메뉴 건너뛰기




Volumn 176, Issue 7, 2006, Pages 4385-4398

IL-4-induced peroxisome proliferator-activated receptor γ activation inhibits NF-κB trans activation in central nervous system (CNS) glial cells and protects oligodendrocyte progenitors under neuroinflammatory disease conditions: Implication for CNS-demyelinating diseases

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; ENZYME INHIBITOR; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 4; INTERLEUKIN 4 ANTIBODY; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; NUCLEAR FACTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN KINASE B; RECEPTOR ANTIBODY; SMALL INTERFERING RNA; SYNAPTOPHYSIN; AUTACOID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOXYGENASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE;

EID: 33646050051     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.176.7.4385     Document Type: Article
Times cited : (66)

References (61)
  • 2
    • 0032753320 scopus 로고    scopus 로고
    • Multiple sclerosis: B- and T-cell responses to the extracellular domain of the myelin oligodendrocyte glycoprotein
    • Lindert, R.-B., C. G. Haase, U. Brehm, C. Linington, H. Wekerle, and R. Hohlfeld. 1999. Multiple sclerosis: B- and T-cell responses to the extracellular domain of the myelin oligodendrocyte glycoprotein. Brain 122(Pt. 11): 2089-2100.
    • (1999) Brain , vol.122 , Issue.PART 11 , pp. 2089-2100
    • Lindert, R.-B.1    Haase, C.G.2    Brehm, U.3    Linington, C.4    Wekerle, H.5    Hohlfeld, R.6
  • 3
    • 0025909739 scopus 로고
    • Autoreactive T and B cells responding to myelin proteolipid protein in multiple sclerosis and controls
    • Sun, J. B., T. Olsson, W. Z. Wang, B. G. Xiao, V. Kostulas, S. Fredrikson, H. P. Ekre, and H. Link. 1991. Autoreactive T and B cells responding to myelin proteolipid protein in multiple sclerosis and controls. Eur. J. Immunol. 21: 1461-1468.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 1461-1468
    • Sun, J.B.1    Olsson, T.2    Wang, W.Z.3    Xiao, B.G.4    Kostulas, V.5    Fredrikson, S.6    Ekre, H.P.7    Link, H.8
  • 4
    • 0030697438 scopus 로고    scopus 로고
    • Predominance of the autoimmune response to myelin oligodendrocyte glycoprotein (MOG) in multiple sclerosis: Reactivity to the extracellular domain of MOG is directed against three main regions
    • Kerlero de Rosbo, N., M. Hoffman, I. Mendel, I. Yust, J. Kaye, R. Bakimer, S. Flechter, O. Abramsky, R. Milo, A. Karni, and A. Ben-Nun. 1997. Predominance of the autoimmune response to myelin oligodendrocyte glycoprotein (MOG) in multiple sclerosis: reactivity to the extracellular domain of MOG is directed against three main regions. Eur. J. Immunol. 27: 3059-3069.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 3059-3069
    • Kerlero De Rosbo, N.1    Hoffman, M.2    Mendel, I.3    Yust, I.4    Kaye, J.5    Bakimer, R.6    Flechter, S.7    Abramsky, O.8    Milo, R.9    Karni, A.10    Ben-Nun, A.11
  • 5
    • 0032950794 scopus 로고    scopus 로고
    • Identification of autoantibodies associated with myelin damage in multiple sclerosis
    • Genain, C. P., B. Cannella, S. L. Hauser, and C. S. Raine. 1999. Identification of autoantibodies associated with myelin damage in multiple sclerosis. Nat. Med. 5: 170-175.
    • (1999) Nat. Med. , vol.5 , pp. 170-175
    • Genain, C.P.1    Cannella, B.2    Hauser, S.L.3    Raine, C.S.4
  • 6
    • 0032839687 scopus 로고    scopus 로고
    • Demyelination in primate autoimmune encephalomyelitis and acute multiple sclerosis lesions: A case for antigen-specific antibody mediation
    • Raine, C. S., B. Cannella, S. L. Hauser, and C. P. Genain. 1999. Demyelination in primate autoimmune encephalomyelitis and acute multiple sclerosis lesions: a case for antigen-specific antibody mediation. Ann. Neurol. 46: 144-160.
