-
1
-
-
0028174061
-
Function and activation of NF-kappa B in the immune system
-
Baeuerle P.A., and Henkel T. Function and activation of NF-kappa B in the immune system. Annu. Rev. Immunol. 12 (1994) 141-179
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 141-179
-
-
Baeuerle, P.A.1
Henkel, T.2
-
2
-
-
0029874138
-
The NF-kappa B and I kappa B proteins: new discoveries and insights
-
Baldwin Jr. A.S. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu. Rev. Immunol. 14 (1996) 649-683
-
(1996)
Annu. Rev. Immunol.
, vol.14
, pp. 649-683
-
-
Baldwin Jr., A.S.1
-
3
-
-
49349094024
-
Regulation of the RelA (p65) transactivation domain
-
O'Shea J.M., and Perkins N.D. Regulation of the RelA (p65) transactivation domain. Biochem. Soc. Trans. 36 (2008) 603-608
-
(2008)
Biochem. Soc. Trans.
, vol.36
, pp. 603-608
-
-
O'Shea, J.M.1
Perkins, N.D.2
-
4
-
-
0032039076
-
Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300
-
Zhong H., Voll R.E., and Ghosh S. Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300. Mol. Cell 1 (1998) 661-671
-
(1998)
Mol. Cell
, vol.1
, pp. 661-671
-
-
Zhong, H.1
Voll, R.E.2
Ghosh, S.3
-
5
-
-
0037462880
-
Phosphorylation of serine 276 is essential for p65 NF-kappaB subunit-dependent cellular responses
-
Okazaki T., Sakon S., Sasazuki T., Sakurai H., Doi T., Yagita H., Okumura K., and Nakano H. Phosphorylation of serine 276 is essential for p65 NF-kappaB subunit-dependent cellular responses. Biochem. Biophys. Res. Commun. 300 (2003) 807-812
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.300
, pp. 807-812
-
-
Okazaki, T.1
Sakon, S.2
Sasazuki, T.3
Sakurai, H.4
Doi, T.5
Yagita, H.6
Okumura, K.7
Nakano, H.8
-
6
-
-
0037451357
-
Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)
-
Vermeulen L., De Wilde G., Van Damme P., Vanden Berghe W., and Haegeman G. Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1). EMBO J. 22 (2003) 1313-1324
-
(2003)
EMBO J.
, vol.22
, pp. 1313-1324
-
-
Vermeulen, L.1
De Wilde, G.2
Van Damme, P.3
Vanden Berghe, W.4
Haegeman, G.5
-
7
-
-
12844286907
-
Cis-acting, element-specific transcriptional activity of differentially phosphorylated nuclear factor-kappa B
-
Anrather J., Racchumi G., and Iadecola C. Cis-acting, element-specific transcriptional activity of differentially phosphorylated nuclear factor-kappa B. J. Biol. Chem. 1 (2005) 244-252
-
(2005)
J. Biol. Chem.
, vol.1
, pp. 244-252
-
-
Anrather, J.1
Racchumi, G.2
Iadecola, C.3
-
8
-
-
0037414809
-
The transcriptional coactivator CREB-binding protein cooperates with STAT1 and NF-kappa B for synergistic transcriptional activation of the CXC ligand 9/monokine induced by interferon-gamma gene
-
Hiroi M., and Ohmori Y. The transcriptional coactivator CREB-binding protein cooperates with STAT1 and NF-kappa B for synergistic transcriptional activation of the CXC ligand 9/monokine induced by interferon-gamma gene. J. Biol. Chem. 278 (2003) 651-660
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 651-660
-
-
Hiroi, M.1
Ohmori, Y.2
-
9
-
-
0032771498
-
Transcriptional activation by NF-kappaB requires multiple coactivators
-
Sheppard K.A., Rose D.W., Haque Z.K., Kurokawa R., McInerney E., Westin S., Thanos D., Rosenfeld M.G., Glass C.K., and Collins T. Transcriptional activation by NF-kappaB requires multiple coactivators. Mol. Cell. Biol. 19 (1999) 6367-6378
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 6367-6378
-
-
Sheppard, K.A.1
Rose, D.W.2
Haque, Z.K.3
Kurokawa, R.4
McInerney, E.5
Westin, S.6
Thanos, D.7
Rosenfeld, M.G.8
Glass, C.K.9
Collins, T.10
-
10
-
-
0030914691
-
CREB-binding protein/p300 are transcriptional coactivators of p65
-
Gerritsen M.E., Williams A.J., Neish A.S., Moore S., Shi Y., and Collins T. CREB-binding protein/p300 are transcriptional coactivators of p65. Proc. Natl. Acad. Sci. USA 94 (1997) 2927-2932
