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Volumn 184, Issue C, 2010, Pages 265-294

Neural grafting in Parkinson's disease. Problems and possibilities

Author keywords

Dopamine neuron; Dyskinesias; Lewy bodies; Parkinson's disease; Stem cells; Transplantation

Indexed keywords

BOOK; CLINICAL TRIAL; DONOR; DOPAMINERGIC NERVE CELL; DYSKINESIA; EMBRYONIC STEM CELL; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; NERVE CELL; NERVE GRAFT; NEUROPATHOLOGY; NONHUMAN; PARKINSON DISEASE; PATIENT SELECTION; PRIORITY JOURNAL; STEM CELL; SURGICAL TECHNIQUE; TISSUE PREPARATION; TREATMENT OUTCOME;

EID: 77957230012     PISSN: 00796123     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0079-6123(10)84014-2     Document Type: Chapter
Times cited : (110)

References (172)
  • 1
    • 77954622035 scopus 로고    scopus 로고
    • Cell transplantation in Parkinson's disease: Problems and perspectives
    • Allan L.E., Petit G.H., Brundin P. Cell transplantation in Parkinson's disease: Problems and perspectives. Current Opinion in Neurology 2010, 23(4):426-432.
    • (2010) Current Opinion in Neurology , vol.23 , Issue.4 , pp. 426-432
    • Allan, L.E.1    Petit, G.H.2    Brundin, P.3
  • 3
    • 61449171881 scopus 로고    scopus 로고
    • Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient
    • Amariglio N., Hirshberg A., Scheithauer B.W., Cohen Y., Loewenthal R., Trakhtenbrot L., et al. Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient. PLoS Medicine 2009, 6(2):e1000029.
    • (2009) PLoS Medicine , vol.6 , Issue.2
    • Amariglio, N.1    Hirshberg, A.2    Scheithauer, B.W.3    Cohen, Y.4    Loewenthal, R.5    Trakhtenbrot, L.6
  • 4
    • 0034669082 scopus 로고    scopus 로고
    • Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture
    • Amit M., Carpenter M.K., Inokuma M.S., Chiu C.P., Harris C.P., Waknitz M.A., et al. Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture. Developmental Biology 2000, 227(2):271-278.
    • (2000) Developmental Biology , vol.227 , Issue.2 , pp. 271-278
    • Amit, M.1    Carpenter, M.K.2    Inokuma, M.S.3    Chiu, C.P.4    Harris, C.P.5    Waknitz, M.A.6
  • 5
    • 33947691631 scopus 로고    scopus 로고
    • Gene expression changes in long term expanded human neural progenitor cells passaged by chopping lead to loss of neurogenic potential in vivo
    • Anderson L., Burnstein R.M., He X., Luce R., Furlong R., Foltynie T., et al. Gene expression changes in long term expanded human neural progenitor cells passaged by chopping lead to loss of neurogenic potential in vivo. Experimental Neurology 2007, 204(2):512-524.
    • (2007) Experimental Neurology , vol.204 , Issue.2 , pp. 512-524
    • Anderson, L.1    Burnstein, R.M.2    He, X.3    Luce, R.4    Furlong, R.5    Foltynie, T.6
  • 6
    • 33749570292 scopus 로고    scopus 로고
    • Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease
    • Anderson J.P., Walker D.E., Goldstein J.M., de Laat R., Banducci K., Caccavello R.J., et al. Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease. Journal of Biological Chemistry 2006, 281(40):29739-29752.
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.40 , pp. 29739-29752
    • Anderson, J.P.1    Walker, D.E.2    Goldstein, J.M.3    de Laat, R.4    Banducci, K.5    Caccavello, R.J.6
  • 7
    • 33947206784 scopus 로고    scopus 로고
    • Ngn2 and Nurr1 act in synergy to induce midbrain dopaminergic neurons from expanded neural stem and progenitor cells
    • Andersson E.K., Irvin D.K., Ahlsio J., Parmar M. Ngn2 and Nurr1 act in synergy to induce midbrain dopaminergic neurons from expanded neural stem and progenitor cells. Experimental Cell Research 2007, 313(6):1172-1180.
    • (2007) Experimental Cell Research , vol.313 , Issue.6 , pp. 1172-1180
    • Andersson, E.K.1    Irvin, D.K.2    Ahlsio, J.3    Parmar, M.4
  • 8
    • 31044445499 scopus 로고    scopus 로고
    • Identification of intrinsic determinants of midbrain dopamine neurons
    • Andersson E., Tryggvason U., Deng Q., Friling S., Alekseenko Z., Robert B., et al. Identification of intrinsic determinants of midbrain dopamine neurons. Cell 2006, 124(2):393-405.
    • (2006) Cell , vol.124 , Issue.2 , pp. 393-405
    • Andersson, E.1    Tryggvason, U.2    Deng, Q.3    Friling, S.4    Alekseenko, Z.5    Robert, B.6
  • 9
    • 0031905828 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor improves intrastriatal graft survival of stored dopaminergic cells
    • Apostolides C., Sanford E., Hong M., Mendez I. Glial cell line-derived neurotrophic factor improves intrastriatal graft survival of stored dopaminergic cells. Neuroscience 1998, 83(2):363-372.
    • (1998) Neuroscience , vol.83 , Issue.2 , pp. 363-372
    • Apostolides, C.1    Sanford, E.2    Hong, M.3    Mendez, I.4
  • 11
    • 0027319917 scopus 로고
    • The biology and behaviour of intracerebral adrenal transplants in animals and man
    • Barker R., Dunnett S. The biology and behaviour of intracerebral adrenal transplants in animals and man. Reviews Neuroscience 1993, 4(2):113-146.
    • (1993) Reviews Neuroscience , vol.4 , Issue.2 , pp. 113-146
    • Barker, R.1    Dunnett, S.2
  • 12
    • 18444373622 scopus 로고    scopus 로고
    • Immune problems in central nervous system cell therapy
    • Barker R.A., Widner H. Immune problems in central nervous system cell therapy. NeuroRx 2004, 1(4):472-481.
    • (2004) NeuroRx , vol.1 , Issue.4 , pp. 472-481
    • Barker, R.A.1    Widner, H.2
  • 14
    • 0028104614 scopus 로고
    • Ethical guidelines for the use of human embryonic or fetal tissue for experimental and clinical neurotransplantation and research. Network of European CNS Transplantation and Restoration (NECTAR)
    • Boer G.J. Ethical guidelines for the use of human embryonic or fetal tissue for experimental and clinical neurotransplantation and research. Network of European CNS Transplantation and Restoration (NECTAR). Journal of Neurology 1994, 242(1):1-13.
    • (1994) Journal of Neurology , vol.242 , Issue.1 , pp. 1-13
    • Boer, G.J.1
  • 15
    • 46749154758 scopus 로고    scopus 로고
    • Identification of midbrain floor plate radial glia-like cells as dopaminergic progenitors
    • Bonilla S., Hall A.C., Pinto L., Attardo A., Gotz M., Huttner W.B., et al. Identification of midbrain floor plate radial glia-like cells as dopaminergic progenitors. Glia 2008, 56(8):809-820.
    • (2008) Glia , vol.56 , Issue.8 , pp. 809-820
    • Bonilla, S.1    Hall, A.C.2    Pinto, L.3    Attardo, A.4    Gotz, M.5    Huttner, W.B.6
  • 17
    • 0021358883 scopus 로고
    • Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines
    • Bradley A., Evans M., Kaufman M.H., Robertson E. Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines. Nature 1984, 309(5965):255-256.
    • (1984) Nature , vol.309 , Issue.5965 , pp. 255-256
    • Bradley, A.1    Evans, M.2    Kaufman, M.H.3    Robertson, E.4
  • 18
    • 33745542454 scopus 로고    scopus 로고
    • Transplantation of human embryonic stem cell-derived cells to a rat model of Parkinson's disease: Effect of in vitro differentiation on graft survival and teratoma formation
    • Brederlau A., Correia A.S., Anisimov S.V., Elmi M., Paul G., Roybon L., et al. Transplantation of human embryonic stem cell-derived cells to a rat model of Parkinson's disease: Effect of in vitro differentiation on graft survival and teratoma formation. Stem Cells 2006, 24(6):1433-1440.
    • (2006) Stem Cells , vol.24 , Issue.6 , pp. 1433-1440
    • Brederlau, A.1    Correia, A.S.2    Anisimov, S.V.3    Elmi, M.4    Paul, G.5    Roybon, L.6
  • 19
    • 0023933288 scopus 로고
    • Survival and function of dissociated rat dopamine neurones grafted at different developmental stages or after being cultured in vitro
    • Brundin P., Barbin G., Strecker R.E., Isacson O., Prochiantz A., Bjorklund A. Survival and function of dissociated rat dopamine neurones grafted at different developmental stages or after being cultured in vitro. Brain Research 1988, 467(2):233-243.
    • (1988) Brain Research , vol.467 , Issue.2 , pp. 233-243
    • Brundin, P.1    Barbin, G.2    Strecker, R.E.3    Isacson, O.4    Prochiantz, A.5    Bjorklund, A.6
  • 20
  • 22
    • 77949848854 scopus 로고    scopus 로고
    • Prion-like transmission of protein aggregates in neurodegenerative diseases
    • Brundin P., Melki R., Kopito R. Prion-like transmission of protein aggregates in neurodegenerative diseases. Nature Reviews Molecular Cell Biology 2010, 11(4):301-307.
    • (2010) Nature Reviews Molecular Cell Biology , vol.11 , Issue.4 , pp. 301-307
    • Brundin, P.1    Melki, R.2    Kopito, R.3
  • 24
    • 0033934144 scopus 로고    scopus 로고
    • Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease
    • Brundin P., Pogarell O., Hagell P., Piccini P., Widner H., Schrag A., et al. Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease. Brain 2000, 123(Pt 7):1380-1390.