    • (1999) Ann. Neurol. , vol.46 , pp. 144-160
    • Raine, C.S.1    Cannella, B.2    Hauser, S.L.3    Genain, C.P.4
  • 7
    • 0023931606 scopus 로고
    • Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/ oligodendrocyte glycoprotein
    • Linington, C., M. Bradl, H. Lassmann, C. Brunner, and K. Vass. 1988. Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/ oligodendrocyte glycoprotein. Am. J. Pathol. 130: 443-454.
    • (1988) Am. J. Pathol. , vol.130 , pp. 443-454
    • Linington, C.1    Bradl, M.2    Lassmann, H.3    Brunner, C.4    Vass, K.5
  • 8
    • 0023597814 scopus 로고
    • A monoclonal antibody against a myelin oligodendrocyte glycoprotein induces relapses and demyelination in central nervous system autoimmune disease
    • Schluesener, H. J., R. A. Sobel, C. Linington, and H. L. Weiner. 1987. A monoclonal antibody against a myelin oligodendrocyte glycoprotein induces relapses and demyelination in central nervous system autoimmune disease. J. Immunol. 139: 4016-4021.
    • (1987) J. Immunol. , vol.139 , pp. 4016-4021
    • Schluesener, H.J.1    Sobel, R.A.2    Linington, C.3    Weiner, H.L.4
  • 9
    • 0019469331 scopus 로고
    • Multiple sclerosis: Capping of surface immunoglobulin G on macrophages engaged in myelin breakdown
    • Prineas, J. W., and J. S. Graham. 1981. Multiple sclerosis: capping of surface immunoglobulin G on macrophages engaged in myelin breakdown. Ann. Neurol. 10: 149-158.
    • (1981) Ann. Neurol. , vol.10 , pp. 149-158
    • Prineas, J.W.1    Graham, J.S.2
  • 10
    • 0031748566 scopus 로고    scopus 로고
    • Multiple sclerosis: In situ evidence for antibody- and complement-mediated demyelination
    • Storch, M. K., S. Piddlesden, M. Haltia, M. Iivanainen, P. Morgan, and H. Lassmann. 1998. Multiple sclerosis: in situ evidence for antibody- and complement-mediated demyelination. Ann. Neurol. 43: 465-471.
    • (1998) Ann. Neurol. , vol.43 , pp. 465-471
    • Storch, M.K.1    Piddlesden, S.2    Haltia, M.3    Iivanainen, M.4    Morgan, P.5    Lassmann, H.6
  • 11
    • 0034601012 scopus 로고    scopus 로고
    • Failure to suppress the expansion of the activated CD4 T cell population in interferon γ-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis
    • Chu, C. Q., S. Wittmer, and D. K. Dalton. 2000. Failure to suppress the expansion of the activated CD4 T cell population in interferon γ-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis. J. Exp. Med. 192: 123-128.
    • (2000) J. Exp. Med. , vol.192 , pp. 123-128
    • Chu, C.Q.1    Wittmer, S.2    Dalton, D.K.3
  • 12
    • 0024215195 scopus 로고
    • Tumor necrosis factor mediates myelin damage in organotypic cultures of nervous tissue
    • Selmaj, K., and C. S. Raine. 1988. Tumor necrosis factor mediates myelin damage in organotypic cultures of nervous tissue. Ann. NY Acad. Sci. 540: 568-570.
    • (1988) Ann. NY Acad. Sci. , vol.540 , pp. 568-570
    • Selmaj, K.1    Raine, C.S.2
  • 13
    • 0031659763 scopus 로고    scopus 로고
    • Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: Models for multiple sclerosis with primary oligodendrogliopathy
    • Akassoglou, K., J. Bauer, G. Kassiotis, M. Pasparakis, H. Lassmann, G. Kollias, and L. Probert. 1998. Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy. Am. J. Pathol. 153: 801-813.
    • (1998) Am. J. Pathol. , vol.153 , pp. 801-813
    • Akassoglou, K.1    Bauer, J.2    Kassiotis, G.3    Pasparakis, M.4    Lassmann, H.5    Kollias, G.6    Probert, L.7
  • 14
    • 0038416100 scopus 로고    scopus 로고
    • Interleukin-1β promotes oligodendrocyte death through glutamate excitotoxicity
    • Takahashi, J. L., F. Giuliani, C. Power, Y. Imai, and V. W. Yong. 2003. Interleukin-1β promotes oligodendrocyte death through glutamate excitotoxicity. Ann. Neurol. 53: 588-595.