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 2927-2932
-
-
Gerritsen, M.E.1
Williams, A.J.2
Neish, A.S.3
Moore, S.4
Shi, Y.5
Collins, T.6
-
11
-
-
0033527448
-
The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter
-
Vanden Berghe W., De Bosscher K., Boone E., Plaisance S., and Haegeman G. The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter. J. Biol. Chem. 274 (1999) 32091-32098
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 32091-32098
-
-
Vanden Berghe, W.1
De Bosscher, K.2
Boone, E.3
Plaisance, S.4
Haegeman, G.5
-
12
-
-
0033579490
-
Chromium(VI) inhibits the transcriptional activity of nuclear factor-kappaB by decreasing the interaction of p65 with cAMP-responsive element-binding protein-binding protein
-
Shumilla J.A., Broderick R.J., Wang Y., and Barchowsky A. Chromium(VI) inhibits the transcriptional activity of nuclear factor-kappaB by decreasing the interaction of p65 with cAMP-responsive element-binding protein-binding protein. J. Biol. Chem. 274 (1999) 36207-36212
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 36207-36212
-
-
Shumilla, J.A.1
Broderick, R.J.2
Wang, Y.3
Barchowsky, A.4
-
13
-
-
0034644719
-
NF-kappa B inhibits glucocorticoid and cAMP-mediated expression of the phosphoenolpyruvate carboxykinase gene
-
Waltner-Law M., Daniels M.C., Sutherland C., and Granner D.K. NF-kappa B inhibits glucocorticoid and cAMP-mediated expression of the phosphoenolpyruvate carboxykinase gene. J. Biol. Chem. 275 (2000) 31847-31856
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 31847-31856
-
-
Waltner-Law, M.1
Daniels, M.C.2
Sutherland, C.3
Granner, D.K.4
-
14
-
-
44349176408
-
RelA ser276 phosphorylation is required for activation of a subset of NF-κB-dependent genes by recruiting cyclin-dependent kinase 9/cyclin T1 complexes
-
Nowak D.E., Tian B., Jamaluddin M., Boldogh I., Vergara L.A., Choudhary S., and Brasier A.R. RelA ser276 phosphorylation is required for activation of a subset of NF-κB-dependent genes by recruiting cyclin-dependent kinase 9/cyclin T1 complexes. Mol. Cell. Biol. 28 (2008) 3623-3638
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 3623-3638
-
-
Nowak, D.E.1
Tian, B.2
Jamaluddin, M.3
Boldogh, I.4
Vergara, L.A.5
Choudhary, S.6
Brasier, A.R.7
-
15
-
-
0032478271
-
A simplified system for generating recombinant adenoviruses
-
He T.C., Zhou S., da Costa L.T., Yu J., Kinzler K.W., and Vogelstein B.A. A simplified system for generating recombinant adenoviruses. Proc. Natl. Acad. Sci. USA 95 (1998) 2509-2514
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 2509-2514
-
-
He, T.C.1
Zhou, S.2
da Costa, L.T.3
Yu, J.4
Kinzler, K.W.5
Vogelstein, B.A.6
-
16
-
-
0033582455
-
Inhibition of DNA synthesis by a farnesyltransferase inhibitor involves inhibition of the p70(s6k) pathway
-
Law B.K., Norgaard P., Gnudi L., Kahn B.B., Poulson H.S., and Moses H.L. Inhibition of DNA synthesis by a farnesyltransferase inhibitor involves inhibition of the p70(s6k) pathway. J. Biol. Chem. 274 (1999) 4743-4748
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 4743-4748
-
-
Law, B.K.1
Norgaard, P.2
Gnudi, L.3
Kahn, B.B.4
Poulson, H.S.5
Moses, H.L.6
-
17
-
-
0036888908
-
Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells
-
Law B.K., Chytil A., Dumont N., Hamilton E.G., Waltner-Law M.E., Aakre M.E., Covington C., and Moses H.L. Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells. Mol. Cell. Biol. 22 (2002) 8184-8198
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 8184-8198
-
-
Law, B.K.1
Chytil, A.2
Dumont, N.3
Hamilton, E.G.4
Waltner-Law, M.E.5
Aakre, M.E.6
Covington, C.7
Moses, H.L.8
-
18
-
-
0028988585
-
Inhibitors of mammalian G1 cyclin-dependent kinases
-
Sherr C.J., and Roberts J.M. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev. 9 (1995) 1149-1163
-
(1995)
Genes Dev.
