메뉴 건너뛰기




Volumn 299, Issue 4, 2010, Pages

Optical molecular imaging and its emerging role in colorectal cancer

Author keywords

Animal studies; Cancer genetics; Endoscopy; Fluorescence

Indexed keywords

ALPHA5 INTEGRIN; BETA3 INTEGRIN; BEVACIZUMAB; CATHEPSIN B; CELECOXIB; CETUXIMAB; CYCLOOXYGENASE 2; DNA TOPOISOMERASE; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FLUOROURACIL; FOLATE RECEPTOR; FOLINIC ACID; GELATINASE A; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INDOCYANINE GREEN; INTERLEUKIN 1BETA CONVERTING ENZYME; IRINOTECAN; LIPOCORTIN 5; OXALIPLATIN; PANITUMUMAB; PHOSPHATIDYLSERINE; THYMIDYLATE SYNTHASE; TRASTUZUMAB; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN; VASCULOTROPIN RECEPTOR; ANTINEOPLASTIC AGENT;

EID: 77957345405     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00195.2010     Document Type: Review
Times cited : (19)

References (133)
  • 1
    • 49949093558 scopus 로고    scopus 로고
    • Gastrointestinal endoscopy nears "the molecular era"
    • Aisenberg J. Gastrointestinal endoscopy nears "the molecular era". Gastrointest Endosc 68: 528-530, 2008.
    • (2008) Gastrointest Endosc , vol.68 , pp. 528-530
    • Aisenberg, J.1
  • 2
    • 65349189958 scopus 로고    scopus 로고
    • American Society of Clinical Oncology provisional clinical opinion: Testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy
    • Allegra CJ, Jessup JM, Somerfield MR, Hamilton SR, Hammond EH, Hayes DF, McAllister PK, Morton RF, Schilsky RL. American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy. J Clin Oncol 27: 2091-2096, 2009.
    • (2009) J Clin Oncol , vol.27 , pp. 2091-2096
    • Allegra, C.J.1    Jessup, J.M.2    Somerfield, M.R.3    Hamilton, S.R.4    Hammond, E.H.5    Hayes, D.F.6    McAllister, P.K.7    Morton, R.F.8    Schilsky, R.L.9
  • 7
    • 36749036711 scopus 로고    scopus 로고
    • In vivo diagnosis of epidermal growth factor receptor expression using molecular imaging with a cocktail of optically labeled monoclonal antibodies
    • DOI 10.1158/1078-0432.CCR-07-1119
    • Barrett T, Koyama Y, Hama Y, Ravizzini G, Shin IS, Jang BS, Paik CH, Urano Y, Choyke PL, Kobayashi H. In vivo diagnosis of epidermal growth factor receptor expression using molecular imaging with a cocktail of optically labeled monoclonal antibodies. Clin Cancer Res 13: 6639-6648, 2007. (Pubitemid 350206799)
    • (2007) Clinical Cancer Research , vol.13 , Issue.22 , pp. 6639-6648
    • Barrett, T.1    Koyama, Y.2    Hama, Y.3    Ravizzini, G.4    In, S.S.5    Jang, B.-S.6    Paik, C.H.7    Urano, Y.8    Choyke, P.L.9    Kobayashi, H.10
  • 8
    • 0037967272 scopus 로고    scopus 로고
    • Tumorigenesis and the angiogenic switch
    • Bergers G, Benjamin LE. Tumorigenesis and the angiogenic switch. Nat Rev Cancer 3: 401-410, 2003.
    • (2003) Nat Rev Cancer , vol.3 , pp. 401-410
    • Bergers, G.1    Benjamin, L.E.2
  • 9
    • 0038756512 scopus 로고    scopus 로고
    • Optical-based molecular imaging: Contrast agents and potential medical applications
    • Bremer C, Ntziachristos V, Weissleder R. Optical-based molecular imaging: contrast agents and potential medical applications. Eur Radiol 13: 231-243, 2003.
    • (2003) Eur Radiol , vol.13 , pp. 231-243
    • Bremer, C.1    Ntziachristos, V.2    Weissleder, R.3
  • 10
    • 0034954524 scopus 로고    scopus 로고
    • In vivo molecular target assessment of matrix metalloproteinase inhibition
    • Bremer C, Tung C, Weissleder R. In vivo molecular target assessment of matrix metalloproteinase inhibition. Nat Med 7: 743-748, 2001.
    • (2001) Nat Med , vol.7 , pp. 743-748
    • Bremer, C.1    Tung, C.2    Weissleder, R.3
  • 12
    • 0035297578 scopus 로고    scopus 로고
    • Novel fluorescent contrast agents for optical imaging of in vivo tumors based on a receptor-targeted dye-peptide conjugate platform
    • Bugaj JE, Achilefu S, Dorshow RB, Rajagopalan R. Novel fluorescent contrast agents for optical imaging of in vivo tumors based on a receptor-targeted dye-peptide conjugate platform. J Biomed Opt 6: 122-133, 2001.
