-
1
-
-
0033004248
-
Differences in electron transport potential, antioxidant defenses, and oxidant generation in young and senescent fetal lung fibroblasts (WI-38)
-
Allen RG, Tresini M, Keogh BP, Doggett DL, Cristofalo VJ (1999) Differences in electron transport potential, antioxidant defenses, and oxidant generation in young and senescent fetal lung fibroblasts (WI-38). J. Cell. Physiol. 180, 114-122.
-
(1999)
J. Cell. Physiol.
, vol.180
, pp. 114-122
-
-
Allen, R.G.1
Tresini, M.2
Keogh, B.P.3
Doggett, D.L.4
Cristofalo, V.J.5
-
2
-
-
34250355048
-
Mitochondrial genetic background modifies breast cancer risk
-
Bai RK, Leal SM, Covarrubias D, Liu A, Wong LJ (2007) Mitochondrial genetic background modifies breast cancer risk. Cancer Res. 67, 4687-4694.
-
(2007)
Cancer Res
, vol.67
, pp. 4687-4694
-
-
Bai, R.K.1
Leal, S.M.2
Covarrubias, D.3
Liu, A.4
Wong, L.J.5
-
3
-
-
47849117411
-
New model of health promotion and disease prevention for the 21st century
-
Butler RN, Miller RA, Perry D, Carnes BA, Williams TF, Cassel C, Brody J, Bernard MA, Partridge L, Kirkwood T, Martin GM, Olshansky SJ (2008) New model of health promotion and disease prevention for the 21st century. BMJ. 337, a399.
-
(2008)
BMJ
, vol.337
-
-
Butler, R.N.1
Miller, R.A.2
Perry, D.3
Carnes, B.A.4
Williams, T.F.5
Cassel, C.6
Brody, J.7
Bernard, M.A.8
Partridge, L.9
Kirkwood, T.10
Martin, G.M.11
Olshansky, S.J.12
-
4
-
-
84891713034
-
Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor
-
Coppe JP, Patil CK, Rodier F, Sun Y, Munoz DP, Goldstein J et al. (2008) Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS Biol. 6, 2853-2868.
-
(2008)
PLoS Biol
, vol.6
, pp. 2853-2868
-
-
Coppe, J.P.1
Patil, C.K.2
Rodier, F.3
Sun, Y.4
Munoz, D.P.5
Goldstein, J.6
-
5
-
-
67649204729
-
Overexpression of catalase targeted to mitochondria attenuates murine cardiac aging
-
Dai DF, Santana LF, Vermulst M, Tomazela DM, Emond MJ, MacCoss MJ et al. (2009) Overexpression of catalase targeted to mitochondria attenuates murine cardiac aging. Circulation 119, 2789-2797.
-
(2009)
Circulation
, vol.119
, pp. 2789-2797
-
-
Dai, D.F.1
Santana, L.F.2
Vermulst, M.3
Tomazela, D.M.4
Emond, M.J.5
MacCoss, M.J.6
-
6
-
-
3042781117
-
Senescence-associated changes in respiration and oxidative phosphorylation in primary human fibroblasts
-
Hutter E, Renner K, Pfister G, Stockl P, Jansen-Durr P, Gnaiger E (2004) Senescence-associated changes in respiration and oxidative phosphorylation in primary human fibroblasts. Biochem. J. 380 (Pt 3), 919-928.
-
(2004)
Biochem. J.
, vol.380
, Issue.PT 3
, pp. 919-928
-
-
Hutter, E.1
Renner, K.2
Pfister, G.3
Stockl, P.4
Jansen-Durr, P.5
Gnaiger, E.6
-
7
-
-
43249112094
-
ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis
-
Ishikawa K, Takenaga K, Akimoto M, Koshikawa N, Yamaguchi A, Imanishi H et al. (2008) ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis. Science 320, 661-664.
-
(2008)
Science
, vol.320
, pp. 661-664
-
-
Ishikawa, K.1
Takenaga, K.2
Akimoto, M.3
Koshikawa, N.4
Yamaguchi, A.5
Imanishi, H.6
-
8
-
-
33645526144
-
Cancer statistics 2006
-
Jemal A, Siegel R, Ward E, Murray T, Xu J, Smigal C et al. (2006) Cancer statistics, 2006. CA Cancer J. Clin. 56, 106-130.
-
(2006)
CA Cancer J. Clin.
, vol.56
, pp. 106-130
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Murray, T.4
Xu, J.5
Smigal, C.6
-
9
-
-
0036420161
-
Increase in mitochondrial mass in human fibroblasts under oxidative stress and during replicative cell senescence
-
Lee HC, Yin PH, Chi CW, Wei YH (2002) Increase in mitochondrial mass in human fibroblasts under oxidative stress and during replicative cell senescence. J. Biomed. Sci. 9 (6 Pt 1), 517.