    • (2000) Brain , vol.123 , Issue.PART 7 , pp. 1380-1390
    • Brundin, P.1    Pogarell, O.2    Hagell, P.3    Piccini, P.4    Widner, H.5    Schrag, A.6
  • 25
    • 0029240724 scopus 로고
    • Neuroepithelial progenitor cells explanted from human fetal brain proliferate and differentiate in vitro
    • Buc-Caron M.H. Neuroepithelial progenitor cells explanted from human fetal brain proliferate and differentiate in vitro. Neurobiology of Disease 1995, 2(1):37-47.
    • (1995) Neurobiology of Disease , vol.2 , Issue.1 , pp. 37-47
    • Buc-Caron, M.H.1
  • 26
    • 1842477467 scopus 로고    scopus 로고
    • Karyotype of human ES cells during extended culture
    • author reply 382
    • Buzzard J.J., Gough N.M., Crook J.M., Colman A. Karyotype of human ES cells during extended culture. Nature Biotechnology 2004, 22(4):381-382. author reply 382.
    • (2004) Nature Biotechnology , vol.22 , Issue.4 , pp. 381-382
    • Buzzard, J.J.1    Gough, N.M.2    Crook, J.M.3    Colman, A.4
  • 27
    • 59849099441 scopus 로고    scopus 로고
    • The role of Lmx1a in the differentiation of human embryonic stem cells into midbrain dopamine neurons in culture and after transplantation into a Parkinson's disease model
    • Cai J., Donaldson A., Yang M., German M.S., Enikolopov G., Iacovitti L. The role of Lmx1a in the differentiation of human embryonic stem cells into midbrain dopamine neurons in culture and after transplantation into a Parkinson's disease model. Stem Cells 2009, 27(1):220-229.
    • (2009) Stem Cells , vol.27 , Issue.1 , pp. 220-229
    • Cai, J.1    Donaldson, A.2    Yang, M.3    German, M.S.4    Enikolopov, G.5    Iacovitti, L.6
  • 28
    • 77954932494 scopus 로고    scopus 로고
    • Dopaminergic neurons derived from human induced pluripotent stem cells survive and integrate into 6-OHDA lesioned rats
    • Cai J., Yang M., Poremsky E., Kidd S., Schneider J.S., Iacovitti L. Dopaminergic neurons derived from human induced pluripotent stem cells survive and integrate into 6-OHDA lesioned rats. Stem Cells and Development 2010, 19(7):1017-1023.
    • (2010) Stem Cells and Development , vol.19 , Issue.7 , pp. 1017-1023
    • Cai, J.1    Yang, M.2    Poremsky, E.3    Kidd, S.4    Schneider, J.S.5    Iacovitti, L.6
  • 29
    • 0035023474 scopus 로고    scopus 로고
    • Growth factors regulate the survival and fate of cells derived from human neurospheres
    • Caldwell M.A., He X., Wilkie N., Pollack S., Marshall G., Wafford K.A., et al. Growth factors regulate the survival and fate of cells derived from human neurospheres. Nature Biotechnology 2001, 19(5):475-479.
    • (2001) Nature Biotechnology , vol.19 , Issue.5 , pp. 475-479
    • Caldwell, M.A.1    He, X.2    Wilkie, N.3    Pollack, S.4    Marshall, G.5    Wafford, K.A.6
  • 30
    • 0031843933 scopus 로고    scopus 로고
    • Heparin, but not other proteoglycans, potentiates the mitogenic effects of FGF-2 on mesencephalic precursor cells
    • Caldwell M.A., Svendsen C.N. Heparin, but not other proteoglycans, potentiates the mitogenic effects of FGF-2 on mesencephalic precursor cells. Experimental Neurology 1998, 152(1):1-10.
    • (1998) Experimental Neurology , vol.152 , Issue.1 , pp. 1-10
    • Caldwell, M.A.1    Svendsen, C.N.2
  • 31
    • 34547484764 scopus 로고    scopus 로고
    • Serotonin neuron transplants exacerbate L-DOPA-induced dyskinesias in a rat model of Parkinson's disease
    • Carlsson T., Carta M., Winkler C., Bjorklund A., Kirik D. Serotonin neuron transplants exacerbate L-DOPA-induced dyskinesias in a rat model of Parkinson's disease. Journal of Neuroscience 2007, 27(30):8011-8022.
    • (2007) Journal of Neuroscience , vol.27 , Issue.30 , pp. 8011-8022
    • Carlsson, T.1    Carta, M.2    Winkler, C.3    Bjorklund, A.4    Kirik, D.5
  • 32
    • 33244459813 scopus 로고    scopus 로고
    • Graft placement and uneven pattern of reinnervation in the striatum is important for development of graft-induced dyskinesia
    • Carlsson T., Winkler C., Lundblad M., Cenci M.A., Bjorklund A., Kirik D. Graft placement and uneven pattern of reinnervation in the striatum is important for development of graft-induced dyskinesia. Neurobiology of Disease 2006, 21(3):657-668.
    • (2006) Neurobiology of Disease , vol.21 , Issue.3 , pp. 657-668
    • Carlsson, T.1    Winkler, C.2    Lundblad, M.3    Cenci, M.A.4    Bjorklund, A.5    Kirik, D.6
  • 33
    • 34447627504 scopus 로고    scopus 로고
    • Dopamine released from 5-HT terminals is the cause of L-DOPA-induced dyskinesia in parkinsonian rats
    • Carta M., Carlsson T., Kirik D., Bjorklund A. Dopamine released from 5-HT terminals is the cause of L-DOPA-induced dyskinesia in parkinsonian rats. Brain 2007, 130(Pt 7):1819-1833.
    • (2007) Brain , vol.130 , Issue.PART 7 , pp. 1819-1833
    • Carta, M.1    Carlsson, T.2    Kirik, D.3    Bjorklund, A.4
  • 34
    • 77953394342 scopus 로고    scopus 로고
    • Role of serotonin neurons in the induction of levodopa- and graft-induced dyskinesias in Parkinson's disease
    • Carta M., Carlsson T., Munoz A., Kirik D., Bjorklund A. Role of serotonin neurons in the induction of levodopa- and graft-induced dyskinesias in Parkinson's disease. Movement Disorder 2010, 25(Suppl. 1):S174-S179.
    • (2010) Movement Disorder , vol.25 , Issue.SUPPL. 1
    • Carta, M.1    Carlsson, T.2    Munoz, A.3    Kirik, D.4    Bjorklund, A.5
  • 35
    • 0033913626 scopus 로고    scopus 로고
    • FK506 and cyclosporin A enhance the survival of cultured and grafted rat embryonic dopamine neurons
    • Castilho R.F., Hansson O., Brundin P. FK506 and cyclosporin A enhance the survival of cultured and grafted rat embryonic dopamine neurons. Experimental Neurology 2000, 164(1):94-101.
    • (2000) Experimental Neurology , vol.164 , Issue.1 , pp. 94-101
    • Castilho, R.F.1    Hansson, O.2    Brundin, P.3
  • 37
    • 33846974346 scopus 로고    scopus 로고
    • Large stem cell grafts could lead to erroneous interpretations of behavioral results?
    • ; author reply 118-119
    • Christophersen N.S., Brundin P. Large stem cell grafts could lead to erroneous interpretations of behavioral results?. Nature Medicine 2007, 13(2):118. ; author reply 118-119.
    • (2007) Nature Medicine , vol.13 , Issue.2 , pp. 118
    • Christophersen, N.S.1    Brundin, P.2
  • 38
    • 33751118534 scopus 로고    scopus 로고
    • Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease?
    • Chu Y., Kordower J.H. Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease?. Neurobiology of Disease 2007, 25(1):134-149.
    • (2007) Neurobiology of Disease , vol.25 , Issue.1 , pp. 134-149
    • Chu, Y.1    Kordower, J.H.2
  • 40
    • 33747587820 scopus 로고    scopus 로고
    • Neural precursors derived from embryonic stem cells, but not those from fetal ventral mesencephalon, maintain the potential to differentiate into dopaminergic neurons after expansion in vitro
    • Chung S., Shin B.S., Hwang M., Lardaro T., Kang U.J., Isacson O., et al. Neural precursors derived from embryonic stem cells, but not those from fetal ventral mesencephalon, maintain the potential to differentiate into dopaminergic neurons after expansion in vitro. Stem Cells 2006, 24(6):1583-1593.
    • (2006) Stem Cells , vol.24 , Issue.6 , pp. 1583-1593
    • Chung, S.1    Shin, B.S.2    Hwang, M.3    Lardaro, T.4    Kang, U.J.5    Isacson, O.6
  • 41
    • 0032556063 scopus 로고    scopus 로고
    • Strands of embryonic mesencephalic tissue show greater dopamine neuron survival and better behavioral improvement than cell suspensions after transplantation in parkinsonian rats
    • Clarkson E.D., Zawada W.M., Adams F.S., Bell K.P., Freed C.R. Strands of embryonic mesencephalic tissue show greater dopamine neuron survival and better behavioral improvement than cell suspensions after transplantation in parkinsonian rats. Brain Research 1998, 806(1):60-68.
    • (1998) Brain Research , vol.806 , Issue.1 , pp. 60-68
    • Clarkson, E.D.1    Zawada, W.M.2    Adams, F.S.3    Bell, K.P.4    Freed, C.R.5
  • 42
    • 0035124066 scopus 로고    scopus 로고
    • IGF-I and bFGF improve dopamine neuron survival and behavioral outcome in parkinsonian rats receiving cultured human fetal tissue strands
    • Clarkson E.D., Zawada W.M., Bell K.P., Esplen J.E., Choi P.K., Heidenreich K.A., et al. IGF-I and bFGF improve dopamine neuron survival and behavioral outcome in parkinsonian rats receiving cultured human fetal tissue strands. Experimental Neurology 2001, 168(1):183-191.