    • (2001) J Biomed Opt , vol.6 , pp. 122-133
    • Bugaj, J.E.1    Achilefu, S.2    Dorshow, R.B.3    Rajagopalan, R.4
  • 13
    • 46749108882 scopus 로고    scopus 로고
    • Multimodality molecular imaging of tumor angiogenesis
    • DOI 10.2967/jnumed.107.045922
    • Cai W, Chen X. Multimodality molecular imaging of tumor angiogenesis. J Nucl Med 49, Suppl 2: 113S-128S, 2008. (Pubitemid 351948040)
    • (2008) Journal of Nuclear Medicine , vol.49 , Issue.SUPPL. 6
    • Cai, W.1    Chen, X.2
  • 14
    • 36048993546 scopus 로고    scopus 로고
    • Nanoplatforms for targeted molecular imaging in living subjects
    • Cai W, Chen X. Nanoplatforms for targeted molecular imaging in living subjects. Small 3: 1840-1854, 2007.
    • (2007) Small , vol.3 , pp. 1840-1854
    • Cai, W.1    Chen, X.2
  • 15
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 407: 249-257, 2000.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 17
    • 48249123483 scopus 로고    scopus 로고
    • In vivo optical molecular imaging of vascular endothelial growth factor for monitoring cancer treatment
    • Chang SK, Rizvi I, Solban N, Hasan T. In vivo optical molecular imaging of vascular endothelial growth factor for monitoring cancer treatment. Clin Cancer Res 14: 4146-4153, 2008.
    • (2008) Clin Cancer Res , vol.14 , pp. 4146-4153
    • Chang, S.K.1    Rizvi, I.2    Solban, N.3    Hasan, T.4
  • 18
    • 67349152647 scopus 로고    scopus 로고
    • Treatment in advanced colorectal cancer: What, when and how?
    • Chau I, Cunningham D. Treatment in advanced colorectal cancer: what, when and how? Br J Cancer 100: 1704-1719, 2009.
    • (2009) Br J Cancer , vol.100 , pp. 1704-1719
    • Chau, I.1    Cunningham, D.2
  • 19
    • 17144416842 scopus 로고    scopus 로고
    • Near-infrared fluorescent imaging of matrix metalloproteinase activity after myocardial infarction
    • Chen J, Tung C, Allport J, Chen S, Weissleder R. Near-infrared fluorescent imaging of matrix metalloproteinase activity after myocardial infarction. Circulation 111: 1800-1805, 2005.
    • (2005) Circulation , vol.111 , pp. 1800-1805
    • Chen, J.1    Tung, C.2    Allport, J.3    Chen, S.4    Weissleder, R.5
  • 21
    • 27944438239 scopus 로고    scopus 로고
    • Arthritis imaging using a near-infrared fluorescence folate-targeted probe
    • Chen WT, Mahmood U, Weissleder R, Tung CH. Arthritis imaging using a near-infrared fluorescence folate-targeted probe. Arthritis Res Ther 7: R310-R317, 2005.
    • (2005) Arthritis Res Ther , vol.7
    • Chen, W.T.1    Mahmood, U.2    Weissleder, R.3    Tung, C.H.4
  • 23
    • 0141629373 scopus 로고    scopus 로고
    • Cyclo-oxygenase 2 inhibition in colorectal cancer therapy
    • DOI 10.1002/bjs.4297
    • Church RD, Fleshman JW, McLeod HL. Cyclo-oxygenase 2 inhibition in colorectal cancer therapy. Br J Surg 90: 1055-1067, 2003. (Pubitemid 37152162)
    • (2003) British Journal of Surgery , vol.90 , Issue.9 , pp. 1055-1067
    • Church, R.D.1    Fleshman, J.W.2    McLeod, H.L.3
  • 24
    • 32944481882 scopus 로고    scopus 로고
    • Counting heads in the war against cancer: Defining the role of annexin A5 imaging in cancer treatment and surveillance
    • DOI 10.1158/0008-5472.CAN-05-3000
    • Corsten MF, Hofstra L, Narula J, Reutelingsperger CPM. Counting heads in the war against cancer: defining the role of annexin A5 imaging in cancer treatment and surveillance. Cancer Res 66: 1255-1260, 2006. (Pubitemid 43259900)
    • (2006) Cancer Research , vol.66 , Issue.3 , pp. 1255-1260
    • Corsten, M.F.1    Hofstra, L.2    Narula, J.3    Reutelingsperger, C.P.M.4
  • 29
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 61: 759-767, 1990.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 30
    • 0037278885 scopus 로고    scopus 로고
    • Integrin adhesion receptors in tumor metastasis
    • Felding-Habermann B. Integrin adhesion receptors in tumor metastasis. Clin Exp Metastasis 20: 203-213, 2003.
