ERK5 is required for VEGF-mediated survival and tubular morphogenesis of primary human microvascular endothelial cells

Journal of Cell Science

Volumn 123, Issue 18, 2010, Pages 3189-3200

  Roberts, Owain Llŷr ^a   Holmes, Katherine ^b   Müller, Jürgen ^c   Cross, Darren A E ^d   Cross, Michael J ^b  

^a BANGOR UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c UNIVERSITY OF WARWICK   (United Kingdom)

^d ASTRAZENECA   (United Kingdom)

Author keywords

AKT; Angiogenesis; Endothelial; ERK5; Signal transduction; VEGF

Indexed keywords

CASPASE 3; COLLAGEN GEL; GELATIN; MITOGEN ACTIVATED PROTEIN KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE 5; PROTEIN BAD; PROTEIN BCL 2; PROTEIN KINASE B; SMALL INTERFERING RNA; VASCULOTROPIN;

ANGIOGENESIS; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE SILENCING; HUMAN; HUMAN CELL; MICROVASCULATURE; MORPHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM;

ANIMALS; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; DERMIS; ENDOTHELIAL CELLS; HUMANS; MICE; MICROVESSELS; MITOGEN-ACTIVATED PROTEIN KINASE 7; NEOVASCULARIZATION, PHYSIOLOGIC; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

MUS;

EID: 77956934798     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.072801     Document Type: Article

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