-
1
-
-
0034996039
-
The role of the plasminogen activation system in angiogenesis and metastasis
-
S. A. Rabbani and A. P. Mazar, "The role of the plasminogen activation system in angiogenesis and metastasis", Surg. Oncol. Clin. N. Am. 10(2), 393-415 (2001). (Pubitemid 32472537)
-
(2001)
Surgical Oncology Clinics of North America
, vol.10
, Issue.2
, pp. 393-415
-
-
Rabbani, S.A.1
Mazar, A.P.2
-
2
-
-
0142188116
-
Urokinase Plasminogen Activator System: A Multifunction Role in Tumor Progression and Metastasis
-
P. F. Choong and A. P. Nadesapillai, "Urokinase plasminogen activator system: a multifunctional role in tumor progression and metastasis", Clin. Orthop. Relat. Res. 415, suppl. S46-58 (2003). (Pubitemid 37323319)
-
(2003)
Clinical Orthopaedics and Related Research
, Issue.415
-
-
Choong, P.F.M.1
Nadesapillai, A.P.W.2
-
3
-
-
0041737535
-
Molecular mechanisms of glioma invasiveness: The role of proteases
-
J. S. Rao, "Molecular mechanisms of glioma invasiveness: the role of proteases", Nat. Rev. Cancer 3(7), 489-501 (2003). (Pubitemid 37328837)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.7
, pp. 489-501
-
-
Rao, J.S.1
-
5
-
-
0030788411
-
The urokinase-type plasminogen activator system in cancer metastasis: A review
-
DOI 10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z
-
P. A. Andreasen, L. Kjoller, L. Christensen, and M. J. Duffy, "The urokinase-type plasminogen activator system in cancer metastasis: a review", Int. J. Cancer 72(1), 1-22 (1997). (Pubitemid 27314632)
-
(1997)
International Journal of Cancer
, vol.72
, Issue.1
, pp. 1-22
-
-
Andreasen, P.A.1
Kjoller, L.2
Christensen, L.3
Duffy, M.J.4
-
6
-
-
2542561906
-
Intra-arterial thrombolysis in acute ischemic stroke: A review of pharmacologic approaches
-
DOI 10.1586/14779072.2.2.285
-
J. A. Pettersen, M. E. Hudon, and M. D. Hill, "Intra-arterial thrombolysis in acute ischemic stroke: a review of pharmacologic approaches", Expert Rev. Cardiovasc. Ther. 2(2), 285-299 (2004). (Pubitemid 38701984)
-
(2004)
Expert Review of Cardiovascular Therapy
, vol.2
, Issue.2
, pp. 285-299
-
-
Pettersen, J.A.1
Hudon, M.E.2
Hill, M.D.3
-
7
-
-
0028158575
-
Receptor-mediated endocytosis of plasminogen activators and activator/inhibitor complexes
-
DOI 10.1016/0014-5793(94)80276-9
-
P. A. Andreasen, L. Sottrup-Jensen, L. Kjoller, A. Nykjaer, S. K. Moestrup, C. M. Petersen, and J. Gliemann, "Receptor-mediated endocytosis of plasminogen activators and activator/inhibitor complexes", FEBS Lett. 338(3), 239-245 (1994). (Pubitemid 24056729)
