메뉴 건너뛰기




Volumn 6, Issue 3, 2010, Pages 179-196

Metabolomics of medicinal plants: The importance of multivariate analysis of analytical chemistry data

Author keywords

Marker metabolite; Medicinal plant; Metabolite fingerprint; Metabolomics; Multivariate analysis; Systems biology

Indexed keywords

BIOMOLECULES; CHEMICAL ANALYSIS; CONFORMAL MAPPING; DISCRIMINANT ANALYSIS; LEAST SQUARES APPROXIMATIONS; MULTIVARIANT ANALYSIS; PLANTS (BOTANY); PRINCIPAL COMPONENT ANALYSIS; QUALITY CONTROL; SELF ORGANIZING MAPS;

EID: 78049507708     PISSN: 15734099     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340910791760055     Document Type: Article
Times cited : (96)

References (112)
  • 1
    • 0033779923 scopus 로고    scopus 로고
    • Genetics and biochemistry of secondarymetabolites in plants: An evolutionary perspective
    • Pichersky, E.; Gang, D. R. Genetics and biochemistry of secondarymetabolites in plants: an evolutionary perspective. Trends PlantSci., 2000, 5, 439-445.
    • (2000) Trends PlantSci , vol.5 , pp. 439-445
    • Pichersky, E.1    Gang, D.R.2
  • 3
    • 34248216641 scopus 로고    scopus 로고
    • Virtual chromatographicresolution enhancement in cryoflow LC-NMR experiments viastatistical total correlation spectroscopy
    • Cloarec, O.; Campbell, A.; Tseng, L.H.; Braumann, U.; Spraul, M.; Scarfe, G.; Weaver, R.; Nicholson, J.K. Virtual chromatographicresolution enhancement in cryoflow LC-NMR experiments viastatistical total correlation spectroscopy. Anal. Chem., 2007, 79,3304-3311.
    • (2007) Anal. Chem , vol.79 , pp. 3304-3311
    • Cloarec, O.1    Campbell, A.2    Tseng, L.H.3    Braumann, U.4    Spraul, M.5    Scarfe, G.6    Weaver, R.7    Nicholson, J.K.8
  • 4
    • 33745937504 scopus 로고    scopus 로고
    • Bioinformatics and itsapplications in plant biology
    • Rhee, S.Y.; Dickerson, J.; Xu, D. Bioinformatics and itsapplications in plant biology. Annu. Rev. Plant Biol., 2006, 57,335-360.
    • (2006) Annu. Rev. Plant Biol , vol.57 , pp. 335-360
    • Rhee, S.Y.1    Dickerson, J.2    Xu, D.3
  • 5
    • 62549159971 scopus 로고    scopus 로고
    • Web-based resources for mass-spectrometry-based metabolomics: A user's guide
    • Tohge, T.; Fernie, A.R. Web-based resources for mass-spectrometry-based metabolomics: a user's guide. Phytochem.,2009, 70, 450-456.
    • (2009) Phytochem , vol.70 , pp. 450-456
    • Tohge, T.1    Fernie, A.R.2
  • 7
    • 37849020436 scopus 로고    scopus 로고
    • Decoding geneswith coexpression networks and metabolomics - 'majority report byprecogs'
    • Saito, K.; Hirai, M.Y.; Yonekura-Sakakibara, K. Decoding geneswith coexpression networks and metabolomics - 'majority report byprecogs'. Trends Plant Sci., 2007, 13, 36-43.
    • (2007) Trends Plant Sci , vol.13 , pp. 36-43
    • Saito, K.1    Hirai, M.Y.2    Yonekura-Sakakibara, K.3
  • 8
    • 33947307759 scopus 로고    scopus 로고
    • Plant metabolomics: Towards biologicalfunction and mechanism
    • Schauer, N.; Fernie, A.R. Plant metabolomics: towards biologicalfunction and mechanism. Trends Plant Sci., 2006, 11, 508-516.
    • (2006) Trends Plant Sci , vol.11 , pp. 508-516
    • Schauer, N.1    Fernie, A.R.2
  • 11
    • 68349097617 scopus 로고    scopus 로고
    • Quality control of herbal material and phytopharmaceuticalswith MS and NMR based metabolic fingerprinting
    • van der Kooy, F.; Maltese, F.; Choi, Y.H.; Kim, H.K.; Verpoorte, R. Quality control of herbal material and phytopharmaceuticalswith MS and NMR based metabolic fingerprinting. Planta Med.,2009, 75, 763-775.
    • (2009) Planta Med , vol.75 , pp. 763-775
    • van der Kooy, F.1    Maltese, F.2    Choi, Y.H.3    Kim, H.K.4    Verpoorte, R.5
  • 12
    • 40849135991 scopus 로고    scopus 로고
    • Metabolomics for phytomedicine researchand drug development
    • Shyur, L.F.; Yang, N.S. Metabolomics for phytomedicine researchand drug development. Curr. Opin. Chem. Biol., 2008, 12, 66-71.
    • (2008) Curr. Opin. Chem. Biol , vol.12 , pp. 66-71
    • Shyur, L.F.1    Yang, N.S.2
  • 14
    • 65049089975 scopus 로고    scopus 로고
    • Environmental metabolomics: Newinsights into earthworm ecotoxicity and contaminant bioavailabilityin soil
    • Simpson, M.J.; McKelvie, J.R. Environmental metabolomics: newinsights into earthworm ecotoxicity and contaminant bioavailabilityin soil. Anal. Bioanal. Chem., 2009, 394, 137-149.
    • (2009) Anal. Bioanal. Chem , vol.394 , pp. 137-149
    • Simpson, M.J.1    McKelvie, J.R.2
  • 15
    • 52649126218 scopus 로고    scopus 로고
    • Recent developments in environmental metabolomics
    • Viant, M.R. Recent developments in environmental metabolomics.Mol. Biosyst., 2008, 4, 980-986.
