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Volumn 126, Issue 6, 1999, Pages 1149-1159

VEGF is required for growth and survival in neonatal mice

Author keywords

Angiogenesis; Apoptosis; Body growth; Conditional gene targeting; CrelloxP; Endothelium; Mouse; Vascular endothelial growth factor (VEGF); VEGF receptors

Indexed keywords

CHIMERIC PROTEIN; IMMUNOGLOBULIN G; PROTEIN INHIBITOR; VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

EID: 0032931234     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (786)

References (52)
  • 1
    • 0028803509 scopus 로고
    • Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity
    • Alon, T., Hemo, I., Itin, A., Pe'er, J., Stone, J. and Keshet, E. (1995). Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity. Nat. Med. 1, 1024-028.
    • (1995) Nat. Med. , vol.1 , pp. 1024-1028
    • Alon, T.1    Hemo, I.2    Itin, A.3    Pe'er, J.4    Stone, J.5    Keshet, E.6
  • 2
    • 0029116088 scopus 로고
    • Ovarian angiogenesis. Phenotypic characterization of endothelial cells in a physiological model of blood vessel growth and regression
    • Augustin, H. G., Braun, K., Telemenakis, I., Modlich, U. and Kuhn, W. (1995). Ovarian angiogenesis. Phenotypic characterization of endothelial cells in a physiological model of blood vessel growth and regression. Am. J. Pathol. 147, 339-351.
    • (1995) Am. J. Pathol. , vol.147 , pp. 339-351
    • Augustin, H.G.1    Braun, K.2    Telemenakis, I.3    Modlich, U.4    Kuhn, W.5
  • 3
    • 0027423419 scopus 로고
    • Role of insulin-like growth factors in embryonic and postnatal growth
    • Baker, J., Liu, J. P., Robertson, E. J. and Efstratiadis, A. (1993). Role of insulin-like growth factors in embryonic and postnatal growth. Cell 75, 73-82.
    • (1993) Cell , vol.75 , pp. 73-82
    • Baker, J.1    Liu, J.P.2    Robertson, E.J.3    Efstratiadis, A.4
  • 4
    • 0031834239 scopus 로고    scopus 로고
    • A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF
    • Benjamin, L., Hemo, I. and Keshet, E. (1998). A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development 125, 1591-1598.
    • (1998) Development , vol.125 , pp. 1591-1598
    • Benjamin, L.1    Hemo, I.2    Keshet, E.3
  • 5
    • 0030806273 scopus 로고    scopus 로고
    • Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: Induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal
    • Benjamin, L. E. and Keshet, E. (1997). Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal Proc. Natl. Acad. Sci. USA 94, 8761-8766.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 8761-8766
    • Benjamin, L.E.1    Keshet, E.2
  • 6
    • 0031898292 scopus 로고    scopus 로고
    • Neutralizing anti-vascular endothelial growth factor antibody completely inhibits angiogenesis and growth of human prostate carcinoma micro tumors in vivo
    • Borgström, P., Bourdon, M. A., Hillan, K. J., Sriramarao, P. and Ferrara, N. (1998). Neutralizing anti-vascular endothelial growth factor antibody completely inhibits angiogenesis and growth of human prostate carcinoma micro tumors in vivo. Prostate 35, 1-10.
    • (1998) Prostate , vol.35 , pp. 1-10
    • Borgström, P.1    Bourdon, M.A.2    Hillan, K.J.3    Sriramarao, P.4    Ferrara, N.5
  • 7
    • 0028670833 scopus 로고
    • Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
    • Brooks, P. C., Montgomery, A. M., Rosenfeld, M., Reisfeld, R. A., Hu, T., Klier, G. and Cheresh, D. A. (1994). Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 79, 1157-1164.
    • (1994) Cell , vol.79 , pp. 1157-1164
    • Brooks, P.C.1    Montgomery, A.M.2    Rosenfeld, M.3    Reisfeld, R.A.4    Hu, T.5    Klier, G.6    Cheresh, D.A.7
  • 9
    • 0031780324 scopus 로고    scopus 로고
    • Vascular development and disorders: Molecular analysis and pathogenic insights
    • Carmeliet, P. and Collen, D. (1998). Vascular development and disorders: Molecular analysis and pathogenic insights. Kidney Internat. 53, 1519-1549.
    • (1998) Kidney Internat. , vol.53 , pp. 1519-1549
    • Carmeliet, P.1    Collen, D.2
  • 11
    • 0027236943 scopus 로고
