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Volumn 313, Issue 6, 2007, Pages 1172-1180

Ngn2 and Nurr1 act in synergy to induce midbrain dopaminergic neurons from expanded neural stem and progenitor cells

Author keywords

Cell replacement; Dopamine; In vitro differentiation; Midbrain; Neurosphere; Ngn2; Nurr1; Retrovirus; TH

Indexed keywords

NGN2 PROTEIN; NUCLEAR RECEPTOR RELATED FACTOR 1; PROTEIN; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG;

EID: 33947206784     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2006.12.014     Document Type: Article
Times cited : (64)

References (37)
  • 1
    • 0029114373 scopus 로고
    • Time of neuron origin and gradients of neurogenesis in midbrain dopaminergic neurons in the mouse
    • Bayer S.A., Wills K.V., Triarhou L.C., and Ghetti B. Time of neuron origin and gradients of neurogenesis in midbrain dopaminergic neurons in the mouse. Exp. Brain Res. 105 (1995) 191-199
    • (1995) Exp. Brain Res. , vol.105 , pp. 191-199
    • Bayer, S.A.1    Wills, K.V.2    Triarhou, L.C.3    Ghetti, B.4
  • 2
    • 33747670219 scopus 로고    scopus 로고
    • Genetic networks controlling the development of midbrain dopaminergic neurons
    • Prakash N., and Wurst W. Genetic networks controlling the development of midbrain dopaminergic neurons. J. Physiol. (2006)
    • (2006) J. Physiol.
    • Prakash, N.1    Wurst, W.2
  • 3
    • 30744461567 scopus 로고    scopus 로고
    • Development of dopaminergic neurons in the mammalian brain
    • Prakash N., and Wurst W. Development of dopaminergic neurons in the mammalian brain. Cell. Mol. Life Sci. 63 (2006) 187-206
    • (2006) Cell. Mol. Life Sci. , vol.63 , pp. 187-206
    • Prakash, N.1    Wurst, W.2
  • 5
    • 20444376889 scopus 로고    scopus 로고
    • Pitx3 regulates tyrosine hydroxylase expression in the substantia nigra and identifies a subgroup of mesencephalic dopaminergic progenitor neurons during mouse development
    • Maxwell S.L., Ho H.Y., Kuehner E., Zhao S., and Li M. Pitx3 regulates tyrosine hydroxylase expression in the substantia nigra and identifies a subgroup of mesencephalic dopaminergic progenitor neurons during mouse development. Dev. Biol. 282 (2005) 467-479
    • (2005) Dev. Biol. , vol.282 , pp. 467-479
    • Maxwell, S.L.1    Ho, H.Y.2    Kuehner, E.3    Zhao, S.4    Li, M.5
  • 8
    • 33744979316 scopus 로고    scopus 로고
    • Stromal cell-derived inducing activity, Nurr1, and signaling molecules synergistically induce dopaminergic neurons from mouse embryonic stem cells
    • Kim D.W., Chung S., Hwang M., Ferree A., Tsai H.C., Park J.J., Chung S., Nam T.S., Kang U.J., Isacson O., and Kim K.S. Stromal cell-derived inducing activity, Nurr1, and signaling molecules synergistically induce dopaminergic neurons from mouse embryonic stem cells. Stem Cells 24 (2006) 557-567
    • (2006) Stem Cells , vol.24 , pp. 557-567
    • Kim, D.W.1    Chung, S.2    Hwang, M.3    Ferree, A.4    Tsai, H.C.5    Park, J.J.6    Chung, S.7    Nam, T.S.8    Kang, U.J.9    Isacson, O.10    Kim, K.S.11
  • 10
    • 1642264043 scopus 로고    scopus 로고
    • Temporally induced Nurr1 can induce a non-neuronal dopaminergic cell type in embryonic stem cell differentiation