    • (2003) Ann. Neurol. , vol.53 , pp. 588-595
    • Takahashi, J.L.1    Giuliani, F.2    Power, C.3    Imai, Y.4    Yong, V.W.5
  • 15
    • 7244251521 scopus 로고    scopus 로고
    • Reversible demyelination, blood-brain barrier breakdown, and pronounced neutrophil recruitment induced by chronic IL-1 expression in the brain
    • Ferrari, C. C., A. M. Depino, F. Prada, N. Muraro, S. Campbell, O. Podhajcer, V. H. Perry, D. C. Anthony, and F. J. Pitossi. 2004. Reversible demyelination, blood-brain barrier breakdown, and pronounced neutrophil recruitment induced by chronic IL-1 expression in the brain. Am. J. Pathol. 165: 1827-1837.
    • (2004) Am. J. Pathol. , vol.165 , pp. 1827-1837
    • Ferrari, C.C.1    Depino, A.M.2    Prada, F.3    Muraro, N.4    Campbell, S.5    Podhajcer, O.6    Perry, V.H.7    Anthony, D.C.8    Pitossi, F.J.9
  • 16
    • 21244482466 scopus 로고    scopus 로고
    • Acute lipopolysaccharide-mediated injury in neonatal white matter glia: Role of TNF-α, IL-1β, and calcium
    • Sherwin, C., and R. Fern. 2005. Acute lipopolysaccharide-mediated injury in neonatal white matter glia: role of TNF-α, IL-1β, and calcium. J. Immunol. 175: 155-161.
    • (2005) J. Immunol. , vol.175 , pp. 155-161
    • Sherwin, C.1    Fern, R.2
  • 18
  • 19
    • 0035132294 scopus 로고    scopus 로고
    • LPS/IFN-γ cytotoxicity in oligodendroglial cells: Role of nitric oxide and protection by the anti-inflammatory cytokine IL-10
    • Molina-Holgado, E., J. M. Vela, A. Arévalo-Martín, and C. Guaza. 2001. LPS/IFN-γ cytotoxicity in oligodendroglial cells: role of nitric oxide and protection by the anti-inflammatory cytokine IL-10. Eur. J. Neurosci. 13: 493-502.
    • (2001) Eur. J. Neurosci. , vol.13 , pp. 493-502
    • Molina-Holgado, E.1    Vela, J.M.2    Arévalo-Martín, A.3    Guaza, C.4
  • 21
    • 0030890185 scopus 로고    scopus 로고
    • Astrocytes and microglia express inducible nitric oxide synthase in mice with experimental allergic encephalomyelitis
    • Tran, E. H., H. Hardin-Pouzet, G. Verge, and T. Owens. 1997. Astrocytes and microglia express inducible nitric oxide synthase in mice with experimental allergic encephalomyelitis. J. Neuroimmunol. 74: 121-129.
    • (1997) J. Neuroimmunol. , vol.74 , pp. 121-129
    • Tran, E.H.1    Hardin-Pouzet, H.2    Verge, G.3    Owens, T.4
  • 22
    • 0037334950 scopus 로고    scopus 로고
    • Nitric oxide metabolite determinations reveal continuous inflammation in multiple sclerosis
    • Danilov, A. I., M. Andersson, N. Bavand, N. P. Wiklund, T. Olsson, and L. Brundin. 2003. Nitric oxide metabolite determinations reveal continuous inflammation in multiple sclerosis. J. Neuroimmunol. 136: 112-118.
    • (2003) J. Neuroimmunol. , vol.136 , pp. 112-118
    • Danilov, A.I.1    Andersson, M.2    Bavand, N.3    Wiklund, N.P.4    Olsson, T.5    Brundin, L.6
  • 23
    • 0029150012 scopus 로고
    • Self-antigen-induced Th2 responses in experimental allergic encephalomyelitis (EAE)-resistant mice: Th2-mediated suppression of autoimmune disease
    • Cua, D. J., D. R. Hinton, and S. A. Stohlman. 1995. Self-antigen-induced Th2 responses in experimental allergic encephalomyelitis (EAE)-resistant mice: Th2-mediated suppression of autoimmune disease. J. Immunol. 155: 4052-4059.
