Mechanism of action of the HIV-1 integrase inhibitory peptide LEDGF 361-370

Biochemical and Biophysical Research Communications

Volumn 394, Issue 2, 2010, Pages 260-265

  Hayouka, Zvi ^a   Levin, Aviad ^a   Maes, Michal ^a   Hadas, Eran ^b   Shalev, Deborah E ^a   Volsky, David J ^b   Loyter, Abraham ^a   Friedler, Assaf ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b Department of Medicine   (United States)

Author keywords

Alanine scan; Fluorescence anisotropy; HIV 1; Homology modeling; Integrase; LEDGF p75; NMR; Peptides

Indexed keywords

INTEGRASE; INTEGRASE INHIBITOR; LENS EPITHELIUM DERIVED GROWTH FACTOR; PEPTIDE; VIRUS DNA;

ARTICLE; CELL STRAIN HEK293; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; HELA CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TREATMENT OUTCOME; VIRUS REPLICATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; HELA CELLS; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; HIV-1; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, INBRED STRAINS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; TRANSCRIPTION FACTORS; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 77950300642     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.02.100     Document Type: Article

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