-
(1994)
FEBS Letters
, vol.338
, Issue.3
, pp. 239-245
-
-
Andreasen, P.A.1
Sottrup-Jensen, L.2
Kjoller, L.3
Nykjaer, A.4
Moestrup, S.K.5
Petersen, C.M.6
Gliemann, J.7
-
8
-
-
0035918882
-
Randomized adjuvant chemotherapy trial in high-risk, lymph node-negative breast cancer patients identified by urokinase-type plasminogen activator and plasminogen activator inhibitor type 1
-
F. Janicke, A. Prechtl, C. Thomssen, N. Harbeck, C. Meisner, M. Untch, C. G. J. F. Sweep, H. K. Selbmann, H. Graeff, and M. Schmitt, "Randomized adjuvant chemotherapy trial in high-risk, lymph node-negative breast cancer patients identified by urokinasetype plasminogen activator and plasminogen activator inhibitor type 1", J. Natl. Cancer Inst. 93(12), 913-920 (2001). (Pubitemid 32624648)
-
(2001)
Journal of the National Cancer Institute
, vol.93
, Issue.12
, pp. 913-920
-
-
Janicke, F.1
Prechtl, A.2
Thomssen, C.3
Harbeck, N.4
Meisner, C.5
Untch, M.6
Sweep, C.G.J.F.7
Selbmann, H.-K.8
Graeff, H.9
Schmitt, M.10
-
9
-
-
0037116616
-
Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients
-
M. P. Look, W. L. J. van Putten, M. J. Duffy, N. Harbeck, I. J. Christensen, C. Thomssen, R. Kates, F. Spyratos, M. Ferno, S. Eppenberger-Castori, C. G. J. F. Sweep, K. Ulm, J. P. Peyrat, P. M. Martin, H. Magdelenat, N. Brunner, C. Duggan, B. W. Lisboa, P. O. Bendahl, V. Quillien, A. Daver, G. Ricolleau, M. E. Meijer-van Gelder, P. Manders, W. E. Fiets, M. A. Blankenstein, P. Broet, S. Romain, G. Daxenbichler, G. Windbichler, T. Cufer, S. Borstnar, W. Kueng, L. V. A. M. Beex, J. G. M. Klijn, N. O'Higgins, U. Eppenberger, F. Janicke, M. Schmitt, and J. A. Foekens, "Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients", J. Natl. Cancer Inst. 94(2), 116-128 (2002). (Pubitemid 34121291)
-
(2002)
Journal of the National Cancer Institute
, vol.94
, Issue.2
, pp. 116-128
-
-
Look, M.P.1
Van Putten, W.L.J.2
Duffy, M.J.3
Harbeck, N.4
Christensen, I.J.5
Thomssen, C.6
Kates, R.7
Spyratos, F.8
Ferno, M.9
Eppenberger-Castori, S.10
Sweep, C.G.J.F.11
Ulm, K.12
Peyrat, J.-P.13
Martin, P.-M.14
Magdelenat, H.15
Brunner, N.16
Duggan, C.17
Lisboa, B.W.18
Bendahl, P.-O.19
Quillien, V.20
Daver, A.21
Ricolleau, G.22
Meijer-Van Gelder, M.E.23
Manders, P.24
Fiets, W.E.25
Blankenstein, M.A.26
Broet, P.27
Romain, S.28
Daxenbichler, G.29
Windbichler, G.30
Cufer, T.31
Borstnar, S.32
Kueng, W.33
Beex, L.V.A.M.34
Klijn, J.G.M.35
O'Higgins, N.36
Eppenberger, U.37
Janicke, F.38
Schmitt, M.39
Foekens, J.A.40
more..
