메뉴 건너뛰기




Volumn 9, Issue 9, 2008, Pages 725-729

The promise of human induced pluripotent stem cells for research and therapy

Author keywords

[No Author keywords available]

Indexed keywords

CANCER RESEARCH; CELL STIMULATION; CELL THERAPY; EMBRYONIC STEM CELL; EPIGENETICS; GENETIC TRANSDUCTION; INDUCED PLURIPOTENT STEM CELL; MEDICAL RESEARCH; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; REVIEW;

EID: 50149108172     PISSN: 14710072     EISSN: 14710080     Source Type: Journal    
DOI: 10.1038/nrm2466     Document Type: Review
Times cited : (377)

References (43)
  • 1
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi, K. & Yamanaka, S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676 (2006).
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 2
    • 41949134533 scopus 로고    scopus 로고
    • Generation of pluripotent stem cells from adult mouse liver and stomach cells
    • 14 Feb, doi:10.1126/science. 1154884
    • Aoi, T. et al. Generation of pluripotent stem cells from adult mouse liver and stomach cells. Science 14 Feb 2008 (doi:10.1126/science. 1154884)
    • (2008) Science
    • Aoi, T.1
  • 3
    • 34249880066 scopus 로고    scopus 로고
    • Generation of germline-competent induced pluripotent stem cells
    • Okita, K., Ichisaka, T. & Yamanaka, S. Generation of germline-competent induced pluripotent stem cells. Nature 448, 313-317 (2007).
    • (2007) Nature , vol.448 , pp. 313-317
    • Okita, K.1    Ichisaka, T.2    Yamanaka, S.3
  • 4
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi, K. et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872 (2007).
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1
  • 5
    • 36749043230 scopus 로고    scopus 로고
    • Induced pluripotent stem cells from adult human somatic cells
    • Yu, J. et al. Induced pluripotent stem cells from adult human somatic cells. Science 318, 1917-1920 (2007).
    • (2007) Science , vol.318 , pp. 1917-1920
    • Yu, J.1
  • 6
    • 38049187707 scopus 로고    scopus 로고
    • Reprogramming of human somatic cells to pluripotency with defined factors
    • Park, I.-H. et al. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 451, 141-147 (2008).
    • (2008) Nature , vol.451 , pp. 141-147
    • Park, I.-H.1
  • 7
    • 41349090105 scopus 로고    scopus 로고
    • Generation of human induced pluripotent stem cells from dermal fibroblasts
    • Lowry, W. E. et al. Generation of human induced pluripotent stem cells from dermal fibroblasts. Proc. Natl Acad. Sci. USA 105, 2883-2888 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 2883-2888
    • Lowry, W.E.1
  • 8
    • 34548445454 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells in the absence of drug selection
    • Blelloch, R. et al. Generation of induced pluripotent stem cells in the absence of drug selection. Cell Stem Cell 1, 245-247 (2007).
    • (2007) Cell Stem Cell , vol.1 , pp. 245-247
    • Blelloch, R.1
  • 9
    • 39149086020 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from fibroblast cultures
    • Takahashi, K., Okita, K., Nakagawa, M. & Yamanaka, S. Induction of pluripotent stem cells from fibroblast cultures. Nature Protoc. 2, 3081-3089 (2007).
    • (2007) Nature Protoc , vol.2 , pp. 3081-3089
    • Takahashi, K.1    Okita, K.2    Nakagawa, M.3    Yamanaka, S.4
  • 10
    • 34249863603 scopus 로고    scopus 로고
    • Strategies and new developments in the generation of patient-specific pluripotent stem cells
    • Yamanaka, S. Strategies and new developments in the generation of patient-specific pluripotent stem cells. Cell Stem Cell 1, 39-49 (2007).
    • (2007) Cell Stem Cell , vol.1 , pp. 39-49
    • Yamanaka, S.1
  • 11
    • 37549052191 scopus 로고
    • Development: Is therapeutic cloning dead?
    • 2007
    • Cibelli, J. Development: is therapeutic cloning dead? Science 318, 1879-1880 (2007).
    • (1879) Science , vol.318
    • Cibelli, J.1
  • 12
    • 39149130361 scopus 로고    scopus 로고
    • Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming
    • Jaenisch, R. & Young, R. Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell 132, 567-582 (2008).
    • (2008) Cell , vol.132 , pp. 567-582
    • Jaenisch, R.1    Young, R.2
  • 13
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson, J. A. et al. Embryonic stem cell lines derived from human blastocysts. Science 282, 1145-1147 (1998).
    • (1998) Science , vol.282 , pp. 1145-1147
    • Thomson, J.A.1
  • 14
    • 23944457397 scopus 로고    scopus 로고
    • Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells
    • Cowan, C. A., Atienza, J., Melton, D. A. & Eggan, K. Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells. Science 309, 1369-1373 (2005).