, vol.9
, pp. 1149-1163
-
-
Sherr, C.J.1
Roberts, J.M.2
-
19
-
-
0033564697
-
CDK inhibitors: positive and negative regulators of G1-phase progression
-
Sherr C.J., and Roberts J.M. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 13 (1999) 1501-1512
-
(1999)
Genes Dev.
, vol.13
, pp. 1501-1512
-
-
Sherr, C.J.1
Roberts, J.M.2
-
20
-
-
0032491485
-
Activation of nuclear factor-kappaB-dependent transcription by tumor necrosis factor-alpha is mediated through phosphorylation of RelA/p65 on serine 529
-
Wang D., and Baldwin Jr. A.S. Activation of nuclear factor-kappaB-dependent transcription by tumor necrosis factor-alpha is mediated through phosphorylation of RelA/p65 on serine 529. J. Biol. Chem. 273 (1998) 29411-29416
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 29411-29416
-
-
Wang, D.1
Baldwin Jr., A.S.2
-
21
-
-
0032589462
-
IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain
-
Sakurai H., Chiba H., Miyoshi H., Sugita T., and Toriumi W. IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain. J. Biol. Chem. 274 (1999) 30353-30356
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 30353-30356
-
-
Sakurai, H.1
Chiba, H.2
Miyoshi, H.3
Sugita, T.4
Toriumi, W.5
-
22
-
-
0141703513
-
Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway
-
Sakurai H., Suzuki S., Kawasaki N., Nakano H., Okazaki T., Chino A., Doi T., and Saiki I. Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway. J. Biol. Chem. 278 (2003) 36916-36923
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 36916-36923
-
-
Sakurai, H.1
Suzuki, S.2
Kawasaki, N.3
Nakano, H.4
Okazaki, T.5
Chino, A.6
Doi, T.7
Saiki, I.8
-
23
-
-
0034693133
-
Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II
-
Wang D., Westerheide S.D., Hanson J.L., and Baldwin Jr. A.S. Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II. J. Biol. Chem. 275 (2000) 32592-32597
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 32592-32597
-
-
Wang, D.1
Westerheide, S.D.2
Hanson, J.L.3
Baldwin Jr., A.S.4
-
24
-
-
0037428385
-
The NF-kappa B activation in lymphotoxin beta receptor signaling depends on the phosphorylation of p65 at serine 536
-
Jiang X., Takahashi N., Matsui N., Tetsuka T., and Okamoto T. The NF-kappa B activation in lymphotoxin beta receptor signaling depends on the phosphorylation of p65 at serine 536. J. Biol. Chem. 278 (2003) 919-926
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 919-926
-
-
Jiang, X.1
Takahashi, N.2
Matsui, N.3
Tetsuka, T.4
Okamoto, T.5
-
25
-
-
0042525909
-
Essential role of RelA Ser311 phosphorylation by zetaPKC in NF-kappaB transcriptional activation
-
Duran A., Diaz-Meco M.T., and Moscat J. Essential role of RelA Ser311 phosphorylation by zetaPKC in NF-kappaB transcriptional activation. EMBO J. 22 (2003) 3910-3918
-
(2003)
EMBO J.