    • (2008) Mol. Biosyst , vol.4 , pp. 980-986
    • Viant, M.R.1
  • 16
    • 33847356478 scopus 로고    scopus 로고
    • Environmental metabolomics: A SWOT analysis(strengths, weaknesses, opportunities, and threats)
    • Miller, M.G. Environmental metabolomics: a SWOT analysis(strengths, weaknesses, opportunities, and threats). J. ProteomeRes., 2007, 6, 540-545.
    • (2007) J. ProteomeRes , vol.6 , pp. 540-545
    • Miller, M.G.1
  • 17
    • 58149330201 scopus 로고    scopus 로고
    • Metabolomics-assisted breeding: A viableoption for crop improvement?
    • Fernie, A.R.; Schauer, N. Metabolomics-assisted breeding: a viableoption for crop improvement? Trends Genet., 2009, 25, 39-48.
    • (2009) Trends Genet , vol.25 , pp. 39-48
    • Fernie, A.R.1    Schauer, N.2
  • 20
    • 38149013060 scopus 로고    scopus 로고
    • Plant metabolomicsand its potential application for human nutrition
    • Hall, R.D.; Brouwer, I.D.; Fitzgerald, M.A. Plant metabolomicsand its potential application for human nutrition. Physiol. Plant.,2008, 132, 162-175.
    • (2008) Physiol. Plant , vol.132 , pp. 162-175
    • Hall, R.D.1    Brouwer, I.D.2    Fitzgerald, M.A.3
  • 21
    • 0036500993 scopus 로고    scopus 로고
    • Systems biology, a brief overview
    • Kitano, H. Systems biology, a brief overview. Nature, 2002, 295,1662-1664.
    • (2002) Nature , vol.295 , pp. 1662-1664
    • Kitano, H.1
  • 23
    • 0035160371 scopus 로고    scopus 로고
    • A functionalgenomic strategy that uses metabolome data to reveal thephenotype of silentmutations
    • Raamskonk, L.M.; Teusink, B.; Broadhurst, D. A functionalgenomic strategy that uses metabolome data to reveal thephenotype of silentmutations. Nat. Biotech., 2001, 19, 45-50.
    • (2001) Nat. Biotech , vol.19 , pp. 45-50
    • Raamskonk, L.M.1    Teusink, B.2    Broadhurst, D.3
  • 24
    • 0037444362 scopus 로고    scopus 로고
    • Contemporary issues intoxicology: The role of metabonomics in toxicology and itsevaluation by the COMET project
    • Lindon, J.C.; Nicholson, J.K.; Holmes, E. Contemporary issues intoxicology: the role of metabonomics in toxicology and itsevaluation by the COMET project. Toxicol. Appl. Pharmacol.,2003, 187, 137.
    • (2003) Toxicol. Appl. Pharmacol , vol.187 , pp. 137
    • Lindon, J.C.1    Nicholson, J.K.2    Holmes, E.3
  • 27
    • 67651211781 scopus 로고    scopus 로고
    • Application of systems biologytechnology in research of traditional Chinense medicine
    • Ping, L.; Li-ping, Y., Yue-wen, G. Application of systems biologytechnology in research of traditional Chinense medicine. J. Trad.Chinese Med., 2009, 29, 153-157.
    • (2009) J. Trad.Chinese Med , vol.29 , pp. 153-157
    • Ping, L.1    Li-Ping, Y.2    Yue-Wen, G.3
  • 28
    • 8844227477 scopus 로고    scopus 로고
    • Strategyfor analysis and screening of bioactive compounds in traditionalChinese medicines
    • Huang, X.; Long, L.; Li, X.; Chen, X.; Guo, M.; Zou, H. Strategyfor analysis and screening of bioactive compounds in traditionalChinese medicines. J. Chromatogr., B, 2004, 812, 71-84.
    • (2004) J. Chromatogr., B , vol.812 , pp. 71-84
    • Huang, X.1    Long, L.2    Li, X.3    Chen, X.4    Guo, M.5    Zou, H.6
  • 29
    • 0003952242 scopus 로고    scopus 로고
    • 15th ed, Ministry of Health, Labourand Welfare of Japan
    • The Japanese Pharmacopoeia, 15th ed, Ministry of Health, Labourand Welfare of Japan, 2006.
    • (2006) The Japanese Pharmacopoeia
  • 30
    • 23444455795 scopus 로고    scopus 로고
    • Ayurveda
    • Padma, T.V. Ayurveda. Nature, 2005, 436, 486.
    • (2005) Nature , vol.436 , pp. 486
    • Padma, T.V.1
  • 33
    • 9144234156 scopus 로고    scopus 로고
    • Quality control of herbal medicines
    • Liang, Y.; Xie, P.; Chan, K. Quality control of herbal medicines. J.Chromatogr. B, 2004, 812, 53-70.
    • (2004) J.Chromatogr. B , vol.812 , pp. 53-70
    • Liang, Y.1    Xie, P.2    Chan, K.3
  • 34
    • 35748985579 scopus 로고    scopus 로고
    • Massspectral profiling: An effective tool for quality control of herbalmedicines
    • Zeng, Z.; Liang, Y.; Chau, F.; Chen, S.; Daniel, M.; Chan, C. Massspectral profiling: an effective tool for quality control of herbalmedicines. Anal. Chim. Acta, 2007, 604, 89-98.
    • (2007) Anal. Chim. Acta , vol.604 , pp. 89-98
    • Zeng, Z.1    Liang, Y.2    Chau, F.3    Chen, S.4    Daniel, M.5    Chan, C.6
  • 35
    • 0025489075 scopus 로고
    • Self-organizing map
    • Kohonen, T. Self-organizing map. Proc. IEEE, 1990, 78, 1464-1480.
