-126
-
-
Ye, Y.L.1
Suen, J.L.2
Chen, Y.Y.3
Chiang, B.L.4
-
28
-
-
0035867190
-
Telomere shortening and decreased replicative potential, contrasted by continued proliferation of telomerase-positive CD8+CD28(lo) T cells in patients with systemic lupus erythematosus
-
Honda M., Mengesha E., Albano S., et al. Telomere shortening and decreased replicative potential, contrasted by continued proliferation of telomerase-positive CD8+CD28(lo) T cells in patients with systemic lupus erythematosus. Clin Immunol 2001 ; 99: 211-221.
-
(2001)
Clin Immunol
, vol.99
, pp. 211-221
-
-
Honda, M.1
Mengesha, E.2
Albano, S.3
-
29
-
-
0031434175
-
Human T-cell clones in long-term culture as a model of immunosenescence
-
Pawelec G., Rehbein A., Haehnel K., Merl A., Adibzadeh M. Human T-cell clones in long-term culture as a model of immunosenescence. Immunol Rev 1997 ; 160: 31-42.
-
(1997)
Immunol Rev
, vol.160
, pp. 31-42
-
-
Pawelec, G.1
Rehbein, A.2
Haehnel, K.3
Merl, A.4
Adibzadeh, M.5
-
30
-
-
27544506096
-
Glycolysis versus TCA cycle in the primate brain as measured by combining 18F-FDG PET and 13C-NMR
-
Boumezbeur F., Besret L., Valette J., et al. Glycolysis versus TCA cycle in the primate brain as measured by combining 18F-FDG PET and 13C-NMR. J Cereb Blood Flow Metab 2005 ; 25: 1418-1423.
-
(2005)
J Cereb Blood Flow Metab
, vol.25
, pp. 1418-1423
-
-
Boumezbeur, F.1
Besret, L.2
Valette, J.3
-
31
-
-
0029658408
-
Changes in breath 13CO2/ 12CO2 during exercise of different intensities
-
Gautier JF, Pirnay F., Lacroix M., et al. Changes in breath 13CO2/ 12CO2 during exercise of different intensities. J Appl Physiol 1996 ; 81: 1096-1102.
-
(1996)
J Appl Physiol
, vol.81
, pp. 1096-1102
-
-
Gautier, J.F.1
Pirnay, F.2
Lacroix, M.3
-
32
-
-
0032927988
-
Hypothermia: Depression of tricarboxylic acid cycle flux and evidence for pentose phosphate shunt upregulation
-
Kaibara T., Sutherland GR, Colbourne F., Tyson RL Hypothermia: depression of tricarboxylic acid cycle flux and evidence for pentose phosphate shunt upregulation. J Neurosurg 1999 ; 90: 339-347.
-
(1999)
J Neurosurg
, vol.90
, pp. 339-347
-
-
Kaibara, T.1
Sutherland, G.R.2
Colbourne, F.3
Tyson, R.L.4
-
33
-
-
0035851102
-
Gleevec (STI571) influences metabolic enzyme activities and glucose carbon flow toward nucleic acid and fatty acid synthesis in myeloid tumor cells
-
Boren J., Cascante M., Marin S., et al. Gleevec (STI571) influences metabolic enzyme activities and glucose carbon flow toward nucleic acid and fatty acid synthesis in myeloid tumor cells. J Biol Chem 2001 ; 276: 37747-37753.
-
(2001)
J Biol Chem
, vol.276
, pp. 37747-37753
-
-
Boren, J.1
Cascante, M.2
Marin, S.3
-
34
-
-
78649254231
-
Decreased ERK and JNK signaling contribute to gene overexpression in ''senescentg'g' CD4+CD28- T cells through epigenetic mechanisms
-
Chen Y., Gorelik GJ, Strickland FM, Richardson BC Decreased ERK and JNK signaling contribute to gene overexpression in ''senescentg'g' CD4+CD28- T cells through epigenetic mechanisms. J Leukoc Biol 2009.
-
(2009)
J Leukoc Biol
-
-
Chen, Y.1
Gorelik, G.J.2
Strickland, F.M.3
Richardson, B.C.4
-
35
-
-
0020606245
-
Comparison of energy metabolism in human normal and neoplastic (Burkittg's lymphoma) lymphoid cells
-
Sariban-Sohraby S., Magrath IT, Balaban RS Comparison of energy metabolism in human normal and neoplastic (Burkittg's lymphoma) lymphoid cells. Cancer Res 1983 ; 43: 4662-4664.
