Lupin allergy: A hidden killer in the home

Clinical and Experimental Allergy

Volumn 40, Issue 10, 2010, Pages 1461-1466

  Sanz, M L ^a   De Las Marinas, M D ^b   Fernandez J ^c   Gamboa, P M ^d  

^a UNIVERSITY CLINIC OF NAVARRA   (Spain)

^b Unidad de Alergología   (Spain)

^c Elche University Hospital   (Spain)

^d HOSPITAL DE BASURTO   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; CONGLUTININ;

AUSTRALIA; AWARENESS; CONTAMINATION; CROSS ALLERGY; CROSS REACTION; FOOD ALLERGY; FOOD INDUSTRY; HAZARD; HOME ENVIRONMENT; HUMAN; INGESTION; LUPIN; NEW ZEALAND; PATIENT EDUCATION; PEANUT ALLERGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; REGULATORY MECHANISM; RESPONSIBILITY; REVIEW; RISK; SENSITIZATION; UNITED STATES;

ALLERGENS; FABACEAE; FOOD HYPERSENSITIVITY; HUMANS; SEED STORAGE PROTEINS;

EID: 77956532706     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2010.03590.x     Document Type: Review

References (49)

1. Uauy R, Gatas V, Yañez E. Sweet lupins in human nutrition. World Rev Nutr Diet 1995 77 : 75 88.
2. NDA (Scientific Panel on Dietetic Products, Nutrition an Allergies). Opinion of the scientific panel on dietetic, products, nutrition and allergies on a request from the commission related to the evaluation of lupin labelling pruposes. The EFSA Journal 2005 302 : 1 11.
3. Kyprianou M. Commission Directive 2006/142/EC of 22 December 2006 amending Annex IIIa of Directive 2000/13/EC of the European Parliament and of the Council listing the ingredients which must under all circumstances appear on the labelling of foodstuffs. Official Journal of the European Union 2006 L368/110 : 110 111.
4. Reis AM, Fernandes NP, Marques SL et al. Lupine sensitisation in a population of 1,160 subjects. Allergol Immunopathol (Madr) 2007 35 : 162 163.
5. Hita N, Hasan T, Mkinen-Kiljunen S, Lammintausta K. Lupin allergy and lupin sensitization among patients with suspected food allergy. Ann Allergy Asthma Immunol 2009 103 : 233 237.
6. Gayraud J, Mairesse M, Fontaine JF et al. The prevalence of sensitization to lupin flour in France and Belgium: a prospective study in 5366 patients, by the allergy vigilance network. Eur Ann Allergy Clin Immunol 2009 41 : 17 22.
7. Peeters KIA, Koopelman SJ, Penninks AH et al. Clinical relevance of sensitization to lupine in peanut sensitized adults. Allergy 2009 64 : 549 555.
8. Jappe U, Vieths S. Lupine, a source of new as well as hidden food allergens. Mol Nutr Food Res 2010 54 : 113 126.
9. Blagrove RJ, Gillespie MJ. Isolation, purification and characterization of the seed globulins of Lupinus angustifolius. Aust J Plant Physiol 1975 2 : 13 27.
10. Melo TS, Ferreira RB, Teixeira AN. The seed storage proteins from Lupinus albus. Phytochemistry 1994 37 : 641 648.
11. Holden L, Sletten GB, Lindvik H, Faeste CK, Dooper MMBW. Characterization of IgE binding to lupin, peanut and almond with sera from lupin-allergic patients. Int Arch Allergy Immunol 2008 146 : 267 276.
12. Goggin DE, Mir G, Smith WB, Stuckey M, Smith PMC. Proteomic Analysis of lupin seed proteins to identify conglutin beta as an allergen, Lup an 1. J Agric Food Chem 2008 56 : 6370 6377.
13. Guarneri F, Guarneri C, Benvenga S. Identification of potencially cross-reactive peanut-lupine proteins by computer-assisted search for amino acid sequence homology. Int Arch Allergy Immunol 2005 138 : 273 277.
14. Rojas Hijazo B, Garcés MM, Caballero ML, Alloza P, Moneo I. Unsuspected lupin allergens hidden in food. Int Arch Allergy Immunol 2006 141 : 47 50.
15. De las Marinas D, Cojocariu Z, Escudero R, Pardo N, Sanz ML. Anaphylaxis induced by lupine as a hidden allergen. J Investig Allergol Clin Immunol 2007 17 : 283 284.
16. Peeters KA, Nordlle JA, Penninks AH et al. Lupine allergy: not simply cross-reactivity with peanut or soy. J Allergy Clin Immunol 2007 120 : 647 653.
17. Quaresma RR, Viseu R, Martins LM, Tomaz E, Inácio F. Allergic primary sensitization to lupine seed. Allergy 2007 62 : 1473 1474.
18. Castro A, Lara P, Galindo P, Borja J, Ledesma A, Feo F. Alergia a altramuz como alérgeno oculto. J Investig Allergol Clin Immunol 2008 18 : 194.
19. Santos S, Bartolomé B, González D, Trujillo M, Meléndez A, González E. Anafilaxia tras ingesta de bizcocho (Brownie). J Investig Allergol Clin Immunol 2008 18 : 195.
20. Hefle SL, Lemanske RF JR, Bush RK. Adverse reaction to lupine-fortified pasta. J Allergy Clin Immunol 1994 94 : 167 172.