    • (2003) Clin Exp Metastasis , vol.20 , pp. 203-213
    • Felding-Habermann, B.1
  • 31
    • 0036782278 scopus 로고    scopus 로고
    • VEGF and the quest for tumour angiogenesis factors
    • DOI 10.1038/nrc909
    • Ferrara N. VEGF and the quest for tumour angiogenesis factors. Nat Rev Cancer 2: 795-803, 2002. (Pubitemid 37328914)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.10 , pp. 795-803
    • Ferrara, N.1
  • 32
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • DOI 10.1210/er.18.1.4
    • Ferrara N, Davis-Smyth T. The biology of vascular endothelial growth factor. Endocr Rev 18: 4-25, 1997. (Pubitemid 27076453)
    • (1997) Endocrine Reviews , vol.18 , Issue.1 , pp. 4-25
    • Ferrara, N.1    Davis-Smyth, T.2
  • 33
    • 0017284271 scopus 로고
    • Indocyanine green dye fluorescence and infrared absorption choroidal angiography performed simultaneously with fluorescein angiography
    • Flower RW, Hochheimer BF. Indocyanine green dye fluorescence and infrared absorption choroidal angiography performed simultaneously with fluorescein angiography. Johns Hopkins Med J 138: 33-42, 1976.
    • (1976) Johns Hopkins Med J , vol.138 , pp. 33-42
    • Flower, R.W.1    Hochheimer, B.F.2
  • 34
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1: 27-31, 1995.
    • (1995) Nat Med , vol.1 , pp. 27-31
    • Folkman, J.1
  • 35
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 285: 1182-1186, 1971.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 37
    • 0142230995 scopus 로고    scopus 로고
    • In vivo near-infrared fluorescence imaging
    • Frangioni JV. In vivo near-infrared fluorescence imaging. Curr Opin Chem Biol 7: 626-634, 2003.
    • (2003) Curr Opin Chem Biol , vol.7 , pp. 626-634
    • Frangioni, J.V.1
  • 39
    • 2442652873 scopus 로고    scopus 로고
    • Catheter-based in vivo imaging of enzyme activity and gene expression: Feasibility study in mice
    • DOI 10.1148/radiol.2313030831
    • Funovics MA, Weissleder R, Mahmood U. Catheter-based in vivo imaging of enzyme activity and gene expression: feasibility study in mice. Radiology 231: 659-666, 2004. (Pubitemid 38668080)
    • (2004) Radiology , vol.231 , Issue.3 , pp. 659-666
    • Funovics, M.A.1    Weissleder, R.2    Mahmood, U.3
  • 40
    • 35648964095 scopus 로고    scopus 로고
    • Multiparameter noninvasive assessment of treatment susceptibility, drug target inhibition and tumor response guides cancer treatment
    • Gee MS, Upadhyay R, Bergquist H, Weissleder R, Josephson L, Mahmood U. Multiparameter noninvasive assessment of treatment susceptibility, drug target inhibition and tumor response guides cancer treatment. Int J Cancer 121: 2492-2500, 2007.
    • (2007) Int J Cancer , vol.121 , pp. 2492-2500
    • Gee, M.S.1    Upadhyay, R.2    Bergquist, H.3    Weissleder, R.4    Josephson, L.5    Mahmood, U.6
  • 41
    • 33645001286 scopus 로고    scopus 로고
    • Synthesis of fluorescent derivatives of wortmannin and demethoxyviridin as probes for phosphatidylinositol 3-kinase
    • Giner JL, Kehbein KA, Cook JA, Smith MC, Vlahos CJ, Badwey JA. Synthesis of fluorescent derivatives of wortmannin and demethoxyviridin as probes for phosphatidylinositol 3-kinase. Bioorg Med Chem Lett 16: 2518-2521, 2006.
    • (2006) Bioorg Med Chem Lett , vol.16 , pp. 2518-2521
    • Giner, J.L.1    Kehbein, K.A.2    Cook, J.A.3    Smith, M.C.4    Vlahos, C.J.5    Badwey, J.A.6
  • 42
    • 77952712927 scopus 로고    scopus 로고
    • Advances of endomicroscopy for gastrointestinal physiology and diseases
    • Goetz M, Kiesslich R. Advances of endomicroscopy for gastrointestinal physiology and diseases. Am J Physiol Gastrointest Liver Physiol 298: G797-G806, 2010.
    • (2010) Am J Physiol Gastrointest Liver Physiol , vol.298
    • Goetz, M.1    Kiesslich, R.2
  • 43
    • 40549121260 scopus 로고    scopus 로고
    • Confocal endomicroscopy: In vivo diagnosis of neoplastic lesions of the gastrointestinal tract
    • Goetz M, Kiesslich R. Confocal endomicroscopy: in vivo diagnosis of neoplastic lesions of the gastrointestinal tract. Anticancer Res 28: 353-360, 2008.
    • (2008) Anticancer Res , vol.28 , pp. 353-360
    • Goetz, M.1    Kiesslich, R.2
  • 45
    • 12344300543 scopus 로고    scopus 로고
    • Spying on cancer: Molecular imaging in vivo with genetically encoded reporters
    • Gross S, Piwnica-Worms D. Spying on cancer: molecular imaging in vivo with genetically encoded reporters. Cancer Cell 7: 5-15, 2005.
    • (2005) Cancer Cell , vol.7 , pp. 5-15
    • Gross, S.1    Piwnica-Worms, D.2
  • 46
    • 0035496616 scopus 로고    scopus 로고
    • Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2
    • Gupta RA, DuBois RN. Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2. Nat Rev Cancer 1: 11-21, 2001.