-
(1983)
Cancer Res
, vol.43
, pp. 4662-4664
-
-
Sariban-Sohraby, S.1
Magrath, I.T.2
Balaban, R.S.3
-
36
-
-
0026816626
-
Mass isotopomer pattern and precursor-product relationship
-
Lee WN, Bergner EA, Guo ZK Mass isotopomer pattern and precursor-product relationship. Biol Mass Spectrom 1992 ; 21: 114-122.
-
(1992)
Biol Mass Spectrom
, vol.21
, pp. 114-122
-
-
Lee, W.N.1
Bergner, E.A.2
Guo, Z.K.3
-
37
-
-
0041629001
-
Breath [13CO2] recovery from an oral glucose load during exercise: Comparison between [U-13C] and [1,2-13C]glucose
-
Ruzzin J., Peronnet F., Tremblay J., Massicotte D., Lavoie C. Breath [13CO2] recovery from an oral glucose load during exercise: comparison between [U-13C] and [1,2-13C]glucose. J Appl Physiol 2003 ; 95: 477-482.
-
(2003)
J Appl Physiol
, vol.95
, pp. 477-482
-
-
Ruzzin, J.1
Peronnet, F.2
Tremblay, J.3
Massicotte, D.4
Lavoie, C.5
-
38
-
-
70149102426
-
Single valproic acid treatment inhibits glycogen and RNA ribose turnover while disrupting glucose-derived cholesterol synthesis in liver as revealed by the [U-C(6)]-d-glucose tracer in mice
-
Beger RD, Hansen DK, Schnackenberg LK, et al. Single valproic acid treatment inhibits glycogen and RNA ribose turnover while disrupting glucose-derived cholesterol synthesis in liver as revealed by the [U-C(6)]-d-glucose tracer in mice. Metabolomics 2009 ; 5: 336-345.
-
(2009)
Metabolomics
, vol.5
, pp. 336-345
-
-
Beger, R.D.1
Hansen, D.K.2
Schnackenberg, L.K.3
-
39
-
-
0030926003
-
Mitochondrial activation directly triggers the exocytosis of insulin in permeabilized pancreatic beta-cells
-
Maechler P., Kennedy ED, Pozzan T., Wollheim CB Mitochondrial activation directly triggers the exocytosis of insulin in permeabilized pancreatic beta-cells. EMBO J 1997 ; 16: 3833-3841.
-
(1997)
EMBO J
, vol.16
, pp. 3833-3841
-
-
Maechler, P.1
Kennedy, E.D.2
Pozzan, T.3
Wollheim, C.B.4
-
40
-
-
0031804597
-
Mass isotopomer study of the nonoxidative pathways of the pentose cycle with [1,2-13C2]glucose
-
Lee WN, Boros LG, Puigjaner J., Bassilian S., Lim S., Cascante M. Mass isotopomer study of the nonoxidative pathways of the pentose cycle with [1,2-13C2]glucose. Am J Physiol 1998 ; 274: E843-851.
-
(1998)
Am J Physiol
, vol.274
, pp. 843-851
-
-
Lee, W.N.1
Boros, L.G.2
Puigjaner, J.3
Bassilian, S.4
Lim, S.5
Cascante, M.6
-
41
-
-
0242411640
-
Defective RNA ribose synthesis in fibroblasts from patients with thiamine-responsive megaloblastic anemia (TRMA)
-
Boros LG, Steinkamp MP, Fleming JC, Lee WN, Cascante M., Neufeld EJ Defective RNA ribose synthesis in fibroblasts from patients with thiamine-responsive megaloblastic anemia (TRMA). Blood 2003 ; 102: 3556-3561.
-
(2003)
Blood
, vol.102
, pp. 3556-3561
-
-
Boros, L.G.1
Steinkamp, M.P.2
Fleming, J.C.3
Lee, W.N.4
Cascante, M.5
Neufeld, E.J.6
-
42
-
-
12344314276
-
Metabolic sensitivity of pancreatic tumour cell apoptosis to glycogen phosphorylase inhibitor treatment
-
Lee WN, Guo P., Lim S., et al. Metabolic sensitivity of pancreatic tumour cell apoptosis to glycogen phosphorylase inhibitor treatment. Br J Cancer 2004 ; 91: 2094-2100.