, vol.22
, pp. 3910-3918
-
-
Duran, A.1
Diaz-Meco, M.T.2
Moscat, J.3
-
26
-
-
9644262497
-
Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity
-
Buss H., Dorrie A., Lienhard Schmitz M., Frank R., Livingstone M., Resch K., and Kracht M. Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity. J. Biol. Chem. 48 (2004) 49571-49574
-
(2004)
J. Biol. Chem.
, vol.48
, pp. 49571-49574
-
-
Buss, H.1
Dorrie, A.2
Lienhard Schmitz, M.3
Frank, R.4
Livingstone, M.5
Resch, K.6
Kracht, M.7
-
27
-
-
6444223595
-
Insufficient p65 phosphorylation at S536 specifically contributes to the lack of NF-kappaB activation and transformation in resistant JB6 cells
-
Hu J., Nakano H., Sakurai H., and Colburn N.H. Insufficient p65 phosphorylation at S536 specifically contributes to the lack of NF-kappaB activation and transformation in resistant JB6 cells. Carcinogenesis 10 (2004) 1991-2003
-
(2004)
Carcinogenesis
, vol.10
, pp. 1991-2003
-
-
Hu, J.1
Nakano, H.2
Sakurai, H.3
Colburn, N.H.4
-
28
-
-
2542485441
-
PRb2/p130, vascular endothelial growth factor, p27(KIP1), and proliferating cell nuclear antigen expression in hepatocellular carcinoma: their clinical significance
-
Claudio P.P., Russo G., Kumar C.A., Minimo C., Farina A., Tutton S., Nuzzo G., Giuliante F., Angeloni G., Maria V., Vecchio F.M., Campli C.D., and Giordano A. PRb2/p130, vascular endothelial growth factor, p27(KIP1), and proliferating cell nuclear antigen expression in hepatocellular carcinoma: their clinical significance. Clin. Cancer Res. 10 (2004) 3509-3517
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 3509-3517
-
-
Claudio, P.P.1
Russo, G.2
Kumar, C.A.3
Minimo, C.4
Farina, A.5
Tutton, S.6
Nuzzo, G.7
Giuliante, F.8
Angeloni, G.9
Maria, V.10
Vecchio, F.M.11
Campli, C.D.12
Giordano, A.13
-
29
-
-
0034544619
-
Constitutive activation of nuclear factor kappaB in hepatocellular carcinoma
-
Tai D.I., Tsai S.L., Chang Y.H., Huang S.N., Chen T.C., Chang K.S., and Liaw Y.F. Constitutive activation of nuclear factor kappaB in hepatocellular carcinoma. Cancer 89 (2000) 2274-2281
-
(2000)
Cancer
, vol.89
, pp. 2274-2281
-
-
Tai, D.I.1
Tsai, S.L.2
Chang, Y.H.3
Huang, S.N.4
Chen, T.C.5
Chang, K.S.6
Liaw, Y.F.7
-
30
-
-
0034954377
-
Expression of nuclear factor-kappa B in hepatocellular carcinoma and its relation with the X protein of hepatitis B virus
-
Guo S.P., Wang W.L., Zhai Y.Q., and Zhao Y.L. Expression of nuclear factor-kappa B in hepatocellular carcinoma and its relation with the X protein of hepatitis B virus. World J. Gastroenterol. 7 (2001) 340-344
-
(2001)
World J. Gastroenterol.
, vol.7
, pp. 340-344
-
-
Guo, S.P.1
Wang, W.L.2
Zhai, Y.Q.3
Zhao, Y.L.4
-
31
-
-
4644324186
-
NF-kappaB functions as a tumour promoter in inflammation-associated cancer
-
Pikarsky E., Porat R.M., Stein I., Abramovitch R., Amit S., Kasem S., Gutkovich-Pyest E., Urieli-Shoval S., Galun E., and Ben-Neriah Y. NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature 431 (2004) 461-466
-
(2004)
Nature
, vol.431
, pp. 461-466
-
-
Pikarsky, E.1
Porat, R.M.2
Stein, I.3
Abramovitch, R.4
Amit, S.5
Kasem, S.6
Gutkovich-Pyest, E.7
Urieli-Shoval, S.8
Galun, E.9
Ben-Neriah, Y.10
-
32
-
-
1142275252
-
Suppression of metastasis by nuclear factor kappaB inhibitors in an in vivo lung metastasis model of chemically induced hepatocellular carcinoma
-
Futakuchi M., Ogawa K., Tamano S., Takahashi S., and Shirai T. Suppression of metastasis by nuclear factor kappaB inhibitors in an in vivo lung metastasis model of chemically induced hepatocellular carcinoma. Cancer Sci. 95 (2004) 18-24
-
(2004)
Cancer Sci.