    • (2001) Nat Rev Cancer , vol.1 , pp. 11-21
    • Gupta, R.A.1    DuBois, R.N.2
  • 48
    • 19444376167 scopus 로고    scopus 로고
    • Statins and cancer - Beyond the "one drug, one disease" model
    • Hawk E, Viner JL. Statins and cancer - beyond the "one drug, one disease" model. N Engl J Med 352: 2238-2239, 2005.
    • (2005) N Engl J Med , vol.352 , pp. 2238-2239
    • Hawk, E.1    Viner, J.L.2
  • 51
    • 0142209343 scopus 로고    scopus 로고
    • Molecular imaging: Looking at problems, seeing solutions
    • Herschman H. Molecular imaging: looking at problems, seeing solutions. Science 302: 605-608, 2003.
    • (2003) Science , vol.302 , pp. 605-608
    • Herschman, H.1
  • 52
    • 33748474842 scopus 로고    scopus 로고
    • In-vivo imaging of tumor associated urokinase-type plasminogen activator activity
    • Hsiao JK, Law B, Weissleder R, Tung CH. In-vivo imaging of tumor associated urokinase-type plasminogen activator activity. J Biomed Opt 11: 34013, 2006.
    • (2006) J Biomed Opt , vol.11 , pp. 34013
    • Hsiao, J.K.1    Law, B.2    Weissleder, R.3    Tung, C.H.4
  • 54
    • 33750971995 scopus 로고    scopus 로고
    • In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in an orthotopic glioblastoma model
    • Hsu AR, Hou LC, Veeravagu A, Greve JM, Vogel H, Tse V, Chen X. In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in an orthotopic glioblastoma model. Mol Imaging 8: 315-323, 2006.
    • (2006) Mol Imaging , vol.8 , pp. 315-323
    • Hsu, A.R.1    Hou, L.C.2    Veeravagu, A.3    Greve, J.M.4    Vogel, H.5    Tse, V.6    Chen, X.7
  • 55
    • 0034665122 scopus 로고    scopus 로고
    • The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis
    • Jacoby RF, Seibert K, Cole CE, Kelloff GJ, Lubet RA. The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis. Cancer Res 60: 5040-5044, 2000.
    • (2000) Cancer Res , vol.60 , pp. 5040-5044
    • Jacoby, R.F.1    Seibert, K.2    Cole, C.E.3    Kelloff, G.J.4    Lubet, R.A.5
  • 56
    • 33745953240 scopus 로고    scopus 로고
    • Measures of response: RECIST, WHO, and new alternatives
    • Jaffe CC. Measures of response: RECIST, WHO, and new alternatives. J Clin Oncol 24: 3245-3251, 2006.
    • (2006) J Clin Oncol , vol.24 , pp. 3245-3251
    • Jaffe, C.C.1
  • 57
    • 13844265749 scopus 로고    scopus 로고
    • Molecular imaging in the clinical arena
    • Jaffer F, Weissleder R. Molecular imaging in the clinical arena. JAMA 293: 855-862, 2005.
    • (2005) JAMA , vol.293 , pp. 855-862
    • Jaffer, F.1    Weissleder, R.2
  • 58
    • 0034796595 scopus 로고    scopus 로고
    • Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy
    • Jain RK. Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy. Nat Med 7: 987-989, 2001.
    • (2001) Nat Med , vol.7 , pp. 987-989
    • Jain, R.K.1
  • 63
    • 0036790457 scopus 로고    scopus 로고
    • Fluorescence endoscopy using a fluorescein-labeled monoclonal antibody against carcinoembryonic antigen in patients with colorectal carcinoma and adenoma
    • Keller R, Winde G, Terpe HJ, Foerster EC, Domschke W. Fluorescence endoscopy using a fluorescein-labeled monoclonal antibody against carcinoembryonic antigen in patients with colorectal carcinoma and adenoma. Endoscopy 34: 801-807, 2002.
    • (2002) Endoscopy , vol.34 , pp. 801-807
    • Keller, R.1    Winde, G.2    Terpe, H.J.3    Foerster, E.C.4    Domschke, W.5
  • 65
    • 4344679634 scopus 로고    scopus 로고
    • Detection of invasive colon cancer using a novel, targeted, library-derived fluorescent peptide
    • Kelly K, Alencar H, Funovics M, Mahmood U, Weissleder R. Detection of invasive colon cancer using a novel, targeted, library-derived fluorescent peptide. Cancer Res 64: 6247-6251, 2004.
    • (2004) Cancer Res , vol.64 , pp. 6247-6251
    • Kelly, K.1    Alencar, H.2    Funovics, M.3    Mahmood, U.4    Weissleder, R.5
  • 71
    • 0037110469 scopus 로고    scopus 로고
    • Polymorphism G80A in the reduced folate carrier gene and its relationship to methotrexate plasma levels and outcome of childhood acute lymphoblastic leukemia
    • Laverdière C, Chiasson S, Costea I, Moghrabi A, Krajinovic M. Polymorphism G80A in the reduced folate carrier gene and its relationship to methotrexate plasma levels and outcome of childhood acute lymphoblastic leukemia. Blood 100: 3832-3834, 2002.