    • (2005) Science , vol.309 , pp. 1369-1373
    • Cowan, C.A.1    Atienza, J.2    Melton, D.A.3    Eggan, K.4
  • 15
    • 34848900412 scopus 로고    scopus 로고
    • Reprogramming somatic gene activity by fusion with pluripotent cells
    • Do, J. T., Han, D. W. & Scholer, H. R. Reprogramming somatic gene activity by fusion with pluripotent cells. Stem Cell Rev. 2, 257-264 (2006).
    • (2006) Stem Cell Rev , vol.2 , pp. 257-264
    • Do, J.T.1    Han, D.W.2    Scholer, H.R.3
  • 16
    • 33745632618 scopus 로고    scopus 로고
    • Nuclear reprogramming and pluripotency
    • Hochedlinger, K. & Jaenisch, R. Nuclear reprogramming and pluripotency. Nature 441, 1061-1067 (2006).
    • (2006) Nature , vol.441 , pp. 1061-1067
    • Hochedlinger, K.1    Jaenisch, R.2
  • 17
    • 39349106325 scopus 로고    scopus 로고
    • Differentiation of embryonic stem cells to clinically relevant populations: Lessons from embryonic development
    • Murry, C. E. & Keller, G. Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. Cell 132, 661-680 (2008).
    • (2008) Cell , vol.132 , pp. 661-680
    • Murry, C.E.1    Keller, G.2
  • 18
    • 27644582657 scopus 로고    scopus 로고
    • Therapeutic potential of embryonic stem cells
    • Lerou, P. H. & Daley, G. Q. Therapeutic potential of embryonic stem cells. Blood Rev. 19, 321-331 (2005).
    • (2005) Blood Rev , vol.19 , pp. 321-331
    • Lerou, P.H.1    Daley, G.Q.2
  • 19
    • 34249908901 scopus 로고    scopus 로고
    • In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
    • Wernig, M. et al. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 448, 318-324 (2007).
    • (2007) Nature , vol.448 , pp. 318-324
    • Wernig, M.1
  • 20
    • 34249909232 scopus 로고    scopus 로고
    • Directly reprogrammed fibroblasts show epigenetic remodeling and widespread tissue contribution
    • Maherali, N. et al. Directly reprogrammed fibroblasts show epigenetic remodeling and widespread tissue contribution. Cell Stem Cell 1, 55-70 (2007).
    • (2007) Cell Stem Cell , vol.1 , pp. 55-70
    • Maherali, N.1
  • 21
    • 37549030199 scopus 로고    scopus 로고
    • Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin
    • Hanna, J. et al. Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science 318, 1920-1923 (2007).
    • (2007) Science , vol.318 , pp. 1920-1923
    • Hanna, J.1
  • 22
    • 34447295350 scopus 로고    scopus 로고
    • Characterization of human embryonic stem cell lines by the International Stem Cell Initiative
    • The International Stem Cell Initiative
    • The International Stem Cell Initiative. Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nature Biotech. 25, 803-816 (2007).
    • (2007) Nature Biotech , vol.25 , pp. 803-816
  • 23
    • 40449109390 scopus 로고    scopus 로고
    • iPS cells and the politics of promise
    • Gottweis, H. & Minger, S. iPS cells and the politics of promise. Nature Biotech. 26, 271-272 (2008).
    • (2008) Nature Biotech , vol.26 , pp. 271-272
    • Gottweis, H.1    Minger, S.2
  • 24
    • 41349116799 scopus 로고    scopus 로고
    • Five things to know before jumping on the iPS bandwagon
    • Cyranoski, D. Five things to know before jumping on the iPS bandwagon. Nature 452, 406-408 (2008).
    • (2008) Nature , vol.452 , pp. 406-408
    • Cyranoski, D.1
  • 25
    • 38049028459 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
    • Nakagawa, M. et al. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nature Biotech. 26, 101-106 (2008).
    • (2008) Nature Biotech , vol.26 , pp. 101-106
    • Nakagawa, M.1
  • 26
    • 40449141341 scopus 로고    scopus 로고
    • Marked differences in differentiation propensity among human embryonic stem cell lines
    • Osafune, K. et al. Marked differences in differentiation propensity among human embryonic stem cell lines. Nature Biotech. 26, 313-315 (2008).
    • (2008) Nature Biotech , vol.26 , pp. 313-315
    • Osafune, K.1
  • 27
    • 0003716535 scopus 로고    scopus 로고
    • Food and Drug Administration [online, 1998
    • US Department of Health and Human Services. Guidance for human somatic cell therapy and gene therapy. Food and Drug Administration [online], http://www.fda.gov/Cber/gdlns/somgene.pdf (1998).
    • Guidance for human somatic cell therapy and gene therapy
  • 28
    • 39749105397 scopus 로고    scopus 로고
    • Stem cell therapy for cardiac disease
    • Segers, V. F. M. & Lee, R. T. Stem cell therapy for cardiac disease. Nature 451, 937-942 (2008).
    • (2008) Nature , vol.451 , pp. 937-942
    • Segers, V.F.M.1    Lee, R.T.2
  • 29
    • 35348850693 scopus 로고    scopus 로고