    • Sonntag K.C., Simantov R., Kim K.S., and Isacson O. Temporally induced Nurr1 can induce a non-neuronal dopaminergic cell type in embryonic stem cell differentiation. Eur. J. Neurosci. 19 (2004) 1141-1152
    • (2004) Eur. J. Neurosci. , vol.19 , pp. 1141-1152
    • Sonntag, K.C.1    Simantov, R.2    Kim, K.S.3    Isacson, O.4
  • 11
    • 0036631456 scopus 로고    scopus 로고
    • Proneural genes and the specification of neural cell types
    • Bertrand N., Castro D.S., and Guillemot F. Proneural genes and the specification of neural cell types. Nat. Rev., Neurosci. 3 (2002) 517-530
    • (2002) Nat. Rev., Neurosci. , vol.3 , pp. 517-530
    • Bertrand, N.1    Castro, D.S.2    Guillemot, F.3
  • 12
    • 0033967842 scopus 로고    scopus 로고
    • A role for neural determination genes in specifying the dorsoventral identity of telencephalic neurons
    • Fode C., Ma Q., Casarosa S., Ang S.L., Anderson D.J., and Guillemot F. A role for neural determination genes in specifying the dorsoventral identity of telencephalic neurons. Genes Dev. 14 (2000) 67-80
    • (2000) Genes Dev. , vol.14 , pp. 67-80
    • Fode, C.1    Ma, Q.2    Casarosa, S.3    Ang, S.L.4    Anderson, D.J.5    Guillemot, F.6
  • 13
    • 33244496187 scopus 로고    scopus 로고
    • Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons
    • Kele J., Simplicio N., Ferri A.L., Mira H., Guillemot F., Arenas E., and Ang S.L. Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons. Development 133 (2006) 495-505
    • (2006) Development , vol.133 , pp. 495-505
    • Kele, J.1    Simplicio, N.2    Ferri, A.L.3    Mira, H.4    Guillemot, F.5    Arenas, E.6    Ang, S.L.7
  • 14
  • 15
    • 33244474408 scopus 로고    scopus 로고
    • Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2
    • Andersson E., Jensen J.B., Parmar M., Guillemot F., and Bjorklund A. Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2. Development 133 (2006) 507-516
    • (2006) Development , vol.133 , pp. 507-516
    • Andersson, E.1    Jensen, J.B.2    Parmar, M.3    Guillemot, F.4    Bjorklund, A.5
  • 17
    • 33747587820 scopus 로고    scopus 로고
    • Neural precursors derived from embryonic stem cells, but not those from fetal ventral mesencephalon, maintain the potential to differentiate into dopaminergic neurons after expansion in vitro
    • Chung S., Shin B.S., Hwang M., Lardaro T., Kang U.J., Isacson O., and Kim K.S. Neural precursors derived from embryonic stem cells, but not those from fetal ventral mesencephalon, maintain the potential to differentiate into dopaminergic neurons after expansion in vitro. Stem Cells 24 (2006) 1583-1593
    • (2006) Stem Cells , vol.24 , pp. 1583-1593
    • Chung, S.1    Shin, B.S.2    Hwang, M.3    Lardaro, T.4    Kang, U.J.5    Isacson, O.6    Kim, K.S.7
  • 18
    • 27744478490 scopus 로고    scopus 로고
    • Stromal cell-derived inducing activity does not promote dopaminergic differentiation, but enhances differentiation and proliferation of neural stem cell-derived astrocytes
    • Roybon L., Brundin P., and Li J.Y. Stromal cell-derived inducing activity does not promote dopaminergic differentiation, but enhances differentiation and proliferation of neural stem cell-derived astrocytes. Exp. Neurol. 196 (2005) 373-380
    • (2005) Exp. Neurol. , vol.196 , pp. 373-380
    • Roybon, L.1    Brundin, P.2    Li, J.Y.3
  • 19
    • 16444372503 scopus 로고    scopus 로고