    • (2002) Blood , vol.100 , pp. 3832-3834
    • Laverdière, C.1    Chiasson, S.2    Costea, I.3    Moghrabi, A.4    Krajinovic, M.5
  • 72
    • 1142306153 scopus 로고    scopus 로고
    • Design, synthesis, and characterization of urokinase plasminogen- activator-sensitive near-infrared reporter
    • Law B, Curino A, Bugge TH, Weissleder R, Tung CH. Design, synthesis, and characterization of urokinase plasminogen-activator-sensitive near-infrared reporter. Chem Biol 11: 99-106, 2004.
    • (2004) Chem Biol , vol.11 , pp. 99-106
    • Law, B.1    Curino, A.2    Bugge, T.H.3    Weissleder, R.4    Tung, C.H.5
  • 73
    • 0034286904 scopus 로고    scopus 로고
    • Hydrophilic cyanine dyes as contrast agents for near-infrared tumor imaging: Synthesis, photophysical properties and spectroscopic in vivo characterization
    • Licha K, Riefke B, Ntziachristos V, Becker A, Chance B, Semmler W. Hydrophilic cyanine dyes as contrast agents for near-infrared tumor imaging: synthesis, photophysical properties and spectroscopic in vivo characterization. Photochem Photobiol 72: 392-398, 2000.
    • (2000) Photochem Photobiol , vol.72 , pp. 392-398
    • Licha, K.1    Riefke, B.2    Ntziachristos, V.3    Becker, A.4    Chance, B.5    Semmler, W.6
  • 74
    • 0038387494 scopus 로고    scopus 로고
    • 5-Fluorouracil: Mechanisms of action and clinical strategies
    • Longley DB, Harkin DP, Johnston PG. 5-Fluorouracil: mechanisms of action and clinical strategies. Nat Rev Cancer 3: 330-338, 2003.
    • (2003) Nat Rev Cancer , vol.3 , pp. 330-338
    • Longley, D.B.1    Harkin, D.P.2    Johnston, P.G.3
  • 78
    • 0036161155 scopus 로고    scopus 로고
    • Detection of dysplastic intestinal adenomas using enzyme-sensing molecular beacons in mice
    • Marten K, Bremer C, Khazaie K, Sameni M, Sloane B, Tung CH, Weissleder R. Detection of dysplastic intestinal adenomas using enzyme-sensing molecular beacons in mice. Gastroenterology 122: 406-414, 2002. (Pubitemid 34116992)
    • (2002) Gastroenterology , vol.122 , Issue.2 , pp. 406-414
    • Marten, K.1    Bremer, C.2    Khazaie, K.3    Sameni, M.4    Sloane, B.5    Tung, C.6    Weissleder, R.7
  • 80
    • 0037338436 scopus 로고    scopus 로고
    • Molecular imaging in living subjects: Seeing fundamental biological processes in a new light
    • Massoud TF, Gambhir SS. Molecular imaging in living subjects: seeing fundamental biological processes in a new light. Genes Dev 17: 545-580, 2003.
    • (2003) Genes Dev , vol.17 , pp. 545-580
    • Massoud, T.F.1    Gambhir, S.S.2
  • 81
    • 59749089432 scopus 로고    scopus 로고
    • Targeted therapy for advanced colorectal cancer-more is not always better
    • Mayer RJ. Targeted therapy for advanced colorectal cancer-more is not always better. N Engl J Med 360: 623-625, 2009.
    • (2009) N Engl J Med , vol.360 , pp. 623-625
    • Mayer, R.J.1
  • 83
    • 13744251436 scopus 로고    scopus 로고
    • Systemic therapy for colorectal cancer
    • Meyerhardt JA, Mayer RJ. Systemic therapy for colorectal cancer. N Engl J Med 352: 476-487, 2005.
    • (2005) N Engl J Med , vol.352 , pp. 476-487
    • Meyerhardt, J.A.1    Mayer, R.J.2
  • 86
  • 87
    • 36549055697 scopus 로고    scopus 로고
    • Will targeted therapy hold its promise? An evidence-based review
    • DOI 10.1097/CCO.0b013e3282f44b12, PII 0000162220080100000016
    • Murdoch D, Sager J. Will targeted therapy hold its promise? An evidence-based review. Curr Opin Oncol 20: 104-111, 2008. (Pubitemid 350190989)
    • (2008) Current Opinion in Oncology , vol.20 , Issue.1 , pp. 104-111
    • Murdoch, D.1    Sager, J.2
  • 88
    • 33748129960 scopus 로고    scopus 로고
    • Fluorescence molecular imaging
    • Ntziachristos V. Fluorescence molecular imaging. Annu Rev Biomed Eng 8: 1-33, 2006.
    • (2006) Annu Rev Biomed Eng , vol.8 , pp. 1-33
    • Ntziachristos, V.1
  • 89
    • 60549118187 scopus 로고    scopus 로고
    • In vivo molecular imaging of cancer with a quenching near-infrared fluorescent probe using conjugates of monoclonal antibodies and indocyanine green
    • Ogawa M, Kosaka N, Choyke PL, Kobayashi H. In vivo molecular imaging of cancer with a quenching near-infrared fluorescent probe using conjugates of monoclonal antibodies and indocyanine green. Cancer Res 69: 1268-1272, 2009.
