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Volumn 56, Issue 22, 2008, Pages 10574-10581

Selenocystine induces S-phase arrest and apoptosis in human breast adenocarcinoma MCF-7 cells by modulating ERK and Akt phosphorylation

Author keywords

Akt; Apoptosis; Cell cycle arrest; ERK; MCF 7 cells; Selenium; Selenocystine

Indexed keywords

ANTINEOPLASTIC AGENT; CYSTINE; DRUG DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE; ORGANOSELENIUM DERIVATIVE; PROTEIN KINASE B; SELENOCYSTINE;

EID: 57849084052     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf802125t     Document Type: Article
Times cited : (117)

References (36)
  • 1
    • 0042093614 scopus 로고    scopus 로고
    • Multi-ethnic differences in breast cancer current concepts and future directions
    • Perera, N. M.; Gui, G. P. Multi-ethnic differences in breast cancer current concepts and future directions. Int. J. Cancer 2003, 106, 463-467.
    • (2003) Int. J. Cancer , vol.106 , pp. 463-467
    • Perera, N.M.1    Gui, G.P.2
  • 2
  • 3
    • 0142166328 scopus 로고    scopus 로고
    • Surh, Y. J. Cancer chemoprevention with dietary phytochemicals. Nat. Rev. Cancer 2003, 3, 768-780.
    • Surh, Y. J. Cancer chemoprevention with dietary phytochemicals. Nat. Rev. Cancer 2003, 3, 768-780.
  • 4
    • 43949138899 scopus 로고    scopus 로고
    • Mechanisms and strategies to overcome chemotherapy resistance in metastatic breast cancer
    • Coley, H. M. Mechanisms and strategies to overcome chemotherapy resistance in metastatic breast cancer. Cancer Treat. Rev. 2008, 34, 378-390.
    • (2008) Cancer Treat. Rev , vol.34 , pp. 378-390
    • Coley, H.M.1
  • 5
    • 0035279153 scopus 로고    scopus 로고
    • Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis
    • Fulda, S.; Meyer, E.; Friesen, C.; Susin, S. A.; Kroemer, G.; Debatin, K. M. Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis. Oncogene 2001, 20, 1063-1075.
    • (2001) Oncogene , vol.20 , pp. 1063-1075
    • Fulda, S.1    Meyer, E.2    Friesen, C.3    Susin, S.A.4    Kroemer, G.5    Debatin, K.M.6
  • 6
    • 0034662094 scopus 로고    scopus 로고
    • The importance of selenium to human health
    • Rayman, M. P. The importance of selenium to human health. Lancet 2000, 356, 233-241.
    • (2000) Lancet , vol.356 , pp. 233-241
    • Rayman, M.P.1
  • 7
    • 1542724502 scopus 로고    scopus 로고
    • Apoptosis is a critical cellular event in cancer chemoprevention and chemotherapy by selenium compounds
    • Sinha, R.; El-Bayoumy, K. Apoptosis is a critical cellular event in cancer chemoprevention and chemotherapy by selenium compounds. Curr. Cancer Drug Targets 2004, 4, 13-28.
    • (2004) Curr. Cancer Drug Targets , vol.4 , pp. 13-28
    • Sinha, R.1    El-Bayoumy, K.2
  • 8
    • 0034485903 scopus 로고    scopus 로고
    • Anticarcinogenic effects of selenium
    • Schrauzer, G. N. Anticarcinogenic effects of selenium. Cell. Mol. Life Sci. 2000, 57, 1864-1873.
    • (2000) Cell. Mol. Life Sci , vol.57 , pp. 1864-1873
    • Schrauzer, G.N.1
  • 9
    • 34147162338 scopus 로고    scopus 로고
    • Selenium sensitizes MCF-7 breast cancer cells to doxorubicin-induced apoptosis through modulation of phospho-Akt and its downstream substrates
    • Li, S.; Zhou, Y.; Wang, R.; Zhang, H.; Dong, Y.; Ip, C. Selenium sensitizes MCF-7 breast cancer cells to doxorubicin-induced apoptosis through modulation of phospho-Akt and its downstream substrates. Mol. Cancer Ther. 2007, 6, 1031-1038.
    • (2007) Mol. Cancer Ther , vol.6 , pp. 1031-1038
    • Li, S.1    Zhou, Y.2    Wang, R.3    Zhang, H.4    Dong, Y.5    Ip, C.6