    • Effect of cell-density on in-vitro dopaminergic differentiation of mesencephalic precursor cells
    • Ko J.Y., Lee J.Y., Park C.H., and Lee S.H. Effect of cell-density on in-vitro dopaminergic differentiation of mesencephalic precursor cells. NeuroReport 16 (2005) 499-503
    • (2005) NeuroReport , vol.16 , pp. 499-503
    • Ko, J.Y.1    Lee, J.Y.2    Park, C.H.3    Lee, S.H.4
  • 20
    • 0035172717 scopus 로고    scopus 로고
    • Ascorbic acid increases the yield of dopaminergic neurons derived from basic fibroblast growth factor expanded mesencephalic precursors
    • Yan J., Studer L., and McKay R.D. Ascorbic acid increases the yield of dopaminergic neurons derived from basic fibroblast growth factor expanded mesencephalic precursors. J. Neurochem. 76 (2001) 307-311
    • (2001) J. Neurochem. , vol.76 , pp. 307-311
    • Yan, J.1    Studer, L.2    McKay, R.D.3
  • 21
    • 0029862497 scopus 로고    scopus 로고
    • A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes
    • Ory D.S., Neugeboren B.A., and Mulligan R.C. A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 11400-11406
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 11400-11406
    • Ory, D.S.1    Neugeboren, B.A.2    Mulligan, R.C.3
  • 23
    • 0000190727 scopus 로고    scopus 로고
    • Cellular expression of the immediate early transcription factors Nurr1 and NGFI-B suggests a gene regulatory role in several brain regions including the nigrostriatal dopamine system
    • Zetterstrom R.H., Williams R., Perlmann T., and Olson L. Cellular expression of the immediate early transcription factors Nurr1 and NGFI-B suggests a gene regulatory role in several brain regions including the nigrostriatal dopamine system. Brain Res. Mol. Brain Res. 41 (1996) 111-120
    • (1996) Brain Res. Mol. Brain Res. , vol.41 , pp. 111-120
    • Zetterstrom, R.H.1    Williams, R.2    Perlmann, T.3    Olson, L.4
  • 24
    • 0242708712 scopus 로고    scopus 로고
    • Involvement of Nurr1 in specifying the neurotransmitter identity of ventral midbrain dopaminergic neurons
    • Smits S.M., Ponnio T., Conneely O.M., Burbach J.P., and Smidt M.P. Involvement of Nurr1 in specifying the neurotransmitter identity of ventral midbrain dopaminergic neurons. Eur. J. Neurosci. 18 (2003) 1731-1738
    • (2003) Eur. J. Neurosci. , vol.18 , pp. 1731-1738
    • Smits, S.M.1    Ponnio, T.2    Conneely, O.M.3    Burbach, J.P.4    Smidt, M.P.5
  • 25
    • 0031805754 scopus 로고    scopus 로고
    • Dopamine biosynthesis is selectively abolished in substantia nigra/ventral tegmental area but not in hypothalamic neurons in mice with targeted disruption of the Nurr1 gene
    • Castillo S.O., Baffi J.S., Palkovits M., Goldstein D.S., Kopin I.J., Witta J., Magnuson M.A., and Nikodem V.M. Dopamine biosynthesis is selectively abolished in substantia nigra/ventral tegmental area but not in hypothalamic neurons in mice with targeted disruption of the Nurr1 gene. Mol. Cell. Neurosci. 11 (1998) 36-46
    • (1998) Mol. Cell. Neurosci. , vol.11 , pp. 36-46
    • Castillo, S.O.1    Baffi, J.S.2    Palkovits, M.3    Goldstein, D.S.4    Kopin, I.J.5    Witta, J.6    Magnuson, M.A.7    Nikodem, V.M.8
  • 27
  • 28
    • 4243579992 scopus 로고    scopus 로고