-
(2004)
Br J Cancer
, vol.91
, pp. 2094-2100
-
-
Lee, W.N.1
Guo, P.2
Lim, S.3
-
43
-
-
30544433533
-
ATP citrate lyase is an important component of cell growth and transformation
-
DOI 10.1038/sj.onc.1208773, PII 1208773
-
Bauer DE, Hatzivassiliou G., Zhao F., Andreadis C., Thompson CB ATP citrate lyase is an important component of cell growth and transformation. Oncogene 2005 ; 24: 6314-6322. (Pubitemid 43080054)
-
(2005)
Oncogene
, vol.24
, Issue.41
, pp. 6314-6322
-
-
Bauer, D.E.1
Hatzivassiliou, G.2
Zhao, F.3
Andreadis, C.4
Thompson, C.B.5
-
44
-
-
0026750101
-
ConA induced changes in energy metabolism of rat thymocytes
-
Buttgereit F., Brand MD, Muller M. ConA induced changes in energy metabolism of rat thymocytes. Biosci Rep 1992 ; 12: 381-386.
-
(1992)
Biosci Rep
, vol.12
, pp. 381-386
-
-
Buttgereit, F.1
Brand, M.D.2
Muller, M.3
-
45
-
-
0034887110
-
Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory
-
Homann D., Teyton L., Oldstone MB Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory. Nat Med 2001 ; 7: 913-919.
-
(2001)
Nat Med
, vol.7
, pp. 913-919
-
-
Homann, D.1
Teyton, L.2
Oldstone, M.B.3
-
46
-
-
0037083612
-
Cutting edge: CD4 and CD8 T cells are intrinsically different in their proliferative responses
-
Foulds KE, Zenewicz LA, Shedlock DJ, Jiang J., Troy AE, Shen H. Cutting edge: CD4 and CD8 T cells are intrinsically different in their proliferative responses. J Immunol 2002 ; 168: 1528-1532.
-
(2002)
J Immunol
, vol.168
, pp. 1528-1532
-
-
Foulds, K.E.1
Zenewicz, L.A.2
Shedlock, D.J.3
Jiang, J.4
Troy, A.E.5
Shen, H.6
-
47
-
-
0041381363
-
Similarities and differences in CD4+ and CD8+ effector and memory T cell generation
-
Seder RA, Ahmed R. Similarities and differences in CD4+ and CD8+ effector and memory T cell generation. Nat Immunol 2003 ; 4: 835-842.
-
(2003)
Nat Immunol
, vol.4
, pp. 835-842
-
-
Seder, R.A.1
Ahmed, R.2
-
48
-
-
33748752151
-
The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity
-
Schieke SM, Phillips D., McCoy Jr JP, et al. The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity. J Biol Chem 2006 ; 281: 27643-27652.
-
(2006)
J Biol Chem
, vol.281
, pp. 27643-27652
-
-
Schieke, S.M.1
Phillips, D.2
McCoy Jr., J.P.3
-
49
-
-
0033982427
-
Therapeutically targeting lymphocyte energy metabolism by high-dose glucocorticoids
-
Buttgereit F., Burmester GR, Brand MD Therapeutically targeting lymphocyte energy metabolism by high-dose glucocorticoids. Biochem Pharmacol 2000 ; 59: 597-603.
-
(2000)
Biochem Pharmacol
, vol.59
, pp. 597-603
-
-
Buttgereit, F.1
Burmester, G.R.2
Brand, M.D.3
-
50
-
-
33744462050
-
Antigen receptor-mediated changes in glucose metabolism in B lymphocytes: Role of phosphatidylinositol 3-kinase signaling in the glycolytic control of growth
-
Doughty CA, Bleiman BF, Wagner DJ, et al. Antigen receptor-mediated changes in glucose metabolism in B lymphocytes: role of phosphatidylinositol 3-kinase signaling in the glycolytic control of growth. Blood 2006 ; 107: 4458-4465.
-
(2006)
Blood
, vol.107
, pp. 4458-4465
-
-
Doughty, C.A.1
Bleiman, B.F.2
Wagner, D.J.3
-
51
-
-
27144496045
-
CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms
-
Parry RV, Chemnitz JM, Frauwirth KA, et al. CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms. Mol Cell Biol 2005 ; 25: 9543-9553.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 9543-9553
-
-
Parry, R.V.1
Chemnitz, J.M.2
Frauwirth, K.A.3
-
52
-
-
78649246723
-
Oxidative stress and homocysteine metabolism in patients with lupus nephritis
-
Moroni G., Novembrino C., Quaglini S., et al. Oxidative stress and homocysteine metabolism in patients with lupus nephritis. Lupus 2009.
