-
1
-
-
0029834603
-
Immediate early gene expression in response to cerebral ischemia. Friend or foe?
-
Akins PT, Liu PK, Hsu CY. 1996. Immediate early gene expression in response to cerebral ischemia. Friend or foe? Stroke 27:1682-1687.
-
(1996)
Stroke
, vol.27
, pp. 1682-1687
-
-
Akins, P.T.1
Liu, P.K.2
Hsu, C.Y.3
-
2
-
-
0036082713
-
NMDA receptor activation mediates hydrogen peroxide-induced pathophysiology in rat hippocampal slices
-
Avshalumov MV, Rice ME. 2002. NMDA receptor activation mediates hydrogen peroxide-induced pathophysiology in rat hippocampal slices. J Neurophysiol 87:2896-2903.
-
(2002)
J Neurophysiol
, vol.87
, pp. 2896-2903
-
-
Avshalumov, M.V.1
Rice, M.E.2
-
3
-
-
13944278132
-
Mitochondria, oxidants, and aging
-
Balaban RS, Nemoto S, Finkel T. 2005. Mitochondria, oxidants, and aging. Cell 120:483-495.
-
(2005)
Cell
, vol.120
, pp. 483-495
-
-
Balaban, R.S.1
Nemoto, S.2
Finkel, T.3
-
4
-
-
0033796250
-
Mitochondrial free radical generation, oxidative stress, and aging
-
Cadenas E, Davies KJ. 2000. Mitochondrial free radical generation, oxidative stress, and aging. Free Radic Biol Med 29:222-230.
-
(2000)
Free Radic Biol Med
, vol.29
, pp. 222-230
-
-
Cadenas, E.1
Davies, K.J.2
-
5
-
-
0035149749
-
Reactive oxygen radicals in signaling and damage in the ischemic brain
-
Chan PH. 2001 Reactive oxygen radicals in signaling and damage in the ischemic brain. J Cereb Blood Flow Metab 21:12-14.
-
(2001)
J Cereb Blood Flow Metab
, vol.21
, pp. 12-14
-
-
Chan, P.H.1
-
6
-
-
33646547283
-
Reduction in molecular synthesis or enzyme activity of superoxide dismutases and catalase contributes to oxidative stress and neurogenic hypertension in spontaneously hypertensive rats
-
Chan SHH, Tai MH, Li CY, Chan JYH. 2006. Reduction in molecular synthesis or enzyme activity of superoxide dismutases and catalase contributes to oxidative stress and neurogenic hypertension in spontaneously hypertensive rats. Free Radic Biol Med 40:2028-2039.
-
(2006)
Free Radic Biol Med
, vol.40
, pp. 2028-2039
-
-
Chan, S.H.H.1
Tai, M.H.2
Li, C.Y.3
Chan, J.Y.H.4
-
7
-
-
33750374561
-
Effects of rosiglitazone on global ischemia-induced hippocampal injury and expression of mitochondrial uncoupling protein 2
-
Chen SD, Wu HY, Yang DI, Lee SY, Shaw FZ, Lin TK, Liou CW, Chuang YC. 2006. Effects of rosiglitazone on global ischemia-induced hippocampal injury and expression of mitochondrial uncoupling protein 2. Biochem Biophys Res Commun 351:198-203.
-
(2006)
Biochem Biophys Res Commun
, vol.351
, pp. 198-203
-
-
Chen, S.D.1
Wu, H.Y.2
Yang, D.I.3
Lee, S.Y.4
Shaw, F.Z.5
Lin, T.K.6
Liou, C.W.7
Chuang, Y.C.8
-
8
-
-
34047146391
-
Upregulation of nitric oxide synthase II contributes to apoptotic cell death in the hippocampal CA3 subfield via a cytochrome c/caspase-3 signaling cascade following induction of experimental temporal lobe status epilepticus in the rat
-
Chuang YC, Chen SD, Lin TK, Liou CW, Chang WN, Chan SH, Chang AY. 2007. Upregulation of nitric oxide synthase II contributes to apoptotic cell death in the hippocampal CA3 subfield via a cytochrome c/caspase-3 signaling cascade following induction of experimental temporal lobe status epilepticus in the rat. Neuropharmacology 52:1263-1273.