    • (2009) Cancer Res , vol.69 , pp. 1268-1272
    • Ogawa, M.1    Kosaka, N.2    Choyke, P.L.3    Kobayashi, H.4
  • 90
    • 61849160330 scopus 로고    scopus 로고
    • Tumor-specific detection of an optically targeted antibody combined with a quencher-conjugated neutravidin "quencher-chaser": A dual "quench and chase" strategy to improve target to nontarget ratios for molecular imaging of cancer
    • Ogawa M, Kosaka N, Choyke PL, Kobayashi H. Tumor-specific detection of an optically targeted antibody combined with a quencher-conjugated neutravidin "quencher-chaser": a dual "quench and chase" strategy to improve target to nontarget ratios for molecular imaging of cancer. Bioconjug Chem 20: 147-154, 2009.
    • (2009) Bioconjug Chem , vol.20 , pp. 147-154
    • Ogawa, M.1    Kosaka, N.2    Choyke, P.L.3    Kobayashi, H.4
  • 91
    • 0034600849 scopus 로고    scopus 로고
    • The ErbB signaling network: Receptor heterodimerization in development and cancer
    • Olayioye MA, Neve RM, Lane HA, Hynes NE. The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J 19: 3159-3167, 2000.
    • (2000) EMBO J , vol.19 , pp. 3159-3167
    • Olayioye, M.A.1    Neve, R.M.2    Lane, H.A.3    Hynes, N.E.4
  • 92
    • 63449142391 scopus 로고    scopus 로고
    • Association of progression-free survival, overall survival, and patient-reported outcomes by skin toxicity and KRAS status in patients receiving panitumumab monotherapy
    • Peeters M, Siena S, Van Cutsem E, Sobrero A, Hendlisz A, Cascinu S, Kalofonos H, Devercelli G, Wolf M, Amado RG. Association of progression-free survival, overall survival, and patient-reported outcomes by skin toxicity and KRAS status in patients receiving panitumumab monotherapy. Cancer 115: 1544-1554, 2009.
    • (2009) Cancer , vol.115 , pp. 1544-1554
    • Peeters, M.1    Siena, S.2    Van Cutsem, E.3    Sobrero, A.4    Hendlisz, A.5    Cascinu, S.6    Kalofonos, H.7    Devercelli, G.8    Wolf, M.9    Amado, R.G.10
  • 95
    • 51649111485 scopus 로고    scopus 로고
    • Optical contrast agents and imaging systems for detection and diagnosis of cancer
    • Pierce MC, Javier DJ, Richards-Kortum R. Optical contrast agents and imaging systems for detection and diagnosis of cancer. Int J Cancer 123: 1979-1990, 2008.
    • (2008) Int J Cancer , vol.123 , pp. 1979-1990
    • Pierce, M.C.1    Javier, D.J.2    Richards-Kortum, R.3
  • 96
    • 0032843811 scopus 로고    scopus 로고
    • Estimates of the worldwide mortality from 25 cancers in 1990
    • Pisani P, Parkin DM, Bray F, Ferlay J. Estimates of the worldwide mortality from 25 cancers in 1990. Int J Cancer 83: 18-29, 1999.
    • (1999) Int J Cancer , vol.83 , pp. 18-29
    • Pisani, P.1    Parkin, D.M.2    Bray, F.3    Ferlay, J.4
  • 97
    • 14944368720 scopus 로고    scopus 로고
    • COX-2 inhibitors - Lessons in drug safety
    • Psaty BM, Furberg CD. COX-2 inhibitors - lessons in drug safety. N Engl J Med 352: 1133-1135, 2005.
    • (2005) N Engl J Med , vol.352 , pp. 1133-1135
    • Psaty, B.M.1    Furberg, C.D.2
  • 98
    • 33748160584 scopus 로고    scopus 로고
    • Risks and benefits of celecoxib to prevent recurrent adenomas
    • Psaty BM, Potter JD. Risks and benefits of celecoxib to prevent recurrent adenomas. N Engl J Med 355: 950-952, 2006.
    • (2006) N Engl J Med , vol.355 , pp. 950-952
    • Psaty, B.M.1    Potter, J.D.2
  • 99
    • 77956587025 scopus 로고    scopus 로고
    • Circumstances in which colonoscopy misses cancer
    • Rabeneck L, Paszat L. Circumstances in which colonoscopy misses cancer. Frontline Gastroenterol 1: 52-58, 2010.