-
10
-
-
2942591963
-
Inhibition of the invasion capacity of carcinoma cells by WX-UK1, a novel synthetic inhibitor of the urokinase-type plasminogen activator system
-
DOI 10.1002/ijc.20192
-
S. Ertongur, S. Lang, B. Mack, K. Wosikowski, B. Muehlenweg, and O. Gires, "Inhibition of the invasion capacity of carcinoma cells by WX-UK1, a novel synthetic inhibitor of the urokinase-type plasminogen activator system", Int. J. Cancer 110(6), 815-824 (2004). (Pubitemid 38758506)
-
(2004)
International Journal of Cancer
, vol.110
, Issue.6
, pp. 815-824
-
-
Ertongur, S.1
Lang, S.2
Mack, B.3
Wosikowski, K.4
Muehlenweg, B.5
Gires, O.6
-
11
-
-
4043153532
-
Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents
-
DOI 10.1074/jbc.M314151200
-
A. Schweinitz, T. Steinmetzer, I. J. Banke, M. J. Arlt, A. Sturzebecher, O. Schuster, A. Geissler, H. Giersiefen, E. Zeslawska, U. Jacob, A. Kruger, and J. Sturzebecher, "Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents", J. Biol. Chem. 279(32), 33613-33622 (2004). (Pubitemid 39063010)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.32
, pp. 33613-33622
-
-
Schweinitz, A.1
Steinmetzer, T.2
Banke, I.J.3
Arlt, M.J.E.4
Sturzebecher, A.5
Schuster, O.6
Geissler, A.7
Giersiefen, H.8
Zeslawska, E.9
Jacob, U.10
Kruger, A.11
Sturzebecher, J.12
-
12
-
-
0038208347
-
The protease inhibitor bikunin, a novel anti-metastatic agent
-
DOI 10.1515/BC.2003.083
-
H. Kobayashi, M. Suzuki, Y. Hirashima, and T. Terao, "The protease inhibitor bikunin, a novel anti-metastatic agent", Biol. Chem. 384(5), 749-754 (2003). (Pubitemid 36747936)
-
(2003)
Biological Chemistry
, vol.384
, Issue.5
, pp. 749-754
-
-
Kobayashi, H.1
Suzuki, M.2
Hirashima, Y.3
Terao, T.4
-
13
-
-
0042783126
-
Inhibition of the tumor-associated urokinase-type plasminogen activation system: Effects of high-level synthesis of soluble urokinase receptor in ovarian and breast cancer cells in vitro and in vivo
-
V. Magdolen, A. Kruger, S. Sato, J. Nagel, S. Sperl, U. Reuning, P. Rettenberger, U. Magdolen, and M. Schmitt, "Inhibition of the tumor-associated urokinase-type plasminogen activation system: effects of high-level synthesis of soluble urokinase receptor in ovarian and breast cancer cells in vitro and in vivo", Recent Results Cancer Res. 162, 43-63 (2003).
-
(2003)
Recent Results Cancer Res.
, vol.162
, pp. 43-63
-
-
Magdolen, V.1
Kruger, A.2
Sato, S.3
Nagel, J.4
Sperl, S.5
Reuning, U.6
Rettenberger, P.7
Magdolen, U.8
Schmitt, M.9
-
14
-
-
1542679984
-
Protease sensors for bioimaging
-
DOI 10.1007/s00216-003-2199-0
-
M. Funovics, R. Weissleder, and C. H. Tung, "Protease sensors for bioimaging", Anal. Bioanal. Chem. 377(6), 956-963 (2003). (Pubitemid 40877826)
-
(2003)
Analytical and Bioanalytical Chemistry
, vol.377
, Issue.6
, pp. 956-963
-
-
Funovics, M.1
Weissleder, R.2
Tung, C.-H.3
-
15
-
-
1142306153
-
Design, Synthesis, and Characterization of Urokinase Plasminogen- Activator- Sensitive Near-Infrared Reporter
-
DOI 10.1016/S1074-5521(03)00296-5
-
B. Law, A. Curino, T. H. Bugge, R. Weissleder, and C. H. Tung, "Design, synthesis, and characterization of urokinase plasminogenactivator- sensitive near-infrared reporter", Chem. Biol. 11(1), 99-106 (2004). (Pubitemid 38203994)
-
(2004)
Chemistry and Biology
, vol.11
, Issue.1
, pp. 99-106
-
-
Law, B.1
Curino, A.2
Bugge, T.H.3
Weissleder, R.4
Tung, C.-H.5
-
16
-
-
0031760355
-
The amount and proteolytic content of vesicles shed by human cancer cell lines correlates with their in vitro invasiveness
-
A. Ginestra, M. D. La Placa, F. Saladino, D. Cassara, H. Nagase, and M. L. Vittorelli, "The amount and proteolytic content of vesicles shed by human cancer cell lines correlates with their in vitro invasiveness", Anticancer Res. 18(5A), 3433-3437 (1998). (Pubitemid 28546471)