-
(2007)
Neuropharmacology
, vol.52
, pp. 1263-1273
-
-
Chuang, Y.C.1
Chen, S.D.2
Lin, T.K.3
Liou, C.W.4
Chang, W.N.5
Chan, S.H.6
Chang, A.Y.7
-
9
-
-
63849319380
-
Contribution of nitric oxide, superoxide anion, and peroxynitrite to activation of mitochondrial apoptotic signaling in hippocampal CA3 subfield following experimental temporal lobe status epilepticus
-
Chuang YC, Chen SD, Liou CW, Lin TK, Chang WN, Chan SHH, Chang AYW. 2009. Contribution of nitric oxide, superoxide anion, and peroxynitrite to activation of mitochondrial apoptotic signaling in hippocampal CA3 subfield following experimental temporal lobe status epilepticus. Epilepsia 50:731-746.
-
(2009)
Epilepsia
, vol.50
, pp. 731-746
-
-
Chuang, Y.C.1
Chen, S.D.2
Liou, C.W.3
Lin, T.K.4
Chang, W.N.5
Chan, S.H.H.6
Chang, A.Y.W.7
-
10
-
-
0345548705
-
Peroxisome proliferator-activated receptor γ coactivator-1-dependent uncoupling protein-2 expression in pancreatic islets of rats: A novel pathway for neural control of insulin secretion
-
De Souza CT, Gasparetti AL, Pereira-da-Silva M, Araujo EP, Carvalheira JB, Saad MJ, Boschero AC, Carneiro EM, Velloso LA. 2003. Peroxisome proliferator-activated receptor γ coactivator-1-dependent uncoupling protein-2 expression in pancreatic islets of rats: A novel pathway for neural control of insulin secretion. Diabetologia 46:1522-1531.
-
(2003)
Diabetologia
, vol.46
, pp. 1522-1531
-
-
De Souza, C.T.1
Gasparetti, A.L.2
Pereira-da-Silva, M.3
Araujo, E.P.4
Carvalheira, J.B.5
Saad, M.J.6
Boschero, A.C.7
Carneiro, E.M.8
Velloso, L.A.9
-
11
-
-
44349154324
-
Overexpression of UCP2 protects thalamic neurons following global ischemia in the mouse
-
Deierborg T, Wieloch T, Diano S, Warden CH, Horvath TL, Mattiasson G. 2008. Overexpression of UCP2 protects thalamic neurons following global ischemia in the mouse. J Cereb Blood Flow Metab 28:1186-1195.
-
(2008)
J Cereb Blood Flow Metab
, vol.28
, pp. 1186-1195
-
-
Deierborg, T.1
Wieloch, T.2
Diano, S.3
Warden, C.H.4
Horvath, T.L.5
Mattiasson, G.6
-
12
-
-
33747056618
-
Mitochondrial translocation of p53 mediates release of cytochrome c and hippocampal CA1 neuronal death after transient global cerebral ischemia in rats
-
Endo H, Kamada H, Nito C, Nishi T, Chan PH. 2006. Mitochondrial translocation of p53 mediates release of cytochrome c and hippocampal CA1 neuronal death after transient global cerebral ischemia in rats. J Neurosci 26:7974-7983.
-
(2006)
J Neurosci
, vol.26
, pp. 7974-7983
-
-
Endo, H.1
Kamada, H.2
Nito, C.3
Nishi, T.4
Chan, P.H.5
-
13
-
-
33644660537
-
PGC-1 coactivators: Inducible regulators of energy metabolism in health and disease
-
Finck BN, Kelly DP. 2006. PGC-1 coactivators: Inducible regulators of energy metabolism in health and disease. J Clin Invest 116:615-622.
-
(2006)
J Clin Invest
, vol.116
, pp. 615-622
-
-
Finck, B.N.1
Kelly, D.P.2
-
14
-
-
33845596500
-
Peroxisome proliferator-activated receptor γ coactivator 1 coactivators, energy homeostasis, and metabolism
-
Handschin C, Spiegelman BM. 2006. Peroxisome proliferator-activated receptor γ coactivator 1 coactivators, energy homeostasis, and metabolism. Endocr Rev 27:728-735.