  • 10
    • 0033452559 scopus 로고    scopus 로고
    • Chemoprevention of mammary cancer with Se-allylselenocysteine and other selenoamino acids in the rat
    • Ip, C.; Zhu, Z.; Thompson, H. J.; Lisk, D.; Ganther, H. E. Chemoprevention of mammary cancer with Se-allylselenocysteine and other selenoamino acids in the rat. Anticancer Res. 1999, 19, 2875-2880.
    • (1999) Anticancer Res , vol.19 , pp. 2875-2880
    • Ip, C.1    Zhu, Z.2    Thompson, H.J.3    Lisk, D.4    Ganther, H.E.5
  • 11
    • 3042693150 scopus 로고    scopus 로고
    • Mechanisms of mammary cancer chemoprevention by organoselenium compounds
    • El-Bayoumy, K.; Sinha, R. Mechanisms of mammary cancer chemoprevention by organoselenium compounds. Mutat. Res. 2004, 551, 181-197.
    • (2004) Mutat. Res , vol.551 , pp. 181-197
    • El-Bayoumy, K.1    Sinha, R.2
  • 12
    • 38949104369 scopus 로고    scopus 로고
    • Mitochondria-mediated apoptosis in human breast carcinoma MCF-7 cells induced by a novel selenadiazole derivative
    • Chen, T.; Zheng, W.; Wong, Y.-S.; Yang, F. Mitochondria-mediated apoptosis in human breast carcinoma MCF-7 cells induced by a novel selenadiazole derivative. Biomed. Pharmacother. 2008, 62, 77-84.
    • (2008) Biomed. Pharmacother , vol.62 , pp. 77-84
    • Chen, T.1    Zheng, W.2    Wong, Y.-S.3    Yang, F.4
  • 13
    • 58949088847 scopus 로고    scopus 로고
    • Chen, T.; Wong, Y.-S. Selenocystine induces reactive oxygen species-mediated apoptosis in human cancer cells. Biomed. Pharmacother. 2008, xxxx, (doi: 10.1016/j.biopha.2008.03.009).
    • Chen, T.; Wong, Y.-S. Selenocystine induces reactive oxygen species-mediated apoptosis in human cancer cells. Biomed. Pharmacother. 2008, xxxx, (doi: 10.1016/j.biopha.2008.03.009).
  • 14
    • 47349114766 scopus 로고    scopus 로고
    • In vitro antioxidant and antiproliferative activities of selenium-containing phycocyanin from selenium-enriched Spirulina platensis
    • Chen, T.; Wong, Y.-S. In vitro antioxidant and antiproliferative activities of selenium-containing phycocyanin from selenium-enriched Spirulina platensis. J. Agric. Food Chem. 2008, 56, 4352-4358.
    • (2008) J. Agric. Food Chem , vol.56 , pp. 4352-4358
    • Chen, T.1    Wong, Y.-S.2
  • 15
    • 39749193987 scopus 로고    scopus 로고
    • Methylseleninic acid enhances taxane drug efficacy against human prostate cancer and down-regulates antiapoptotic proteins Bcl-XL and survivin
    • Hu, H.; Li, G. X.; Wang, L.; Watts, J.; Combs, G. F., Jr.; Lu, J. Methylseleninic acid enhances taxane drug efficacy against human prostate cancer and down-regulates antiapoptotic proteins Bcl-XL and survivin. Clin. Cancer Res. 2008, 14, 1150-1158.
    • (2008) Clin. Cancer Res , vol.14 , pp. 1150-1158
    • Hu, H.1    Li, G.X.2    Wang, L.3    Watts, J.4    Combs Jr., G.F.5    Lu, J.6
  • 16
    • 33644542078 scopus 로고    scopus 로고
    • Expression of p53 enhances selenite-induced superoxide production and apoptosis in human prostate cancer cells
    • Zhao, R.; Xiang, N.; Domann, F. E.; Zhong, W. Expression of p53 enhances selenite-induced superoxide production and apoptosis in human prostate cancer cells. Cancer Res. 2006, 66, 2296-2304.
    • (2006) Cancer Res , vol.66 , pp. 2296-2304
    • Zhao, R.1    Xiang, N.2    Domann, F.E.3    Zhong, W.4
  • 17
    • 0346707259 scopus 로고    scopus 로고
    • Selenium and its relationship to cancer an update
    • Whanger, P. D. Selenium and its relationship to cancer an update. Br. J. Nutr. 2004, 91, 11-28.
    • (2004) Br. J. Nutr , vol.91 , pp. 11-28
    • Whanger, P.D.1
  • 18