    • (1990) Proc. IEEE , vol.78 , pp. 1464-1480
    • Kohonen, T.1
  • 36
    • 0035802405 scopus 로고    scopus 로고
    • Analysis of codon usage diversity ofbacterial gene with a self-organizing map (SOM)
    • Kanaya, S.; Kinouchi, M.; Abe, T.; Kudo, Y.; Yamada, Y.; Nishi, T.; Mori, H.; Ikemura, T. Analysis of codon usage diversity ofbacterial gene with a self-organizing map (SOM). Gene, 2001, 276,89-99.
    • (2001) Gene , vol.276 , pp. 89-99
    • Kanaya, S.1    Kinouchi, M.2    Abe, T.3    Kudo, Y.4    Yamada, Y.5    Nishi, T.6    Mori, H.7    Ikemura, T.8
  • 38
  • 39
    • 0016359052 scopus 로고
    • Correspondence analysis: A neglected multivariatemethod
    • Hill, M.O. Correspondence analysis: a neglected multivariatemethod. Appl. Stat., 1974, 23, 340-354.
    • (1974) Appl. Stat , vol.23 , pp. 340-354
    • Hill, M.O.1
  • 40
    • 0024507166 scopus 로고
    • Spectral map analysis: Factorial analysis of contrasts,especially from log ratios
    • Lewi, L. Spectral map analysis: factorial analysis of contrasts,especially from log ratios. Chem. Int. Lab. Syst., 1989, 5, 105-116.
    • (1989) Chem. Int. Lab. Syst , vol.5 , pp. 105-116
    • Lewi, L.1
  • 41
    • 0032184873 scopus 로고    scopus 로고
    • Chinese herbs: A clinical review of Astragalus,Ligusticum, and Schizandrae
    • Sinclair, S. Chinese herbs: a clinical review of Astragalus,Ligusticum, and Schizandrae. Altern. Med. Rev., 1998, 3, 338-344.
    • (1998) Altern. Med. Rev , vol.3 , pp. 338-344
    • Sinclair, S.1
  • 42
    • 45849152052 scopus 로고    scopus 로고
    • Quality evaluation of Astragali Radix using amultivariate statistical approach
    • Tanaka, K.; Tamura, T.; Fukuda, S.; Batkhuu, J.; Sanchir, C.; Komatsu, K. Quality evaluation of Astragali Radix using amultivariate statistical approach. Phytochemistry, 2008, 69, 2081-2087.
    • (2008) Phytochemistry , vol.69 , pp. 2081-2087
    • Tanaka, K.1    Tamura, T.2    Fukuda, S.3    Batkhuu, J.4    Sanchir, C.5    Komatsu, K.6
  • 43
    • 68349127502 scopus 로고    scopus 로고
    • Medicinal use of cannabis in the UnitedStates: Historical perspectives, current trends, and future directions
    • Aggarwal, S.K.; Carter, G.T.; Sullivan, M.D.; ZumBrunnen, C.; Morrill, R.; Mayer, J.D. Medicinal use of cannabis in the UnitedStates: historical perspectives, current trends, and future directions.J. Opioid. Manage., 2009, 5, 153-168.
    • (2009) J. Opioid. Manage , vol.5 , pp. 153-168
    • Aggarwal, S.K.1    Carter, G.T.2    Sullivan, M.D.3    Zumbrunnen, C.4    Morrill, R.5    Mayer, J.D.6
  • 44
    • 42349104678 scopus 로고    scopus 로고
    • Cannabinomimeticcontrol of mast cell mediator release: New perspective in chronicinflammation
    • De Filippis, D.; D'Amico, A.; Iuvone, T. Cannabinomimeticcontrol of mast cell mediator release: new perspective in chronicinflammation. J. Neuroendocrinol., 2008, 20(Suppl. 1), 20-25.
    • (2008) J. Neuroendocrinol , vol.20 , Issue.SUPPL. 1 , pp. 20-25
    • de Filippis, D.1    D'amico, A.2    Iuvone, T.3
  • 45
    • 54749090433 scopus 로고    scopus 로고
    • Potential roles of(endo)cannabinoids in the treatment of glaucoma: From intraocularpressure control to neuroprotection
    • Nucci, C.; Bari, M.; Spanò, A.; Corasaniti, M.; Bagetta, G.; Maccarrone, M.; Morrone, L.A. Potential roles of(endo)cannabinoids in the treatment of glaucoma: from intraocularpressure control to neuroprotection. Prog. Brain Res., 2008, 173,451-464.
    • (2008) Prog. Brain Res , vol.173 , pp. 451-464
    • Nucci, C.1    Bari, M.2    Spanò, A.3    Corasaniti, M.4    Bagetta, G.5    Maccarrone, M.6    Morrone, L.A.7
  • 48
    • 33947309772 scopus 로고    scopus 로고
    • Qualitycontrol and discrimination of Pericarpium Citri Reticulatae andPericarpium Citri Reticulatae Viride based on high-performanceliquid chromatographic fingerprints and multivariate statisticalanalysis
    • Yi, L.Z.; Yuan, D.L.; Liang, Y.Z.; Xie, P.S.; Zhao, Y. Qualitycontrol and discrimination of Pericarpium Citri Reticulatae andPericarpium Citri Reticulatae Viride based on high-performanceliquid chromatographic fingerprints and multivariate statisticalanalysis. Anal. Chim. Acta., 2007, 588, 207-215.