    • (1995) J. Immunol. , vol.155 , pp. 4052-4059
    • Cua, D.J.1    Hinton, D.R.2    Stohlman, S.A.3
  • 24
    • 0026696776 scopus 로고
    • + suppressor cells of autoimmune encephalomyelitis respond to T cell receptor-associated determinants on effector cells by interleukin-4 secretion
    • + suppressor cells of autoimmune encephalomyelitis respond to T cell receptor-associated determinants on effector cells by interleukin-4 secretion. Eur. J. Immunol. 22: 1757-1763.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 1757-1763
    • Karpus, W.J.1    Gould, K.E.2    Swanborg, R.H.3
  • 26
    • 0032193696 scopus 로고    scopus 로고
    • IL-10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL-10- and IL-4-deficient and transgenic mice
    • Bettelli, E., M. P. Das, E. D. Howard, H. L. Weiner, R. A. Sobel, and V. K. Kuchroo. 1998. IL-10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL-10- and IL-4-deficient and transgenic mice. J. Immunol. 161: 3299-3306.
    • (1998) J. Immunol. , vol.161 , pp. 3299-3306
    • Bettelli, E.1    Das, M.P.2    Howard, E.D.3    Weiner, H.L.4    Sobel, R.A.5    Kuchroo, V.K.6
  • 28
    • 0031011146 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis in IL-4-deficient mice
    • Liblau, R., L. Steinman, and S. Brocke. 1997. Experimental autoimmune encephalomyelitis in IL-4-deficient mice. Int. Immunol. 9: 799-803.
    • (1997) Int. Immunol. , vol.9 , pp. 799-803
    • Liblau, R.1    Steinman, L.2    Brocke, S.3
  • 29
    • 0032427976 scopus 로고    scopus 로고
    • Treatment of multiple sclerosis with copolymer-1 (Copaxone): Implicating mechanisms of Th1 to Th2/Th3 immune-deviation
    • Miller, A., S. Shapiro, R. Gershtein, A. Kinarty, H. Rawashdeh, S. Honigman, and N. Lahat. 1998. Treatment of multiple sclerosis with copolymer-1 (Copaxone): implicating mechanisms of Th1 to Th2/Th3 immune-deviation. J. Neuroimmunol. 92: 113-121.
    • (1998) J. Neuroimmunol. , vol.92 , pp. 113-121
    • Miller, A.1    Shapiro, S.2    Gershtein, R.3    Kinarty, A.4    Rawashdeh, H.5    Honigman, S.6    Lahat, N.7
  • 30
    • 0037166073 scopus 로고    scopus 로고
    • Theiler's virus infection induces the expression of cyclooxygenase-2 in murine astrocytes: Inhibition by the anti-inflammatory cytokines interleukin-4 and interleukin-10
    • Molina-Holgado, E., A. Arévalo-Martín, S. Ortiz, J. M. Vela, and C. Guaza. 2002. Theiler's virus infection induces the expression of cyclooxygenase-2 in murine astrocytes: inhibition by the anti-inflammatory cytokines interleukin-4 and interleukin-10. Neurosci. Lett. 324: 237-241.
    • (2002) Neurosci. Lett. , vol.324 , pp. 237-241
    • Molina-Holgado, E.1    Arévalo-Martín, A.2    Ortiz, S.3    Vela, J.M.4    Guaza, C.5
  • 31
    • 0036319143 scopus 로고    scopus 로고
    • Interleukin-4 and interleukin-10 modulate nuclear factor κB activity and nitric oxide synthase-2 expression in Theiler's virus-infected brain astrocytes
    • Molina-Holgado, E., A. Arévalo-Martín, A. Castrillo, L. Boscá, J. M. Vela, and C. Guaza. 2002. Interleukin-4 and interleukin-10 modulate nuclear factor κB activity and nitric oxide synthase-2 expression in Theiler's virus-infected brain astrocytes. J. Neurochem. 81: 1242-1252.
