Mechanism of microRNA-target interaction: Molecular dynamics simulations and thermodynamics analysis

PLoS Computational Biology

Volumn 6, Issue 7, 2010, Pages 5-

  Wang, Yonghua ^a   Li, Yan ^b   Ma, Zhi ^a   Yang, Wei ^a   Ai, Chunzhi ^c  

^a NORTHWEST A F UNIVERSITY   (China)

^b DALIAN UNIVERSITY OF TECHNOLOGY   (China)

^c DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CATALYST ACTIVITY; METAL IONS; METALS; MOLECULAR DYNAMICS; PRINCIPAL COMPONENT ANALYSIS; SUBSTRATES; THERMOANALYSIS; THERMODYNAMIC PROPERTIES;

ARGONAUTE PROTEINS; CONFORMATIONAL CHANGE; CORRELATION ANALYSIS; DYNAMIC SIMULATION ANALYSIS; GLOBAL DYNAMICS; MOLECULAR MECHANISM; PRINCIPAL-COMPONENT ANALYSIS; RNA INTERFERENCE; SMALL INTERFERING RNA; THERMO DYNAMIC ANALYSIS;

RNA;

ARGONAUTE PROTEIN; MAGNESIUM ION; MESSENGER RNA; MICRORNA; SMALL INTERFERING RNA; BACTERIAL PROTEIN; MAGNESIUM; PROTEIN;

ARTICLE; BASE PAIRING; BINDING AFFINITY; CONTROLLED STUDY; ENZYME ACTIVITY; HYDROGEN BOND; MOLECULAR DYNAMICS; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN TARGETING; RNA BINDING; RNA CLEAVAGE; RNA INTERFERENCE; STRUCTURE ANALYSIS; THERMODYNAMICS; CHEMISTRY; METABOLISM; POISSON DISTRIBUTION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; THERMUS THERMOPHILUS;

BACTERIAL PROTEINS; MAGNESIUM; MICRORNAS; MOLECULAR DYNAMICS SIMULATION; POISSON DISTRIBUTION; PRINCIPAL COMPONENT ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PROTEINS; THERMODYNAMICS; THERMUS THERMOPHILUS;

EID: 78049314237     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000866     Document Type: Article

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