-
(2006)
Endocr Rev
, vol.27
, pp. 728-735
-
-
Handschin, C.1
Spiegelman, B.M.2
-
15
-
-
0021891869
-
The mitochondrial electron transport and oxidative phosphorylation system
-
Hatefi Y. 1985. The mitochondrial electron transport and oxidative phosphorylation system. Annu Rev Biochem 54:1015-1069.
-
(1985)
Annu Rev Biochem
, vol.54
, pp. 1015-1069
-
-
Hatefi, Y.1
-
16
-
-
0141925706
-
Oxidative damage to the endoplasmic reticulum is implicated in ischemic neuronal cell death
-
Hayashi T, Saito A, Okuno S, Ferrand-Drake M, Dodd RL, Nishi T, Maier CM, Kinouchi H, Chan PH. 2003. Oxidative damage to the endoplasmic reticulum is implicated in ischemic neuronal cell death. J Cereb Blood Flow Metab 23:1117-1128.
-
(2003)
J Cereb Blood Flow Metab
, vol.23
, pp. 1117-1128
-
-
Hayashi, T.1
Saito, A.2
Okuno, S.3
Ferrand-Drake, M.4
Dodd, R.L.5
Nishi, T.6
Maier, C.M.7
Kinouchi, H.8
Chan, P.H.9
-
17
-
-
5344247243
-
PGC-1α: Turbocharging mitochondria
-
Houten SM, Auwerx J. 2004. PGC-1α: Turbocharging mitochondria. Cell 119:5-7.
-
(2004)
Cell
, vol.119
, pp. 5-7
-
-
Houten, S.M.1
Auwerx, J.2
-
18
-
-
17344371804
-
Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: Suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction
-
Keller JN, Kindy MS, Holtsberg FW, St Clair DK, Yen HC, Germeyer A, Steiner SM, Bruce-Keller AJ, Hutchins JB, Mattson MP. 1998. Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: Suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction. J Neurosci 18:687-697.
-
(1998)
J Neurosci
, vol.18
, pp. 687-697
-
-
Keller, J.N.1
Kindy, M.S.2
Holtsberg, F.W.3
St Clair, D.K.4
Yen, H.C.5
Germeyer, A.6
Steiner, S.M.7
Bruce-Keller, A.J.8
Hutchins, J.B.9
Mattson, M.P.10
-
19
-
-
0036192957
-
Manganese superoxide dismutase deficiency exacerbates cerebral infarction after focal cerebral ischemia/reperfusion in mice: Implications for the production and role of superoxide radicals
-
Kim GW, Kondo T, Noshita N, Chan PH. 2002. Manganese superoxide dismutase deficiency exacerbates cerebral infarction after focal cerebral ischemia/reperfusion in mice: Implications for the production and role of superoxide radicals. Stroke 33:809-815.
-
(2002)
Stroke
, vol.33
, pp. 809-815
-
-
Kim, G.W.1
Kondo, T.2
Noshita, N.3
Chan, P.H.4
-
21
-
-
5344252327
-
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1α null mice
-
Lin J, Wu PH, Tarr PT, Lindenberg KS, St-Pierre J, Zhang CY, Mootha VK, Jager S, Vianna CR, Reznick RM, Cui L, Manieri M, Donovan MX, Wu Z, Cooper MP, Fan MC, Rohas LM, Zavacki AM, Cinti S, Shulman GI, Lowell BB, Krainc D, Spiegelman BM. 2004. Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1α null mice. Cell 119:121-135.
-
(2004)
Cell
, vol.119
, pp. 121-135
-
-
Lin, J.1
Wu, P.H.2
Tarr, P.T.3
Lindenberg, K.S.4
St-Pierre, J.5
Zhang, C.Y.6
Mootha, V.K.7
Jager, S.8
Vianna, C.R.9
Reznick, R.M.10
Cui, L.11
Manieri, M.12
Donovan, M.X.13
Wu, Z.14
Cooper, M.P.15
Fan, M.C.16
Rohas, L.M.17
Zavacki, A.M.18
Cinti, S.19
Shulman, G.I.20
Lowell, B.B.21
Krainc, D.22
Spiegelman, B.M.23
more..