    • 33244474951 scopus 로고    scopus 로고
    • Effect of selenium-containing compounds on hepatic chemoprotective enzymes in mice
    • El-Sayed, W. M.; Aboul-Fadl, T.; Lamb, J. G.; Roberts, J. C.; Franklin, M. R. Effect of selenium-containing compounds on hepatic chemoprotective enzymes in mice. Toxicology 2006, 220, 179-188.
    • (2006) Toxicology , vol.220 , pp. 179-188
    • El-Sayed, W.M.1    Aboul-Fadl, T.2    Lamb, J.G.3    Roberts, J.C.4    Franklin, M.R.5
  • 20
    • 2942593991 scopus 로고    scopus 로고
    • ROS stress in cancer cells and therapeutic implications
    • Pelicano, H.; Carney, D.; Huang, P. ROS stress in cancer cells and therapeutic implications. Drug Resist. Update 2004, 7, 97-110.
    • (2004) Drug Resist. Update , vol.7 , pp. 97-110
    • Pelicano, H.1    Carney, D.2    Huang, P.3
  • 21
    • 0141864377 scopus 로고    scopus 로고
    • Apoptosis, chemoresistance, and breast cancer: Insights from the MCF-7 cell model system
    • Simstein, R.; Burow, M.; Parker, A.; Weldon, C.; Beckman, B. Apoptosis, chemoresistance, and breast cancer: insights from the MCF-7 cell model system. Exp. Biol. Med 2003, 228, 995-1003.
    • (2003) Exp. Biol. Med , vol.228 , pp. 995-1003
    • Simstein, R.1    Burow, M.2    Parker, A.3    Weldon, C.4    Beckman, B.5
  • 23
    • 33750909999 scopus 로고    scopus 로고
    • Reactive oxygen species-induced activation of the MAP kinase signaling pathways
    • McCubrey, J. A.; Lahair, M. M.; Franklin, R. A. Reactive oxygen species-induced activation of the MAP kinase signaling pathways. Antioxid. Redox Signal. 2006, 8, 1775-1789.
    • (2006) Antioxid. Redox Signal , vol.8 , pp. 1775-1789
    • McCubrey, J.A.1    Lahair, M.M.2    Franklin, R.A.3
  • 24
    • 0034845958 scopus 로고    scopus 로고
    • PKB/Akt: A key mediator of cell proliferation, survival and insulin responses
    • Lawlor, M. A.; Alessi, D. R. PKB/Akt: a key mediator of cell proliferation, survival and insulin responses. J. Cell Sci. 2001, 114, 2903-2910.
    • (2001) J. Cell Sci , vol.114 , pp. 2903-2910
    • Lawlor, M.A.1    Alessi, D.R.2
  • 25
    • 0036848491 scopus 로고    scopus 로고
    • The role of MAPK pathways in the action of chemotherapeutic drugs
    • Boldt, S.; Weidle, U. H.; Kolch, W. The role of MAPK pathways in the action of chemotherapeutic drugs. Carcinogenesis 2002, 23, 1831-1838.
    • (2002) Carcinogenesis , vol.23 , pp. 1831-1838
    • Boldt, S.1    Weidle, U.H.2    Kolch, W.3
  • 26
    • 0036581949 scopus 로고    scopus 로고
    • Phytochemicals as cell cycle modulators - a less toxic approach in halting human cancers
    • Singh, R. P.; Dhanalakshmi, S.; Agarwal, R. Phytochemicals as cell cycle modulators - a less toxic approach in halting human cancers. Cell Cycle 2002, 1, 156-161.
    • (2002) Cell Cycle , vol.1 , pp. 156-161
    • Singh, R.P.1    Dhanalakshmi, S.2    Agarwal, R.3
  • 27
    • 0036679627 scopus 로고    scopus 로고
    • Progress toward the development of agents to modulate the cell cycle
    • Toogood, P. L. Progress toward the development of agents to modulate the cell cycle. Curr. Opin. Chem. Biol. 2002, 6, 472-478.
    • (2002) Curr. Opin. Chem. Biol , vol.6 , pp. 472-478
    • Toogood, P.L.1
  • 28
    • 0035476847 scopus 로고    scopus 로고
    • Redox-mediated effects of selenium on apoptosis and cell cycle in the LNCaP human prostate cancer cell line
    • Zhong, W.; Oberley, T. D. Redox-mediated effects of selenium on apoptosis and cell cycle in the LNCaP human prostate cancer cell line. Cancer Res. 2001, 61, 7071-7078.
    • (2001) Cancer Res , vol.61 , pp. 7071-7078
