A soluble active mutant of HIV-1 integrase: Involvement of both the core and caeboxyl-terminal domains in multimerization

Journal of Biological Chemistry

Volumn 271, Issue 13, 1996, Pages 7712-7718

  Jenkins, Timothy M ^b   Engelman, Alan ^a,b   Ghirlando, Rodolfo ^b   Craigie, Robert ^b  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

INTEGRASE;

AMINO ACID SUBSTITUTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; HUMAN IMMUNODEFICIENCY VIRUS 1; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; VIRUS ASSEMBLY; VIRUS MORPHOLOGY; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; BASE SEQUENCE; DNA NUCLEOTIDYLTRANSFERASES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HIV-1; HUMANS; INTEGRASES; KINETICS; MACROMOLECULAR SUBSTANCES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OLIGODEOXYRIBONUCLEOTIDES; POINT MUTATION; RECOMBINANT PROTEINS; SOLUBILITY; SUBSTRATE SPECIFICITY; ULTRACENTRIFUGATION; VIRUS INTEGRATION; VIRUS REPLICATION;

EID: 0029980485     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.13.7712     Document Type: Article

References (42)

1. Whitcomb, J. M., and Hughes, S. H. (1992) Annu. Rev. Cell Biol. 8, 275-306
2. Goff, S. P. (1992) Annu. Rev. Genet. 26, 527-544
3. Vink, C., and Plasterk, R. H. A. (1993) Trends Genet. 9, 433-438
4. Fujiwara, T., and Mizuuchi, K. (1988) Cell 54, 497-504
5. Brown, P. O., Bowerman, B., Varmus, H. E., and Bishop, J. M. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 2525-2529
6. Sherman, P. A., and Fyfe, J. A. (1990) Proc. Natl. Acad. Sci. U.S.A. 87, 5119-5123
7. Bushman, F. D., and Craigie, R. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 1339-1343
8. LaFemina, R. L., Callahan, P. L., and Cordingley, M. G. (1991) J. Virol. 65, 5624-5630
9. Chow, S. A., Vincent, K. A., Ellison, V., and Brown, P. O. (1992) Science 255, 723-726
10. Drelich, M., Wilhelm, R., and Mous, J. (1992) Virology 188, 459-468
11. Vink, C., Oude Groeneger, A. A. M., and Plasterk, R. H. A. (1993) Nucleic Acids Res. 21, 1419-1425
12. Engelman,A.,Bushman,F.D., and Craigie, R. (1993)EMBO J. 12,3269-3275
13. Engelman, A., and Craigie, R. (1992) J. Virol. 66, 6361-6369
14. van Gent, D. C., Groeneger, A. A. M., and Plasterk, R. H. A. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 9598-9602
15. Leavitt, A. D., Shiue, L., and Varmus, H. E. (1993) J. Biol. Chem. 268, 2113-2119
16. Rowland, S. J., and Dyke, K. G. (1990) Mol Microbiol. 4, 961-975
17. Kulkosky, J., Jones, K. S., Katz, R. A., Mack, J. P. G., and Skalka, A. M. (1992) Mol Cell. Biol. 12, 2331-2338
18. Polard, P., and Chandler, M (1995) Mol. Microbiol. 15, 13-23
19. Jenkins, T. M., Hickman, A. B., Dyda, F., Ghirlando, R., Davies, D. R., and Craigie, R. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 6057-6061
20. Dyda, F., Hickman, A. B., Jenkins, T. M., Engelman, A., Craigie, R., and Davies, D. R. (1994) Science 266,1981-1986
21. Higuchi, R., Krummel, B., and Saiki, R. K. (1988) Nucleic Acids Res. 16, 7351-7367
22. Rosenberg, A. H., Lade, B. N., Chui, D. S., Lin, S. W., Dunn, J. J., and Studier, F. W. (1987) Gene (Amst.) 56, 125-135
23. Sanger, F., Nicklen, S., and Coulson, A. R. (1977) Proc. Natl. Acad. Sci. U. S. A. 74, 5463-5467
24. Studier, F. W., and Moffatt, B. A. (1986) J. Mol. Biol. 189, 113-130
25. Wetlaufer, D. B. (1962) Adv. Prot. Chem. 17, 303-390
26. Roark, D. E. (1976) Biophys. Chem. 5, 185-196
27. Perkins, S. J. (1986) Eur. J. Biochem. 157, 169-180
28. Engelman, A., Mizuuchi, K., and Craigie, R. (1991) Cell 67, 1211-1221
29. Engelman, A., and Craigie, R. (1995) J. Virol. 69, 5908-5911
30. Engelman, A., Englund, G., Orenstein, J. M., Martin, M. A., and Craigie, R. (1995) J. Virol. 69, 2729-2736
31. Willey, R. L., Smith, D. H., Lasky, L. A., Theodore, T. S., Earl, P. L., Moss, B., Capon, D. J., and Martin, M. A. (1988) J. Virol. 62,139-147
32. Ross, E. K., Buckler-White, A. J., Rabson, A. B., Englund, G., and Martin, M. A. (1991) J. Virol. 65, 4350-4358
33. Vink, C., Yeheskiely, E., van der Marel, G. A., van Boom, J. H., and Plasterk, R. H. A. (1991) Nucleic Acids Res. 19, 6691-6698
34. Shin, C. G., Taddeo, B., Haseltine, W. A., and Farnet, C. M. (1994) J. Virol. 68, 1633-1642
35. Ansari-Lari, M. A., Donehower, L. A., and Gibbs, R. A. (1995) Virology 211, 332-335
36. Lodi, P. J., Ernst, J. A., Kuszewski, J., Hickman, A. B., Engelman, A., Craigie, R., Clore, G. M., and Gronenborn, A. M. (1995) Biochemistry 34, 9826-9833
37. Eijkelenboom, A. P. A. M., Puras Lutzke, R. A., Boelens, R., Plasterk, R. H. A., Kaptein, R., and Hard, K. (1995) Nature Struct. Biol. 2, 807-810
38. van Gent, D. C., Vink, C., Groeneger, A. A. M., and Plasterk, R. H. A. (1993) EMBO J. 12, 3261-3267
39. Grandgenett, D. P., Vora, A. C., and Schiff, R. D. (1978) Virology 89, 119-132
40. Vincent, K. A., Ellison, V., Chow, S. A., and Brown, P. O. (1993) J. Virol. 67, 425-437
41. Jones, K. S., Coleman, J., Merkel, G. W., Laue, T. M., and Skalka, A. M. (1992) J. Biol. Chem. 267, 16037-16040
42. Bujacz, G., Jaskolski, M., Aleandratos, J., Wlodawer, A., Merkel, G., Katz, R. A., and Skalka, A. M. (1995) J. Mol. Biol. 253, 333-346