-
1
-
-
0021101229
-
The 5-methylcytosine content of DNA from human tumors
-
Gama-Sosa M, Slagel V, Trewyn R, Oxenhandler R, Kuo K, et al. (1983) The 5-methylcytosine content of DNA from human tumors. Nucleic Acids Res 11: 6883-6894.
-
(1983)
Nucleic Acids Res
, vol.11
, pp. 6883-6894
-
-
Gama-Sosa, M.1
Slagel, V.2
Trewyn, R.3
Oxenhandler, R.4
Kuo, K.5
-
2
-
-
0020699979
-
Hypomethylation distinguishes genes of some human cancers from their normal counterparts
-
Feinberg A, Vogelstein B (1983) Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 301: 89-92.
-
(1983)
Nature
, vol.301
, pp. 89-92
-
-
Feinberg, A.1
Vogelstein, B.2
-
3
-
-
40849139208
-
Epigenetics in cancer
-
Esteller M (2008) Epigenetics in cancer. N Engl J Med 358: 1148-1159.
-
(2008)
N Engl J Med
, vol.358
, pp. 1148-1159
-
-
Esteller, M.1
-
4
-
-
24744471011
-
Causes and consequences of DNA hypomethylation in human cancer
-
Hoffmann M, Schulz W (2005) Causes and consequences of DNA hypomethylation in human cancer. Biochem Cell Biol 83: 296-321.
-
(2005)
Biochem Cell Biol
, vol.83
, pp. 296-321
-
-
Hoffmann, M.1
Schulz, W.2
-
5
-
-
33646338637
-
Quantitative analysis of associations between DNA hypermethylation, hypomethylation, and DNMT RNA levels in ovarian tumors
-
Ehrlich M, Woods C, Yu M, Dubeau L, Yang F, et al. (2006) Quantitative analysis of associations between DNA hypermethylation, hypomethylation, and DNMT RNA levels in ovarian tumors. Oncogene 25: 2636-2645.
-
(2006)
Oncogene
, vol.25
, pp. 2636-2645
-
-
Ehrlich, M.1
Woods, C.2
Yu, M.3
Dubeau, L.4
Yang, F.5
-
6
-
-
77955336443
-
UHRF1 plays a role in maintaining DNA methylation in mammalian cells
-
Bostick M, Kim J, Estéve P, Clark A, Pradhan S, et al. (2007) UHRF1 plays a role in maintaining DNA methylation in mammalian cells. Science 27: 2187-2197.
-
(2007)
Science
, vol.27
, pp. 2187-2197
-
-
Bostick, M.1
Kim, J.2
Estéve, P.3
Clark, A.4
Pradhan, S.5
-
7
-
-
0030770835
-
Human DNA- (cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1
-
Chuang LS, Ian HI, Koh TW, Ng HH, Xu G, et al. (1997) Human DNA- (cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1. Science 277: 1996-2000.
-
(1997)
Science
, vol.277
, pp. 1996-2000
-
-
Chuang, L.S.1
Ian, H.I.2
Koh, T.W.3
Ng, H.H.4
Xu, G.5
-
8
-
-
36849072573
-
The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA
-
Sharif J, Muto M, Takebayashi S, Suetake I, Iwamatsu A, et al. (2007) The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA. Nature 450: 908-912.
-
(2007)
Nature
, vol.450
, pp. 908-912
-
-
Sharif, J.1
Muto, M.2
Takebayashi, S.3
Suetake, I.4
Iwamatsu, A.5
-
9
-
-
41649115827
-
The interaction of the SRA domain of ICBP90 with a novel domain of DNMT1 is involved in the regulation of VEGF gene expression
-
Achour M, Jacq X, Rondé P, Alhosin M, Charlot C, et al. (2007) The interaction of the SRA domain of ICBP90 with a novel domain of DNMT1 is involved in the regulation of VEGF gene expression. Oncogene 27: 2187-2197.
-
(2007)
Oncogene
, vol.27
, pp. 2187-2197
-
-
Achour, M.1
Jacq, X.2
Rondé, P.3
Alhosin, M.4
Charlot, C.5
-
10
-
-
0242584454
-
Chromosomal instability and tumors promoted by DNA hypomethylation
-
Eden A, Gaudet F, Waghmare A, Jaenisch R (2003) Chromosomal instability and tumors promoted by DNA hypomethylation. Science 300: 455.
-
(2003)
Science
, vol.300
, pp. 455
-
-
Eden, A.1
Gaudet, F.2
Waghmare, A.3
Jaenisch, R.4
-
11
-
-
0032480226
-
DNA hypomethylation leads to elevated mutation rates
-
Chen R, Pettersson U, Beard C, Jackson-Grusby L, Jaenisch R (1998) DNA hypomethylation leads to elevated mutation rates. Nature 395: 89-93.