    • (2001) Experimental Neurology , vol.168 , Issue.1 , pp. 183-191
    • Clarkson, E.D.1    Zawada, W.M.2    Bell, K.P.3    Esplen, J.E.4    Choi, P.K.5    Heidenreich, K.A.6
  • 43
  • 44
    • 62949103656 scopus 로고    scopus 로고
    • Fibroblast growth factor-20 increases the yield of midbrain dopaminergic neurons derived from human embryonic stem cells
    • Correia A.S., Anisimov S.V., Roybon L., Li J.Y., Brundin P. Fibroblast growth factor-20 increases the yield of midbrain dopaminergic neurons derived from human embryonic stem cells. Frontiers in Neuroanatomy 2007, 1:4.
    • (2007) Frontiers in Neuroanatomy , vol.1 , pp. 4
    • Correia, A.S.1    Anisimov, S.V.2    Roybon, L.3    Li, J.Y.4    Brundin, P.5
  • 47
    • 0029047361 scopus 로고
    • Temporal pattern of host responses against intrastriatal grafts of syngeneic, allogeneic or xenogeneic embryonic neuronal tissue in rats
    • Duan W.M., Widner H., Brundin P. Temporal pattern of host responses against intrastriatal grafts of syngeneic, allogeneic or xenogeneic embryonic neuronal tissue in rats. Experimental Brain Research 1995, 104(2):227-242.
    • (1995) Experimental Brain Research , vol.104 , Issue.2 , pp. 227-242
    • Duan, W.M.1    Widner, H.2    Brundin, P.3
  • 48
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • Evans M.J., Kaufman M.H. Establishment in culture of pluripotential cells from mouse embryos. Nature 1981, 292(5819):154-156.
    • (1981) Nature , vol.292 , Issue.5819 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 49
    • 0036169364 scopus 로고    scopus 로고
    • The heterogeneity of idiopathic Parkinson's disease
    • Foltynie T., Brayne C., Barker R.A. The heterogeneity of idiopathic Parkinson's disease. Journal of Neurology 2002, 249(2):138-145.
    • (2002) Journal of Neurology , vol.249 , Issue.2 , pp. 138-145
    • Foltynie, T.1    Brayne, C.2    Barker, R.A.3
  • 50
    • 0026443974 scopus 로고
    • Survival of implanted fetal dopamine cells and neurologic improvement 12 to 46 months after transplantation for Parkinson's disease
    • Freed C.R., Breeze R.E., Rosenberg N.L., Schneck S.A., Kriek E., Qi J.X., et al. Survival of implanted fetal dopamine cells and neurologic improvement 12 to 46 months after transplantation for Parkinson's disease. New England Journal of Medicine 1992, 327(22):1549-1555.
    • (1992) New England Journal of Medicine , vol.327 , Issue.22 , pp. 1549-1555
    • Freed, C.R.1    Breeze, R.E.2    Rosenberg, N.L.3    Schneck, S.A.4    Kriek, E.5    Qi, J.X.6
  • 52
    • 84870533673 scopus 로고    scopus 로고
    • Important aspects of surgical methodology for transplantation in Parkinson's disease
    • Springer Science Business Media B.V, Berlin, P. Brundin, C.W. Olanow (Eds.)
    • Freeman T.F., Brundin P. Important aspects of surgical methodology for transplantation in Parkinson's disease. Restorative therapies in Parkinson's disease (pp. 131-165). 2006, Springer Science Business Media B.V, Berlin. P. Brundin, C.W. Olanow (Eds.).
    • (2006) Restorative therapies in Parkinson's disease (pp. 131-165).
    • Freeman, T.F.1    Brundin, P.2
  • 53
  • 54
    • 0033565709 scopus 로고    scopus 로고
    • Site-specific migration and neuronal differentiation of human neural progenitor cells after transplantation in the adult rat brain
    • Fricker R.A., Carpenter M.K., Winkler C., Greco C., Gates M.A., Bjorklund A. Site-specific migration and neuronal differentiation of human neural progenitor cells after transplantation in the adult rat brain. Journal of Neuroscience 1999, 19(14):5990-6005.
    • (1999) Journal of Neuroscience , vol.19 , Issue.14 , pp. 5990-6005
    • Fricker, R.A.1    Carpenter, M.K.2    Winkler, C.3    Greco, C.4    Gates, M.A.5    Bjorklund, A.6
  • 55
    • 0028229549 scopus 로고
    • Human embryonic dopamine neurons xenografted to the rat: Effects of cryopreservation and varying regional source of donor cells on transplant survival, morphology and function
    • Frodl E.M., Duan W.M., Sauer H., Kupsch A., Brundin P. Human embryonic dopamine neurons xenografted to the rat: Effects of cryopreservation and varying regional source of donor cells on transplant survival, morphology and function. Brain Research 1994, 647(2):286-298.
    • (1994) Brain Research , vol.647 , Issue.2 , pp. 286-298
    • Frodl, E.M.1    Duan, W.M.2    Sauer, H.3    Kupsch, A.4    Brundin, P.5
  • 56
    • 0034712047 scopus 로고    scopus 로고
    • Mammalian neural stem cells
    • Gage F.H. Mammalian neural stem cells. Science 2000, 287(5457):1433-1438.
    • (2000) Science , vol.287 , Issue.5457 , pp. 1433-1438
    • Gage, F.H.1
  • 57
    • 0029817315 scopus 로고    scopus 로고
    • Lazaroid treatment prevents death of cultured rat embryonic mesencephalic neurons following glutathione depletion
    • Grasbon-Frodl E.M., Andersson A., Brundin P. Lazaroid treatment prevents death of cultured rat embryonic mesencephalic neurons following glutathione depletion. Journal of Neurochemistry 1996, 67(4):1653-1660.
    • (1996) Journal of Neurochemistry , vol.67 , Issue.4 , pp. 1653-1660
    • Grasbon-Frodl, E.M.1    Andersson, A.2    Brundin, P.3
  • 58
    • 77249086109 scopus 로고    scopus 로고
    • The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson's disease
    • Grealish S., Jonsson M.E., Li M., Kirik D., Bjorklund A., Thompson L.H. The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson's disease. Brain 2010, 133(Pt 2):482-495.
    • (2010) Brain , vol.133 , Issue.PART 2 , pp. 482-495
    • Grealish, S.1    Jonsson, M.E.2    Li, M.3    Kirik, D.4    Bjorklund, A.5    Thompson, L.H.6
  • 59
    • 70449532484 scopus 로고    scopus 로고
    • A stable proportion of Lewy body bearing neurons in the substantia nigra suggests a model in which the Lewy body causes neuronal death
    • Greffard S., Verny M., Bonnet A.M., Seilhean D., Hauw J.J., Duyckaerts C. A stable proportion of Lewy body bearing neurons in the substantia nigra suggests a model in which the Lewy body causes neuronal death. Neurobiology of Aging 2010, 31(1):99-103.
    • (2010) Neurobiology of Aging , vol.31 , Issue.1 , pp. 99-103
    • Greffard, S.1    Verny, M.2    Bonnet, A.M.3    Seilhean, D.4    Hauw, J.J.5    Duyckaerts, C.6
  • 60
    • 0024578633 scopus 로고
    • Fetal brain transplantation for Parkinson's disease: Technique for obtaining donor tissue
    • Gustavii B. Fetal brain transplantation for Parkinson's disease: Technique for obtaining donor tissue. Lancet 1989, 1(8637):565.
    • (1989) Lancet , vol.1 , Issue.8637 , pp. 565
    • Gustavii, B.1
  • 61
    • 0034921374 scopus 로고    scopus 로고
    • Cell survival and clinical outcome following intrastriatal transplantation in Parkinson disease
    • Hagell P., Brundin P. Cell survival and clinical outcome following intrastriatal transplantation in Parkinson disease. Journal of Neuropathology and Experimental Neurology 2001, 60(8):741-752.
    • (2001) Journal of Neuropathology and Experimental Neurology , vol.60 , Issue.8 , pp. 741-752
    • Hagell, P.1    Brundin, P.2
  • 62
    • 28144432547 scopus 로고    scopus 로고
    • Dyskinesias and dopamine cell replacement in Parkinson's disease: A clinical perspective
    • Hagell P., Cenci M.A. Dyskinesias and dopamine cell replacement in Parkinson's disease: A clinical perspective. Brain Research Bulletin 2005, 68(1-2):4-15.
    • (2005) Brain Research Bulletin , vol.68 , Issue.1-2 , pp. 4-15
    • Hagell, P.1    Cenci, M.A.2
  • 64
    • 0032692348 scopus 로고    scopus 로고
    • Sequential bilateral transplantation in Parkinson's disease: Effects of the second graft
    • Hagell P., Schrag A., Piccini P., Jahanshahi M., Brown R., Rehncrona S., et al. Sequential bilateral transplantation in Parkinson's disease: Effects of the second graft. Brain 1999, 122(Pt 6):1121-1132.
    • (1999) Brain , vol.122 , Issue.PART 6 , pp. 1121-1132
    • Hagell, P.1    Schrag, A.2    Piccini, P.3    Jahanshahi, M.4    Brown, R.5    Rehncrona, S.6
  • 66
    • 70449625586 scopus 로고    scopus 로고
    • Dopamine neuron precursors within the developing human mesencephalon show radial glial characteristics
    • Hebsgaard J.B., Nelander J., Sabelstrom H., Jonsson M.E., Stott S., Parmar M. Dopamine neuron precursors within the developing human mesencephalon show radial glial characteristics. Glia 2009, 57(15):1648-1658.