-
(2009)
Lupus
-
-
Moroni, G.1
Novembrino, C.2
Quaglini, S.3
-
53
-
-
0015882341
-
The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen
-
Boveris A., Chance B. The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem J 1973 ; 134: 707-716.
-
(1973)
Biochem J
, vol.134
, pp. 707-716
-
-
Boveris, A.1
Chance, B.2
-
54
-
-
3042617625
-
Mitochondrial dysfunction in T cells of patients with systemic lupus erythematosus
-
Perl A., Gergely Jr.P., Banki K. Mitochondrial dysfunction in T cells of patients with systemic lupus erythematosus. Int Rev Immunol 2004 ; 23: 293-313.
-
(2004)
Int Rev Immunol
, vol.23
, pp. 293-313
-
-
Perl, A.1
Gergely, Jr.P.2
Banki, K.3
-
55
-
-
33845488705
-
Arsenic trioxide: A promising novel therapeutic agent for lymphoproliferative and autoimmune syndromes in MRL/lpr mice
-
Bobe P., Bonardelle D., Benihoud K., Opolon P., Chelbi-Alix MK Arsenic trioxide: A promising novel therapeutic agent for lymphoproliferative and autoimmune syndromes in MRL/lpr mice. Blood 2006 ; 108: 3967-3975.
-
(2006)
Blood
, vol.108
, pp. 3967-3975
-
-
Bobe, P.1
Bonardelle, D.2
Benihoud, K.3
Opolon, P.4
Chelbi-Alix, M.K.5
-
56
-
-
4644247643
-
Nitric oxide-dependent mitochondrial biogenesis generates Ca2+ signaling profile of lupus T cells
-
Nagy G., Barcza M., Gonchoroff N., Phillips PE, Perl A. Nitric oxide-dependent mitochondrial biogenesis generates Ca2+ signaling profile of lupus T cells. J Immunol 2004 ; 173: 3676-3683.
-
(2004)
J Immunol
, vol.173
, pp. 3676-3683
-
-
Nagy, G.1
Barcza, M.2
Gonchoroff, N.3
Phillips, P.E.4
Perl, A.5
-
57
-
-
2942635457
-
Mitochondrial hyperpolarization: A checkpoint of T-cell life, death and autoimmunity
-
Perl A., Gergely Jr.P., Nagy G., Koncz A., Banki K. Mitochondrial hyperpolarization: a checkpoint of T-cell life, death and autoimmunity. Trends Immunol 2004 ; 25: 360-367.
-
(2004)
Trends Immunol
, vol.25
, pp. 360-367
-
-
Perl, A.1
Gergely, Jr.P.2
Nagy, G.3
Koncz, A.4
Banki, K.5
-
58
-
-
67649407892
-
CD28(-) T cells: Their role in the age-associated decline of immune function
-
Weng NP, Akbar AN, Goronzy J. CD28(-) T cells: their role in the age-associated decline of immune function. Trends Immunol 2009 ; 30: 306-312.
-
(2009)
Trends Immunol
, vol.30
, pp. 306-312
-
-
Weng, N.P.1
Akbar, A.N.2
Goronzy, J.3
-
59
-
-
1642460103
-
Expression and activity analyses of CTLA4 in peripheral blood lymphocytes in systemic lupus erythematosus patients
-
Hirashima M., Fukazawa T., Abe K., Morita Y., Kusaoi M., Hashimoto H. Expression and activity analyses of CTLA4 in peripheral blood lymphocytes in systemic lupus erythematosus patients. Lupus 2004 ; 13: 24-31.
-
(2004)
Lupus
, vol.13
, pp. 24-31
-
-
Hirashima, M.1
Fukazawa, T.2
Abe, K.3
Morita, Y.4
Kusaoi, M.5
Hashimoto, H.6
-
60
-
-
34247884612
-
The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
-
Sharpe AH, Wherry EJ, Ahmed R., Freeman GJ The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection. Nat Immunol 2007 ; 8: 239-245.
-
(2007)
Nat Immunol
, vol.8
, pp. 239-245
-
-
Sharpe, A.H.1
Wherry, E.J.2
Ahmed, R.3
Freeman, G.J.4
-
61
-
-
0037064010
-
Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells
-
Fukuda R., Hirota K., Fan F., Jung YD, Ellis LM, Semenza GL Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells. J Biol Chem 2002 ; 277: 38205-38211.