    • (2007) Anal. Chim. Acta , vol.588 , pp. 207-215
    • Yi, L.Z.1    Yuan, D.L.2    Liang, Y.Z.3    Xie, P.S.4    Zhao, Y.5
  • 49
    • 67651071980 scopus 로고    scopus 로고
    • Discrimination of three medicinal materials from the Citrus genusby HPLC fingerprint coupled with two complementary software
    • Qin, X-M.; Dai, Y-T.; Zhang, L-Z.; Guo, X-Q.; Shao, H-X.Discrimination of three medicinal materials from the Citrus genusby HPLC fingerprint coupled with two complementary software.Phytochem. Anal., 2009, 20, 307-313.
    • (2009) Phytochem. Anal , vol.20 , pp. 307-313
    • Qin, X.-M.1    Dai, Y.-T.2    Zhang, L.-Z.3    Guo, X.-Q.4    Shao, H.-X.5
  • 50
    • 0015211527 scopus 로고
    • Plant antitumor agents. VI. The isolation and structure of taxol, anovel antileukemic and antitumor agent from Taxus brevifolia
    • Wani, M.C.; Taylor, H.L.; Wall, M.E.; Coggon, P.; McPhail, A.T.Plant antitumor agents. VI. The isolation and structure of taxol, anovel antileukemic and antitumor agent from Taxus brevifolia. J.Am. Chem. Soc., 1971, 93, 2325-2327.
    • (1971) J.Am. Chem. Soc , vol.93 , pp. 2325-2327
    • Wani, M.C.1    Taylor, H.L.2    Wall, M.E.3    Coggon, P.4    McPhail, A.T.5
  • 51
    • 0032718086 scopus 로고    scopus 로고
    • The taxane diterpenoids
    • Baloglu, E.; Kingston, D.G.I. The taxane diterpenoids. J. Nat.Prod., 1999, 62, 1448-1472.
    • (1999) J. Nat.Prod , vol.62 , pp. 1448-1472
    • Baloglu, E.1    Kingston, D.G.I.2
  • 52
    • 67649786543 scopus 로고    scopus 로고
    • Taxol biosynthesis:Identification and characterization of two acetyl CoA:Taxoid-O-acetyl transferases that divert pathway flux away from Taxolproduction
    • Hampel, D.; Mau, C.J.; Croteau, R.B. Taxol biosynthesis:Identification and characterization of two acetyl CoA:taxoid-O-acetyl transferases that divert pathway flux away from Taxolproduction. Arch. Biochem. Biophys., 2009, 487, 91-97.
    • (2009) Arch. Biochem. Biophys , vol.487 , pp. 91-97
    • Hampel, D.1    Mau, C.J.2    Croteau, R.B.3
  • 53
    • 0035838940 scopus 로고    scopus 로고
    • Croteau, R.Taxol biosynthetic genes
    • Walker, K.; Croteau, R.Taxol biosynthetic genes. Phytochemistry,2001, 58, 1-7.
    • (2001) Phytochemistry , vol.58 , pp. 1-7
    • Walker, K.1
  • 54
    • 0034142272 scopus 로고    scopus 로고
    • Screening ofthe needles of different yew species and cultivars for paclitaxel andrelated taxoids
    • van Rozendaal, E.L.; Lelyveld, G.P.; van Beek, T.A. Screening ofthe needles of different yew species and cultivars for paclitaxel andrelated taxoids. Phytochemistry, 2000, 53, 383-389.
    • (2000) Phytochemistry , vol.53 , pp. 383-389
    • van Rozendaal, E.L.1    Lelyveld, G.P.2    van Beek, T.A.3
  • 58
    • 39049139745 scopus 로고    scopus 로고
    • Multivariate chromatographicfingerprint preparation and authentication of plant material fromthe genus Bauhinia
    • Soares, P.K.; Scarminio, I.S. Multivariate chromatographicfingerprint preparation and authentication of plant material fromthe genus Bauhinia. Phytochem. Anal., 2008, 19, 78-85.
    • (2008) Phytochem. Anal , vol.19 , pp. 78-85
    • Soares, P.K.1    Scarminio, I.S.2
  • 59
    • 0042315141 scopus 로고    scopus 로고
    • Differentiation of species of the Baccharis genus by HPLC andchemometric methods
    • Lonni, A.A.S.G.; Scarminio, I.S.; Silva, L.M.C.; Trevisan, D.T.Differentiation of species of the Baccharis genus by HPLC andchemometric methods. Anal. Sci., 2003, 19, 1013-1018.
    • (2003) Anal. Sci , vol.19 , pp. 1013-1018
    • Lonni, A.A.S.G.1    Scarminio, I.S.2    Silva, L.M.C.3    Trevisan, D.T.4
  • 60
    • 0030270228 scopus 로고    scopus 로고
    • Engineeringapplications of the self-organizing map
    • Kohonen, T.; Oja, E.; Simula, O.; Visa, A.; Kangas, J. Engineeringapplications of the self-organizing map. Proc. IEEE, 1996, 84,1358-1384.
    • (1996) Proc. IEEE , vol.84 , pp. 1358-1384
    • Kohonen, T.1    Oja, E.2    Simula, O.3    Visa, A.4    Kangas, J.5
  • 62
    • 0001052307 scopus 로고    scopus 로고
    • New observations on the secondary chemistry of worldEphedra (Ephedraceae)
    • Caveney, S.; Charlet, D.A.; Freitag, H.; Maier-Stolte, M.; Starratt, A.N. New observations on the secondary chemistry of worldEphedra (Ephedraceae). Am. J. Bot., 2001, 88, 1199-1208.
    • (2001) Am. J. Bot , vol.88 , pp. 1199-1208
    • Caveney, S.1    Charlet, D.A.2    Freitag, H.3    Maier-Stolte, M.4    Starratt, A.N.5
  • 64
    • 76549093963 scopus 로고    scopus 로고
    • Metabolome analysis ofEphedra plants with different contents of ephedrine alkaloids byusing UPLC-Q-TOF-MS
    • Okada, T.; Nakamura, Y.; Kanaya, S.; Takano, A.; Malla, K.J.; Nakane, T.; Kitayama, M.; Sekita, S. Metabolome analysis ofEphedra plants with different contents of ephedrine alkaloids byusing UPLC-Q-TOF-MS. Planta Med., 2009, 75, 1356-1362.
