Proanthocyanidins from the American Cranberry (Vaccinium macrocarpon) inhibit matrix metalloproteinase-2 and matrix metalloproteinase-9 activity in human prostate cancer cells via alterations in multiple cellular signalling pathways

Journal of Cellular Biochemistry

Volumn 111, Issue 3, 2010, Pages 742-754

  Déziel, Bob A ^a   Pate, Kunal ^a,b   Neto, Catherine ^b   Gottschall Pass, Katherine ^a   Hurta, Robert A R ^a  

^a UNIVERSITY OF PRINCE EDWARD ISLAND   (Canada)

^b UNIVERSITY OF MASSACHUSETTS DARTMOUTH   (United States)

Author keywords

Cellular Signalling Pathways; Cranberry Proanthocyanidins; Matrix Metalloproteinases; Prostate Cancer

Indexed keywords

ANTINEOPLASTIC AGENT; CD147 ANTIGEN; GELATINASE A; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROANTHOCYANIDIN DERIVATIVE; PROTEIN C FOS; PROTEIN KINASE B; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSCRIPTION FACTOR RELA;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL VIABILITY; CRANBERRY; DRUG EFFECT; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; ZYMOGRAPHY;

ANTIGENS, CD147; CELL LINE, TUMOR; CELL SURVIVAL; GENE EXPRESSION REGULATION; HUMANS; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROANTHOCYANIDINS; PROSTATIC NEOPLASMS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1; VACCINIUM MACROCARPON;

VACCINIUM MACROCARPON;

EID: 77957558059     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22761     Document Type: Article

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