-
1
-
-
0034711258
-
Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes
-
Oda T, Morikawa N, Saito Y, Masuho Y, Matsumoto S. Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes. J Biol Chem 2000, 275(47): 36781-6.
-
(2000)
J Biol Chem
, vol.275
, Issue.47
, pp. 36781-36786
-
-
Oda, T.1
Morikawa, N.2
Saito, Y.3
Masuho, Y.4
Matsumoto, S.5
-
2
-
-
0035126496
-
Cloning and pharmacological characterization of a fourth histamine receptor (H4) expressed in bone marrow
-
Liu C, Ma X-J, Jiang X. et al. Cloning and pharmacological characterization of a fourth histamine receptor (H4) expressed in bone marrow. Mol Pharmacol 2001, 59(3): 420-6.
-
(2001)
Mol Pharmacol
, vol.59
, Issue.3
, pp. 420-426
-
-
Liu, C.1
Ma, X.-J.2
Jiang, X.3
-
3
-
-
0035120049
-
Cloning and characterization of a novel human histamine receptor
-
Morse KL, Behan J, Laz T. M. et al. Cloning and characterization of a novel human histamine receptor. J Pharmacol Exp Ther 2001, 296(3): 1058-66.
-
(2001)
J Pharmacol Exp Ther
, vol.296
, Issue.3
, pp. 1058-1066
-
-
Morse, K.L.1
Behan, J.2
Laz, T.M.3
-
4
-
-
0035123167
-
Discovery of a novel member of the histamine receptor family
-
Nguyen T, Shapiro DA, George SR. et al. Discovery of a novel member of the histamine receptor family. Mol Pharmacol 2001, 59(3): 427-33. (Pubitemid 32179919)
-
(2001)
Molecular Pharmacology
, vol.59
, Issue.3
, pp. 427-433
-
-
Nguyen, T.1
Shapiro, D.A.2
George, S.R.3
Setola, V.4
Lee, D.K.5
Cheng, R.6
Rauser, L.7
Lee, S.P.8
Lynch, K.R.9
Roth, B.L.10
O'Dowd, B.F.11
-
5
-
-
0035126498
-
Cloning, expression, and pharmacological characterization of a novel human histamine receptor
-
Zhu, Y, Michalovich D, Wu H-L. et al. Cloning, expression, and pharmacological characterization of a novel human histamine receptor. Mol Pharmacol 2001, 59(3), 434-41.
-
(2001)
Mol Pharmacol
, vol.59
, Issue.3
, pp. 434-441
-
-
Zhu, Y.1
Michalovich, D.2
Wu, H.-L.3
-
6
-
-
0038324003
-
Histamine H4 receptor mediates chemotaxis and calcium mobilization of mast cells
-
Hofstra CL, Desai PJ, Thurmond RL, Fung-Leung W-P. Histamine H4 receptor mediates chemotaxis and calcium mobilization of mast cells. J Pharmacol Exp Ther 2003, 305(3): 1212-21.
-
(2003)
J Pharmacol Exp Ther
, vol.305
, Issue.3
, pp. 1212-1221
-
-
Hofstra, C.L.1
Desai, P.J.2
Thurmond, R.L.3
Fung-Leung, W.-P.4
-
7
-
-
0036978843
-
Identification of a histamine H4 receptor on human eosinophils-role in eosinophil chemotaxis
-
O'Reilly M, Alpert R, Jenkinson S. et al. Identification of a histamine H4 receptor on human eosinophils-role in eosinophil chemotaxis. J Recept Signal Transduct Res 2002, 22(1-4) 431-48.
-
(2002)
J Recept Signal Transduct Res
, vol.22
, Issue.1-4
, pp. 431-448
-
-
O'Reilly, M.1
Alpert, R.2
Jenkinson, S.3
-
8
-
-
0344826048
-
Histamine induces cytoskeletal changes in human eosinophils via the H4 receptor
-
Buckland KF, Williams TJ, Conroy DM. Histamine induces cytoskeletal changes in human eosinophils via the H4 receptor. Br J Pharmacol 2003, 140(6): 1117-27.
-
(2003)
Br J Pharmacol
, vol.140
, Issue.6
, pp. 1117-1127
-
-
Buckland, K.F.1
Williams, T.J.2
Conroy, D.M.3
-
9
-
-
17844385099
-
Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells
-
Gutzmer R, Diestel C, Mommert S. et al. Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells. J Immunol 2005, 174(9): 5224-32.