    • (2009) Planta Med , vol.75 , pp. 1356-1362
    • Okada, T.1    Nakamura, Y.2    Kanaya, S.3    Takano, A.4    Malla, K.J.5    Nakane, T.6    Kitayama, M.7    Sekita, S.8
  • 65
    • 71649107637 scopus 로고    scopus 로고
    • Discrimination ofEphedra plants with diffuse reflectance FT-NIRS and multivariateanalysis
    • Fan, Q.; Wang, Y.; Sun, P.; Liu, S.; Li, Y. Discrimination ofEphedra plants with diffuse reflectance FT-NIRS and multivariateanalysis. Talanta, 2010, 80, 1245-1250.
    • (2010) Talanta , vol.80 , pp. 1245-1250
    • Fan, Q.1    Wang, Y.2    Sun, P.3    Liu, S.4    Li, Y.5
  • 66
    • 0036083139 scopus 로고    scopus 로고
    • Orthogonal projections to latent structures (O-PLS)
    • Trygg, J.; Wold, S. Orthogonal projections to latent structures (O-PLS). J. Chemom., 2002, 16, 119-128.
    • (2002) J. Chemom , vol.16 , pp. 119-128
    • Trygg, J.1    Wold, S.2
  • 67
    • 85007897102 scopus 로고
    • Studies onthe constituents of Umbelliferae plants. II. Isolation of the activeprinciples of Ligusticum root
    • Mitsuhashi, H.; Nagai, U.; Muramatsu, T; Tashiro, H. Studies onthe constituents of Umbelliferae plants. II. Isolation of the activeprinciples of Ligusticum root. Chem. Pharm. Bull., 1960, 8, 243-245.
    • (1960) Chem. Pharm. Bull , vol.8 , pp. 243-245
    • Mitsuhashi, H.1    Nagai, U.2    Muramatsu, T.3    Tashiro, H.4
  • 68
    • 14844339927 scopus 로고    scopus 로고
    • Assay of free ferulic acid and total ferulic acid for qualityassessment of Angelica sinensis
    • Lu, G.H.; Chan, K.; Leung, K.; Chan, C.L.; Zhao, Z.Z.; Jiang, Z.H.Assay of free ferulic acid and total ferulic acid for qualityassessment of Angelica sinensis. J. Chromatogr. A., 2005, 1068,209-219.
    • (2005) J. Chromatogr. A , vol.1068 , pp. 209-219
    • Lu, G.H.1    Chan, K.2    Leung, K.3    Chan, C.L.4    Zhao, Z.Z.5    Jiang, Z.H.6
  • 70
    • 47149112798 scopus 로고    scopus 로고
    • Metabolic profiling of Angelica acutiloba roots utilizing gaschromatography-time-of-flight-mass spectrometry for qualityassessment based on cultivation area and cultivar via multivariatepattern recognition
    • Tianniam, S.; Tarachiwin, L.; Bamba, T.; Kobayashi, A.; Fukusaki, E. Metabolic profiling of Angelica acutiloba roots utilizing gaschromatography-time-of-flight-mass spectrometry for qualityassessment based on cultivation area and cultivar via multivariatepattern recognition. J. Biosci. Bioeng., 2008, 105, 655-659.
    • (2008) J. Biosci. Bioeng , vol.105 , pp. 655-659
    • Tianniam, S.1    Tarachiwin, L.2    Bamba, T.3    Kobayashi, A.4    Fukusaki, E.5
  • 73
    • 57849146184 scopus 로고    scopus 로고
    • High-throughput technique for comprehensiveanalysis of Japanese green tea quality assessment using ultra-performance liquid chromatography with time-of-flight massspectrometry (UPLC/TOF MS)
    • Pongsuwan, W.; Bamba, T.; Harada, K.; Yonetani, T.; Kobayashi, A.; Fukusaki, E. High-throughput technique for comprehensiveanalysis of Japanese green tea quality assessment using ultra-performance liquid chromatography with time-of-flight massspectrometry (UPLC/TOF MS). J. Agric. Food. Chem., 2008, 56,10705-10708.
    • (2008) J. Agric. Food. Chem , vol.56 , pp. 10705-10708
    • Pongsuwan, W.1    Bamba, T.2    Harada, K.3    Yonetani, T.4    Kobayashi, A.5    Fukusaki, E.6
  • 74
    • 78649259053 scopus 로고    scopus 로고
    • 2nd eds; Harborne, J.B.; Baxter, H;Moss, G.P., Ed.; Taylor & Francis Ltd: London
    • In Phytochemical dictionary, 2nd eds; Harborne, J.B.; Baxter, H;Moss, G.P., Ed.; Taylor & Francis Ltd: London, 1999; pp. 737-738.
    • (1999) Phytochemical Dictionary , pp. 737-738
  • 75
    • 33847126285 scopus 로고    scopus 로고
    • Ultra-performance liquid chromatography/time-of-flight massspectrometry based metabolomics of raw and steamed Panaxnotoginseng
    • Chan, E.C.; Yap, S.L.; Lau, A.J.; Leow, P.C.; Toh, D.F.; Koh, H.L.Ultra-performance liquid chromatography/time-of-flight massspectrometry based metabolomics of raw and steamed Panaxnotoginseng. Rapid Commun. Mass Spectrom., 2007, 21, 519-528.