    • (2009) Glia , vol.57 , Issue.15 , pp. 1648-1658
    • Hebsgaard, J.B.1    Nelander, J.2    Sabelstrom, H.3    Jonsson, M.E.4    Stott, S.5    Parmar, M.6
  • 67
    • 34247590317 scopus 로고    scopus 로고
    • Selection of embryonic stem cell-derived enhanced green fluorescent protein-positive dopamine neurons using the tyrosine hydroxylase promoter is confounded by reporter gene expression in immature cell populations
    • Hedlund E., Pruszak J., Ferree A., Vinuela A., Hong S., Isacson O., et al. Selection of embryonic stem cell-derived enhanced green fluorescent protein-positive dopamine neurons using the tyrosine hydroxylase promoter is confounded by reporter gene expression in immature cell populations. Stem Cells 2007, 25(5):1126-1135.
    • (2007) Stem Cells , vol.25 , Issue.5 , pp. 1126-1135
    • Hedlund, E.1    Pruszak, J.2    Ferree, A.3    Vinuela, A.4    Hong, S.5    Isacson, O.6
  • 68
    • 48649111174 scopus 로고    scopus 로고
    • Embryonic stem cell-derived Pitx3-enhanced green fluorescent protein midbrain dopamine neurons survive enrichment by fluorescence-activated cell sorting and function in an animal model of Parkinson's disease
    • Hedlund E., Pruszak J., Lardaro T., Ludwig W., Vinuela A., Kim K.S., et al. Embryonic stem cell-derived Pitx3-enhanced green fluorescent protein midbrain dopamine neurons survive enrichment by fluorescence-activated cell sorting and function in an animal model of Parkinson's disease. Stem Cells 2008, 26(6):1526-1536.
    • (2008) Stem Cells , vol.26 , Issue.6 , pp. 1526-1536
    • Hedlund, E.1    Pruszak, J.2    Lardaro, T.3    Ludwig, W.4    Vinuela, A.5    Kim, K.S.6
  • 69
    • 37349128901 scopus 로고    scopus 로고
    • Neural precursors derived from human embryonic stem cells maintain long-term proliferation without losing the potential to differentiate into all three neural lineages, including dopaminergic neurons
    • Hong S., Kang U.J., Isacson O., Kim K.S. Neural precursors derived from human embryonic stem cells maintain long-term proliferation without losing the potential to differentiate into all three neural lineages, including dopaminergic neurons. Journal of Neurochemistry 2008, 104(2):316-324.
    • (2008) Journal of Neurochemistry , vol.104 , Issue.2 , pp. 316-324
    • Hong, S.1    Kang, U.J.2    Isacson, O.3    Kim, K.S.4
  • 70
    • 69849090592 scopus 로고    scopus 로고
    • Intrajejunal levodopa infusion in Parkinson's disease: A pilot multicenter study of effects on nonmotor symptoms and quality of life
    • Honig H., Antonini A., Martinez-Martin P., Forgacs I., Faye G.C., Fox T., et al. Intrajejunal levodopa infusion in Parkinson's disease: A pilot multicenter study of effects on nonmotor symptoms and quality of life. Movement Disorder 2009, 24(10):1468-1474.
    • (2009) Movement Disorder , vol.24 , Issue.10 , pp. 1468-1474
    • Honig, H.1    Antonini, A.2    Martinez-Martin, P.3    Forgacs, I.4    Faye, G.C.5    Fox, T.6
  • 72
    • 0036209085 scopus 로고    scopus 로고
    • The accuracy of diagnosis of parkinsonian syndromes in a specialist movement disorder service
    • Hughes A.J., Daniel S.E., Ben-Shlomo Y., Lees A.J. The accuracy of diagnosis of parkinsonian syndromes in a specialist movement disorder service. Brain 2002, 125(Pt 4):861-870.
    • (2002) Brain , vol.125 , Issue.PART 4 , pp. 861-870
    • Hughes, A.J.1    Daniel, S.E.2    Ben-Shlomo, Y.3    Lees, A.J.4
  • 73
    • 34249891596 scopus 로고    scopus 로고
    • GDNF in Parkinson disease: An object lesson in the tyranny of type II
    • Hutchinson M., Gurney S., Newson R. GDNF in Parkinson disease: An object lesson in the tyranny of type II. Journal of Neuroscience Methods 2007, 163(2):190-192.
    • (2007) Journal of Neuroscience Methods , vol.163 , Issue.2 , pp. 190-192
    • Hutchinson, M.1    Gurney, S.2    Newson, R.3
  • 74
    • 33845277826 scopus 로고    scopus 로고
    • A protocol for the differentiation of human embryonic stem cells into dopaminergic neurons using only chemically defined human additives: Studies in vitro and in vivo
    • Iacovitti L., Donaldson A.E., Marshall C.E., Suon S., Yang M. A protocol for the differentiation of human embryonic stem cells into dopaminergic neurons using only chemically defined human additives: Studies in vitro and in vivo. Brain Research 2007, 1127(1):19-25.
    • (2007) Brain Research , vol.1127 , Issue.1 , pp. 19-25
    • Iacovitti, L.1    Donaldson, A.E.2    Marshall, C.E.3    Suon, S.4    Yang, M.5
  • 76
    • 64749111225 scopus 로고    scopus 로고
    • Virus-free induction of pluripotency and subsequent excision of reprogramming factors
    • Kaji K., Norrby K., Paca A., Mileikovsky M., Mohseni P., Woltjen K. Virus-free induction of pluripotency and subsequent excision of reprogramming factors. Nature 2009, 458(7239):771-775.
    • (2009) Nature , vol.458 , Issue.7239 , pp. 771-775
    • Kaji, K.1    Norrby, K.2    Paca, A.3    Mileikovsky, M.4    Mohseni, P.5    Woltjen, K.6
  • 77
    • 33244496187 scopus 로고    scopus 로고
    • Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons
    • Kele J., Simplicio N., Ferri A.L., Mira H., Guillemot F., Arenas E., et al. Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons. Development 2006, 133(3):495-505.
    • (2006) Development , vol.133 , Issue.3 , pp. 495-505
    • Kele, J.1    Simplicio, N.2    Ferri, A.L.3    Mira, H.4    Guillemot, F.5    Arenas, E.6
  • 78
    • 0036469897 scopus 로고    scopus 로고
    • Neurogenesis in embryos and in adult neural stem cells
    • Kintner C. Neurogenesis in embryos and in adult neural stem cells. Journal of Neuroscience 2002, 22(3):639-643.
    • (2002) Journal of Neuroscience , vol.22 , Issue.3 , pp. 639-643
    • Kintner, C.1
  • 79
    • 35448952847 scopus 로고    scopus 로고
    • Human embryonic stem cell-derived neural precursors as a continuous, stable, and on-demand source for human dopamine neurons
    • Ko J.Y., Park C.H., Koh H.C., Cho Y.H., Kyhm J.H., Kim Y.S., et al. Human embryonic stem cell-derived neural precursors as a continuous, stable, and on-demand source for human dopamine neurons. Journal of Neurochemistry 2007, 103(4):1417-1429.
    • (2007) Journal of Neurochemistry , vol.103 , Issue.4 , pp. 1417-1429
    • Ko, J.Y.1    Park, C.H.2    Koh, H.C.3    Cho, Y.H.4    Kyhm, J.H.5    Kim, Y.S.6
  • 80
    • 43249114934 scopus 로고    scopus 로고
    • Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease
    • Kordower J.H., Chu Y., Hauser R.A., Freeman T.B., Olanow C.W. Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease. Nature Medicine 2008, 14(5):504-506.
    • (2008) Nature Medicine , vol.14 , Issue.5 , pp. 504-506
    • Kordower, J.H.1    Chu, Y.2    Hauser, R.A.3    Freeman, T.B.4    Olanow, C.W.5
  • 81
    • 61449216234 scopus 로고    scopus 로고
    • Transplanted dopaminergic neurons develop PD pathologic changes: A second case report
    • Kordower J.H., Chu Y., Hauser R.A., Olanow C.W., Freeman T.B. Transplanted dopaminergic neurons develop PD pathologic changes: A second case report. Movement Disorder 2008, 23(16):2303-2306.
    • (2008) Movement Disorder , vol.23 , Issue.16 , pp. 2303-2306
    • Kordower, J.H.1    Chu, Y.2    Hauser, R.A.3    Olanow, C.W.4    Freeman, T.B.5
  • 82
    • 8944230650 scopus 로고    scopus 로고
    • Functional fetal nigral grafts in a patient with Parkinson's disease: Chemoanatomic, ultrastructural, and metabolic studies
    • Kordower J.H., Rosenstein J.M., Collier T.J., Burke M.A., Chen E.Y., Li J.M., et al. Functional fetal nigral grafts in a patient with Parkinson's disease: Chemoanatomic, ultrastructural, and metabolic studies. Journal of Comparative Neurology 1996, 370(2):203-230.
    • (1996) Journal of Comparative Neurology , vol.370 , Issue.2 , pp. 203-230
    • Kordower, J.H.1    Rosenstein, J.M.2    Collier, T.J.3    Burke, M.A.4    Chen, E.Y.5    Li, J.M.6
  • 84
    • 67349211457 scopus 로고    scopus 로고
    • Amphetamine-induced abnormal movements occur independently of both transplant- and host-derived serotonin innervation following neural grafting in a rat model of Parkinson's disease
    • Lane E.L., Brundin P., Cenci M.A. Amphetamine-induced abnormal movements occur independently of both transplant- and host-derived serotonin innervation following neural grafting in a rat model of Parkinson's disease. Neurobiology of Disease 2009, 35(1):42-51.