-
(1998)
Nature
, vol.395
, pp. 89-93
-
-
Chen, R.1
Pettersson, U.2
Beard, C.3
Jackson-Grusby, L.4
Jaenisch, R.5
-
12
-
-
53649097070
-
Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism
-
Arita K, Ariyoshi M, Tochio H, Nakamura Y, Shirakawa M (2008) Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism. Nature 455: 818-821.
-
(2008)
Nature
, vol.455
, pp. 818-821
-
-
Arita, K.1
Ariyoshi, M.2
Tochio, H.3
Nakamura, Y.4
Shirakawa, M.5
-
13
-
-
53649088595
-
Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1
-
Avvakumov G, Walker J, Xue S, Li Y, Duan S, et al. (2008) Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1. Nature 455: 822-825.
-
(2008)
Nature
, vol.455
, pp. 822-825
-
-
Avvakumov, G.1
Walker, J.2
Xue, S.3
Li, Y.4
Duan, S.5
-
14
-
-
53649089723
-
The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix
-
Hashimoto H, Horton J, Zhang X, Bostick M, Jacobsen S, et al. (2008) The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix. Nature 455: 826-829.
-
(2008)
Nature
, vol.455
, pp. 826-829
-
-
Hashimoto, H.1
Horton, J.2
Zhang, X.3
Bostick, M.4
Jacobsen, S.5
-
15
-
-
0242584449
-
Induction of tumors in mice by genomic hypomethylation
-
Gaudet F, Hodgson JG, Eden A, Jackson-Grusby L, Dausman J, et al. (2003) Induction of tumors in mice by genomic hypomethylation. Science 300: 489-492.
-
(2003)
Science
, vol.300
, pp. 489-492
-
-
Gaudet, F.1
Hodgson, J.G.2
Eden, A.3
Jackson-Grusby, L.4
Dausman, J.5
-
16
-
-
0037179870
-
Hypomethylation and hypermethylation of DNA in Wilms tumors
-
Ehrlich M, Jiang G, Fiala E, Dome J, Yu M, et al. (2002) Hypomethylation and hypermethylation of DNA in Wilms tumors. Oncogene 21: 6694-6702.
-
(2002)
Oncogene
, vol.21
, pp. 6694-6702
-
-
Ehrlich, M.1
Jiang, G.2
Fiala, E.3
Dome, J.4
Yu, M.5
-
17
-
-
33751209468
-
Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication
-
Estéve P, Chin H, Smallwood A, Feehery G, Gangisetty O, et al. (2006) Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication. Genes Dev 20: 3089-3103.
-
(2006)
Genes Dev
, vol.20
, pp. 3089-3103
-
-
Estéve, P.1
Chin, H.2
Smallwood, A.3
Feehery, G.4
Gangisetty, O.5
-
18
-
-
0042197254
-
DNMT1 is a component of a multiprotein DNA replication complex
-
Vertino P, Sekowski J, Coll J, Applegren N, Han S, et al. (2002) DNMT1 is a component of a multiprotein DNA replication complex. Cell Cycle 1: 416-423.
-
(2002)
Cell Cycle
, vol.1
, pp. 416-423
-
-
Vertino, P.1
Sekowski, J.2
Coll, J.3
Applegren, N.4
Han, S.5
-
19
-
-
0033945861
-
DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci
-
Rountree M, Bachman K, Baylin S (2000) DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci. Nat Genet 25: 269-277.
-
(2000)
Nat Genet
, vol.25
, pp. 269-277
-
-
Rountree, M.1
Bachman, K.2
Baylin, S.3
-
20
-
-
12144255958
-
Replicationindependent chromatin loading of Dnmt1 during G2 and M phases
-
Easwaran H, Schermelleh L, Leonhardt H, Cardoso M (2004) Replicationindependent chromatin loading of Dnmt1 during G2 and M phases. EMBO Rep 5: 1181-1186.
-
(2004)
EMBO Rep
, vol.5
, pp. 1181-1186
-
-
Easwaran, H.1
Schermelleh, L.2
Leonhardt, H.3
Cardoso, M.4
-
21
-
-
34547842515
-
Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation
-
Schermelleh L, Haemmer A, Spada F, Rösing N, Meilinger D, et al. (2007) Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation. Nucleic Acids Res 35: 4301-4312.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 4301-4312
-
-
Schermelleh, L.1
Haemmer, A.2
Spada, F.3
Rösing, N.4
Meilinger, D.5
-
22
-
-
33847348016
-
DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells
-
Spada F, Haemmer A, Kuch D, Rothbauer U, Schermelleh L, et al. (2007) DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells. J Cell Biol 176: 565-571.
-
(2007)
J Cell Biol
, vol.176
, pp. 565-571
-
-
Spada, F.1
Haemmer, A.2
Kuch, D.3
Rothbauer, U.4
Schermelleh, L.5
-
23
-
-
0033988813
-
DNA methyltransferase Dnmt1 associates with histone deacetylase activity
-
Fuks F, Burgers WA, Brehm A, Hughes-Davies L, Kouzarides T (2000) DNA methyltransferase Dnmt1 associates with histone deacetylase activity. Nat Genet 24: 88-91.