-
22
-
-
0041464712
-
Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma
-
Mattiasson G, Shamloo M, Gido G, Mathi K, Tomasevic G, Yi S, Warden CH, Castilho RF, Melcher T, Gonzalez-Zulueta M, Nikolich K, Wieloch T. 2003. Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma. Nat Med 9:1062-1068.
-
(2003)
Nat Med
, vol.9
, pp. 1062-1068
-
-
Mattiasson, G.1
Shamloo, M.2
Gido, G.3
Mathi, K.4
Tomasevic, G.5
Yi, S.6
Warden, C.H.7
Castilho, R.F.8
Melcher, T.9
Gonzalez-Zulueta, M.10
Nikolich, K.11
Wieloch, T.12
-
23
-
-
0038061012
-
A role for uncoupling protein-2 as a regulator of mitochondrial hydrogen peroxide generation
-
Negre-Salvayre A, Hirtz C, Carrera G, Cazenave R, Troly M, Salvayre R, Penicaud L, Casteilla L. 1997. A role for uncoupling protein-2 as a regulator of mitochondrial hydrogen peroxide generation. FASEB J 11:809-815.
-
(1997)
FASEB J
, vol.11
, pp. 809-815
-
-
Negre-Salvayre, A.1
Hirtz, C.2
Carrera, G.3
Cazenave, R.4
Troly, M.5
Salvayre, R.6
Penicaud, L.7
Casteilla, L.8
-
24
-
-
0035002886
-
Manganese superoxide dismutase affects cytochrome c release and caspase-9 activation after transient focal cerebral ischemia in mice
-
Noshita N, Sugawara T, Fujimura M, Morita-Fujimura Y, Chan PH. 2001. Manganese superoxide dismutase affects cytochrome c release and caspase-9 activation after transient focal cerebral ischemia in mice. J Cereb Blood Flow Metab 21:557-567.
-
(2001)
J Cereb Blood Flow Metab
, vol.21
, pp. 557-567
-
-
Noshita, N.1
Sugawara, T.2
Fujimura, M.3
Morita-Fujimura, Y.4
Chan, P.H.5
-
25
-
-
0023390566
-
Delayed hippo-campal damage in humans following cardiorespiratory arrest
-
Petito CK, Feldmann E, Pulsinelli WA, Plum F. 1987. Delayed hippo-campal damage in humans following cardiorespiratory arrest. Neurology 37:1281-1286.
-
(1987)
Neurology
, vol.37
, pp. 1281-1286
-
-
Petito, C.K.1
Feldmann, E.2
Pulsinelli, W.A.3
Plum, F.4
-
26
-
-
0037326196
-
Peroxisome proliferator-activated receptor-γcoactivator 1α (PGC-1α): Transcriptional coactivator and metabolic regulator
-
Puigserver P, Spiegelman BM. 2003. Peroxisome proliferator-activated receptor-γcoactivator 1α (PGC-1α): Transcriptional coactivator and metabolic regulator. Endocr Rev 24:78-90.
-
(2003)
Endocr Rev
, vol.24
, pp. 78-90
-
-
Puigserver, P.1
Spiegelman, B.M.2
-
27
-
-
0020067965
-
Temporal profile of neuronal damage in a model of transient forebrain ischemia
-
Pulsinelli WA, Brierley JB, Plum F. 1982. Temporal profile of neuronal damage in a model of transient forebrain ischemia. Ann Neurol 11:491-498.
-
(1982)
Ann Neurol
, vol.11
, pp. 491-498
-
-
Pulsinelli, W.A.1
Brierley, J.B.2
Plum, F.3
-
28
-
-
62449166389
-
PGC-1α expression decreases in the Alzheimer disease brain as a function of dementia
-
Qin W, Haroutunian V, Katsel P, Cardozo CP, Ho L, Buxbaum JD, Pasinetti GM. 2009. PGC-1α expression decreases in the Alzheimer disease brain as a function of dementia. Arch Neurol 66:352-361.
-
(2009)
Arch Neurol
, vol.66
, pp. 352-361
-
-
Qin, W.1
Haroutunian, V.2
Katsel, P.3
Cardozo, C.P.4
Ho, L.5
Buxbaum, J.D.6
Pasinetti, G.M.7
-
29
-
-
0034661024
-
Superoxides from mitochondrial complex III: The role of manganese superoxide dismutase
-
Raha S, McEachern GE, Myint AT, Robinson BH. 2000. Superoxides from mitochondrial complex III: The role of manganese superoxide dismutase. Free Radic Biol Med 29:170-180.