    • (2009) Neurobiology of Disease , vol.35 , Issue.1 , pp. 42-51
    • Lane, E.L.1    Brundin, P.2    Cenci, M.A.3
  • 85
    • 53749099718 scopus 로고    scopus 로고
    • Neuroinflammation in the generation of post-transplantation dyskinesia in Parkinson's disease
    • Lane E.L., Soulet D., Vercammen L., Cenci M.A., Brundin P. Neuroinflammation in the generation of post-transplantation dyskinesia in Parkinson's disease. Neurobiology of Disease 2008, 32(2):220-228.
    • (2008) Neurobiology of Disease , vol.32 , Issue.2 , pp. 220-228
    • Lane, E.L.1    Soulet, D.2    Vercammen, L.3    Cenci, M.A.4    Brundin, P.5
  • 86
    • 68549099660 scopus 로고    scopus 로고
    • Priming for L-DOPA-induced abnormal involuntary movements increases the severity of amphetamine-induced dyskinesia in grafted rats
    • Lane E.L., Vercammen L., Cenci M.A., Brundin P. Priming for L-DOPA-induced abnormal involuntary movements increases the severity of amphetamine-induced dyskinesia in grafted rats. Experimental Neurology 2009, 219(1):355-358.
    • (2009) Experimental Neurology , vol.219 , Issue.1 , pp. 355-358
    • Lane, E.L.1    Vercammen, L.2    Cenci, M.A.3    Brundin, P.4
  • 87
    • 33646140789 scopus 로고    scopus 로고
    • The impact of graft size on the development of dyskinesia following intrastriatal grafting of embryonic dopamine neurons in the rat
    • Lane E.L., Winkler C., Brundin P., Cenci M.A. The impact of graft size on the development of dyskinesia following intrastriatal grafting of embryonic dopamine neurons in the rat. Neurobiology of Disease 2006, 22(2):334-345.
    • (2006) Neurobiology of Disease , vol.22 , Issue.2 , pp. 334-345
    • Lane, E.L.1    Winkler, C.2    Brundin, P.3    Cenci, M.A.4
  • 88
    • 1942520420 scopus 로고    scopus 로고
    • Challenges in Parkinson's disease: Restoration of the nigrostriatal dopamine system is not enough
    • Lang A.E., Obeso J.A. Challenges in Parkinson's disease: Restoration of the nigrostriatal dopamine system is not enough. Lancet Neurology 2004, 3(5):309-316.
    • (2004) Lancet Neurology , vol.3 , Issue.5 , pp. 309-316
    • Lang, A.E.1    Obeso, J.A.2
  • 90
    • 77950552036 scopus 로고    scopus 로고
    • Foxa2 and Nurr1 synergistically yield A9 nigral dopamine neurons exhibiting improved differentiation, function, and cell survival
    • Lee H.S., Bae E.J., Yi S.H., Shim J.W., Jo A.Y., Kang J.S., et al. Foxa2 and Nurr1 synergistically yield A9 nigral dopamine neurons exhibiting improved differentiation, function, and cell survival. Stem Cells 2010, 28(3):501-512.
    • (2010) Stem Cells , vol.28 , Issue.3 , pp. 501-512
    • Lee, H.S.1    Bae, E.J.2    Yi, S.H.3    Shim, J.W.4    Jo, A.Y.5    Kang, J.S.6
  • 93
    • 39949083205 scopus 로고    scopus 로고
    • Critical issues of clinical human embryonic stem cell therapy for brain repair
    • Li J.Y., Christophersen N.S., Hall V., Soulet D., Brundin P. Critical issues of clinical human embryonic stem cell therapy for brain repair. Trends in Neurosciences 2008, 31(3):146-153.
    • (2008) Trends in Neurosciences , vol.31 , Issue.3 , pp. 146-153
    • Li, J.Y.1    Christophersen, N.S.2    Hall, V.3    Soulet, D.4    Brundin, P.5
  • 94
    • 43249110200 scopus 로고    scopus 로고
    • Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
    • Li J.Y., Englund E., Holton J.L., Soulet D., Hagell P., Lees A.J., et al. Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation. Nature Medicine 2008, 14(5):501-503.
    • (2008) Nature Medicine , vol.14 , Issue.5 , pp. 501-503
    • Li, J.Y.1    Englund, E.2    Holton, J.L.3    Soulet, D.4    Hagell, P.5    Lees, A.J.6
  • 95
    • 77949820437 scopus 로고    scopus 로고
    • Characterization of Lewy body pathology in 12- and 16-year old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease
    • Li J.Y., Englund E., Widner H., Rehncrona S., Bjorklund A., Lindvall O., et al. Characterization of Lewy body pathology in 12- and 16-year old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease. Movement Disorder 2010, 25(8):1091-1096.
    • (2010) Movement Disorder , vol.25 , Issue.8 , pp. 1091-1096
    • Li, J.Y.1    Englund, E.2    Widner, H.3    Rehncrona, S.4    Bjorklund, A.5    Lindvall, O.6
  • 96
    • 0025058215 scopus 로고
    • Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease
    • Lindvall O., Brundin P., Widner H., Rehncrona S., Gustavii B., Frackowiak R., et al. Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease. Science 1990, 247(4942):574-577.
    • (1990) Science , vol.247 , Issue.4942 , pp. 574-577
    • Lindvall, O.1    Brundin, P.2    Widner, H.3    Rehncrona, S.4    Gustavii, B.5    Frackowiak, R.6
  • 97
    • 0024362054 scopus 로고
    • Human fetal dopamine neurons grafted into the striatum in two patients with severe Parkinson's disease. A detailed account of methodology and a 6-month follow-up
    • Lindvall O., Rehncrona S., Brundin P., Gustavii B., Astedt B., Widner H., et al. Human fetal dopamine neurons grafted into the striatum in two patients with severe Parkinson's disease. A detailed account of methodology and a 6-month follow-up. Archives of Neurology 1989, 46(6):615-631.
    • (1989) Archives of Neurology , vol.46 , Issue.6 , pp. 615-631
    • Lindvall, O.1    Rehncrona, S.2    Brundin, P.3    Gustavii, B.4    Astedt, B.5    Widner, H.6
  • 98
    • 0027977759 scopus 로고
    • Evidence for long-term survival and function of dopaminergic grafts in progressive Parkinson's disease
    • Lindvall O., Sawle G., Widner H., Rothwell J.C., Bjorklund A., Brooks D., et al. Evidence for long-term survival and function of dopaminergic grafts in progressive Parkinson's disease. Annals of Neurology 1994, 35(2):172-180.
    • (1994) Annals of Neurology , vol.35 , Issue.2 , pp. 172-180
    • Lindvall, O.1    Sawle, G.2    Widner, H.3    Rothwell, J.C.4    Bjorklund, A.5    Brooks, D.6
  • 99
    • 0026551551 scopus 로고
    • Levodopa-induced dyskinesias in Parkinson's disease: Clinical and pharmacological classification
    • Luquin M.R., Scipioni O., Vaamonde J., Gershanik O., Obeso J.A. Levodopa-induced dyskinesias in Parkinson's disease: Clinical and pharmacological classification. Movement Disorder 1992, 7(2):117-124.
    • (1992) Movement Disorder , vol.7 , Issue.2 , pp. 117-124
    • Luquin, M.R.1    Scipioni, O.2    Vaamonde, J.3    Gershanik, O.4    Obeso, J.A.5
  • 101
    • 0036830588 scopus 로고    scopus 로고
    • Dyskinesia after fetal cell transplantation for parkinsonism: A PET study
    • Ma Y., Feigin A., Dhawan V., Fukuda M., Shi Q., Greene P., et al. Dyskinesia after fetal cell transplantation for parkinsonism: A PET study. Annals of Neurology 2002, 52(5):628-634.
    • (2002) Annals of Neurology , vol.52 , Issue.5 , pp. 628-634
    • Ma, Y.1    Feigin, A.2    Dhawan, V.3    Fukuda, M.4    Shi, Q.5    Greene, P.6
  • 102
    • 75149140104 scopus 로고    scopus 로고
    • Dopamine cell implantation in Parkinson's disease: Long-term clinical and (18)F-FDOPA PET outcomes
    • Ma Y., Tang C., Chaly T., Greene P., Breeze R., Fahn S., et al. Dopamine cell implantation in Parkinson's disease: Long-term clinical and (18)F-FDOPA PET outcomes. Journal of Nuclear Medicine 2010, 51(1):7-15.
    • (2010) Journal of Nuclear Medicine , vol.51 , Issue.1 , pp. 7-15
    • Ma, Y.1    Tang, C.2    Chaly, T.3    Greene, P.4    Breeze, R.5    Fahn, S.6
  • 103
    • 0023835638 scopus 로고
    • Transplantation of fetal substantia nigra and adrenal medulla to the caudate nucleus in two patients with Parkinson's disease
    • Madrazo I., Leon V., Torres C., Aguilera M.C., Varela G., Alvarez F., et al. Transplantation of fetal substantia nigra and adrenal medulla to the caudate nucleus in two patients with Parkinson's disease. New England Journal of Medicine 1988, 318(1):51.
    • (1988) New England Journal of Medicine , vol.318 , Issue.1 , pp. 51
    • Madrazo, I.1    Leon, V.2    Torres, C.3    Aguilera, M.C.4    Varela, G.5    Alvarez, F.6
  • 105
    • 0001007610 scopus 로고
    • Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
    • Martin G.R. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proceedings of the National Academy of Sciences of the United States of America 1981, 78(12):7634-7638.
    • (1981) Proceedings of the National Academy of Sciences of the United States of America , vol.78 , Issue.12 , pp. 7634-7638
    • Martin, G.R.1
  • 107
    • 20444376889 scopus 로고    scopus 로고
    • Pitx3 regulates tyrosine hydroxylase expression in the substantia nigra and identifies a subgroup of mesencephalic dopaminergic progenitor neurons during mouse development
    • Maxwell S.L., Ho H.Y., Kuehner E., Zhao S., Li M. Pitx3 regulates tyrosine hydroxylase expression in the substantia nigra and identifies a subgroup of mesencephalic dopaminergic progenitor neurons during mouse development. Developmental Biology 2005, 282(2):467-479.