    • Concise review: Roles of polycomb group proteins in development and disease: a stem cell perspective
    • Rajasekhar, V. K. & Begemann, M. Concise review: roles of polycomb group proteins in development and disease: a stem cell perspective. Stem Cells 25, 2498-2510 (2007).
    • (2007) Stem Cells , vol.25 , pp. 2498-2510
    • Rajasekhar, V.K.1    Begemann, M.2
  • 30
    • 33947301272 scopus 로고    scopus 로고
    • Epigenetic signatures of stem-cell identity
    • Spivakov, M. & Fisher, A. G. Epigenetic signatures of stem-cell identity. Nature Rev. Genetics 8, 263-271 (2007).
    • (2007) Nature Rev. Genetics , vol.8 , pp. 263-271
    • Spivakov, M.1    Fisher, A.G.2
  • 31
    • 38849209222 scopus 로고    scopus 로고
    • A seismic shift for stem cell research
    • Holden, C. & Vogel, G. A seismic shift for stem cell research. Science 319, 560-563 (2008).
    • (2008) Science , vol.319 , pp. 560-563
    • Holden, C.1    Vogel, G.2
  • 32
    • 33846225133 scopus 로고    scopus 로고
    • Huntington's disease
    • Walker, F. O. Huntington's disease. Lancet 369, 218-228 (2007).
    • (2007) Lancet , vol.369 , pp. 218-228
    • Walker, F.O.1
  • 33
    • 41949098160 scopus 로고    scopus 로고
    • Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency
    • Hanna, J. et al. Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency. Cell 133, 250-264 (2008).
    • (2008) Cell , vol.133 , pp. 250-264
    • Hanna, J.1
  • 34
    • 84872226181 scopus 로고    scopus 로고
    • National Cancer Institute [online, 2008
    • National Cancer Institute. Cancer biomedical informatics grid. National Cancer Institute [online], https://cabig.nci.nih.gov/ (2008).
    • Cancer biomedical informatics grid
  • 35
    • 4644344326 scopus 로고    scopus 로고
    • Nuclear cloning of embryonal carcinoma cells
    • Blelloch, R. H. et al. Nuclear cloning of embryonal carcinoma cells. Proc. Natl Acad. Sci. USA 101, 13985-13990 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 13985-13990
    • Blelloch, R.H.1
  • 36
    • 33947315736 scopus 로고    scopus 로고
    • Cancer epigenomics: DNA methylomes and histone-modification maps
    • Esteller, M. Cancer epigenomics: DNA methylomes and histone-modification maps. Nature Rev. Genetics 8, 286-298 (2007).
    • (2007) Nature Rev. Genetics , vol.8 , pp. 286-298
    • Esteller, M.1
  • 37
    • 3543073392 scopus 로고    scopus 로고
    • Reprogramming of a melanoma genome by nuclear transplantation
    • Hochedlinger, K. et al. Reprogramming of a melanoma genome by nuclear transplantation. Genes Dev. 18, 1875-1885 (2004).
    • (2004) Genes Dev , vol.18 , pp. 1875-1885
    • Hochedlinger, K.1
  • 38
    • 33750733285 scopus 로고    scopus 로고
    • Genome-wide analysis of histone modifications by ChIP-on-chip
    • Huebert, D. J. Kamal, M., O'Donovan, A. & Bernstein, B. E. Genome-wide analysis of histone modifications by ChIP-on-chip. Methods 40, 365-369 (2006).
    • (2006) Methods , vol.40 , pp. 365-369
    • Huebert, D.J.1    Kamal, M.2    O'Donovan, A.3    Bernstein, B.E.4
  • 39
    • 34547633677 scopus 로고    scopus 로고
    • Genome-wide profiling of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing
    • Robertson, G. et al. Genome-wide profiling of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing. Nature Methods 4, 651-657 (2007).
    • (2007) Nature Methods , vol.4 , pp. 651-657
    • Robertson, G.1
  • 40
    • 33846630040 scopus 로고    scopus 로고
    • Humanized mice in translational biomedical research
    • Shultz, L. D., Ishikawa, F. & Greiner, D. L. Humanized mice in translational biomedical research. Nature Rev. Immunol. 7, 118-130 (2007).
    • (2007) Nature Rev. Immunol , vol.7 , pp. 118-130
    • Shultz, L.D.1    Ishikawa, F.2    Greiner, D.L.3
  • 41
    • 50149098605 scopus 로고    scopus 로고
    • Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
    • 31 July, doi:10.1126/science.1158799
    • Dimos, J. T. et al. Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science 31 July 2008 (doi:10.1126/science.1158799)
    • (2008) Science
    • Dimos, J.T.1
  • 42
    • 85100509474 scopus 로고    scopus 로고
    • Disease-specific induced pluripotent stem cells
    • in the press
    • Park, I.-H. et al. Disease-specific induced pluripotent stem cells. Cell (in the press).
    • Cell
    • Park, I.-H.1
  • 43
    • 48349095740 scopus 로고    scopus 로고
    • Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors
    • Kim, J. B. et al. Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors. Nature 454, 646-650 (2008).
    • (2008) Nature , vol.454 , pp. 646-650
    • Kim, J.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.