    • Zhong, W.1    Oberley, T.D.2
  • 29
    • 36749042560 scopus 로고    scopus 로고
    • Methylseleninic acid inhibits microvascular endothelial G1 cell cycle progression and decreases tumor microvessel density
    • Wang, Z.; Hu, H.; Li, G.; Lee, H. J.; Jiang, G.; Kim, S. H.; Lu, J. Methylseleninic acid inhibits microvascular endothelial G1 cell cycle progression and decreases tumor microvessel density. Int. J. Cancer 2008, 122, 15-24.
    • (2008) Int. J. Cancer , vol.122 , pp. 15-24
    • Wang, Z.1    Hu, H.2    Li, G.3    Lee, H.J.4    Jiang, G.5    Kim, S.H.6    Lu, J.7
  • 30
    • 0036569697 scopus 로고    scopus 로고
    • Selenium modulation of cell proliferation and cell cycle biomarkers in human prostate carcinoma cell lines
    • Venkateswaran, V.; Klotz, L. H.; Fleshner, N. E. Selenium modulation of cell proliferation and cell cycle biomarkers in human prostate carcinoma cell lines. Cancer Res. 2002, 62, 2540-2545.
    • (2002) Cancer Res , vol.62 , pp. 2540-2545
    • Venkateswaran, V.1    Klotz, L.H.2    Fleshner, N.E.3
  • 31
    • 1242312903 scopus 로고    scopus 로고
    • Distinct effects of methylseleninic acid versus selenite on apoptosis, cell cycle, and protein kinase pathways in DU145 human prostate cancer cells
    • Jiang, C.; Wang, Z.; Ganther, H.; Lu, J. Distinct effects of methylseleninic acid versus selenite on apoptosis, cell cycle, and protein kinase pathways in DU145 human prostate cancer cells. Mol. Cancer Ther. 2002, 1, 1059-1066.
    • (2002) Mol. Cancer Ther , vol.1 , pp. 1059-1066
    • Jiang, C.1    Wang, Z.2    Ganther, H.3    Lu, J.4
  • 32
    • 33646764234 scopus 로고    scopus 로고
    • Selenomethionine induces p53 mediated cell cycle arrest and apoptosis in human colon cancer cells
    • Goel, A.; Fuerst, F.; Hotchkiss, E.; Boland, C. R. Selenomethionine induces p53 mediated cell cycle arrest and apoptosis in human colon cancer cells. Cancer Biol. Ther. 2006, 5, 529-535.
    • (2006) Cancer Biol. Ther , vol.5 , pp. 529-535
    • Goel, A.1    Fuerst, F.2    Hotchkiss, E.3    Boland, C.R.4
  • 33
    • 33644874428 scopus 로고    scopus 로고
    • Se-methylselenocysteine inhibits phosphatidylinositol 3-kinase activity of mouse mammary epithelial tumor cells in vitro
    • Unni, E.; Koul, D.; Yung, W. K.; Sinha, R. Se-methylselenocysteine inhibits phosphatidylinositol 3-kinase activity of mouse mammary epithelial tumor cells in vitro. Breast Cancer Res. 2005, 7, 699-707.
    • (2005) Breast Cancer Res , vol.7 , pp. 699-707
    • Unni, E.1    Koul, D.2    Yung, W.K.3    Sinha, R.4
  • 34
    • 0034057320 scopus 로고    scopus 로고
    • Apoptosis in cancer
    • Lowe, S. W.; Lin, A. W. Apoptosis in cancer. Carcinogenesis 2000, 21, 485-495.
    • (2000) Carcinogenesis , vol.21 , pp. 485-495
    • Lowe, S.W.1    Lin, A.W.2
  • 35
    • 0037032817 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
    • Johnson, G. L.; Lapadat, R. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 2002, 298, 1911-1912.
    • (2002) Science , vol.298 , pp. 1911-1912
    • Johnson, G.L.1    Lapadat, R.2
  • 36
    • 24944441858 scopus 로고    scopus 로고
    • PKB/AKT and ERK regulation of caspase-mediated apoptosis by methylseleninic acid in LNCaP prostate cancer cells
    • Hu, H.; Jiang, C.; Li, G.; Lu, J. PKB/AKT and ERK regulation of caspase-mediated apoptosis by methylseleninic acid in LNCaP prostate cancer cells. Carcinogenesis 2005, 26, 1374-1381.
    • (2005) Carcinogenesis , vol.26 , pp. 1374-1381
    • Hu, H.1    Jiang, C.2    Li, G.3    Lu, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.