-
(2005)
J Immunol
, vol.174
, Issue.9
, pp. 5224-5232
-
-
Gutzmer, R.1
Diestel, C.2
Mommert, S.3
-
10
-
-
33646857548
-
The histamine H4 receptor mediates allergic airway inflammation by regulating the activation of CD4+T cells
-
Dunford PJ, O'Donnell N, Riley JP, Williams KN, Karlsson L, Thurmond RL. The histamine H4 receptor mediates allergic airway inflammation by regulating the activation of CD4+T cells. J Immunol 2006, 176(11): 7062-70.
-
(2006)
J Immunol
, vol.176
, Issue.11
, pp. 7062-7070
-
-
Dunford, P.J.1
O'Donnell, N.2
Riley, J.P.3
Williams, K.N.4
Karlsson, L.5
Thurmond, R.L.6
-
11
-
-
0036784498
-
Histamine H(4) and H(2) receptors control histamine-induced Interleukin-16 release from human CD8(+) T cells
-
Gantner F, Sakai K, Tusche MW, Cruikshank WW, Center DM, Bacon KB. Histamine H(4) and H(2) receptors control histamine-induced Interleukin-16 release from human CD8(+) T cells. J Pharmacol Exp Ther 2002, 303(1): 300-7.
-
(2002)
J Pharmacol Exp Ther
, vol.303
, Issue.1
, pp. 300-307
-
-
Gantner, F.1
Sakai, K.2
Tusche, M.W.3
Cruikshank, W.W.4
Center, D.M.5
Bacon, K.B.6
-
12
-
-
34547092690
-
Histamine downregulates monocyte CCL2 production through the histamine H4 receptor
-
Dijkstra D, Leurs R, Chazot P. et al. Histamine downregulates monocyte CCL2 production through the histamine H4 receptor. J Allergy Clin Immunol 2007, 120(2): 300-7.
-
(2007)
J Allergy Clin Immunol
, vol.120
, Issue.2
, pp. 300-307
-
-
Dijkstra, D.1
Leurs, R.2
Chazot, P.3
-
13
-
-
34548319667
-
Histamine excites neurones in the human submucous plexus through activation of H1 H2, H3 and H4 receptors
-
Breunig E, Michel K, Zeller F, Seidl S, Hann v. Weyhern CW, Schemann M. Histamine excites neurones in the human submucous plexus through activation of H1, H2, H3 and H4 receptors. J Physiol 2007, 583(Pt. 2): 731-42.
-
(2007)
J Physiol
, vol.583
, Issue.PART 2
, pp. 731-742
-
-
Breunig, E.1
Michel, K.2
Zeller, F.3
Seidl, S.4
Hann, V.5
Weyhern, C.W.6
Schemann, M.7
-
14
-
-
2542530713
-
Histamine H4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation
-
Ling P, Ngo K, Nguyen S. et al. Histamine H4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation. Br J Pharmacol 2004, 142(1): 161-71.
-
(2004)
Br J Pharmacol
, vol.142
, Issue.1
, pp. 161-171
-
-
Ling, P.1
Ngo, K.2
Nguyen, S.3
-
15
-
-
33745192634
-
The H1 histamine receptor regulates allergic lung responses
-
Bryce PJ, Mathias CB, Harrison KL, Watanabe T, Geha RS, Oettgen HC. The H1 histamine receptor regulates allergic lung responses. J Clin Invest 2006, 116(6): 1624-32.
-
(2006)
J Clin Invest
, vol.116
, Issue.6
, pp. 1624-1632
-
-
Bryce, P.J.1
Mathias, C.B.2
Harrison, K.L.3
Watanabe, T.4
Geha, R.S.5
Oettgen, H.C.6
-
16
-
-
34250180480
-
Histamine 4 receptor activation induces recruitment of Foxp3+ T cells and inhibits allergic asthma in a murine model
-
Morgan RK, McAllister B, Cross L. et al. Histamine 4 receptor activation induces recruitment of Foxp3+ T cells and inhibits allergic asthma in a murine model. J Immunol 2007, 178(12): 8081-9.
-
(2007)
J Immunol
, vol.178
, Issue.12
, pp. 8081-8089
-
-
Morgan, R.K.1
McAllister, B.2
Cross, L.3
-
17
-
-
85004912647
-
Measurement of plasma histamine in asthma
-
Ind P, Barnes P, Brown M, Causon R, Dollery C. Measurement of plasma histamine in asthma. Clin Allergy 1983, 13(1): 61-7.