-
(2002)
J. Biomed. Sci.
, vol.9
, Issue.6 PT 1
, pp. 517
-
-
Lee, H.C.1
Yin, P.H.2
Chi, C.W.3
Wei, Y.H.4
-
10
-
-
0142244181
-
Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancermodel provides a reliable model for human diseases
-
Lin EY, Jones JG, Li P, Zhu L, Whitney KD, Muller WJ, Pollard JW (2003) Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancermodel provides a reliable model for human diseases. Am. J. Pathol. 163, 2113-2126.
-
(2003)
Am. J. Pathol.
, vol.163
, pp. 2113-2126
-
-
Lin, E.Y.1
Jones, J.G.2
Li, P.3
Zhu, L.4
Whitney, K.D.5
Muller, W.J.6
Pollard, J.W.7
-
11
-
-
36549025804
-
Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages
-
Lin EY, Li JF, Bricard G, Wang W, Deng Y, Sellers R, Porcelli SA, Pollard JW (2007) Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages. Mol. Oncol. 1, 288-302.
-
(2007)
Mol. Oncol.
, vol.1
, pp. 288-302
-
-
Lin, E.Y.1
Li, J.F.2
Bricard, G.3
Wang, W.4
Deng, Y.5
Sellers, R.6
Porcelli, S.A.7
Pollard, J.W.8
-
12
-
-
20044383911
-
Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial
-
Lonn E, Bosch J, Yusuf S, Sheridan P, Pogue J, Arnold JM et al. (2005) Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial. JAMA 293, 1338-1347.
-
(2005)
JAMA
, vol.293
, pp. 1338-1347
-
-
Lonn, E.1
Bosch, J.2
Yusuf, S.3
Sheridan, P.4
Pogue, J.5
Arnold, J.M.6
-
13
-
-
33847071146
-
Targeting antioxidants to mitochondria by conjugation to lipophilic cations
-
Murphy MP, Smith RA (2007) Targeting antioxidants to mitochondria by conjugation to lipophilic cations. Annu. Rev. Pharmacol. Toxicol. 47, 629-656.
-
(2007)
Annu. Rev. Pharmacol. Toxicol.
, vol.47
, pp. 629-656
-
-
Murphy, M.P.1
Smith, R.A.2
-
14
-
-
0033826520
-
Role for mitochondrial oxidants as regulators of cellular metabolism
-
Nemoto S, Takeda K, Yu ZX, Ferrans VJ, Finkel T (2000) Role for mitochondrial oxidants as regulators of cellular metabolism. Mol. Cell. Biol. 20, 7311-7318.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 7311-7318
-
-
Nemoto, S.1
Takeda, K.2
Yu, Z.X.3
Ferrans, V.J.4
Finkel, T.5
-
15
-
-
21244431867
-
Mitochondria, telomeres and cell senescence
-
Passos JF, von Zglinicki T (2005) Mitochondria, telomeres and cell senescence. Exp. Gerontol. 40, 466-472.
-
(2005)
Exp. Gerontol.
, vol.40
, pp. 466-472
-
-
Passos, J.F.1
von Zglinicki, T.2
-
16
-
-
38049057905
-
DNA damage in telomeres and mitochondria during cellular senescence: is there a connection?
-
Passos JF, Saretzki G, von Zglinicki T (2007) DNA damage in telomeres and mitochondria during cellular senescence: is there a connection? Nucleic Acids Res. 35, 7505-7513.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 7505-7513
-
-
Passos, J.F.1
Saretzki, G.2
von Zglinicki, T.3
-
17
-
-
69949091182
-
Is the oxidative stress theory of aging dead?
-
1005-14. Epub 2009 June
-
Pérez VI, Bokov A, Van Remmen H, Mele J, Ran Q, Ikeno Y, Richardson A (2009) Is the oxidative stress theory of aging dead? Biochim. Biophys. Acta 1790, 1005-14. Epub 2009 June 11.
-
(1790)
Biochim. Biophys. Acta
, pp. 11
-
-
Pérez, V.I.1
Bokov, A.2
Van Remmen, H.3
Mele, J.4
Ran, Q.5
Ikeno, Y.6
Richardson, A.7
-
18
-
-
65549144609
-
Mitochondria as targets for cancer therapy
-
Ralph SJ, Neuzil J (2009) Mitochondria as targets for cancer therapy. Mol. Nutr. Food Res. 53, 9-28.
-
(2009)
Mol. Nutr. Food Res.
, vol.53
, pp. 9-28
-
-
Ralph, S.J.1
Neuzil, J.2
-
19
-
-
21144434217
-
Extension of murine life span by overexpression of catalase targeted to mitochondria
-
Schriner SE, Linford NJ, Martin GM, Treuting P, Ogburn CE, Ladiges WC, Emond M, Wallace D, Rabinovitch P (2005) Extension of murine life span by overexpression of catalase targeted to mitochondria. Science 308, 1909-1911.