    • (2005) Developmental Biology , vol.282 , Issue.2 , pp. 467-479
    • Maxwell, S.L.1    Ho, H.Y.2    Kuehner, E.3    Zhao, S.4    Li, M.5
  • 108
    • 0034099045 scopus 로고    scopus 로고
    • Enhancement of survival of stored dopaminergic cells and promotion of graft survival by exposure of human fetal nigral tissue to glial cell line-derived neurotrophic factor in patients with Parkinson's disease. Report of two cases and technical considerations
    • Mendez I., Dagher A., Hong M., Hebb A., Gaudet P., Law A., et al. Enhancement of survival of stored dopaminergic cells and promotion of graft survival by exposure of human fetal nigral tissue to glial cell line-derived neurotrophic factor in patients with Parkinson's disease. Report of two cases and technical considerations. Journal of Neurosurgery 2000, 92(5):863-869.
    • (2000) Journal of Neurosurgery , vol.92 , Issue.5 , pp. 863-869
    • Mendez, I.1    Dagher, A.2    Hong, M.3    Hebb, A.4    Gaudet, P.5    Law, A.6
  • 109
    • 43249085326 scopus 로고    scopus 로고
    • Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years
    • Mendez I., Vinuela A., Astradsson A., Mukhida K., Hallett P., Robertson H., et al. Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years. Nature Medicine 2008, 14(5):507-509.
    • (2008) Nature Medicine , vol.14 , Issue.5 , pp. 507-509
    • Mendez, I.1    Vinuela, A.2    Astradsson, A.3    Mukhida, K.4    Hallett, P.5    Robertson, H.6
  • 110
    • 70350711981 scopus 로고    scopus 로고
    • Organization of the human embryonic ventral mesencephalon
    • Nelander J., Hebsgaard J.B., Parmar M. Organization of the human embryonic ventral mesencephalon. Gene Expression Patterns 2009, 9(8):555-561.
    • (2009) Gene Expression Patterns , vol.9 , Issue.8 , pp. 555-561
    • Nelander, J.1    Hebsgaard, J.B.2    Parmar, M.3
  • 111
    • 33847689843 scopus 로고    scopus 로고
    • A method for single-cell sorting and expansion of genetically modified human embryonic stem cells
    • Nicholas C.R., Gaur M., Wang S., Pera R.A., Leavitt A.D. A method for single-cell sorting and expansion of genetically modified human embryonic stem cells. Stem Cells and Development 2007, 16(1):109-117.
    • (2007) Stem Cells and Development , vol.16 , Issue.1 , pp. 109-117
    • Nicholas, C.R.1    Gaur, M.2    Wang, S.3    Pera, R.A.4    Leavitt, A.D.5
  • 112
    • 66049117813 scopus 로고    scopus 로고
    • Naive and primed pluripotent states
    • Nichols J., Smith A. Naive and primed pluripotent states. Cell Stem Cell 2009, 4(6):487-492.
    • (2009) Cell Stem Cell , vol.4 , Issue.6 , pp. 487-492
    • Nichols, J.1    Smith, A.2
  • 113
    • 0029153487 scopus 로고
    • Preservation of fetal ventral mesencephalic cells by cool storage: In-vitro viability and TH-positive neuron survival after microtransplantation to the striatum
    • Nikkhah G., Eberhard J., Olsson M., Bjorklund A. Preservation of fetal ventral mesencephalic cells by cool storage: In-vitro viability and TH-positive neuron survival after microtransplantation to the striatum. Brain Research 1995, 687(1-2):22-34.
    • (1995) Brain Research , vol.687 , Issue.1-2 , pp. 22-34
    • Nikkhah, G.1    Eberhard, J.2    Olsson, M.3    Bjorklund, A.4
  • 115
    • 77749320143 scopus 로고    scopus 로고
    • Generation of mouse-induced pluripotent stem cells with plasmid vectors
    • Okita K., Hong H., Takahashi K., Yamanaka S. Generation of mouse-induced pluripotent stem cells with plasmid vectors. Nature Protocols 2010, 5(3):418-428.
    • (2010) Nature Protocols , vol.5 , Issue.3 , pp. 418-428
    • Okita, K.1    Hong, H.2    Takahashi, K.3    Yamanaka, S.4
  • 116
    • 0035850021 scopus 로고    scopus 로고
    • Transplantation of embryonic dopamine neurons for severe Parkinson's disease
    • author reply 147
    • Olanow C.W., Freeman T., Kordower J. Transplantation of embryonic dopamine neurons for severe Parkinson's disease. New England Journal of Medicine 2001, 345(2):146. author reply 147.
    • (2001) New England Journal of Medicine , vol.345 , Issue.2 , pp. 146
    • Olanow, C.W.1    Freeman, T.2    Kordower, J.3
  • 117
    • 0042837887 scopus 로고    scopus 로고
    • A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease
    • Olanow C.W., Goetz C.G., Kordower J.H., Stoessl A.J., Sossi V., Brin M.F., et al. A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease. Annals of Neurology 2003, 54(3):403-414.
    • (2003) Annals of Neurology , vol.54 , Issue.3 , pp. 403-414
    • Olanow, C.W.1    Goetz, C.G.2    Kordower, J.H.3    Stoessl, A.J.4    Sossi, V.5    Brin, M.F.6
  • 118
    • 72949111183 scopus 로고    scopus 로고
    • Dopaminergic transplantation for Parkinson's disease: Current status and future prospects
    • Olanow C.W., Kordower J.H., Lang A.E., Obeso J.A. Dopaminergic transplantation for Parkinson's disease: Current status and future prospects. Annals of Neurology 2009, 66(5):591-596.
    • (2009) Annals of Neurology , vol.66 , Issue.5 , pp. 591-596
    • Olanow, C.W.1    Kordower, J.H.2    Lang, A.E.3    Obeso, J.A.4
  • 119
    • 34848896595 scopus 로고    scopus 로고
    • Differences in neurogenic potential in floor plate cells along an anteroposterior location: Midbrain dopaminergic neurons originate from mesencephalic floor plate cells
    • Ono Y., Nakatani T., Sakamoto Y., Mizuhara E., Minaki Y., Kumai M., et al. Differences in neurogenic potential in floor plate cells along an anteroposterior location: Midbrain dopaminergic neurons originate from mesencephalic floor plate cells. Development 2007, 134(17):3213-3225.
    • (2007) Development , vol.134 , Issue.17 , pp. 3213-3225
    • Ono, Y.1    Nakatani, T.2    Sakamoto, Y.3    Mizuhara, E.4    Minaki, Y.5    Kumai, M.6
  • 121
    • 0033216122 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 activates a latent neurogenic program in neural stem cells from diverse regions of the adult CNS
    • Palmer T.D., Markakis E.A., Willhoite A.R., Safar F., Gage F.H. Fibroblast growth factor-2 activates a latent neurogenic program in neural stem cells from diverse regions of the adult CNS. Journal of Neuroscience 1999, 19(19):8487-8497.
    • (1999) Journal of Neuroscience , vol.19 , Issue.19 , pp. 8487-8497
    • Palmer, T.D.1    Markakis, E.A.2    Willhoite, A.R.3    Safar, F.4    Gage, F.H.5
  • 123
    • 44649167040 scopus 로고    scopus 로고
    • Efficient generation of dopamine neurons from human embryonic stem cells
    • Park C.H., Lee S.H. Efficient generation of dopamine neurons from human embryonic stem cells. Methods in Molecular Biology 2007, 407:311-322.
    • (2007) Methods in Molecular Biology , vol.407 , pp. 311-322
    • Park, C.H.1    Lee, S.H.2
  • 124
    • 20044383922 scopus 로고    scopus 로고
    • In vitro and in vivo analyses of human embryonic stem cell-derived dopamine neurons
    • Park C.H., Minn Y.K., Lee J.Y., Choi D.H., Chang M.Y., Shim J.W., et al. In vitro and in vivo analyses of human embryonic stem cell-derived dopamine neurons. Journal of Neurochemistry 2005, 92(5):1265-1276.
    • (2005) Journal of Neurochemistry , vol.92 , Issue.5 , pp. 1265-1276
    • Park, C.H.1    Minn, Y.K.2    Lee, J.Y.3    Choi, D.H.4    Chang, M.Y.5    Shim, J.W.6
  • 125
    • 0036942868 scopus 로고    scopus 로고
    • Regional specification of neurosphere cultures derived from subregions of the embryonic telencephalon
    • Parmar M., Skogh C., Bjorklund A., Campbell K. Regional specification of neurosphere cultures derived from subregions of the embryonic telencephalon. Molecular and Cellular Neuroscience 2002, 21(4):645-656.
    • (2002) Molecular and Cellular Neuroscience , vol.21 , Issue.4 , pp. 645-656
    • Parmar, M.1    Skogh, C.2    Bjorklund, A.3    Campbell, K.4
  • 126
    • 33847314150 scopus 로고    scopus 로고
    • Tyrosine hydroxylase expression is unstable in a human immortalized mesencephalic cell line - studies in vitro and after intracerebral grafting in vivo
    • Paul G., Christophersen N.S., Raymon H., Kiaer C., Smith R., Brundin P. Tyrosine hydroxylase expression is unstable in a human immortalized mesencephalic cell line - studies in vitro and after intracerebral grafting in vivo. Molecular and Cellular Neuroscience 2007, 34(3):390-399.