    • (2007) Rapid Commun. Mass Spectrom , vol.21 , pp. 519-528
    • Chan, E.C.1    Yap, S.L.2    Lau, A.J.3    Leow, P.C.4    Toh, D.F.5    Koh, H.L.6
  • 76
    • 33747019547 scopus 로고    scopus 로고
    • Centering, scaling, and transformations:Improving the biological information content of metabolomics data
    • van den Berg, R.A.; Hoefsloot, H.C.; Westerhuis, J.A.; Smilde, A.K.; van der Werf, M.J. Centering, scaling, and transformations:improving the biological information content of metabolomics data.BMC Genomics, 2006, 7, 142.
    • (2006) BMC Genomics , vol.7 , pp. 142
    • van den Berg, R.A.1    Hoefsloot, H.C.2    Westerhuis, J.A.3    Smilde, A.K.4    van der Werf, M.J.5
  • 77
    • 43249119417 scopus 로고    scopus 로고
    • Ultra-performance LC/TOF MS analysis ofmedicinal Panax herbs for metabolomic research
    • Xie, G.; Plumb, R.; Su, M.; Xu, Z.; Zhao, A.; Qiu, M.; Long, X.; Liu, Z.; Jia, W. Ultra-performance LC/TOF MS analysis ofmedicinal Panax herbs for metabolomic research. J. Sep. Sci.,2008, 31, 1015-1026.
    • (2008) J. Sep. Sci , vol.31 , pp. 1015-1026
    • Xie, G.1    Plumb, R.2    Su, M.3    Xu, Z.4    Zhao, A.5    Qiu, M.6    Long, X.7    Liu, Z.8    Jia, W.9
  • 81
    • 50649084834 scopus 로고    scopus 로고
    • Metabolic profiling of the Mexican anxiolyticand sedative plant Galphimia glauca using nuclear magneticresonance spectroscopy and multivariate data analysis
    • Cardoso-Taketa, A.T.; Pereda-Miranda, R.; Choi, Y.H.; Verpoorte, R.; Villarreal, M.L. Metabolic profiling of the Mexican anxiolyticand sedative plant Galphimia glauca using nuclear magneticresonance spectroscopy and multivariate data analysis. PlantaMed., 2008, 74, 1295-1301.
    • (2008) PlantaMed , vol.74 , pp. 1295-1301
    • Cardoso-Taketa, A.T.1    Pereda-Miranda, R.2    Choi, Y.H.3    Verpoorte, R.4    Villarreal, M.L.5
  • 83
    • 58749114381 scopus 로고    scopus 로고
    • New therapeutic aspects of flavones: The anticancerproperties of Scutellaria and its main active constituents Wogonin,Baicalein and Baicalin
    • Li-Weber, M. New therapeutic aspects of flavones: The anticancerproperties of Scutellaria and its main active constituents Wogonin,Baicalein and Baicalin. Cancer Treat. Rev., 2009, 35, 57-68.
    • (2009) Cancer Treat. Rev , vol.35 , pp. 57-68
    • Li-Weber, M.1
  • 84
    • 58849131579 scopus 로고    scopus 로고
    • 1H nuclear magnetic resonance (NMR)metabolomics approach combined with orthogonal projections tolatent structure-discriminant analysis as an efficient tool fordiscriminating between Korean and Chinese herbal medicines
    • 1H nuclear magnetic resonance (NMR)metabolomics approach combined with orthogonal projections tolatent structure-discriminant analysis as an efficient tool fordiscriminating between Korean and Chinese herbal medicines. J.Agric. Food. Chem., 2008, 56, 11589-11595.
    • (2008) J.Agric. Food. Chem , vol.56 , pp. 11589-11595
    • Kang, J.1    Choi, M.Y.2    Kang, S.3    Kwon, H.N.4    Wen, H.5    Lee, C.H.6    Park, M.7    Wiklund, S.8    Kim, H.J.9    Kwon, S.W.10    Park, S.11
  • 86
    • 33750055741 scopus 로고    scopus 로고
    • Clarification of pathway-specific inhibition by Fourier transformion cyclotron resonance/mass spectrometry-based metabolicphenotyping studies
    • Oikawa, A.; Nakamura, Y.; Ogura, T.; Kimura, A.; Suzuki, H.; Sakurai, N.; Shinbo, Y.; Shibata, D.; Kanaya, S.; Ohta, D.Clarification of pathway-specific inhibition by Fourier transformion cyclotron resonance/mass spectrometry-based metabolicphenotyping studies. Plant Physiol., 2006, 142, 398-413.
    • (2006) Plant Physiol , vol.142 , pp. 398-413
    • Oikawa, A.1    Nakamura, Y.2    Ogura, T.3    Kimura, A.4    Suzuki, H.5    Sakurai, N.6    Shinbo, Y.7    Shibata, D.8    Kanaya, S.9    Ohta, D.10
  • 87
    • 35648961364 scopus 로고    scopus 로고
    • Metabolic profiling usingFourier-transform ion-cyclotron-resonance mass spectrometry
    • Ohta, D.; Shibata, D.; Kanaya, S. Metabolic profiling usingFourier-transform ion-cyclotron-resonance mass spectrometry.Anal. Bioanal. Chem., 2007, 389, 1469-1475.
    • (2007) Anal. Bioanal. Chem , vol.389 , pp. 1469-1475
    • Ohta, D.1    Shibata, D.2    Kanaya, S.3
  • 91
    • 36248929401 scopus 로고    scopus 로고
    • Predicting state transitions in the transcriptome andmetabolome using a linear dynamical system model
    • Morioka, R.; Kanaya, S.; Hirai, M.; Yano, M.; Ogasawara, N.; Saito, K. Predicting state transitions in the transcriptome andmetabolome using a linear dynamical system model. BMCBioinformat., 2007, 8, 343.