-
(1983)
Clin Allergy
, vol.13
, Issue.1
, pp. 61-67
-
-
Ind, P.1
Barnes, P.2
Brown, M.3
Causon, R.4
Dollery, C.5
-
18
-
-
0025837891
-
Immediate and late inflammatory responses to ragweed antigen challenge of the peripheral airways in allergic asthmatics Cellular, mediator, and permeability changes
-
Liu MC, Hubbard WC, Proud D. et al. Immediate and late inflammatory responses to ragweed antigen challenge of the peripheral airways in allergic asthmatics. Cellular, mediator, and permeability changes. Am Rev Resp Dis 1991, 144(1): 51-8.
-
(1991)
Am Rev Resp Dis
, vol.144
, Issue.1
, pp. 51-58
-
-
Liu, M.C.1
Hubbard, W.C.2
Proud, D.3
-
19
-
-
0023195578
-
Elevated bronchoalveolar lavage fluid histamine levels in allergic asthmatics are associated with methacholine bronchial hyperresponsiveness
-
Casale TB, Wood D, Richerson HB. et al. Elevated bronchoalveolar lavage fluid histamine levels in allergic asthmatics are associated with methacholine bronchial hyperresponsiveness. J Clin Invest 1987, 79(4): 1197-203.
-
(1987)
J Clin Invest
, vol.79
, Issue.4
, pp. 1197-1203
-
-
Casale, T.B.1
Wood, D.2
Richerson, H.B.3
-
20
-
-
0023831561
-
Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma Relationship to bronchial hyperreactivity
-
Wardlaw AJ, Dunnette S, Gleich GJ, Collins JV, Kay AB. Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma. Relationship to bronchial hyperreactivity. Am Rev Resp Dis 1988, 137(1): 62-9.
-
(1988)
Am Rev Resp Dis
, vol.137
, Issue.1
, pp. 62-69
-
-
Wardlaw, A.J.1
Dunnette, S.2
Gleich, G.J.3
Collins, J.V.4
Kay, A.B.5
-
21
-
-
0025913012
-
Elevated bronchoalveolar lavage fluid histamine levels in allergic asthmatics are associated with increased airway obstruction
-
Jarjour N, Calhoun W, Schwartz L, Busse W. Elevated bronchoalveolar lavage fluid histamine levels in allergic asthmatics are associated with increased airway obstruction. Am Rev Resp Dis 1991, 144(1): 83-7.
-
(1991)
Am Rev Resp Dis
, vol.144
, Issue.1
, pp. 83-87
-
-
Jarjour, N.1
Calhoun, W.2
Schwartz, L.3
Busse, W.4
-
22
-
-
0024565464
-
Spontaneous histamine release and histamine content in normal subjects and subjects with asthma
-
Akagi K, Townley RG. Spontaneous histamine release and histamine content in normal subjects and subjects with asthma. J Allergy Clin Immunol 1989, 83(4): 742-9.
-
(1989)
J Allergy Clin Immunol
, vol.83
, Issue.4
, pp. 742-749
-
-
Akagi, K.1
Townley, R.G.2
-
23
-
-
12144288036
-
A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties
-
Thurmond RL, Desai PJ, Dunford PJ. et al. A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties. J Pharmacol Exp Ther 2004, 309(1): 404-13.
-
(2004)
J Pharmacol Exp Ther
, vol.309
, Issue.1
, pp. 404-413
-
-
Thurmond, R.L.1
Desai, P.J.2
Dunford, P.J.3
-
24
-
-
0345167199
-
Critical role of histamine H4 receptor in leukotriene b4 production and mast cell-dependent neutrophil recruitment induced by zymosan in vivo
-
Takeshita K, Sakai K, Bacon KB, Gantner F. Critical role of histamine H4 receptor in leukotriene b4 production and mast cell-dependent neutrophil recruitment induced by zymosan in vivo. J Pharmacol Exp Ther 2003, 307(3): 1072-8.
-
(2003)
J Pharmacol Exp Ther
, vol.307
, Issue.3
, pp. 1072-1078
-
-
Takeshita, K.1
Sakai, K.2
Bacon, K.B.3
Gantner, F.4
-
25
-
-
26844504964
-
Inhibitory effects of histamine H4 receptor antagonists on experimental colitis in the rat
-
Varga C, Horvath K, Berko A, Thurmond RL, Dunford PJ, Whittle BJ. Inhibitory effects of histamine H4 receptor antagonists on experimental colitis in the rat. Eur J Pharmacol 2005, 522(1-3): 130-8.