    • (2007) Molecular and Cellular Neuroscience , vol.34 , Issue.3 , pp. 390-399
    • Paul, G.1    Christophersen, N.S.2    Raymon, H.3    Kiaer, C.4    Smith, R.5    Brundin, P.6
  • 128
    • 0028360518 scopus 로고
    • Bilateral motor improvement and alteration of L-dopa effect in two patients with Parkinson's disease following intrastriatal transplantation of foetal ventral mesencephalon
    • Peschanski M., Defer G., N'Guyen J.P., Ricolfi F., Monfort J.C., Remy P., et al. Bilateral motor improvement and alteration of L-dopa effect in two patients with Parkinson's disease following intrastriatal transplantation of foetal ventral mesencephalon. Brain 1994, 117(Pt 3):487-499.
    • (1994) Brain , vol.117 , Issue.PART 3 , pp. 487-499
    • Peschanski, M.1    Defer, G.2    N'Guyen, J.P.3    Ricolfi, F.4    Monfort, J.C.5    Remy, P.6
  • 129
    • 0034536630 scopus 로고    scopus 로고
    • Grafting of nigral tissue hibernated with tirilazad mesylate and glial cell line-derived neurotrophic factor
    • Petersen A., Hansson O., Emgard M., Brundin P. Grafting of nigral tissue hibernated with tirilazad mesylate and glial cell line-derived neurotrophic factor. Cell Transplantation 2000, 9(5):577-584.
    • (2000) Cell Transplantation , vol.9 , Issue.5 , pp. 577-584
    • Petersen, A.1    Hansson, O.2    Emgard, M.3    Brundin, P.4
  • 130
    • 0033491121 scopus 로고    scopus 로고
    • Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient
    • Piccini P., Brooks D.J., Bjorklund A., Gunn R.N., Grasby P.M., Rimoldi O., et al. Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient. Nature Neuroscience 1999, 2(12):1137-1140.
    • (1999) Nature Neuroscience , vol.2 , Issue.12 , pp. 1137-1140
    • Piccini, P.1    Brooks, D.J.2    Bjorklund, A.3    Gunn, R.N.4    Grasby, P.M.5    Rimoldi, O.6
  • 131
    • 0033767269 scopus 로고    scopus 로고
    • Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts
    • Piccini P., Lindvall O., Bjorklund A., Brundin P., Hagell P., Ceravolo R., et al. Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts. Annals of Neurology 2000, 48(5):689-695.
    • (2000) Annals of Neurology , vol.48 , Issue.5 , pp. 689-695
    • Piccini, P.1    Lindvall, O.2    Bjorklund, A.3    Brundin, P.4    Hagell, P.5    Ceravolo, R.6
  • 132
    • 28544441892 scopus 로고    scopus 로고
    • Factors affecting the clinical outcome after neural transplantation in Parkinson's disease
    • Piccini P., Pavese N., Hagell P., Reimer J., Bjorklund A., Oertel W.H., et al. Factors affecting the clinical outcome after neural transplantation in Parkinson's disease. Brain 2005, 128(Pt 12):2977-2986.
    • (2005) Brain , vol.128 , Issue.PART 12 , pp. 2977-2986
    • Piccini, P.1    Pavese, N.2    Hagell, P.3    Reimer, J.4    Bjorklund, A.5    Oertel, W.H.6
  • 133
    • 65249085061 scopus 로고    scopus 로고
    • BAC transgenesis in human embryonic stem cells as a novel tool to define the human neural lineage
    • Placantonakis D.G., Tomishima M.J., Lafaille F., Desbordes S.C., Jia F., Socci N.D., et al. BAC transgenesis in human embryonic stem cells as a novel tool to define the human neural lineage. Stem Cells 2009, 27(3):521-532.
    • (2009) Stem Cells , vol.27 , Issue.3 , pp. 521-532
    • Placantonakis, D.G.1    Tomishima, M.J.2    Lafaille, F.3    Desbordes, S.C.4    Jia, F.5    Socci, N.D.6
  • 134
    • 73349120240 scopus 로고    scopus 로고
    • CD15, CD24, and CD29 define a surface biomarker code for neural lineage differentiation of stem cells
    • Pruszak J., Ludwig W., Blak A., Alavian K., Isacson O. CD15, CD24, and CD29 define a surface biomarker code for neural lineage differentiation of stem cells. Stem Cells 2009, 27(12):2928-2940.
    • (2009) Stem Cells , vol.27 , Issue.12 , pp. 2928-2940
    • Pruszak, J.1    Ludwig, W.2    Blak, A.3    Alavian, K.4    Isacson, O.5
  • 137
    • 0026526516 scopus 로고
    • A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes
    • Reynolds B.A., Tetzlaff W., Weiss S. A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes. Journal of Neuroscience 1992, 12(11):4565-4574.
    • (1992) Journal of Neuroscience , vol.12 , Issue.11 , pp. 4565-4574
    • Reynolds, B.A.1    Tetzlaff, W.2    Weiss, S.3
  • 138
    • 0026535505 scopus 로고
    • Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
    • Reynolds B.A., Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 1992, 255(5052):1707-1710.
    • (1992) Science , vol.255 , Issue.5052 , pp. 1707-1710
    • Reynolds, B.A.1    Weiss, S.2
  • 139
    • 0033930711 scopus 로고    scopus 로고
    • The morphological development of neurons derived from EGF- and FGF-2-driven human CNS precursors depends on their site of integration in the neonatal rat brain
    • Rosser A.E., Tyers P., Dunnett S.B. The morphological development of neurons derived from EGF- and FGF-2-driven human CNS precursors depends on their site of integration in the neonatal rat brain. European Journal of Neuroscience 2000, 12(7):2405-2413.
    • (2000) European Journal of Neuroscience , vol.12 , Issue.7 , pp. 2405-2413
    • Rosser, A.E.1    Tyers, P.2    Dunnett, S.B.3
  • 140
    • 43649094851 scopus 로고    scopus 로고
    • Effects on differentiation of embryonic ventral midbrain progenitors by Lmx1a, Msx1, Ngn2, and Pitx3
    • Roybon L., Hjalt T., Christophersen N.S., Li J.Y., Brundin P. Effects on differentiation of embryonic ventral midbrain progenitors by Lmx1a, Msx1, Ngn2, and Pitx3. Journal of Neuroscience 2008, 28(14):3644-3656.
    • (2008) Journal of Neuroscience , vol.28 , Issue.14 , pp. 3644-3656
    • Roybon, L.1    Hjalt, T.2    Christophersen, N.S.3    Li, J.Y.4    Brundin, P.5
  • 142
    • 0025846973 scopus 로고
    • Effects of cool storage on survival and function of intrastriatal ventral mesencephalic grafts
    • Sauer H., Brundin P. Effects of cool storage on survival and function of intrastriatal ventral mesencephalic grafts. Restorative Neurology and Neuroscience 1991, 2:123-135.
    • (1991) Restorative Neurology and Neuroscience , vol.2 , pp. 123-135
    • Sauer, H.1    Brundin, P.2
  • 143
    • 2442586597 scopus 로고    scopus 로고
    • The cellular repair of the brain in Parkinson's disease-past, present and future
    • Sayles M., Jain M., Barker R.A. The cellular repair of the brain in Parkinson's disease-past, present and future. Transplant Immunology 2004, 12(3-4):321-342.
    • (2004) Transplant Immunology , vol.12 , Issue.3-4 , pp. 321-342
    • Sayles, M.1    Jain, M.2    Barker, R.A.3
  • 144
    • 71249118396 scopus 로고    scopus 로고
    • Mifepristone: Ten years later
    • Schaff E.A. Mifepristone: Ten years later. Contraception 2010, 81(1):1-7.
    • (2010) Contraception , vol.81 , Issue.1 , pp. 1-7
    • Schaff, E.A.1
  • 145
    • 53749091110 scopus 로고    scopus 로고
    • The synaptic impact of the host immune response in a parkinsonian allograft rat model: Influence on graft-derived aberrant behaviors
    • Soderstrom K.E., Meredith G., Freeman T.B., McGuire S.O., Collier T.J., Sortwell C.E., et al. The synaptic impact of the host immune response in a parkinsonian allograft rat model: Influence on graft-derived aberrant behaviors. Neurobiology of Disease 2008, 32(2):229-242.
    • (2008) Neurobiology of Disease , vol.32 , Issue.2 , pp. 229-242
    • Soderstrom, K.E.1    Meredith, G.2    Freeman, T.B.3    McGuire, S.O.4    Collier, T.J.5    Sortwell, C.E.6
  • 146
    • 61349100729 scopus 로고    scopus 로고
    • Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors
    • Soldner F., Hockemeyer D., Beard C., Gao Q., Bell G.W., Cook E.G., et al. Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell 2009, 136(5):964-977.
    • (2009) Cell , vol.136 , Issue.5 , pp. 964-977
    • Soldner, F.1    Hockemeyer, D.2    Beard, C.3    Gao, Q.4    Bell, G.W.5    Cook, E.G.6
  • 147
    • 4043078792 scopus 로고    scopus 로고
    • Detection of presymptomatic Parkinson's disease: Combining smell tests, transcranial sonography, and SPECT
    • Sommer U., Hummel T., Cormann K., Mueller A., Frasnelli J., Kropp J., et al. Detection of presymptomatic Parkinson's disease: Combining smell tests, transcranial sonography, and SPECT. Movement Disorder 2004, 19(10):1196-1202.
    • (2004) Movement Disorder , vol.19 , Issue.10 , pp. 1196-1202
    • Sommer, U.1    Hummel, T.2    Cormann, K.3    Mueller, A.4    Frasnelli, J.5    Kropp, J.6
  • 148
    • 0026447667 scopus 로고
    • Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients with Parkinson's disease
    • Spencer D.D., Robbins R.J., Naftolin F., Marek K.L., Vollmer T., Leranth C., et al. Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients with Parkinson's disease. New England Journal of Medicine 1992, 327(22):1541-1548.