    • (2007) BMCBioinformat , vol.8 , pp. 343
    • Morioka, R.1    Kanaya, S.2    Hirai, M.3    Yano, M.4    Ogasawara, N.5    Saito, K.6
  • 93
    • 33747130103 scopus 로고    scopus 로고
    • Break with tradition
    • Jayaraman, K.S. Break with tradition. Nature, 2006, 442, 342-343.
    • (2006) Nature , vol.442 , pp. 342-343
    • Jayaraman, K.S.1
  • 94
    • 56449085981 scopus 로고    scopus 로고
    • TCMGeneDIT: Adatabase for associated traditional Chinese medicine, gene anddisease information using text mining
    • Fang, Y.C.; Huang, H.C.; Chen, H.H.; Juan, H.F. TCMGeneDIT: adatabase for associated traditional Chinese medicine, gene anddisease information using text mining. BMC Complement. Altern.Med., 2008, 8, 58.
    • (2008) BMC Complement. Altern.Med , vol.8 , pp. 58
    • Fang, Y.C.1    Huang, H.C.2    Chen, H.H.3    Juan, H.F.4
  • 95
    • 73349101497 scopus 로고    scopus 로고
    • Analysis ofmetabolic variation and galanthamine content in Narcissus bulbs by1 H NMR, Phytochem
    • Lubbe, A.; Pomahacova, P.; Choi, Y.; Verpoorte, R. Analysis ofmetabolic variation and galanthamine content in Narcissus bulbs by1 H NMR, Phytochem. Anal., 2009, 21, 66-72.
    • (2009) Anal , vol.21 , pp. 66-72
    • Lubbe, A.1    Pomahacova, P.2    Choi, Y.3    Verpoorte, R.4
  • 96
    • 11144354344 scopus 로고    scopus 로고
    • Metabolomic strategy for the classification and quality control ofphytomedicine: A case study of chamomile flower (Matricariarecutita L.)
    • Wang, Y.; Tang, H.; Nicholson, J.K.; Hylands, P.J.; Sampson, J.; Whitcombe, I.; Stewart, C.G.; Caiger, S.; Oru, I.; Holmes, E.Metabolomic strategy for the classification and quality control ofphytomedicine: a case study of chamomile flower (Matricariarecutita L.). Planta Med., 2004, 70, 250-255.
    • (2004) Planta Med , vol.70 , pp. 250-255
    • Wang, Y.1    Tang, H.2    Nicholson, J.K.3    Hylands, P.J.4    Sampson, J.5    Whitcombe, I.6    Stewart, C.G.7    Caiger, S.8    Oru, I.9    Holmes, E.10
  • 97
    • 67651211781 scopus 로고    scopus 로고
    • Application of systems biologytechnology in research of traditional Chinese medicine
    • Li, P.; Yang, L.; Gong, Y. Application of systems biologytechnology in research of traditional Chinese medicine. J. Trad.Chinese Med., 2009, 29, 153-157.
    • (2009) J. Trad.Chinese Med , vol.29 , pp. 153-157
    • Li, P.1    Yang, L.2    Gong, Y.3
  • 98
    • 42749084886 scopus 로고    scopus 로고
    • Fingerprinting of complex mixtureswith the use of high performance liquid chromatography,inductively coupled plasma atomic emission spectroscopy andchemometrics
    • Ni, Y.; Peng, Y.; Kokot, S. Fingerprinting of complex mixtureswith the use of high performance liquid chromatography,inductively coupled plasma atomic emission spectroscopy andchemometrics. Anal. Chim. Acta, 2008, 616, 19-27.
    • (2008) Anal. Chim. Acta , vol.616 , pp. 19-27
    • Ni, Y.1    Peng, Y.2    Kokot, S.3
  • 99
    • 33947416094 scopus 로고    scopus 로고
    • Study oftraditional Chinese medicine volatile oils from differentgeographical origins by comprehensive two-dimensional gaschromatography-time-of-flight mass spectrometry (GC GC-TOFMS) in combination with multivariate analysis
    • Qiu, Y.; Lu, X.; Pang, T.; Zhu, S.; Kong, H.; Xu, G. Study oftraditional Chinese medicine volatile oils from differentgeographical origins by comprehensive two-dimensional gaschromatography-time-of-flight mass spectrometry (GC GC-TOFMS) in combination with multivariate analysis. J. Pharm.Biomed. Anal., 2007, 43, 1721-1727.
    • (2007) J. Pharm.Biomed. Anal , vol.43 , pp. 1721-1727
    • Qiu, Y.1    Lu, X.2    Pang, T.3    Zhu, S.4    Kong, H.5    Xu, G.6
  • 100
    • 33646402074 scopus 로고    scopus 로고
    • Tentative fingerprint-efficacy study of Houttuynia cordata injection in quality control oftraditional Chinese medicine
    • Lu, H.M.; Liang, Y.Z.; Wu, X.J.; Qiu, P. Tentative fingerprint-efficacy study of Houttuynia cordata injection in quality control oftraditional Chinese medicine. Chem. Pharm. Bull., 2006, 54, 725-730.
    • (2006) Chem. Pharm. Bull , vol.54 , pp. 725-730
    • Lu, H.M.1    Liang, Y.Z.2    Wu, X.J.3    Qiu, P.4
  • 101
    • 34248996862 scopus 로고    scopus 로고
    • Analysis ofberberine and total alkaloid content in Cortex Phellodendri by nearinfrared spectroscopy (NIRS) compared with high-performanceliquid chromatography coupled with ultra-visible spectrometricdetection
    • Chan, C-O.; Chu, C-C.; Mok, D.K-W.; Chau, F-T. Analysis ofberberine and total alkaloid content in Cortex Phellodendri by nearinfrared spectroscopy (NIRS) compared with high-performanceliquid chromatography coupled with ultra-visible spectrometricdetection. Anal. Chim. Acta, 2007, 592, 121-131.