-
(2005)
Eur J Pharmacol
, vol.522
, Issue.1-3
, pp. 130-138
-
-
Varga, C.1
Horvath, K.2
Berko, A.3
Thurmond, R.L.4
Dunford, P.J.5
Whittle, B.J.6
-
26
-
-
34247137952
-
Antiinflammatory and antinociceptive effects of the selective histamine H4-receptor antagonists JNJ7777120 and VUF6002 in a rat model of carrageenan-induced acute inflammation
-
Coruzzi G, Adami M, Guaita E, de Esch I. JP, Leurs R. Antiinflammatory and antinociceptive effects of the selective histamine H4-receptor antagonists JNJ7777120 and VUF6002 in a rat model of carrageenan-induced acute inflammation. Eur J Pharmacol 2007, 563(1-3): 240-4.
-
(2007)
Eur J Pharmacol
, vol.563
, Issue.1-3
, pp. 240-244
-
-
Coruzzi, G.1
Adami, M.2
Guaita, E.3
De Esch, I.J.P.4
Leurs, R.5
-
27
-
-
3142617894
-
Immunohistochemical localization of histamine receptor subtypes in human inferior turbinates
-
Nakaya M, Takeuchi N, Kondo K. Immunohistochemical localization of histamine receptor subtypes in human inferior turbinates. Ann Otol Rhinol Laryngol 2004, 113(7): 552-7.
-
(2004)
Ann Otol Rhinol Laryngol
, vol.113
, Issue.7
, pp. 552-557
-
-
Nakaya, M.1
Takeuchi, N.2
Kondo, K.3
-
28
-
-
33845924770
-
Histamine H4 receptor antagonists are superior to traditional antihistamines in the attenuation of experimental pruritus
-
Dunford PJ, Williams KN, Desai PJ, Karlsson L, McQueen D, Thurmond RL. Histamine H4 receptor antagonists are superior to traditional antihistamines in the attenuation of experimental pruritus. J Allergy Clin Immunol 2007, 119(1): 176-83.
-
(2007)
J Allergy Clin Immunol
, vol.119
, Issue.1
, pp. 176-183
-
-
Dunford, P.J.1
Williams, K.N.2
Desai, P.J.3
Karlsson, L.4
McQueen, D.5
Thurmond, R.L.6
-
29
-
-
1242320992
-
Cough is an airway itch?
-
Gibson PG. Cough is an airway itch? Am J Respir Crit Care Med 2004, 169(1): 1-2.
-
(2004)
Am J Respir Crit Care Med
, vol.169
, Issue.1
, pp. 1-2
-
-
Gibson, P.G.1
-
30
-
-
0141455895
-
The first potent and selective nonimidazole human histamine H4 receptor antagonists
-
Jablonowski JA, Grice CA, Chai W. et al. The first potent and selective nonimidazole human histamine H4 receptor antagonists. J Med Chem 2003, 46(19): 3957-60.
-
(2003)
J Med Chem
, vol.46
, Issue.19
, pp. 3957-3960
-
-
Jablonowski, J.A.1
Grice, C.A.2
Chai, W.3
-
31
-
-
29744441372
-
Preparation and biological evaluation of indole, benzimidazole, and thienopyrrole piperazine carboxamides: Potent human histamine H(4) antagonists
-
Venable JD, Cai H, Chai W. et al. Preparation and biological evaluation of indole, benzimidazole, and thienopyrrole piperazine carboxamides: Potent human histamine H(4) antagonists. J Med Chem 2005, 48(26): 8289-98.
-
(2005)
J Med Chem
, vol.48
, Issue.26
, pp. 8289-8298
-
-
Venable, J.D.1
Cai, H.2
Chai, W.3
-
32
-
-
5344236080
-
Synthesis and structure-activity relationships of indole and benzimidazole piperazines as histamine H(4) receptor antagonists
-
Terzioglu N, van Rijn RM, Bakker RA, De Esch IJ, Leurs R. Synthesis and structure-activity relationships of indole and benzimidazole piperazines as histamine H(4) receptor antagonists. Bioorg Med Chem Lett 2004, 14(12): 5251-6.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, Issue.12
, pp. 5251-5256
-
-
Terzioglu, N.1
Van Rijn, R.M.2
Bakker, R.A.3
De Esch, I.J.4
Leurs, R.5
-
33
-
-
4344613960
-
Arthropod-derived histamine-binding protein prevents murine allergic asthma
-
Couillin I, Maillet I, Vargaftig BB. et al. Arthropod-derived histamine-binding protein prevents murine allergic asthma. J Immunol 2004, 173(5): 3281-6.