    • (1992) New England Journal of Medicine , vol.327 , Issue.22 , pp. 1541-1548
    • Spencer, D.D.1    Robbins, R.J.2    Naftolin, F.3    Marek, K.L.4    Vollmer, T.5    Leranth, C.6
  • 149
    • 55849115999 scopus 로고    scopus 로고
    • Induced pluripotent stem cells generated without viral integration
    • Stadtfeld M., Nagaya M., Utikal J., Weir G., Hochedlinger K. Induced pluripotent stem cells generated without viral integration. Science 2008, 322(5903):945-949.
    • (2008) Science , vol.322 , Issue.5903 , pp. 945-949
    • Stadtfeld, M.1    Nagaya, M.2    Utikal, J.3    Weir, G.4    Hochedlinger, K.5
  • 150
    • 67650925055 scopus 로고    scopus 로고
    • Effect of levodopa priming on dopamine neuron transplant efficacy and induction of abnormal involuntary movements in parkinsonian rats
    • Steece-Collier K., Soderstrom K.E., Collier T.J., Sortwell C.E., Maries-Lad E. Effect of levodopa priming on dopamine neuron transplant efficacy and induction of abnormal involuntary movements in parkinsonian rats. Journal of Comparative Neurology 2009, 515(1):15-30.
    • (2009) Journal of Comparative Neurology , vol.515 , Issue.1 , pp. 15-30
    • Steece-Collier, K.1    Soderstrom, K.E.2    Collier, T.J.3    Sortwell, C.E.4    Maries-Lad, E.5
  • 151
    • 0034307725 scopus 로고    scopus 로고
    • Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen
    • Studer L., Csete M., Lee S.H., Kabbani N., Walikonis J., Wold B., et al. Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen. Journal of Neuroscience 2000, 20(19):7377-7383.
    • (2000) Journal of Neuroscience , vol.20 , Issue.19 , pp. 7377-7383
    • Studer, L.1    Csete, M.2    Lee, S.H.3    Kabbani, N.4    Walikonis, J.5    Wold, B.6
  • 152
    • 44649197736 scopus 로고    scopus 로고
    • Long-term tripotent differentiation capacity of human neural stem (NS) cells in adherent culture
    • Sun Y., Pollard S., Conti L., Toselli M., Biella G., Parkin G., et al. Long-term tripotent differentiation capacity of human neural stem (NS) cells in adherent culture. Molecular and Cellular Neuroscience 2008, 38(2):245-258.
    • (2008) Molecular and Cellular Neuroscience , vol.38 , Issue.2 , pp. 245-258
    • Sun, Y.1    Pollard, S.2    Conti, L.3    Toselli, M.4    Biella, G.5    Parkin, G.6
  • 154
    • 67650562117 scopus 로고    scopus 로고
    • Xeno-free defined conditions for culture of human embryonic stem cells, neural stem cells and dopaminergic neurons derived from them
    • Swistowski A., Peng J., Han Y., Swistowska A.M., Rao M.S., Zeng X. Xeno-free defined conditions for culture of human embryonic stem cells, neural stem cells and dopaminergic neurons derived from them. PLoS One 2009, 4(7):e6233.
    • (2009) PLoS One , vol.4 , Issue.7
    • Swistowski, A.1    Peng, J.2    Han, Y.3    Swistowska, A.M.4    Rao, M.S.5    Zeng, X.6
  • 155
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131(5):861-872.
    • (2007) Cell , vol.131 , Issue.5 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6
  • 156
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126(4):663-676.
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 157
    • 34447528757 scopus 로고    scopus 로고
    • New cell lines from mouse epiblast share defining features with human embryonic stem cells
    • Tesar P.J., Chenoweth J.G., Brook F.A., Davies T.J., Evans E.P., Mack D.L., et al. New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature 2007, 448(7150):196-199.
    • (2007) Nature , vol.448 , Issue.7150 , pp. 196-199
    • Tesar, P.J.1    Chenoweth, J.G.2    Brook, F.A.3    Davies, T.J.4    Evans, E.P.5    Mack, D.L.6
  • 160
    • 77649162059 scopus 로고    scopus 로고
    • Direct conversion of fibroblasts to functional neurons by defined factors
    • Vierbuchen T., Ostermeier A., Pang Z.P., Kokubu Y., Sudhof T.C., Wernig M. Direct conversion of fibroblasts to functional neurons by defined factors. Nature 2010, 463(7284):1035-1041.
    • (2010) Nature , vol.463 , Issue.7284 , pp. 1035-1041
    • Vierbuchen, T.1    Ostermeier, A.2    Pang, Z.P.3    Kokubu, Y.4    Sudhof, T.C.5    Wernig, M.6
  • 161
    • 0030834093 scopus 로고    scopus 로고
    • Short- and long-term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease
    • Wenning G.K., Odin P., Morrish P., Rehncrona S., Widner H., Brundin P., et al. Short- and long-term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease. Annals of Neurology 1997, 42(1):95-107.
    • (1997) Annals of Neurology , vol.42 , Issue.1 , pp. 95-107
    • Wenning, G.K.1    Odin, P.2    Morrish, P.3    Rehncrona, S.4    Widner, H.5    Brundin, P.6
  • 163
    • 0028314615 scopus 로고
    • NIH neural transplantation funding
    • Widner H. NIH neural transplantation funding. Science 1994, 263(5148):737.
    • (1994) Science , vol.263 , Issue.5148 , pp. 737
    • Widner, H.1
  • 164
    • 0023737839 scopus 로고
    • Immunological aspects of grafting in the mammalian central nervous system. A review and speculative synthesis
    • Widner H., Brundin P. Immunological aspects of grafting in the mammalian central nervous system. A review and speculative synthesis. Brain Research 1988, 472(3):287-324.
    • (1988) Brain Research , vol.472 , Issue.3 , pp. 287-324
    • Widner, H.1    Brundin, P.2
  • 165
    • 0026458624 scopus 로고
    • Bilateral fetal mesencephalic grafting in two patients with parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
    • Widner H., Tetrud J., Rehncrona S., Snow B., Brundin P., Gustavii B., et al. Bilateral fetal mesencephalic grafting in two patients with parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). New England Journal of Medicine 1992, 327(22):1556-1563.
    • (1992) New England Journal of Medicine , vol.327 , Issue.22 , pp. 1556-1563
    • Widner, H.1    Tetrud, J.2    Rehncrona, S.3    Snow, B.4    Brundin, P.5    Gustavii, B.6
  • 166
    • 70350641659 scopus 로고    scopus 로고
    • The distinct cognitive syndromes of Parkinson's disease: 5 year follow-up of the CamPaIGN cohort
    • Williams-Gray C.H., Evans J.R., Goris A., Foltynie T., Ban M., Robbins T.W., et al. The distinct cognitive syndromes of Parkinson's disease: 5 year follow-up of the CamPaIGN cohort. Brain 2009, 132(Pt 11):2958-2969.
    • (2009) Brain , vol.132 , Issue.PART 11 , pp. 2958-2969
    • Williams-Gray, C.H.1    Evans, J.R.2    Goris, A.3    Foltynie, T.4    Ban, M.5    Robbins, T.W.6
  • 167
    • 64749083939 scopus 로고    scopus 로고
    • PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
    • Woltjen K., Michael I.P., Mohseni P., Desai R., Mileikovsky M., Hamalainen R., et al. piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature 2009, 458(7239):766-770.
    • (2009) Nature , vol.458 , Issue.7239 , pp. 766-770
    • Woltjen, K.1    Michael, I.P.2    Mohseni, P.3    Desai, R.4    Mileikovsky, M.5    Hamalainen, R.6
  • 168
    • 0035172717 scopus 로고    scopus 로고
    • Ascorbic acid increases the yield of dopaminergic neurons derived from basic fibroblast growth factor expanded mesencephalic precursors
    • Yan J., Studer L., McKay R.D. Ascorbic acid increases the yield of dopaminergic neurons derived from basic fibroblast growth factor expanded mesencephalic precursors. Journal of Neurochemistry 2001, 76(1):307-311.
    • (2001) Journal of Neurochemistry , vol.76 , Issue.1 , pp. 307-311
    • Yan, J.1    Studer, L.2    McKay, R.D.3
  • 170
    • 8644259350 scopus 로고    scopus 로고
    • Dopaminergic differentiation of human embryonic stem cells
    • Zeng X., Cai J., Chen J., Luo Y., You Z.B., Fotter E., et al. Dopaminergic differentiation of human embryonic stem cells. Stem Cells 2004, 22(6):925-940.
    • (2004) Stem Cells , vol.22 , Issue.6 , pp. 925-940
    • Zeng, X.1    Cai, J.2    Chen, J.3    Luo, Y.4    You, Z.B.5    Fotter, E.6
  • 171
    • 53349178722 scopus 로고    scopus 로고
    • In vivo reprogramming of adult pancreatic exocrine cells to beta-cells
    • Zhou Q., Brown J., Kanarek A., Rajagopal J., Melton D.A. In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature 2008, 455(7213):627-632.
    • (2008) Nature , vol.455 , Issue.7213 , pp. 627-632
    • Zhou, Q.1    Brown, J.2    Kanarek, A.3    Rajagopal, J.4    Melton, D.A.5
  • 172
    • 33750290419 scopus 로고    scopus 로고
    • Triggering endogenous neuroprotective mechanisms in Parkinson's disease: Studies with a cellular model
    • Zigmond M.J. Triggering endogenous neuroprotective mechanisms in Parkinson's disease: Studies with a cellular model. Journal of Neural Transmission 2006, 70(Suppl):439-442.
    • (2006) Journal of Neural Transmission , vol.70 , Issue.SUPPL. , pp. 439-442
    • Zigmond, M.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.