21. Guillamón E, Rodríguez J, Burbano C et al. Characterization of lupin major allergens (Lupinus albus L.). Mol Nutr Food Res 2010 54 : 1 9.
22. Barre A, Borges JP, Culerrier R, Rouge P. Homology modelling of the major peanut allergen Ara h 2 and surface mapping of IgE binding epitopes. Immunol Lett 2005 100 : 153 158.
23. Romano C, Ferrara A, Tarallos S. Allergic reaction to lupine seed (Lupinus albus). Allergy 1997 52 : 113 114.
24. Leduc V, Moneret-Vautrin DA, Guérin L Alergenicity de la farine de lupin. Allerg Immunol (Paris) 2002 34 : 213 217.
25. Smith WB, Gillis D, Kette FE. Lupin: a new hidden food allergen. Med J Aust 2004 181 : 219 220.
26. Rotiroti G, Skypala I, Senna G, Passalacqua G. Anaphylaxis due to lupine flour in a celiac patient. J Investig Allergol Clin Immunol 2007 17 : 204 205.
27. Wassenberg J, Hofer M. Lupine-induced anaphylaxis in a child without known food allergy. Ann Allergy Asthma Immunol 2007 98 : 589 590.
28. Brennecke S, Becker WM, Lepp U, Jappe U. Anaphylactic reaction to lupine flour. J Dtsch Dermathol Ges 2007 5 : 774 776.
29. Wüthrich B. Anaphylactic reaction to lupine flour because of a primary sensitization. Allergy 2008 63 : 476 477.
30. Rossi G, Amato S, Mistrello G. Gluten-free food as source of hidden allergen (lupine). Eur Ann Allergy Clin Immunol 2009 41 : 123 125.
31. Crespo JF, Rodríguez J, Vives R et al. Occupational IgE mediated allergy after exposure to lupine seed flour. J Allergy Clin Immunol 2001 108 : 295 297.
32. Parisot L, Aparicio C, Moneret-Vautrin DA, Guérin L. Allergy to lupin flour. Allergy 2001 56 : 918 919.
33. Campbell CP, Jackson AS, Johnson AR, Thomas PS, Yates DH. Occupational sensitization to lupin in the workplace: occupational asthma, rhinitis and work-aggravated asthma. J Allergy Clin Immunol 2007 119 : 1133 1139.
34. Prieto A, Razzak E, Lindo DP, Alvarez-Perea A, Rueda M, Baeza ML. Recurrent Anaphylaxis due to lupin flour: primary sensitization through inhalation. J Ivestig Allergol Clin Immunol 2010 20 : 76 9.
35. Ibañez MD, Martinez M, Sanchez JJ, Fernandez de Caldas E Legume cross-reactivity. Allergol Immunopathol (Madr) 2003 31 : 151 161.
36. Kanny G, Guérin L, Moneret-Vautrin DA. Risk of serious acute asthma due to lupine flour associated with peanut allergy. Rev Med Interne 2000 21 : 191 194.
37. Faeste CK, Lovik M, Wike HG, Egaas E. A case of peanut cross-allergy to lupine flour in a hot dog bread. Int Arch Allergy Immunol 2004 135 : 36 9.
38. Wüthrich B, Mitag D, Ballmer-Weber BK. Die pizza: eine quelle von unerwarteten allergenen-anaphylaktische reaktion auf lupinenmehl im pizzateig und in einem lebkuchen. Allergologie 2004 27 : 495 502.
39. Radcliffe M, Scadding G, Brown HM. Lupin flour anaphylaxis. Lancet 2005 365 : 1360.
40. Moreno-Ancillo A, Gil-Adrados AC, Domínguez-Noche C, Cosmes PM. Lupine inhalation induced asthma in a child. Pediatr Allergy Immunol 2005 16 : 542 544.
41. Shaw J, Roberts G, Grimshaw K, White S, Hourihane J. Lupin allergy in peanut-allergic children and teenagers. Allergy 2008 63 : 370 373.
42. Matheu V, de Barrio M, Sierra Z, Gracia-Bara MT, Tornero P, Baeza ML. Lupine-induced anaphylaxis. Ann Allergy Asthma Immunol 1999 83 : 406 408.
43. Lindvick H, Holden L, Cvancarova M, Halvorsen R. Lupin sensitization and clinical allergy in food allergic children in Norway. Acta Paediatr 2008 97 : 91 5.
44. Holden L, Faeste CK, Egaas E. Quantitative sándwich ELISA for the determination of lupine (Lupinus spp) in foods. J Agr Food Chem 2005 53 : 5866 5871.
45. Holden L, Moen LH, Sletten GB, Dooper MM. Novel polyclonal-monoclonal- based ELISA utilized to examine lupine (Lupinus species) content in food products. J Agr Food Chem 2007 55 : 2536 2542.
46. Demmel A, Hupfer C, Iil Hampe E, Busch U, Engel KH. Development of a real-time PCR for the detection of lupine DNA (lupines species) in foods. J Agr Food Chem 2008 56 : 4328 4332.
47. Moneret-Vautrin DA, Guérin L, Kanny G, Flabbee J, Frémont S, Morisset M. Cross-allergenicity of peanut and lupine: the risk of lupine allergy in patients allergic to peanuts. J Allergy Clin Immunol 1999 104 (Part 1) : 883 888.
48. Jensen LB, Anderssen M, Skow PS, Poulsen LK, Bindeslev-Jensen C. Risk assessment of clinical reaction to legume in peanut-allergic children. WAO J 2008 1 : 162 167.
49. Guillamón E, Burbano C, Cuadrado C et al. Effect of an instataneous controlled pressure drop on in vitro allergenicity to lupinus (Lupinus albus var Multolupa). Int Arch Allergy Immunol 2008 145 : 9 14.