Negative impact of statins on oligodendrocytes and myelin formation in vitro and in vivo

Journal of Neuroscience

Volumn 28, Issue 50, 2008, Pages 13609-13614

  Klopfleisch, Steve ^a   Merkler, Doron ^b   Schmitz, Matthias ^a   Klöppner, Sabine ^a   Schedensack, Mariann ^b   Jeserich, Gunnar ^d   Althaus, Hans H ^a   Brück, Wolfgang ^b,c  

^a MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^d UNIVERSITY OF OSNABRÜCK   (Germany)

Author keywords

Cuprizone; GTPases; Multiple sclerosis; Oligodendrocytes; Remyelination; Statins

Indexed keywords

CUPRIZONE; MYELIN; RAS PROTEIN; RHO FACTOR; SIMVASTATIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MULTIPLE SCLEROSIS; MYELINATION; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; REMYELINIZATION;

ANIMALS; CELLS, CULTURED; FEMALE; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; IMMUNOBLOTTING; MICE; MICE, INBRED C57BL; MYELIN SHEATH; OLIGODENDROGLIA; RAS PROTEINS; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; SWINE;

EID: 58149377174     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2765-08.2008     Document Type: Article

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