, vol.95
, pp. 18-24
-
-
Futakuchi, M.1
Ogawa, K.2
Tamano, S.3
Takahashi, S.4
Shirai, T.5
-
33
-
-
4444232159
-
Expression and altered subcellular localization of the cyclin-dependent kinase inhibitor p27Kip1 in hepatocellular carcinoma
-
Nan K.J., Jing Z., and Gong L. Expression and altered subcellular localization of the cyclin-dependent kinase inhibitor p27Kip1 in hepatocellular carcinoma. World J. Gastroenterol. 10 (2004) 1425-1430
-
(2004)
World J. Gastroenterol.
, vol.10
, pp. 1425-1430
-
-
Nan, K.J.1
Jing, Z.2
Gong, L.3
-
34
-
-
0032995914
-
Expression and prognostic roles of the G1-S modulators in hepatocellular carcinoma: p27 independently predicts the recurrence
-
Ito Y., Matsuura N., Sakon M., Miyoshi E., Noda K., Takeda T., Umeshita K., Nagano H., Nakamori S., Dono K., Tsujimoto M., Nakahara M., Nakao K., Taniguchi N., and Monden M. Expression and prognostic roles of the G1-S modulators in hepatocellular carcinoma: p27 independently predicts the recurrence. Hepatology 30 (1999) 90-99
-
(1999)
Hepatology
, vol.30
, pp. 90-99
-
-
Ito, Y.1
Matsuura, N.2
Sakon, M.3
Miyoshi, E.4
Noda, K.5
Takeda, T.6
Umeshita, K.7
Nagano, H.8
Nakamori, S.9
Dono, K.10
Tsujimoto, M.11
Nakahara, M.12
Nakao, K.13
Taniguchi, N.14
Monden, M.15
-
35
-
-
0032561075
-
Reduced p27Kip1 expression in hepatocellular carcinomas
-
Hui A.M., Sun L., Kanai Y., Sakamoto M., and Hirohashi S. Reduced p27Kip1 expression in hepatocellular carcinomas. Cancer Lett. 132 (1998) 67-73
-
(1998)
Cancer Lett.
, vol.132
, pp. 67-73
-
-
Hui, A.M.1
Sun, L.2
Kanai, Y.3
Sakamoto, M.4
Hirohashi, S.5
-
36
-
-
0034691586
-
Decreased expression of p27 protein is associated with advanced tumor stage in hepatocellular carcinoma
-
Tannapfel A., Grund D., Katalinic A., Uhlmann D., Kockerling F., Haugwitz U., Wasner M., Hauss J., ngeland K., and Wittekind C. Decreased expression of p27 protein is associated with advanced tumor stage in hepatocellular carcinoma. Int. J. Cancer 89 (2000) 350-355
-
(2000)
Int. J. Cancer
, vol.89
, pp. 350-355
-
-
Tannapfel, A.1
Grund, D.2
Katalinic, A.3
Uhlmann, D.4
Kockerling, F.5
Haugwitz, U.6
Wasner, M.7
Hauss, J.8
ngeland, K.9
Wittekind, C.10
-
37
-
-
11144231977
-
Identification of small-molecule antagonists that inhibit an activator: coactivator interaction
-
Best J.L., Amezcua C.A., Mayr B., Flechner L., Murawsky C.M., Emerson B., Zor T., Gardner K.H., and Montminy M. Identification of small-molecule antagonists that inhibit an activator: coactivator interaction. Proc. Natl. Acad. Sci. USA 101 (2004) 17622-17627
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 17622-17627
-
-
Best, J.L.1
Amezcua, C.A.2
Mayr, B.3
Flechner, L.4
Murawsky, C.M.5
Emerson, B.6
Zor, T.7
Gardner, K.H.8
Montminy, M.9
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