Epigenetic inactivation of the tumor suppressor gene RIZ1 in hepatocellular carcinoma involves both DNA methylation and histone modifications

Journal of Hepatology

Volumn 53, Issue 5, 2010, Pages 889-895

  Zhang, Cuijuan ^a   Li, Hiuming ^b   Wang, Yan ^a   Liu, Wenjun ^a   Zhang, Qinghui ^a   Zhang, Tingguo ^a   Zhang, Xiaoying ^a   Han, Bo ^a   Zhou, Gengyin ^a  

^a SHANDONG UNIVERSITY   (China)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Hepatocellular carcinoma; Histone acetylation; Histone methylation; Hypermethylation; RIZ1

Indexed keywords

5 AZA 2 DEOXYCITIDINE; HISTONE; HISTONE DEACETYLASE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 3; HISTONE DEACETYLASE INHIBITOR; HISTONE H3; TRIAZINE DERIVATIVE; TRICHOSTATIN A; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; GENE EXPRESSION; GENE INACTIVATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CELL CARCINOMA; METHYLATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RIZ1 GENE; TUMOR SUPPRESSOR GENE;

ACETYLATION; AZACITIDINE; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; DNA METHYLATION; DNA-BINDING PROTEINS; EPIGENESIS, GENETIC; GENES, TUMOR SUPPRESSOR; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; HYDROXAMIC ACIDS; LIVER NEOPLASMS; NUCLEAR PROTEINS; PROMOTER REGIONS, GENETIC; RNA, MESSENGER; TRANSCRIPTION FACTORS;

EID: 77957340047     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2010.05.012     Document Type: Article

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