-
(1998)
Anticancer Research
, vol.18
, Issue.5
, pp. 3433-3437
-
-
Ginestra, A.1
La Placa, M.D.2
Saladino, F.3
Cassara, D.4
Nagase, H.5
Vittorelli, M.L.6
-
17
-
-
13644263240
-
Optical zymography for specific detection of urokinase plasminogen activator activity in biological samples
-
DOI 10.1016/j.ab.2004.11.039
-
B. Law, J. K. Hsiao, T. H. Bugge, R. Weissleder, and C. H. Tung, "Novel optical zymography for specific detection of urokinase plasminogen activator in biological samples", Anal. Biochem. 338(1), 151-158 (2005). (Pubitemid 40228908)
-
(2005)
Analytical Biochemistry
, vol.338
, Issue.1
, pp. 151-158
-
-
Law, B.1
Hsiao, J.-K.2
Bugge, T.H.3
Weissleder, R.4
Tung, C.-H.5
-
18
-
-
0032697682
-
Near-infrared optical imaging of protease activity for tumor detection
-
U. Mahmood, C. H. Tung, A. Bogdanov, Jr., and R. Weissleder, "Near-infrared optical imaging of protease activity for tumor detection", Radiology 213(3), 866-870 (1999).
-
(1999)
Radiology
, vol.213
, Issue.3
, pp. 866-870
-
-
Mahmood, U.1
Tung, C.H.2
Bogdanov Jr., A.3
Weissleder, R.4
-
19
-
-
0027408681
-
The role of the urokinase receptor in extracellular matrix degradation by HT29 human colon carcinoma cells
-
DOI 10.1002/ijc.2910530316
-
L. S. Reiter, E. K. Kruithof, J. F. Cajot, and B. Sordat, "The role of the urokinase receptor in extracellular matrix degradation by HT29 human colon carcinoma cells", Int. J. Cancer 53(3), 444-450 (1993). (Pubitemid 23047893)
-
(1993)
International Journal of Cancer
, vol.53
, Issue.3
, pp. 444-450
-
-
Reiter, L.S.1
Kruithof, E.K.O.2
Cajot, J.-F.3
Sordat, B.4
-
20
-
-
0030916499
-
Urokinase and the urokinase receptor: Association with in vitro invasiveness of human bladder cancer cell lines
-
M. A. Hudson and L. M. McReynolds, "Urokinase and the urokinase receptor: association with in vitro invasiveness of human bladder cancer cell lines", J. Natl. Cancer Inst. 89(10), 709-717 (1997). (Pubitemid 27229859)
-
(1997)
Journal of the National Cancer Institute
, vol.89
, Issue.10
, pp. 709-717
-
-
Hudson, M.A.1
McReynolds, L.M.2
-
21
-
-
0034933664
-
The urokinase plasminogen activator receptor (uPAR) as a target for the diagnosis and therapy of cancer
-
DOI 10.1097/00001813-200106000-00001
-
A. P. Mazar, "The urokinase plasminogen activator receptor (uPAR) as a target for the diagnosis and therapy of cancer", Anti-Cancer Drugs 12(5), 387-400 (2001). (Pubitemid 32643084)
-
(2001)
Anti-Cancer Drugs
, vol.12
, Issue.5
, pp. 387-400
-
-
Mazar, A.P.1
-
22
-
-
0034760321
-
Optical imaging of matrix metalloproteinase-2 activity in tumors: Feasibility study in a mouse model
-
C. Bremer, S. Bredow, U. Mahmood, R. Weissleder, and C. H. Tung, "Optical imaging of matrix metalloproteinase-2 activity in tumors: feasibility study in a mouse model", Radiology 221(2), 523-529 (2001). (Pubitemid 33043440)
-
(2001)
Radiology
, vol.221
, Issue.2
, pp. 523-529
-
-
Bremer, C.1
Bredow, S.2
Mahmood, U.3
Weissleder, R.4
Tung, C.-H.5
-
23
-
-
0032951071
-
In vivo imaging of tumors with protease-activated near-infrared fluorescent probes
-
DOI 10.1038/7933
-
R. Weissleder, C. H. Tung, U. Mahmood, and A. Bogdanov, Jr., "In vivo imaging of tumors with protease-activated near-infrared fluorescent probes", Nat. Biotechnol. 17(4), 375-378 (1999). (Pubitemid 29166041)
-
(1999)
Nature Biotechnology
, vol.17
, Issue.4
, pp. 375-378
-
-
Weissleder, R.1
Tung, C.-H.2
Mahmood, U.3
Bogdanov Jr., A.4
-
24
-
-
0034283034
-
In vivo imaging of proteolytic enzyme activity using a novel molecular reporter
-
C. H. Tung, U. Mahmood, S. Bredow, and R. Weissleder, "In vivo imaging of proteolytic enzyme activity using a novel molecular reporter", Cancer Res. 60(17), 4953-4958 (2000).