    • (2010) Frontline Gastroenterol , vol.1 , pp. 52-58
    • Rabeneck, L.1    Paszat, L.2
  • 101
    • 33846926304 scopus 로고    scopus 로고
    • Fluorescence imaging in vivo: Recent advances
    • DOI 10.1016/j.copbio.2007.01.003, PII S0958166907000043
    • Rao J, Dragulescu-Andrasi A, Yao H. Fluorescence imaging in vivo: recent advances. Curr Opin Biotechnol 18: 17-25, 2007. (Pubitemid 46237739)
    • (2007) Current Opinion in Biotechnology , vol.18 , Issue.1 , pp. 17-25
    • Rao, J.1    Dragulescu-Andrasi, A.2    Yao, H.3
  • 102
    • 0037313516 scopus 로고    scopus 로고
    • Molecular imaging in drug discovery and development
    • DOI 10.1038/nrd1007
    • Rudin M, Weissleder R. Molecular imaging in drug discovery and development. Nat Rev Drug Discov 2: 123-131, 2003. (Pubitemid 37361644)
    • (2003) Nature Reviews Drug Discovery , vol.2 , Issue.2 , pp. 123-131
    • Rudin, M.1    Weissleder, R.2
  • 103
    • 68649116070 scopus 로고    scopus 로고
    • Colorectal cancer treatment: What's next? (or: Is there life after EGFR and VEGF?)
    • Saltz L. Colorectal cancer treatment: what's next? (or: Is there life after EGFR and VEGF?) Gastrointest Cancer Res 2: S20-S22, 2008.
    • (2008) Gastrointest Cancer Res , vol.2
    • Saltz, L.1
  • 105
    • 0035849938 scopus 로고    scopus 로고
    • Recommendation for caution with irinotecan, fluorouracil, and leucovorin for colorectal cancer
    • author reply 146
    • Sargent DJ, Niedzwiecki D, O'Connell MJ, Schilsky RL. Recommendation for caution with irinotecan, fluorouracil, and leucovorin for colorectal cancer. N Engl J Med 345: 144-145; author reply 146, 2001.
    • (2001) N Engl J Med , vol.345 , pp. 144-145
    • Sargent, D.J.1    Niedzwiecki, D.2    O'Connell, M.J.3    Schilsky, R.L.4
  • 107
  • 108
    • 70449864499 scopus 로고    scopus 로고
    • Evaluation and clinically relevant applications of a fluorescent imaging analog to fluorodeoxyglucose positron emission tomography
    • Sheth RA, Josephson L, Mahmood U. Evaluation and clinically relevant applications of a fluorescent imaging analog to fluorodeoxyglucose positron emission tomography. J Biomed Opt 14: 064014, 2009.
    • (2009) J Biomed Opt , vol.14 , pp. 064014
    • Sheth, R.A.1    Josephson, L.2    Mahmood, U.3
  • 109
    • 34547293145 scopus 로고    scopus 로고
    • Real-time multichannel imaging framework for endoscopy, catheters, and fixed geometry intraoperative systems
    • Sheth RA, Upadhyay R, Weissleder R, Mahmood U. Real-time multichannel imaging framework for endoscopy, catheters, and fixed geometry intraoperative systems. Mol Imaging 6: 147-155, 2007.
    • (2007) Mol Imaging , vol.6 , pp. 147-155
    • Sheth, R.A.1    Upadhyay, R.2    Weissleder, R.3    Mahmood, U.4
  • 112
    • 20144365496 scopus 로고    scopus 로고
    • Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention
    • Adenoma Prevention with Celecoxib (APC) Study Investigators
    • Solomon SD, McMurray JJ, Pfeffer MA, Wittes J, Fowler R, Finn P, Anderson WF, Zauber A, Hawk E, Bertagnolli M; Adenoma Prevention with Celecoxib (APC) Study Investigators. Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention. N Engl J Med 352: 1071-1080, 2005.
    • (2005) N Engl J Med , vol.352 , pp. 1071-1080
    • Solomon, S.D.1    McMurray, J.J.2    Pfeffer, M.A.3    Wittes, J.4    Fowler, R.5    Finn, P.6    Anderson, W.F.7    Zauber, A.8    Hawk, E.9    Bertagnolli, M.10
  • 113
    • 0034906359 scopus 로고    scopus 로고
    • Biomarkers for early detection of colon cancer
    • Srivastava S, Verma M, Henson DE. Biomarkers for early detection of colon cancer. Clin Cancer Res 7: 1118-1126, 2001. (Pubitemid 32708660)
    • (2001) Clinical Cancer Research , vol.7 , Issue.5 , pp. 1118-1126
    • Srivastava, S.1    Verma, M.2    Henson, D.E.3
  • 114
    • 0035188727 scopus 로고    scopus 로고
    • How matrix metalloproteinases regulate cell behavior
    • Sternlicht MD, Werb Z. How matrix metalloproteinases regulate cell behavior. Annu Rev Cell Dev Biol 17: 463-516, 2001.
    • (2001) Annu Rev Cell Dev Biol , vol.17 , pp. 463-516
    • Sternlicht, M.D.1    Werb, Z.2
  • 117
    • 35348986522 scopus 로고    scopus 로고
    • Quantitative real-time catheter-based fluorescence molecular imaging in mice
    • DOI 10.1148/radiol.2452061613
    • Upadhyay R, Sheth RA, Weissleder R, Mahmood U. Quantitative real-time catheter-based fluorescence molecular imaging in mice. Radiology 245: 523-531, 2007. (Pubitemid 47612535)
    • (2007) Radiology , vol.245 , Issue.2 , pp. 523-531
    • Upadhyay, R.1    Sheth, R.A.2    Weissleder, R.3    Mahmood, U.4
  • 120
    • 65249148552 scopus 로고    scopus 로고
    • Probe-based confocal laser endomicroscopy
    • Wallace MB, Fockens P. Probe-based confocal laser endomicroscopy. Gastroenterology 136: 1509-1513, 2009.
