Metabolic urinary profiling of alcohol hepatotoxicity and intervention effects of Yin Chen Hao Tang in rats using ultra-performance liquid chromatography/electrospray ionization quadruple time-of-flight mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis

Volumn 48, Issue 4, 2008, Pages 1161-1168

  Wang, Xijun ^a   Lv, Haitao ^a   Sun, Hui ^a   Liu, Lian ^a   Yang, Bo ^a   Sun, Wenjun ^a   Wang, Ping ^a   Zhou, Dixin ^a   Zhao, Li ^a   Dou, Shengshan ^a   Zhang, Guangmei ^c   Cao, Hongxin ^a,b  

^a HEILONGJIANG UNIVERSITY OF CHINESE MEDICINE   (China)

^b INSTITUTE OF CHINESE MATERIA MEDICA   (China)

^c HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Alcohol hepatotoxicity; Metabolic profiling; Ultra performance liquid chromatography electrospray ionization quadruple time of flight mass spectrometry; Yin Chen Hao Tan

Indexed keywords

ALCOHOL; CERAMIDE; CHINESE DRUG; SPHINGOMYELIN; UNCLASSIFIED DRUG; YIN CHEN HAO TANG;

ANALYTIC METHOD; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHINA; CHINESE MEDICINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ELECTROSPRAY IONIZATION QUADRUPOLE TIME OF FLIGHT MASS SPECTROMETRY; ELECTROSPRAY MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; LIVER TOXICITY; MALE; METABOLISM; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; URINE LEVEL;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG TOXICITY; DRUGS, CHINESE HERBAL; ETHANOL; HEPATOCYTES; MALE; MEDICINE, CHINESE TRADITIONAL; METABOLOME; RANDOM ALLOCATION; RATS; RATS, WISTAR; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; URINALYSIS; URINARY TRACT;

EID: 57849120057     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2008.07.028     Document Type: Article

References (29)

1. Griffin J.L. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 3261 (2006) 147-161
2. Nicholson J.K., Holmes E., and Wilson I.D. Nat. Rev. Microbiol. 3 (2005) 431-438
3. Bijlsma S., Bobeldijk I., Verheij E.R., Ramaker R., Kochhar S., Mcdonald I.A., Ommen B.V., and Smilde A.K. Anal. Chem. 78 (2006) 567-574
4. Nicholson J.K., Connelly J., Lindon J.C., and Holmes E. Nat. Rev. Drug Discov. 1 (2002) 153-161
5. Nicholson J.K., and Wilson I.D. Nat. Rev. Drug Discov. 8 (2003) 668-676
6. Major H.J., Williams R., Wilson A.J., and Wilson I.D. Rapid Commun. Mass Spectrom. 20 (2006) 3295-3302
7. Fancy S.A., Beckonert O., Darbon G., Yabsley W., Walley R., Baker D., Perkins G.L., Pullen F.S., and Rumpel K. Rapid Commun. Mass Spectrom. 20 (2006) 2271-2280
8. Sangster T.P., Wingate J.E., Burton L., Teichert F., and Wilson I.D. Rapid Commun. Mass Spectrom. 21 (2007) 2965-2970
9. Granger J.H., Williams R., Lenz E.M., Plumb R.S., Stumpf C.L., and Wilson I.D. Rapid Commun. Mass Spectrom. 21 (2007) 2039-2045
10. In: Robertson D., Lindon J.C., Nicholson J.K., and Holmes E. (Eds). Metabonomics in Toxicity Assessment (2005), CRC Press, Boca Raton
11. Diehl A.M. Alcohol 27 (2002) 7-11
12. Esteban R. Semin. Liver Dis. 22 (2002) 1-6
13. Walker M.P., Appleby T.C., Zhong W., Lau J.Y., and Hong Z. Antivir. Chem. Chemother. 14 (2003) 1-21
14. Jarvelainen H.A., Fang C., Ingelman-Sundberg M., Lukkari T.A., Sippel H., and Lindros K.O. J. Hepatol. 32 (2000) 900-910
15. Stewart S., Jones D., and Day C.P. Trends Mol. Med. 7 (2001) 408-413
16. Tsukamoto H., Lin M., Ohata M., Giulivi C., French S.W., and Brittenham G. Am. J. Physiol. 277 (1999) G1240-G1250
17. Tilg H., and Diehl A.M. N. Engl. J. Med. 343 (2000) 1467-1476
18. Arteel G.E. Gastroenterology 124 (2003) 778-790
19. Itoh T., Shibahara N., Mantani N., Tahara E., Shimada Y., and Terasawa K. J. Trad. Med. 14 (1997) 204-210
20. Onji M., Kikuchi T., Michitaka K., Yamashita K., and Ohta Y. J. Med. Pharm. Soc. WakanYaku. 7 (1990) 161-167
21. Inao M., Mochida S., Matsui A., Eguchi Y., Yulutuz Y., Wang Y.H., Naiki K., Kakinuma T., Fujimori K., Nagoshi S., and Fujiwara K. J. Hepatol. 41 (2004) 584-591
22. Imanishi Y., Maeda N., Otogawa K., Seki S., Matsui H., Kawada N., and Arakawa T. J. Hepatol. 41 (2004) 242-250
23. Zhang Z.J. Shanghanlun (2005), People Hygiene Publisher, Beijing p. 8
24. Siskind L.J., Feinstein L., Yu T.X., Davis J.S., Jones D., Zuckerman J.E., Tan W.Z., Hill R.B., Hardwick J.M., and Colombini M. J. Biol. Chem. 283 (2008) 6622-6630
25. Chen J., Nikolova-Karakashian M., MerrillJr A.H., and Morgan E.T. J. Biol. Chem. 270 (1995) 25233-25238
26. Deaciuc I.V., Nikolova-Karakashian M., Fortunato F., Lee E.Y., Hill D.B., and Mc Clain C.J. Alcohol Clin. Exp. Res. 24 (2000) 1557-1565
27. Jones B.E., Lo C.R., Srinivasan A., Valentino K.L., and Czaja M.J. Hepatology 30 (1999) 215-222
28. Batey R.G., and Wang J. Front. Biosci. 7 (2002) d1662-d1675
29. DeVito W.J., Xhaja K., and Stone S. Alcohol. 21 (2000) 63-71