    • (2002) J. Neurochem. , vol.81 , pp. 1242-1252
    • Molina-Holgado, E.1    Arévalo-Martín, A.2    Castrillo, A.3    Boscá, L.4    Vela, J.M.5    Guaza, C.6
  • 32
    • 6344278016 scopus 로고    scopus 로고
    • 2 inhibits the inflammatory response in primary rat astrocytes via down-regulating multiple steps in phosphatidylinositol 3-kinase-Akt-NF-κB-p300 pathway independent of peroxisome proliferator-activated receptor γ
    • 2 inhibits the inflammatory response in primary rat astrocytes via down-regulating multiple steps in phosphatidylinositol 3-kinase-Akt-NF-κB-p300 pathway independent of peroxisome proliferator-activated receptor γ. J. Immunol. 173: 5196-5208.
    • (2004) J. Immunol. , vol.173 , pp. 5196-5208
    • Giri, S.1    Rattan, R.2    Singh, A.K.3    Singh, I.4
  • 33
    • 24644456862 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitor augments survival and differentiation of oligodendrocyte progenitors in animal model of multiple sclerosis
    • Paintlia, A. S., M. K. Paintlia, M. Khan, T. Vollmer, A. K. Singh, and I. Singh. 2005. HMG-CoA reductase inhibitor augments survival and differentiation of oligodendrocyte progenitors in animal model of multiple sclerosis. FASEB J. 19: 1407-1421.
    • (2005) FASEB J. , vol.19 , pp. 1407-1421
    • Paintlia, A.S.1    Paintlia, M.K.2    Khan, M.3    Vollmer, T.4    Singh, A.K.5    Singh, I.6
  • 34
    • 0346848899 scopus 로고    scopus 로고
    • Correlation of very long chain fatty acid accumulation and inflammatory disease progression in childhood X-ALD: Implications for potential therapies
    • Paintlia, A. S., A. G. Gilg, M. Khan, A. K. Singh, E. Barbosa, and I. Singh. 2003. Correlation of very long chain fatty acid accumulation and inflammatory disease progression in childhood X-ALD: implications for potential therapies. Neurobiol. Dis. 14: 425-439.
    • (2003) Neurobiol. Dis. , vol.14 , pp. 425-439
    • Paintlia, A.S.1    Gilg, A.G.2    Khan, M.3    Singh, A.K.4    Barbosa, E.5    Singh, I.6
  • 35
  • 37
  • 38
    • 0141755110 scopus 로고    scopus 로고
    • Signal transduction pathways in mouse microglia N-11 cells activated by advanced glycation endproducts (AGEs)
    • Dukic-Stefanovic, S., J. Gasic-Milenkovic, W. Deuther-Conrad, and G. Münch. 2003. Signal transduction pathways in mouse microglia N-11 cells activated by advanced glycation endproducts (AGEs). J. Neurochem. 87: 44-55.
    • (2003) J. Neurochem. , vol.87 , pp. 44-55
    • Dukic-Stefanovic, S.1    Gasic-Milenkovic, J.2    Deuther-Conrad, W.3    Münch, G.4
  • 39
    • 1642499162 scopus 로고    scopus 로고
    • 5-aminoimidazole-4-carboxamide-1-β-4-ribofuranoside inhibits proinflammatory response in glial cells: A possible role of AMP-activated protein kinase
    • Giri, S., N. Nath, B. Smith, B. Viollet, A. K. Singh, and I. Singh. 2004. 5-aminoimidazole-4-carboxamide-1-β-4-ribofuranoside inhibits proinflammatory response in glial cells: a possible role of AMP-activated protein kinase. J. Neurosci. 24: 479-487.
    • (2004) J. Neurosci. , vol.24 , pp. 479-487
    • Giri, S.1    Nath, N.2    Smith, B.3    Viollet, B.4    Singh, A.K.5    Singh, I.6
  • 40
    • 4344661069 scopus 로고    scopus 로고
    • Experimental allergic encephalomyelitis is exacerbated in mice deficient for 12/15-lipoxygenase or 5-lipoxygenase
    • Emerson, M. R., and S. M. LeVine. 2004. Experimental allergic encephalomyelitis is exacerbated in mice deficient for 12/15-lipoxygenase or 5-lipoxygenase. Brain Res. 1021: 140-145.
