A novel domain mediates insulin-induced proteasomal degradation of Insulin Receptor Substrate 1 (IRS-1)

Molecular Endocrinology

Volumn 24, Issue 11, 2010, Pages 2179-2192

  Boura Halfon, Sigalit ^a   Shuster Meiseles, Timor ^a   Beck, Avital ^a   Petrovich, Katia ^a   Gurevitch, Diana ^a   Ronen, Denise ^a   Zick, Yehiel ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; PHOSPHOTRANSFERASE; PROTEASOME; PROTEIN KINASE B; SERINE; THREONINE;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CHO CELL; CONTROLLED STUDY; ENZYME ACTIVATION; FISH; GENE DELETION; GENETIC TRANSFECTION; GLYCOGEN SYNTHESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; RAT; SIGNAL TRANSDUCTION; UBIQUITINATION;

ANIMALS; APOPTOSIS; CHO CELLS; CRICETINAE; CRICETULUS; CYTOPROTECTION; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; MICE; MUTANT PROTEINS; PHOSPHORYLATION; PHOSPHOSERINE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-MDM2; RATS; SEQUENCE DELETION; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; UBIQUITINATION;

MAMMALIA; RATTUS;

EID: 78049344815     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2010-0072     Document Type: Article

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