    • The 16-kilodalton N-terminal fragment of human prolactin is a potent inhibitor of angiogenesis
    • Clapp, C., Martial, J. A., Guzman, R. C., Rentier-Delrue, F. and Weiner, R. I. (1993). The 16-kilodalton N-terminal fragment of human prolactin is a potent inhibitor of angiogenesis. Endocrinology 133, 1292-1299.
    • (1993) Endocrinology , vol.133 , pp. 1292-1299
    • Clapp, C.1    Martial, J.A.2    Guzman, R.C.3    Rentier-Delrue, F.4    Weiner, R.I.5
  • 12
    • 0029790466 scopus 로고    scopus 로고
    • The second immunoglobulin-like domain of the VEGF tyrosine kinase receptor Flt-1 determines ligand binding and may initiate a signal transduction cascade
    • Davis-Smyth, T., Chen, H., Park, J., Presta, L. G. and Ferrara, N. (1996). The second immunoglobulin-like domain of the VEGF tyrosine kinase receptor Flt-1 determines ligand binding and may initiate a signal transduction cascade. EMBO J. 15, 4919-4927.
    • (1996) EMBO J. , vol.15 , pp. 4919-4927
    • Davis-Smyth, T.1    Chen, H.2    Park, J.3    Presta, L.G.4    Ferrara, N.5
  • 13
    • 0032192493 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-C: A growth factor for lymphatic and blood vessel endothelial cells
    • Enholm, B., Jussila, L., Karkkainen, M. and Alitalo, K. (1998). Vascular endothelial growth factor-C: A growth factor for lymphatic and blood vessel endothelial cells. Trends Cardiovasc. Med. 8, 292-296
    • (1998) Trends Cardiovasc. Med. , vol.8 , pp. 292-296
    • Enholm, B.1    Jussila, L.2    Karkkainen, M.3    Alitalo, K.4
  • 14
    • 0032559597 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces endothelial fenestrations in vitro
    • Esser, S., Wolburg, K., Wolburg, H., Breier, G., Kurzchalia, T. and Risau, W. (1998). Vascular endothelial growth factor induces endothelial fenestrations in vitro. J. Cell Biol. 140, 947-959.
    • (1998) J. Cell Biol. , vol.140 , pp. 947-959
    • Esser, S.1    Wolburg, K.2    Wolburg, H.3    Breier, G.4    Kurzchalia, T.5    Risau, W.6
  • 17
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • Ferrara, N. and Davis-Smyth, T. (1997). The biology of vascular endothelial growth factor. Endocr. Rev. 18, 4-25.
    • (1997) Endocr. Rev. , vol.18 , pp. 4-25
    • Ferrara, N.1    Davis-Smyth, T.2
  • 18
    • 0029021660 scopus 로고
    • Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
    • Fong, G. H., Rossant, J., Gertsenstein, M. and Breitman, M. L. (1995). Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 376, 66-70.
    • (1995) Nature , vol.376 , pp. 66-70
    • Fong, G.H.1    Rossant, J.2    Gertsenstein, M.3    Breitman, M.L.4
  • 19
    • 0032557564 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells
    • Gerber, H. P., Dixit, V. and Ferrara, N. (1998a). Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells. J. Biol. Chem. 273, 13313-13316.
    • (1998) J. Biol. Chem. , vol.273 , pp. 13313-13316
    • Gerber, H.P.1    Dixit, V.2    Ferrara, N.3
  • 20
    • 0032515047 scopus 로고    scopus 로고
    • VEGF regulates endothelial cell survival by the Pl3-kinase/Akt Signal transduction pathway. Requirement for Flk-1/KDR activation
    • Gerber, H. P., McMurtrey, A., Kowalski, J., Yan, M., Keyt, B., Dixit, V. and Ferrara, N. (1998b). VEGF regulates endothelial cell survival by the Pl3-kinase/Akt Signal transduction pathway. Requirement for Flk-1/KDR activation. J. Biol. Chem. 273, 30336-30345.
    • (1998) J. Biol. Chem. , vol.273 , pp. 30336-30345
    • Gerber, H.P.1    McMurtrey, A.2    Kowalski, J.3    Yan, M.4    Keyt, B.5    Dixit, V.6    Ferrara, N.7
  • 21
    • 0029964835 scopus 로고    scopus 로고
    • A novel method for real time quantitative RT-PCR
    • Gibson, U. E. M., Heid, C. A. and Williams, P. M. (1996). A novel method for real time quantitative RT-PCR. Genome Res. 6, 995-1001
    • (1996) Genome Res. , vol.6 , pp. 995-1001
    • Gibson, U.E.M.1    Heid, C.A.2    Williams, P.M.3
  • 22
    • 0025147371 scopus 로고
    • A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin
    • Good, D., Polverini, P., Rastinejad, F., Beau, M., Lemons, R., Frazier, W. and Bouck, N. (1990). A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin. Proc. Natl. Acad. Sci. USA 87, 6624-6628.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 6624-6628
    • Good, D.1    Polverini, P.2    Rastinejad, F.3    Beau, M.4    Lemons, R.5    Frazier, W.6    Bouck, N.7
  • 23
    • 0028059099 scopus 로고
    • Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
    • Gu, H., Marth, J. D., Orban, P. C., Mossmann, H. and Rajewsky, K. (1994). Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. Science 265, 103-106.
    • (1994) Science , vol.265 , pp. 103-106
    • Gu, H.1    Marth, J.D.2    Orban, P.C.3    Mossmann, H.4    Rajewsky, K.5
  • 26
    • 0032482978 scopus 로고    scopus 로고
    • Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice
    • Hiratsuka, S., Minowa, O., Kuno, J., Noda, T. and Shibuya, M. (1998). Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice. Proc. Natl. Acad Sci. USA 95, 9349-9354.
    • (1998) Proc. Natl. Acad Sci. USA , vol.95 , pp. 9349-9354
    • Hiratsuka, S.1    Minowa, O.2    Kuno, J.3    Noda, T.4    Shibuya, M.5
  • 27
    • 0030270961 scopus 로고    scopus 로고
    • Pericytes in the microvasculature
    • Hirschi, K. K. and D'Amore, P. A. (1996). Pericytes in the microvasculature. Cardiovasc. Res. 32, 687-698.
    • (1996) Cardiovasc. Res. , vol.32 , pp. 687-698
    • Hirschi, K.K.1    D'Amore, P.A.2
  • 30
    • 0026526168 scopus 로고
    • Erythropoietin: Structure, control of production and function
    • Jelkmann, W. (1992). Erythropoietin: structure, control of production and function. Physiol. Rev. 72, 449-489.
    • (1992) Physiol. Rev. , vol.72 , pp. 449-489
    • Jelkmann, W.1
  • 31
    • 0028880305 scopus 로고
    • Expression of the vascular endothelial growth factor (VEGF) receptor gene. KDR, in hematopietic cells and inhibitory effects of VEGF on apoptotic cell death caused by ionizing radiations
    • Katoh, O., Tauchi, H., Kawaishi, K., Kimura, A. and Sarow, Y. (1995). Expression of the vascular endothelial growth factor (VEGF) receptor gene. KDR, in hematopietic cells and inhibitory effects of VEGF on apoptotic cell death caused by ionizing radiations. Cancer Res. 55, 5687-5692.
    • (1995) Cancer Res. , vol.55 , pp. 5687-5692
    • Katoh, O.1    Tauchi, H.2    Kawaishi, K.3    Kimura, A.4    Sarow, Y.5
  • 32
    • 0029920944 scopus 로고    scopus 로고
    • Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors. Generation of receptor-selective VEGF variants by site-directed mutagenesis
    • Keyt, B. A., Nguyen, H. V., Berleau, L. T., Duarte, C. M., Park, J., Chen, H. and Ferrara, N. (1996). Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors. Generation of receptor-selective VEGF variants by site-directed mutagenesis. J. Biol. Chem. 271, 5638-5646.
    • (1996) J. Biol. Chem. , vol.271 , pp. 5638-5646
    • Keyt, B.A.1    Nguyen, H.V.2    Berleau, L.T.3    Duarte, C.M.4    Park, J.5    Chen, H.6    Ferrara, N.7
  • 33
    • 0030927017 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is an essential molecule for mouse kidney development
    • Kitamoto, Y., Tokunaga, H. and Tomita, K. (1997). Vascular endothelial growth factor is an essential molecule for mouse kidney development. J. Clin. Invest. 99, 2351-2357.
    • (1997) J. Clin. Invest. , vol.99 , pp. 2351-2357
    • Kitamoto, Y.1    Tokunaga, H.2    Tomita, K.3
  • 34
    • 0029155706 scopus 로고
    • Inducible gene targeting in mice
    • Kuhn, R., Schwenk, F., Aguet, M. and Rajewsky, K. (1995). Inducible gene targeting in mice. Science 269, 1427-1429.
    • (1995) Science , vol.269 , pp. 1427-1429
    • Kuhn, R.1    Schwenk, F.2    Aguet, M.3    Rajewsky, K.4
  • 35
    • 0027461981 scopus 로고
    • Expression of vascular permeability factor/vascular endothelial growth factor in normal rat tissues
    • Monacci, W. T., Merrill, M. J. and Oldfield, E. H. (1993). Expression of vascular permeability factor/vascular endothelial growth factor in normal rat tissues. Am. J. Physiol. 264, C995-1002.
    • (1993) Am. J. Physiol. , vol.264
    • Monacci, W.T.1    Merrill, M.J.2    Oldfield, E.H.3
  • 36
    • 0031614916 scopus 로고    scopus 로고
