Acacetin, a flavonoid, inhibits the invasion and migration of human prostate cancer DU145 cells via inactivation of the p38 MAPK signaling pathway

Molecular and Cellular Biochemistry

Volumn 333, Issue 1-2, 2010, Pages 279-291

  Shen, Kun Hung ^a,b,c   Hung, Shun Hsing ^a   Yin, Li Te ^d   Huang, Chun Shui ^e   Chao, Chang Hung ^e   Liu, Chein Liang ^a   Shih, Yuan Wei ^d  

^a CHI MEI MEDICAL CENTER   (Taiwan)

^b CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d CHUNG HWA UNIVERSITY OF MEDICAL TECHNOLOGY   (Taiwan)

^e KUO GENERAL HOSPITAL   (Taiwan)

Author keywords

Acacetin; Invasion; Migration; MMP 2; MMP 9; P38 MAPK; U PA

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACACETIN; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN C FOS; PROTEIN C JUN; TRANSCRIPTION FACTOR AP 1; UROKINASE;

ARTICLE; CANCER CELL; CELL ADHESION; CELL INVASION; CELL MIGRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG STRUCTURE; HUMAN; HUMAN CELL; METASTASIS INHIBITION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL MOVEMENT; FLAVONES; FLAVONOIDS; HUMANS; MALE; MATRIX METALLOPROTEINASES; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROSTATIC NEOPLASMS; RNA, MESSENGER; SIGNAL TRANSDUCTION; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 73449134066     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-009-0229-8     Document Type: Article

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