    • (2004) Brain Res. , vol.1021 , pp. 140-145
    • Emerson, M.R.1    Levine, S.M.2
  • 41
  • 42
    • 0642345898 scopus 로고    scopus 로고
    • Axonal degeneration and progressive neurologic disability in multiple sclerosis
    • Bjartmar, C., and B. D. Trapp. 2003. Axonal degeneration and progressive neurologic disability in multiple sclerosis. Neurotox. Res. 5: 157-164.
    • (2003) Neurotox. Res. , vol.5 , pp. 157-164
    • Bjartmar, C.1    Trapp, B.D.2
  • 43
    • 0035096330 scopus 로고    scopus 로고
    • Heterogeneity of multiple sclerosis pathogenesis: Implications for diagnosis and therapy
    • Lassmann, H., W. Brück, and C. Lucchinetti. 2001. Heterogeneity of multiple sclerosis pathogenesis: implications for diagnosis and therapy. Trends Mol. Med. 7: 115-121.
    • (2001) Trends Mol. Med. , vol.7 , pp. 115-121
    • Lassmann, H.1    Brück, W.2    Lucchinetti, C.3
  • 44
    • 0032520788 scopus 로고    scopus 로고
    • Antisense knockdown of inducible nitric oxide synthase inhibits induction of experimental autoimmune encephalomyelitis in SJL/J mice
    • Ding, M., M. Zhang, J. L. Wong, N. E. Rogers, L. J. Ignarro, and R. R. Voskuhl. 1998. Antisense knockdown of inducible nitric oxide synthase inhibits induction of experimental autoimmune encephalomyelitis in SJL/J mice. J. Immunol. 160: 2560-2564.
    • (1998) J. Immunol. , vol.160 , pp. 2560-2564
    • Ding, M.1    Zhang, M.2    Wong, J.L.3    Rogers, N.E.4    Ignarro, L.J.5    Voskuhl, R.R.6
  • 46
    • 13844262625 scopus 로고    scopus 로고
    • Nitric-oxide-dependent and independent mechanisms of protection from CNS inflammation during Th1-mediated autoimmunity: Evidence from EAE in iNOS KO mice
    • Dalton, D. K., and S. Wittmer. 2005. Nitric-oxide-dependent and independent mechanisms of protection from CNS inflammation during Th1-mediated autoimmunity: evidence from EAE in iNOS KO mice. J. Neuroimmunol. 160: 110-121.
    • (2005) J. Neuroimmunol. , vol.160 , pp. 110-121
    • Dalton, D.K.1    Wittmer, S.2
  • 47
    • 1642281535 scopus 로고    scopus 로고
    • Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion
    • Barnett, M. H., and J. W. Prineas. 2004. Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion. Ann. Neurol. 55: 458-468.
    • (2004) Ann. Neurol. , vol.55 , pp. 458-468
    • Barnett, M.H.1    Prineas, J.W.2
  • 50
    • 0034583170 scopus 로고    scopus 로고
    • Regulation of macrophage gene expression by the peroxisome proliferator-activated receptor-γ
    • Ricote, M., J. S. Welch, and C. K. Glass. 2000. Regulation of macrophage gene expression by the peroxisome proliferator-activated receptor-γ. Horm. Res. 54: 275-280.
    • (2000) Horm. Res. , vol.54 , pp. 275-280
    • Ricote, M.1    Welch, J.S.2    Glass, C.K.3
  • 51
    • 0034711185 scopus 로고    scopus 로고
    • Induction of IκBα expression as a mechanism contributing to the anti-inflammatory activities of peroxisome proliferator-activated receptor-α activators
    • Delerive, P., P. Gervois, J. C. Fruchart, and B. Staels. 2000. Induction of IκBα expression as a mechanism contributing to the anti-inflammatory activities of peroxisome proliferator-activated receptor-α activators. J. Biol. Chem. 275: 36703-36707.
    • (2000) J. Biol. Chem. , vol.275 , pp. 36703-36707
    • Delerive, P.1    Gervois, P.2    Fruchart, J.C.3    Staels, B.4
  • 52
    • 0042867242 scopus 로고    scopus 로고
    • Troglitazone antagonizes tumor necrosis factor-α-induced reprogramming of adipocyte gene expression by inhibiting the transcriptional regulatory functions of NF-κB
    • Ruan, H., H. J. Pownall, and H. F. Lodish. 2003. Troglitazone antagonizes tumor necrosis factor-α-induced reprogramming of adipocyte gene expression by inhibiting the transcriptional regulatory functions of NF-κB. J. Biol. Chem. 278: 28181-28192.