    • (2009) Gastroenterology , vol.136 , pp. 1509-1513
    • Wallace, M.B.1    Fockens, P.2
  • 121
    • 77951644132 scopus 로고    scopus 로고
    • Advances in endoscopic imaging of colorectal neoplasia
    • Wallace MB, Keisslich R. Advances in endoscopic imaging of colorectal neoplasia. Gastroenterology 138: 2140-2150, 2010.
    • (2010) Gastroenterology , vol.138 , pp. 2140-2150
    • Wallace, M.B.1    Keisslich, R.2
  • 122
    • 0037433450 scopus 로고    scopus 로고
    • Colorectal cancer screening: Scientific review
    • Walsh JME, Terdiman JP. Colorectal cancer screening: scientific review. JAMA 289: 1288-1296, 2003.
    • (2003) JAMA , vol.289 , pp. 1288-1296
    • Walsh, J.M.E.1    Terdiman, J.P.2
  • 124
    • 0037377560 scopus 로고    scopus 로고
    • Decreased expression of the reduced folate carrier and folypolyglutamate synthetase is the basis for acquired resistance to the pemetrexed antifolate (LY231514) in an L1210 murine leukemia cell line
    • Wang Y, Zhao R, Goldman ID. Decreased expression of the reduced folate carrier and folypolyglutamate synthetase is the basis for acquired resistance to the pemetrexed antifolate (LY231514) in an L1210 murine leukemia cell line. Biochem Pharmacol 65: 1163-1170, 2003.
    • (2003) Biochem Pharmacol , vol.65 , pp. 1163-1170
    • Wang, Y.1    Zhao, R.2    Goldman, I.D.3
  • 125
    • 0036359767 scopus 로고    scopus 로고
    • Scaling down imaging: Molecular mapping of cancer in mice
    • Weissleder R. Scaling down imaging: molecular mapping of cancer in mice. Nat Rev Cancer 2: 11-18, 2002. (Pubitemid 37328803)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.1 , pp. 11-18
    • Weissleder, R.1
  • 127
    • 0032951071 scopus 로고    scopus 로고
    • In vivo imaging of tumors with protease-activated near-infrared fluorescent probes
    • DOI 10.1038/7933
    • Weissleder R, Tung CH, Mahmood U, Bogdanov A. In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat Biotechnol 17: 375-378, 1999. (Pubitemid 29166041)
    • (1999) Nature Biotechnology , vol.17 , Issue.4 , pp. 375-378
    • Weissleder, R.1    Tung, C.-H.2    Mahmood, U.3    Bogdanov Jr., A.4
  • 128
    • 42949142609 scopus 로고    scopus 로고
    • Systemic treatment of colorectal cancer
    • Wolpin BM, Mayer RJ. Systemic treatment of colorectal cancer. Gastroenterology 134: 1296-1310, 2008.
    • (2008) Gastroenterology , vol.134 , pp. 1296-1310
    • Wolpin, B.M.1    Mayer, R.J.2
  • 129
    • 33746864082 scopus 로고    scopus 로고
    • 3 expression with Cy7-labeled RGD multimers
    • DOI 10.1007/s11307-006-0041-8
    • Wu Y, Cai W, Chen X. Near-infrared fluorescence imaging of tumor integrin alpha v beta 3 expression with Cy7-labeled RGD multimers. Mol Imaging 8: 226-236, 2006. (Pubitemid 44193419)
    • (2006) Molecular Imaging and Biology , vol.8 , Issue.4 , pp. 226-236
    • Wu, Y.1    Cai, W.2    Chen, X.3
  • 130
    • 4043179911 scopus 로고    scopus 로고
    • In vivo imaging of protease activity in arthritis: A novel approach for monitoring treatment response
    • DOI 10.1002/art.20379
    • Wunder A, Tung CH, Müller-Ladner U, Weissleder R, Mahmood U. In vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response. Arthritis Rheum 50: 2459-2465, 2004. (Pubitemid 39062705)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.8 , pp. 2459-2465
    • Wunder, A.1    Tung, C.-H.2    Muller-Ladner, U.3    Weissleder, R.4    Mahmood, U.5
  • 133
    • 49949090656 scopus 로고    scopus 로고
    • Biochromoendoscopy: Molecular imaging with capsule endoscopy for detection of adenomas of the GI tract
    • Zhang H, Morgan D, Cecil G, Burkholder A, Ramocki N, Scull B, Lund PK. Biochromoendoscopy: molecular imaging with capsule endoscopy for detection of adenomas of the GI tract. Gastrointest Endosc 68: 520-527, 2008.
    • (2008) Gastrointest Endosc , vol.68 , pp. 520-527
    • Zhang, H.1    Morgan, D.2    Cecil, G.3    Burkholder, A.4    Ramocki, N.5    Scull, B.6    Lund, P.K.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.