Activation of calcium/calmodulin-dependent protein kinase IV and peroxisome proliferator-activated receptor γ coactivator-1α signaling pathway protects against neuronal injury and promotes mitochondrial biogenesis in the hippocampal CA1 subfield after transient global ischemia

Journal of Neuroscience Research

Volumn 88, Issue 14, 2010, Pages 3144-3154

  Chen, Shang Der ^a   Lin, Tsu Kung ^a   Lin, Jui Wei ^a   Yang, Ding I ^b   Lee, Su Ying ^a   Shaw, Fu Zen ^c   Liou, Chia Wei ^a   Chuang, Yao Chung ^a  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Calcium calmodulin dependent protein kinase IV; Hippocampus; Mitochondrial biogenesis; Peroxisome proliferator activated receptors coactivator 1 ; Transient global ischemia

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE IV; CYCLOOXYGENASE 1; MITOCHONDRIAL DNA; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN; PROTEIN SOD 2; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 2;

ANIMAL CELL; ARTICLE; BIOGENESIS; CONTROLLED STUDY; DOWN REGULATION; HIPPOCAMPUS; MALE; MITOCHONDRION; NERVE CELL LESION; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CA1 REGION, HIPPOCAMPAL; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 4; CELL DEATH; HYPOXIA-ISCHEMIA, BRAIN; ION CHANNELS; MALE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NERVE DEGENERATION; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTORS;

EID: 78149337609     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22469     Document Type: Article

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