    • (2007) Anal. Chim. Acta , vol.592 , pp. 121-131
    • Chan, C.-O.1    Chu, C.-C.2    Mok, D.K-W.3    Chau, F.-T.4
  • 103
    • 77958150812 scopus 로고    scopus 로고
    • Comparativemetabolomics approach coupled with cell-and gene-based assaysfor species classification and anti-inflammatory bioactivityvalidation of Echinacea plants
    • In Press
    • Hou, C.C.; Chen, C.H.; Yang, N.S.; Chen, Y.P.; Lo, C.P.; Wang, S.Y.; Tien, Y.J.; Tsai, P.W.; Shyur, L.F. Comparativemetabolomics approach coupled with cell-and gene-based assaysfor species classification and anti-inflammatory bioactivityvalidation of Echinacea plants. J. Nutr. Biochem., 2010, In Press.
    • (2010) J. Nutr. Biochem
    • Hou, C.C.1    Chen, C.H.2    Yang, N.S.3    Chen, Y.P.4    Lo, C.P.5    Wang, S.Y.6    Tien, Y.J.7    Tsai, P.W.8    Shyur, L.F.9
  • 104
    • 57849120057 scopus 로고    scopus 로고
    • Metabolic urinaryprofiling of alcohol hepatotoxicity and intervention effects of YinChen Hao Tang in rats using ultra-performance liquidchromatography/electrospray ionization quadruple time-of-flightmass spectrometry
    • Wang, X.; Lv, H.; Sun, H.; Liu, L.; Yang, B.; Sun, W.; Wang, P.; Zhou, D.; Zhao, L.; Dou, S.; Zhang, G.; Cao, H. Metabolic urinaryprofiling of alcohol hepatotoxicity and intervention effects of YinChen Hao Tang in rats using ultra-performance liquidchromatography/electrospray ionization quadruple time-of-flightmass spectrometry. J. Pharm. Biomed. Anal., 2008, 48, 1161-1168.
    • (2008) J. Pharm. Biomed. Anal , vol.48 , pp. 1161-1168
    • Wang, X.1    Lv, H.2    Sun, H.3    Liu, L.4    Yang, B.5    Sun, W.6    Wang, P.7    Zhou, D.8    Zhao, L.9    Dou, S.10    Zhang, G.11    Cao, H.12
  • 106
    • 29144486833 scopus 로고    scopus 로고
    • Metabonomic study on the biochemicalprofiles of a hydrocortisone-induced animal model
    • Chen, M.; Zhao, L.; Jia, W. Metabonomic study on the biochemicalprofiles of a hydrocortisone-induced animal model. J. ProteomeRes., 2005, 4, 2391-2396.
    • (2005) J. ProteomeRes , vol.4 , pp. 2391-2396
    • Chen, M.1    Zhao, L.2    Jia, W.3
  • 107
    • 37749042318 scopus 로고    scopus 로고
    • Fourier transformmid-infrared (MIR) and near-infrared (NIR) spectroscopy for rapidquality assessment of Chinese medicine preparation Honghua Oil
    • Wu, Y-W.; Sun, S-Q.; Zhou, Q.; Leung, H-W. Fourier transformmid-infrared (MIR) and near-infrared (NIR) spectroscopy for rapidquality assessment of Chinese medicine preparation Honghua Oil.J. Pharm. Biomed. Anal., 2008, 46, 498-504.
    • (2008) J. Pharm. Biomed. Anal , vol.46 , pp. 498-504
    • Wu, Y.-W.1    Sun, S.-Q.2    Zhou, Q.3    Leung, H.-W.4
  • 108
    • 33747144133 scopus 로고    scopus 로고
    • Chemometricclassification of traditional Chinese medicines by theirgeographical origins using near-infrared reflectance spectra
    • Xie, H.; Jiang, J.; Chen, Z.; Shen, G.; Yu, R. Chemometricclassification of traditional Chinese medicines by theirgeographical origins using near-infrared reflectance spectra. Anal.Sci., 2006, 22, 1111-1116.
    • (2006) Anal.Sci , vol.22 , pp. 1111-1116
    • Xie, H.1    Jiang, J.2    Chen, Z.3    Shen, G.4    Yu, R.5
  • 109
    • 62749109031 scopus 로고    scopus 로고
    • Acombined HPLC-PDA and HPLC-MS method for quantitative andqualitative analysis of 10 major constituents in the traditionalChinese medicine Zuo Gui Wan
    • Liang, X.; Zhang, X.; Dai, W.; Lv, Y.; Yan, S.; Zhang, W. Acombined HPLC-PDA and HPLC-MS method for quantitative andqualitative analysis of 10 major constituents in the traditionalChinese medicine Zuo Gui Wan. J. Pharm. Biomed. Anal., 2009,49, 931-936.
    • (2009) J. Pharm. Biomed. Anal , vol.49 , pp. 931-936
    • Liang, X.1    Zhang, X.2    Dai, W.3    Lv, Y.4    Yan, S.5    Zhang, W.6
  • 110
    • 46749115176 scopus 로고    scopus 로고
    • Prediction of cyclooxygenase inhibitory activity of curcumarhizome from chromatograms by multivariate analysis
    • Tanaka, K.; Kuba, Y.; Ina, A.; Watanabe, H.; Komatsu, K.Prediction of cyclooxygenase inhibitory activity of curcumarhizome from chromatograms by multivariate analysis. Chem.Pharm. Bull., 2008, 56, 936-940.
    • (2008) Chem.Pharm. Bull , vol.56 , pp. 936-940
    • Tanaka, K.1    Kuba, Y.2    Ina, A.3    Watanabe, H.4    Komatsu, K.5
  • 111


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.