-
(2002)
J Biol Chem
, vol.277
, pp. 38205-38211
-
-
Fukuda, R.1
Hirota, K.2
Fan, F.3
Jung, Y.D.4
Ellis, L.M.5
Semenza, G.L.6
-
62
-
-
0035012605
-
HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: Novel mechanism for HIF-1-mediated vascular endothelial growth factor expression
-
Laughner E., Taghavi P., Chiles K., Mahon PC, Semenza GL HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression. Mol Cell Biol 2001 ; 21: 3995-4004.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3995-4004
-
-
Laughner, E.1
Taghavi, P.2
Chiles, K.3
Mahon, P.C.4
Semenza, G.L.5
-
63
-
-
0030460724
-
Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1
-
Semenza GL, Jiang BH, Leung SW, et al. Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1. J Biol Chem 1996 ; 271: 32529-32537.
-
(1996)
J Biol Chem
, vol.271
, pp. 32529-32537
-
-
Semenza, G.L.1
Jiang, B.H.2
Leung, S.W.3
-
64
-
-
33644614520
-
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
-
Kim JW, Tchernyshyov I., Semenza GL, Dang CV HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab 2006 ; 3: 177-185.
-
(2006)
Cell Metab
, vol.3
, pp. 177-185
-
-
Kim, J.W.1
Tchernyshyov, I.2
Semenza, G.L.3
Dang, C.V.4
-
65
-
-
34247631690
-
The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis
-
Lum JJ, Bui T., Gruber M., et al. The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis. Genes Dev 2007 ; 21: 1037-1049.
-
(2007)
Genes Dev
, vol.21
, pp. 1037-1049
-
-
Lum, J.J.1
Bui, T.2
Gruber, M.3
-
66
-
-
34547687662
-
Shared signaling networks active in B cells isolated from genetically distinct mouse models of lupus
-
Wu T., Qin X., Kurepa Z., et al. Shared signaling networks active in B cells isolated from genetically distinct mouse models of lupus. J Clin Invest 2007 ; 117: 2186-2196.
-
(2007)
J Clin Invest
, vol.117
, pp. 2186-2196
-
-
Wu, T.1
Qin, X.2
Kurepa, Z.3
-
67
-
-
0036849728
-
Phosphorylation abnormalities: NZB mice exhibit a B-cell signalling defect
-
Tuscano JM, Hsu TC, McKnight H., Ansari AA, Gershwin ME Phosphorylation abnormalities: NZB mice exhibit a B-cell signalling defect. J Autoimmun 2002 ; 19: 103-109.
-
(2002)
J Autoimmun
, vol.19
, pp. 103-109
-
-
Tuscano, J.M.1
Hsu, T.C.2
McKnight, H.3
Ansari, A.A.4
Gershwin, M.E.5
-
68
-
-
24744449495
-
PI3Kgamma inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus
-
Barber DF, Bartolome A., Hernandez C., et al. PI3Kgamma inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus. Nat Med 2005 ; 11: 933-935.
-
(2005)
Nat Med
, vol.11
, pp. 933-935
-
-
Barber, D.F.1
Bartolome, A.2
Hernandez, C.3
-
69
-
-
0037133250
-
Abnormal B lymphocyte development and autoimmunity in hypoxia-inducible factor 1alpha- deficient chimeric mice
-
Kojima H., Gu H., Nomura S., et al. Abnormal B lymphocyte development and autoimmunity in hypoxia-inducible factor 1alpha- deficient chimeric mice. Proc Natl Acad Sci U S A 2002 ; 99: 2170-2174.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 2170-2174
-
-
Kojima, H.1
Gu, H.2
Nomura, S.3
-
70
-
-
0036802423
-
Benzodiazepine-induced superoxide signals B cell apoptosis: Mechanistic insight and potential therapeutic utility
-
Blatt NB, Bednarski JJ, Warner RE, et al. Benzodiazepine-induced superoxide signals B cell apoptosis: mechanistic insight and potential therapeutic utility. J Clin Invest 2002 ; 110: 1123-1132.
-
(2002)
J Clin Invest
, vol.110
, pp. 1123-1132
-
-
Blatt, N.B.1
Bednarski, J.J.2
Warner, R.E.3
-
71
-
-
0037333995
-
Attenuation of autoimmune disease in Fas-deficient mice by treatment with a cytotoxic benzodiazepine
-
Bednarski JJ, Warner RE, Rao T., et al. Attenuation of autoimmune disease in Fas-deficient mice by treatment with a cytotoxic benzodiazepine. Arthritis Rheum 2003 ; 48: 757-766.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 757-766
-
-
Bednarski, J.J.1
Warner, R.E.2
Rao, T.3
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