Activation of PPAR-γ and PTEN cascade participates in lovastatin-mediated accelerated differentiation of oligodendrocyte progenitor cells

GLIA

Volumn 58, Issue 14, 2010, Pages 1669-1685

  Paintlia, Ajaib S ^a   Paintlia, Manjeet K ^a   Singh, Avtar K ^b   Orak, John K ^a   Singh, Inderjit ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b RALPH H JOHNSON VA MEDICAL CENTER   (United States)

Author keywords

Differentiation; EAE MS; Lovastatin; Oligodendrocyte progenitors; PPAR PTEN; Remyelination; RhoA ROCK

Indexed keywords

CHOLESTEROL; MEVINOLIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL TISSUE; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CHOLESTEROL METABOLISM; CYTOTOXICITY; DEMYELINATING DISEASE; DEPLETION; ENZYME ACTIVATION; FLOW CYTOMETRY; GENETIC TRANSFECTION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MULTIPLE SCLEROSIS; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REMYELINIZATION; SPRAGUE DAWLEY RAT; STEM CELL; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; COCULTURE TECHNIQUES; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LOVASTATIN; NERVE FIBERS, MYELINATED; NEUROPROTECTIVE AGENTS; OLIGODENDROGLIA; PPAR GAMMA; PTEN PHOSPHOHYDROLASE; RATS; RATS, SPRAGUE-DAWLEY; STEM CELLS;

EID: 78349243590     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.21039     Document Type: Article

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