-
(2005)
Science
, vol.308
, pp. 1909-1911
-
-
Schriner, S.E.1
Linford, N.J.2
Martin, G.M.3
Treuting, P.4
Ogburn, C.E.5
Ladiges, W.C.6
Emond, M.7
Wallace, D.8
Rabinovitch, P.9
-
20
-
-
0035993208
-
Tumor-associated macrophages: a molecular perspective
-
Sica A, Saccani A, Mantovani A (2002) Tumor-associated macrophages: a molecular perspective. Int. Immunopharmacol. 2, 1045-1054.
-
(2002)
Int. Immunopharmacol.
, vol.2
, pp. 1045-1054
-
-
Sica, A.1
Saccani, A.2
Mantovani, A.3
-
21
-
-
0033674181
-
Protein oxidation and degradation during cellular senescence of human BJ fibroblasts: part II-aging of nondividing cells
-
Sitte N, Merker K, Von Zglinicki T, Davies KJ, Grune T (2000) Protein oxidation and degradation during cellular senescence of human BJ fibroblasts: part II-aging of nondividing cells. FASEB J. 14, 2503-2510.
-
(2000)
FASEB J
, vol.14
, pp. 2503-2510
-
-
Sitte, N.1
Merker, K.2
Von Zglinicki, T.3
Davies, K.J.4
Grune, T.5
-
22
-
-
0035092972
-
Lipofuscin accumulation in proliferating fibroblasts in vitro: an indicator of oxidative stress
-
Sitte N, Merker K, Grune T, von Zglinicki T (2001) Lipofuscin accumulation in proliferating fibroblasts in vitro: an indicator of oxidative stress. Exp. Gerontol. 36, 475-486.
-
(2001)
Exp. Gerontol.
, vol.36
, pp. 475-486
-
-
Sitte, N.1
Merker, K.2
Grune, T.3
von Zglinicki, T.4
-
23
-
-
38449092832
-
Transcriptional control of mitochondrial energy metabolism through the PGC1 coactivators
-
Spiegelman BM (2007) Transcriptional control of mitochondrial energy metabolism through the PGC1 coactivators. Novartis Found. Symp. 287, 60-63.
-
(2007)
Novartis Found. Symp.
, vol.287
, pp. 60-63
-
-
Spiegelman, B.M.1
-
24
-
-
53349153165
-
Reduction of age-associated pathology in old mice by overexpression of catalase in mitochondria
-
Treuting PM, Linford NJ, Knoblaugh SE, Emond MJ, Morton JF, Martin GM, Ladiges WC (2008) Reduction of age-associated pathology in old mice by overexpression of catalase in mitochondria. J. Gerontol. A Biol. Sci. Med. Sci. 63, 813-822.
-
(2008)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.63
, pp. 813-822
-
-
Treuting, P.M.1
Linford, N.J.2
Knoblaugh, S.E.3
Emond, M.J.4
Morton, J.F.5
Martin, G.M.6
Ladiges, W.C.7
-
25
-
-
9444258632
-
Role of oxygen radicals in DNA damage and cancer incidence
-
Valko M, Izakovic M, Mazur M, Rhodes CJ, Telser J (2004) Role of oxygen radicals in DNA damage and cancer incidence. Mol. Cell. Biochem. 266, 37-56.
-
(2004)
Mol. Cell. Biochem.
, vol.266
, pp. 37-56
-
-
Valko, M.1
Izakovic, M.2
Mazur, M.3
Rhodes, C.J.4
Telser, J.5
-
26
-
-
23844558266
-
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine
-
Wallace DC (2005) A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu. Rev. Genet. 39, 359-407.
-
(2005)
Annu. Rev. Genet.
, vol.39
, pp. 359-407
-
-
Wallace, D.C.1
-
27
-
-
0036294999
-
A role for mitochondria as potential regulators of cellular life span
-
Xu D, Finkel T (2002) A role for mitochondria as potential regulators of cellular life span. Biochem. Biophys. Res. Commun. 294, 245-248.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.294
, pp. 245-248
-
-
Xu, D.1
Finkel, T.2
-
28
-
-
0346256784
-
Metabolic analysis of senescent human fibroblasts reveals a role for AMP in cellular senescence
-
Zwerschke W, Mazurek S, Stockl P, Hutter E, Eigenbrodt E, Jansen-Durr P (2003) Metabolic analysis of senescent human fibroblasts reveals a role for AMP in cellular senescence. Biochem. J. 376 (Pt 2), 403-411.
-
(2003)
Biochem. J.
, vol.376
, Issue.PART 2
, pp. 403-411
-
-
Zwerschke, W.1
Mazurek, S.2
Stockl, P.3
Hutter, E.4
Eigenbrodt, E.5
Jansen-Durr, P.6
|