-
(2000)
Free Radic Biol Med
, vol.29
, pp. 170-180
-
-
Raha, S.1
McEachern, G.E.2
Myint, A.T.3
Robinson, B.H.4
-
30
-
-
0036308716
-
Effects of normobaric hyperoxia in a rat model of focal cerebral ischemia-reperfusion
-
Singhal AB, Wang X, Sumii T, Mori T, Lo EH. 2002. Effects of normobaric hyperoxia in a rat model of focal cerebral ischemia-reperfusion. J Cereb Blood Flow Metab 22:861-868.
-
(2002)
J Cereb Blood Flow Metab
, vol.22
, pp. 861-868
-
-
Singhal, A.B.1
Wang, X.2
Sumii, T.3
Mori, T.4
Lo, E.H.5
-
31
-
-
0025790342
-
Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease
-
Smith CD, Carney JM, Starke-Reed PE, Oliver CN, Stadtman ER, Floyd RA, Markesbery WR. 1991. Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease. Proc Natl Acad Sci USA 88:10540-10543.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 10540-10543
-
-
Smith, C.D.1
Carney, J.M.2
Starke-Reed, P.E.3
Oliver, C.N.4
Stadtman, E.R.5
Floyd, R.A.6
Markesbery, W.R.7
-
32
-
-
0021225723
-
The density and distribution of ischemic brain injury in the rat following 2-10 min of forebrain ischemia
-
Smith ML, Auer RN, Siesjo BK. 1984. The density and distribution of ischemic brain injury in the rat following 2-10 min of forebrain ischemia. Acta Neuropathol 64:319-332.
-
(1984)
Acta Neuropathol
, vol.64
, pp. 319-332
-
-
Smith, M.L.1
Auer, R.N.2
Siesjo, B.K.3
-
33
-
-
33749999530
-
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
-
St-Pierre J, Drori S, Uldry M, Silvaggi JM, Rhee J, Jager S, Handschin C, Zheng K, Lin J, Yang W, Simon DK, Bachoo R, Spiegelman BM. 2006. Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell 127:397-408.
-
(2006)
Cell
, vol.127
, pp. 397-408
-
-
St-Pierre, J.1
Drori, S.2
Uldry, M.3
Silvaggi, J.M.4
Rhee, J.5
Jager, S.6
Handschin, C.7
Zheng, K.8
Lin, J.9
Yang, W.10
Simon, D.K.11
Bachoo, R.12
Spiegelman, B.M.13
-
34
-
-
33749986298
-
Free radicals and antioxidants in normal physiological functions and human disease
-
Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J. 2007. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 39:44-84.
-
(2007)
Int J Biochem Cell Biol
, vol.39
, pp. 44-84
-
-
Valko, M.1
Leibfritz, D.2
Moncol, J.3
Cronin, M.T.4
Mazur, M.5
Telser, J.6
-
35
-
-
19444365211
-
PGC-1α regulates the mitochondrial antioxidant defense system in vascular endothelial cells
-
Valle I, Alvarez-Barrientos A, Arza E, Lamas S, Monsalve M. 2005. PGC-1α regulates the mitochondrial antioxidant defense system in vascular endothelial cells. Cardiovasc Res 66:562-573.
-
(2005)
Cardiovasc Res
, vol.66
, pp. 562-573
-
-
Valle, I.1
Alvarez-Barrientos, A.2
Arza, E.3
Lamas, S.4
Monsalve, M.5
-
36
-
-
0033538473
-
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
-
Wu Z, Puigserver P, Andersson U, Zhang C, Adelmant G, Mootha V, Troy A, Cinti S, Lowell B, Scarpulla RC, Spiegelman BM. 1999. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 98:115-124.
-
(1999)
Cell
, vol.98
, pp. 115-124
-
-
Wu, Z.1
Puigserver, P.2
Andersson, U.3
Zhang, C.4
Adelmant, G.5
Mootha, V.6
Troy, A.7
Cinti, S.8
Lowell, B.9
Scarpulla, R.C.10
Spiegelman, B.M.11
|