    • Simultaneous measurement of cell cycle and apoptotic cell death
    • (ed. J. P. Mather) , Academic Press
    • Moore, A., Donahue, C., Bauer, K. D. and Mather, J. P. (1998). Simultaneous measurement of cell cycle and apoptotic cell death. In Methods in Cell Biology (ed. J. P. Mather) ), pp. 266-278. Academic Press.
    • (1998) Methods in Cell Biology , pp. 266-278
    • Moore, A.1    Donahue, C.2    Bauer, K.D.3    Mather, J.P.4
  • 37
    • 0027474157 scopus 로고
    • The versatility of microvascular pericytes: From mesenchyme to smooth muscle?
    • Nehls, V. and Drenckhahn, D. (1993). The versatility of microvascular pericytes: From mesenchyme to smooth muscle? Histochemistry 99, 1-12.
    • (1993) Histochemistry , vol.99 , pp. 1-12
    • Nehls, V.1    Drenckhahn, D.2
  • 39
  • 40
    • 0030926011 scopus 로고    scopus 로고
    • Implementation of intussusceptive microvascular growth in the chicken chorioallantoic membrane (CAM)
    • Patan, S., Haenni, B. and Burri, P. H. (1997). Implementation of intussusceptive microvascular growth in the chicken chorioallantoic membrane (CAM). Microvasc. Res. 53, 33-52.
    • (1997) Microvasc. Res. , vol.53 , pp. 33-52
    • Patan, S.1    Haenni, B.2    Burri, P.H.3
  • 41
    • 0030856731 scopus 로고    scopus 로고
    • Humanization of an anti-VEGF monoclonal antibody for the therapy of solid tumors and other disorders
    • Presta, L. G., Chen, H., O'Connor, S. J., Chisholm, V., Meng, Y. G., Krummen, L., Winkler, M. and Ferrara, N. (1997). Humanization of an anti-VEGF monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res. 57, 4593-4599.
    • (1997) Cancer Res. , vol.57 , pp. 4593-4599
    • Presta, L.G.1    Chen, H.2    O'Connor, S.J.3    Chisholm, V.4    Meng, Y.G.5    Krummen, L.6    Winkler, M.7    Ferrara, N.8
  • 42
    • 0027249239 scopus 로고
    • Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium
    • Quinn, T. P., Peters, K. G., De Vries, C., Ferrara, N. and Williams, L. T. (1993). Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium. Proc. Natl. Acad. Sci. USA 90, 7533-7637.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 7533-7637
    • Quinn, T.P.1    Peters, K.G.2    De Vries, C.3    Ferrara, N.4    Williams, L.T.5
  • 44
    • 0029112837 scopus 로고
    • Differentiation of endothelium
    • Risau, W. (1995). Differentiation of endothelium. FASEB J. 9, 926-933.
    • (1995) FASEB J. , vol.9 , pp. 926-933
    • Risau, W.1
  • 45
    • 0030952289 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis
    • Risau, W. (1997). Mechanisms of angiogenesis. Nature 386, 671-674.
    • (1997) Nature , vol.386 , pp. 671-674
    • Risau, W.1
  • 46
    • 0029010434 scopus 로고
    • Increased microvascular permeability and endothelial fenestration induced by vascular endothelial growth factor
    • Roberts, W. G. and Palade, G. E. (1995). Increased microvascular permeability and endothelial fenestration induced by vascular endothelial growth factor. J. Cell Sci. 108, 2369-2379.
    • (1995) J. Cell Sci. , vol.108 , pp. 2369-2379
    • Roberts, W.G.1    Palade, G.E.2
  • 47
    • 0028897670 scopus 로고
    • Inhibition of endothelial cell proliferation by SPARC is mediated through a Ca (2+)-binding EF-hand sequence
    • Sage, E. H., Bassuk, J. A., Vost, J. C., Folkman, M. J. and Lane, T. F. (1995). Inhibition of endothelial cell proliferation by SPARC is mediated through a Ca (2+)-binding EF-hand sequence. J. Cell Biochem. 57, 127-140.
    • (1995) J. Cell Biochem. , vol.57 , pp. 127-140
    • Sage, E.H.1    Bassuk, J.A.2    Vost, J.C.3    Folkman, M.J.4    Lane, T.F.5
  • 52
    • 0029949160 scopus 로고    scopus 로고
    • Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody
    • Yuan, F., Chen, Y., Dellian, M., Safabakhsh, N., Ferrara, N. and Jain, R. K. (1996). Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody. Proc. Natl. Acad. Sci. USA 93, 14765-14770.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 14765-14770
    • Yuan, F.1    Chen, Y.2    Dellian, M.3    Safabakhsh, N.4    Ferrara, N.5    Jain, R.K.6


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