    • Ontogeny of vesicular amine transporter expression in the rat: new perspectives on aminergic neuronal and neuroendocrine differentiation
    • Schutz B., Schafer M.K., Eiden L.E., and Weihe E. Ontogeny of vesicular amine transporter expression in the rat: new perspectives on aminergic neuronal and neuroendocrine differentiation. Adv. Pharmacol. 42 (1998) 903-908
    • (1998) Adv. Pharmacol. , vol.42 , pp. 903-908
    • Schutz, B.1    Schafer, M.K.2    Eiden, L.E.3    Weihe, E.4
  • 29
    • 0035930492 scopus 로고    scopus 로고
    • Neurons in the monoaminergic nuclei of the rat and human central nervous system express FA1/dlk
    • Jensen C.H., Meyer M., Schroder H.D., Kliem A., Zimmer J., and Teisner B. Neurons in the monoaminergic nuclei of the rat and human central nervous system express FA1/dlk. NeuroReport 12 (2001) 3959-3963
    • (2001) NeuroReport , vol.12 , pp. 3959-3963
    • Jensen, C.H.1    Meyer, M.2    Schroder, H.D.3    Kliem, A.4    Zimmer, J.5    Teisner, B.6
  • 30
    • 0035341443 scopus 로고    scopus 로고
    • Fate of midbrain dopaminergic neurons controlled by the engrailed genes
    • Simon H.H., Saueressig H., Wurst W., Goulding M.D., and O'Leary D.D. Fate of midbrain dopaminergic neurons controlled by the engrailed genes. J. Neurosci. 21 (2001) 3126-3134
    • (2001) J. Neurosci. , vol.21 , pp. 3126-3134
    • Simon, H.H.1    Saueressig, H.2    Wurst, W.3    Goulding, M.D.4    O'Leary, D.D.5
  • 31
    • 4043165474 scopus 로고    scopus 로고
    • Engrailed genes are cell-autonomously required to prevent apoptosis in mesencephalic dopaminergic neurons
    • Alberi L., Sgado P., and Simon H.H. Engrailed genes are cell-autonomously required to prevent apoptosis in mesencephalic dopaminergic neurons. Development 131 (2004) 3229-3236
    • (2004) Development , vol.131 , pp. 3229-3236
    • Alberi, L.1    Sgado, P.2    Simon, H.H.3
  • 33
    • 0242499436 scopus 로고    scopus 로고
    • Molecular mechanisms underlying midbrain dopamine neuron development and function
    • Smidt M.P., Smits S.M., and Burbach J.P. Molecular mechanisms underlying midbrain dopamine neuron development and function. Eur. J. Pharmacol. 480 (2003) 75-88
    • (2003) Eur. J. Pharmacol. , vol.480 , pp. 75-88
    • Smidt, M.P.1    Smits, S.M.2    Burbach, J.P.3
  • 35
    • 33947286717 scopus 로고    scopus 로고
    • Control of neurogenesis and tyrosine hydroxylase expression in neural progenitor cells through bHLH proteins and Nurr1
    • Kim H.J., Sugimori M., Nakafuku M., and Svendsen C.N. Control of neurogenesis and tyrosine hydroxylase expression in neural progenitor cells through bHLH proteins and Nurr1. Exp. Neurol. (2006)
    • (2006) Exp. Neurol.
    • Kim, H.J.1    Sugimori, M.2    Nakafuku, M.3    Svendsen, C.N.4
  • 37
    • 0027979793 scopus 로고
    • Target and neurotransmitter specificity of fetal central nervous system transplants: importance for functional reinnervation
    • Hudson J.L., Bickford P., Johansson M., Hoffer B.J., and Stromberg I. Target and neurotransmitter specificity of fetal central nervous system transplants: importance for functional reinnervation. J. Neurosci. 14 (1994) 283-290
    • (1994) J. Neurosci. , vol.14 , pp. 283-290
    • Hudson, J.L.1    Bickford, P.2    Johansson, M.3    Hoffer, B.J.4    Stromberg, I.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.