-
(2000)
Nat Genet
, vol.24
, pp. 88-91
-
-
Fuks, F.1
Burgers, W.A.2
Brehm, A.3
Hughes-Davies, L.4
Kouzarides, T.5
-
24
-
-
0033919595
-
DNMT1 forms a complex with Rb
-
Robertson KD, Ait-Si-Ali S, Yokochi T, Wade PA, Jones PL, et al. (2000) DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters. 25: 338-342.
-
(2000)
E2F1 and HDAC1 and Represses Transcription From E2F-responsive Promoters
, vol.25
, pp. 338-342
-
-
Robertson, K.D.1
Ait-Si-Ali, S.2
Yokochi, T.3
Wade, P.A.4
Jones, P.L.5
-
25
-
-
0035425048
-
PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo
-
Dai C, Celestino JC, Okada Y, Louis DN, Fuller GN, et al. (2001) PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo. Genes Dev 15: 1913-1925.
-
(2001)
Genes Dev
, vol.15
, pp. 1913-1925
-
-
Dai, C.1
Celestino, J.C.2
Okada, Y.3
Louis, D.N.4
Fuller, G.N.5
-
26
-
-
0034020459
-
Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice
-
Holland E, Celestino J, Dai C, Schaefer L, Sawaya R, et al. (2000) Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice. Nat Genet 25: 55-57.
-
(2000)
Nat Genet
, vol.25
, pp. 55-57
-
-
Holland, E.1
Celestino, J.2
Dai, C.3
Schaefer, L.4
Sawaya, R.5
-
27
-
-
0034626988
-
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
-
Esteller M, Garcia-Foncillas J, Andion E, Goodman SN, Hidalgo OF, et al. (2000) Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 343: 1350-1354.
-
(2000)
N Engl J Med
, vol.343
, pp. 1350-1354
-
-
Esteller, M.1
Garcia-Foncillas, J.2
Andion, E.3
Goodman, S.N.4
Hidalgo, O.F.5
-
28
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
Hegi M, Diserens A, Gorlia T, Hamou M, de Tribolet N, et al. (2005) MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 352: 991-1003.
-
(2005)
N Engl J Med
, vol.352
, pp. 991-1003
-
-
Hegi, M.1
Diserens, A.2
Gorlia, T.3
Hamou, M.4
de Tribolet, N.5
-
29
-
-
34447120194
-
Nuclear and cytoplasmic survivin: Molecular mechanism, prognostic, and therapeutic potential
-
Stauber R, Mann W, Knauer S (2007) Nuclear and cytoplasmic survivin: molecular mechanism, prognostic, and therapeutic potential. Cancer Res 67: 5999-6002.
-
(2007)
Cancer Res
, vol.67
, pp. 5999-6002
-
-
Stauber, R.1
Mann, W.2
Knauer, S.3
-
30
-
-
0032585642
-
Novel regions of allelic deletion on chromosome 18p in tumors of the lung, brain and breast
-
Tran Y, Benbatoul K, Gorse K, Rempel S, Futreal A, et al. (1998) Novel regions of allelic deletion on chromosome 18p in tumors of the lung, brain and breast. Oncogene 17: 3499-3505.
-
(1998)
Oncogene
, vol.17
, pp. 3499-3505
-
-
Tran, Y.1
Benbatoul, K.2
Gorse, K.3
Rempel, S.4
Futreal, A.5
-
31
-
-
0030778206
-
Molecular changes during the genesis of human gliomas
-
Sehgal A (1998) Molecular changes during the genesis of human gliomas. Semin Surg Oncol 14: 3-12.
-
(1998)
Semin Surg Oncol
, vol.14
, pp. 3-12
-
-
Sehgal, A.1
-
32
-
-
5444268751
-
DMB (DNMT-magnetic beads) assay: Measuring DNA methyltransferase activity in vitro
-
Yokochi T, Robertson KD (2004) DMB (DNMT-magnetic beads) assay: measuring DNA methyltransferase activity in vitro. Methods Mol Biol 287: 285-296.
-
(2004)
Methods Mol Biol
, vol.287
, pp. 285-296
-
-
Yokochi, T.1
Robertson, K.D.2
-
33
-
-
0038382972
-
Nonredundant role of Bax and Bak in Bid-mediated apoptosis
-
Cartron PF, Juin P, Oliver L, Martin S, Meflah K, et al. (2003) Nonredundant role of Bax and Bak in Bid-mediated apoptosis. Mol Cell Biol 23: 4701-4712.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 4701-4712
-
-
Cartron, P.F.1
Juin, P.2
Oliver, L.3
Martin, S.4
Meflah, K.5
|