    • (2003) J. Biol. Chem. , vol.278 , pp. 28181-28192
    • Ruan, H.1    Pownall, H.J.2    Lodish, H.F.3
  • 53
    • 0030892382 scopus 로고    scopus 로고
    • Interleukin-4 suppression of tumor necrosis factor α-stimulated E-selectin gene transcription is mediated by STAT6 antagonism of NF-κB
    • Bennett, B. L., R. Cruz, R. G. Lacson, and A. M. Manning. 1997. Interleukin-4 suppression of tumor necrosis factor α-stimulated E-selectin gene transcription is mediated by STAT6 antagonism of NF-κB. J. Biol. Chem. 272: 10212-10219.
    • (1997) J. Biol. Chem. , vol.272 , pp. 10212-10219
    • Bennett, B.L.1    Cruz, R.2    Lacson, R.G.3    Manning, A.M.4
  • 54
    • 0034537436 scopus 로고    scopus 로고
    • Interleukin-4/STAT6 represses STAT1 and NF-κB-dependent transcription through distinct mechanisms
    • Ohmori, Y., and T. A. Hamilton. 2000. Interleukin-4/STAT6 represses STAT1 and NF-κB-dependent transcription through distinct mechanisms. J. Biol. Chem. 275: 38095-38103.
    • (2000) J. Biol. Chem. , vol.275 , pp. 38095-38103
    • Ohmori, Y.1    Hamilton, T.A.2
  • 55
    • 0028327286 scopus 로고
    • Astrocyte responses to CNS injury
    • Norenberg, M. D. 1994. Astrocyte responses to CNS injury. J. Neuropathol. Exp. Neurol 53: 213-220.
    • (1994) J. Neuropathol. Exp. Neurol , vol.53 , pp. 213-220
    • Norenberg, M.D.1
  • 57
    • 0031809194 scopus 로고    scopus 로고
    • Functional IL-4 receptors on mouse astrocytes: IL-4 inhibits astrocyte activation and induces NGF secretion
    • Brodie, C., N. Goldreich, T. Haiman, and G. Kazimirsky. 1998. Functional IL-4 receptors on mouse astrocytes: IL-4 inhibits astrocyte activation and induces NGF secretion. J. Neuroimmunol. 81: 20-30.
    • (1998) J. Neuroimmunol. , vol.81 , pp. 20-30
    • Brodie, C.1    Goldreich, N.2    Haiman, T.3    Kazimirsky, G.4
  • 58
    • 0031957754 scopus 로고    scopus 로고
    • Collaboration of antibody and inflammation in clearance of rabies virus from the central nervous system
    • Hooper, D. C., K. Morimoto, M. Bette, E. Weihe, H. Koprowski, and B. Dietzschold. 1998. Collaboration of antibody and inflammation in clearance of rabies virus from the central nervous system. J. Virol. 72: 3711-3719.
    • (1998) J. Virol. , vol.72 , pp. 3711-3719
    • Hooper, D.C.1    Morimoto, K.2    Bette, M.3    Weihe, E.4    Koprowski, H.5    Dietzschold, B.6
  • 61
    • 4444297090 scopus 로고    scopus 로고
    • Frontline: Epitope recognition on the myelin/oligodendrocyte glycoprotein differentially influences disease phenotype and antibody effector functions in autoimmune demyelination
    • von Büdingen, H.-C., S. L. Hauser, J.-C. Ouallet, N. Tanuma, T. Menge, and C. P. Genain. 2004. Frontline: epitope recognition on the myelin/oligodendrocyte glycoprotein differentially influences disease phenotype and antibody effector functions in autoimmune demyelination. Eur. J. Immunol. 34: 2072-2083.
    • (2004) Eur. J. Immunol. , vol.34 , pp. 2072-2083
    • Von Büdingen, H.-C.1    Hauser, S.L.2    Ouallet, J.-C.3    Tanuma, N.4    Menge, T.5    Genain, C.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.