-
(2004)
J Immunol
, vol.173
, Issue.5
, pp. 3281-3286
-
-
Couillin, I.1
Maillet, I.2
Vargaftig, B.B.3
-
34
-
-
33750956816
-
-
(Bayer Healthcare AG) WO 2005014556, February 17
-
Sato H, Fukushima K, Shimazaki M. et al. (Bayer Healthcare AG). Preparation of 2-aminopyrimidine derivatives, useful as histamine H4 receptor antagonists. WO 2005014556, February 17, 2005.
-
(2005)
Preparation of 2-aminopyrimidine Derivatives, Useful As Histamine H4 Receptor Antagonists
-
-
Sato, H.1
Fukushima, K.2
Shimazaki, M.3
-
35
-
-
77956461084
-
-
(Argenta Discovery Ltd.) WO 2006050965, May 18
-
Harris N, Higgs C, Wren S, Dyke H, Price, S, Cramp S. (Argenta Discovery Ltd.) Preparation of fused pyrimidine compounds as histamine H4 modulators. WO 2006050965, May 18, 2006.
-
(2006)
Preparation of Fused Pyrimidine Compounds As Histamine H4 Modulators
-
-
Harris, N.1
Higgs, C.2
Wren, S.3
Dyke, H.4
Price, S.5
Cramp, S.6
-
36
-
-
33750508934
-
Identification of 2-arylbenzimidazoles as potent human histamine H4 receptor ligands
-
Lee-Dutra A, Arienti KL, Buzard DJ. et al. Identification of 2-arylbenzimidazoles as potent human histamine H4 receptor ligands. Bioorg Med Chem Lett 2006, 16(23): 6043-8.
-
(2006)
Bioorg Med Chem Lett
, vol.16
, Issue.23
, pp. 6043-6048
-
-
Lee-Dutra, A.1
Arienti, K.L.2
Buzard, D.J.3
-
37
-
-
77956488577
-
Histamine H4 receptor antagonism modulates eosinophil and mast cell chemotaxis and attenuates allergic airway inflammation
-
[101st Int Conf Am Thorac Soc (May 20-25, San Diego) 2005]
-
Dunford PJ, Thurmond RL, Fung-Leung W-P, Karlsson L. Histamine H4 receptor antagonism modulates eosinophil and mast cell chemotaxis and attenuates allergic airway inflammation. Proc Am Thorac Soc [101st Int Conf Am Thorac Soc (May 20-25, San Diego) 2005] 2005, A906.
-
(2005)
Proc Am Thorac Soc
-
-
Dunford, P.J.1
Thurmond, R.L.2
Fung-Leung, W.-P.3
Karlsson, L.4
-
38
-
-
77956465937
-
Selective histamine H4 receptor antagonism modulates IL13 driven remodeling in a chronic mouse asthma model
-
[103rd Int Conf Am Thorac Soc (May 18-23, San Francisco) 2007]
-
Cowden J, Riley J, Williams KN, Thurmond RL, Dunford PJ. Selective histamine H4 receptor antagonism modulates IL13 driven remodeling in a chronic mouse asthma model. Proc Am Thorac Soc [103rd Int Conf Am Thorac Soc (May 18-23, San Francisco) 2007] 2007, A204.
-
(2007)
Proc Am Thorac Soc
-
-
Cowden, J.1
Riley, J.2
Williams, K.N.3
Thurmond, R.L.4
Dunford, P.J.5
-
39
-
-
77956466217
-
Vivo efficacy of the selective H4 antagonist JNJ 7777120 in a sephadex model of pulmonary eosinophilia
-
Abst122P
-
Douglas G, Brown C, Liu W. In vivo efficacy of the selective H4 antagonist JNJ 7777120 in a sephadex model of pulmonary eosinophilia. Br Pharmacol Soc Winter Meet (London) 2005, Abst122P.
-
(2005)
Br Pharmacol Soc Winter Meet (London)
-
-
Douglas, G.1
Brown, C.2
Liu, W.3
-
40
-
-
2942530381
-
Involvement of histamine H4 and H1 receptors in scratching induced by histamine receptor agonists in balb c mice
-
Bell JK, McQueen DS, Rees JL. Involvement of histamine H4 and H1 receptors in scratching induced by histamine receptor agonists in balb c mice. Br J Pharmacol 2004, 142(2): 374-80.
-
(2004)
Br J Pharmacol
, vol.142
, Issue.2
, pp. 374-380
-
-
Bell, J.K.1
McQueen, D.S.2
Rees, J.L.3
|