-
(2000)
Cancer Res.
, vol.60
, Issue.17
, pp. 4953-4958
-
-
Tung, C.H.1
Mahmood, U.2
Bredow, S.3
Weissleder, R.4
-
25
-
-
9144270498
-
Fluorescent peptide probes for in vivo diagnostic imaging
-
C. H. Tung, "Fluorescent peptide probes for in vivo diagnostic imaging", Biopolymers 76(5), 391-403 (2004).
-
(2004)
Biopolymers
, vol.76
, Issue.5
, pp. 391-403
-
-
Tung, C.H.1
-
26
-
-
0028228422
-
The state of differentiation of HT-29 colon carcinoma cells alters the secretion of cathepsin D and of plasminogen activator
-
DOI 10.1002/ijc.2910570617
-
G. Huet, F. Zerimech, M. C. Dieu, B. Hemon, G. Grard, M. Balduyck, A. Janin, R. Lafyatis, and P. Degand, "The state of differentiation of HT-29 colon carcinoma cells alters the secretion of cathepsin D and of plasminogen activator", Int. J. Cancer 57(6), 875-882 (1994). (Pubitemid 24216825)
-
(1994)
International Journal of Cancer
, vol.57
, Issue.6
, pp. 875-882
-
-
Huet, G.1
Zerimech, F.2
Dieu, M.-C.3
Hemon, B.4
Grard, G.5
Balduyck, M.6
Janin, A.7
Lafyatis, R.8
Degand, P.9
-
27
-
-
0034667385
-
Tumor development is retarded in mice lacking the gene for urokinase-type plasminogen activator or its inhibitor, plasminogen activator inhibitor-1
-
L. S. Gutierrez, A. Schulman, T. Brito-Robinson, F. Noria, V. A. Ploplis, and F. J. Castellino, "Tumor development is retarded in mice lacking the gene for urokinase-type plasminogen activator or its inhibitor, plasminogen activator inhibitor-1", Cancer Res. 60(20), 5839-5847 (2000).
-
(2000)
Cancer Res.
, vol.60
, Issue.20
, pp. 5839-5847
-
-
Gutierrez, L.S.1
Schulman, A.2
Brito-Robinson, T.3
Noria, F.4
Ploplis, V.A.5
Castellino, F.J.6
-
28
-
-
2442652873
-
Catheter-based in vivo imaging of enzyme activity and gene expression: Feasibility study in mice
-
DOI 10.1148/radiol.2313030831
-
M. A. Funovics, R. Weissleder, and U. Mahmood, "Catheter-based in vivo imaging of enzyme activity and gene expression: Feasibility study in mice", Radiology 231(3), 659-666 (2004). (Pubitemid 38668080)
-
(2004)
Radiology
, vol.231
, Issue.3
, pp. 659-666
-
-
Funovics, M.A.1
Weissleder, R.2
Mahmood, U.3
|