-
1
-
-
0036715411
-
Immature, semi-mature and fully mature dendritic cells: Which signals induce tolerance or immunity?
-
Lutz MB, Schuler G (2002) Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity? Trends Immunol 23: 445-449.
-
(2002)
Trends Immunol
, vol.23
, pp. 445-449
-
-
Lutz, M.B.1
Schuler, G.2
-
2
-
-
34247093900
-
Interdependency of MHC class II/self-peptide and CD1d/self-glycolipid presentation by TNF-matured dendritic cells for protection from autoimmunity
-
Wiethe C, Schiemann M, Busch D, Haeberle L, Kopf M, et al. (2007) Interdependency of MHC class II/self-peptide and CD1d/self-glycolipid presentation by TNF-matured dendritic cells for protection from autoimmunity. J Immunol 178: 4908-4916.
-
(2007)
J Immunol
, vol.178
, pp. 4908-4916
-
-
Wiethe, C.1
Schiemann, M.2
Busch, D.3
Haeberle, L.4
Kopf, M.5
-
3
-
-
0037033427
-
Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity
-
Menges M, Rossner S, Voigtlander C, Schindler H, Kukutsch NA, et al. (2002) Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity. J Exp Med 195: 15-21.
-
(2002)
J Exp Med
, vol.195
, pp. 15-21
-
-
Menges, M.1
Rossner, S.2
Voigtlander, C.3
Schindler, H.4
Kukutsch, N.A.5
-
4
-
-
0036548986
-
Spinning molecular immunology into successful immunotherapy
-
Pardoll DM (2002) Spinning molecular immunology into successful immunotherapy. Nat Rev Immunol 2: 227-238.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 227-238
-
-
Pardoll, D.M.1
-
5
-
-
21644446452
-
Therapeutic opportunities in the B7/CD28 family of ligands and receptors
-
Carreno BM, Carter LL, Collins M (2005) Therapeutic opportunities in the B7/CD28 family of ligands and receptors. Curr Opin Pharmacol 5: 424-430.
-
(2005)
Curr Opin Pharmacol
, vol.5
, pp. 424-430
-
-
Carreno, B.M.1
Carter, L.L.2
Collins, M.3
-
6
-
-
3242677686
-
PD-L1- deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells
-
Latchman YE, Liang SC, Wu Y, Chernova T, Sobel RA, et al. (2004) PD-L1- deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells. Proc Natl Acad Sci U S A 101: 10691-10696.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 10691-10696
-
-
Latchman, Y.E.1
Liang, S.C.2
Wu, Y.3
Chernova, T.4
Sobel, R.A.5
-
7
-
-
0038185203
-
Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction
-
Wang S, Bajorath J, Flies DB, Dong H, Honjo T, et al. (2003) Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction. J Exp Med 197: 1083-1091.
-
(2003)
J Exp Med
, vol.197
, pp. 1083-1091
-
-
Wang, S.1
Bajorath, J.2
Flies, D.B.3
Dong, H.4
Honjo, T.5
-
8
-
-
34447646310
-
Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses
-
Butte MJ, Keir ME, Phamduy TB, Sharpe AH, Freeman GJ (2007) Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses. Immunity 27: 111-122.
-
(2007)
Immunity
, vol.27
, pp. 111-122
-
-
Butte, M.J.1
Keir, M.E.2
Phamduy, T.B.3
Sharpe, A.H.4
Freeman, G.J.5
-
9
-
-
0037111483
-
Expression of programmed death 1 ligands by murine T cells and APC
-
Yamazaki T, Akiba H, Iwai H, Matsuda H, Aoki M, et al. (2002) Expression of programmed death 1 ligands by murine T cells and APC. J Immunol 169: 5538-5545.
-
(2002)
J Immunol
, vol.169
, pp. 5538-5545
-
-
Yamazaki, T.1
Akiba, H.2
Iwai, H.3
Matsuda, H.4
Aoki, M.5
-
10
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
Freeman GJ, Long AJ, Iwai Y, Bourque K, Chernova T, et al. (2000) Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med 192: 1027-1034.
-
(2000)
J Exp Med
, vol.192
, pp. 1027-1034
-
-
Freeman, G.J.1
Long, A.J.2
Iwai, Y.3
Bourque, K.4
Chernova, T.5
-
12
-
-
20144378485
-
Microglial expression of the B7 family member B7 homolog 1 confers strong immune inhibition: Implications for immune responses and autoimmunity in the CNS
-
Magnus T, Schreiner B, Korn T, Jack C, Guo H, et al. (2005) Microglial expression of the B7 family member B7 homolog 1 confers strong immune inhibition: implications for immune responses and autoimmunity in the CNS. J Neurosci 25: 2537-2546.
-
(2005)
J Neurosci
, vol.25
, pp. 2537-2546
-
-
Magnus, T.1
Schreiner, B.2
Korn, T.3
Jack, C.4
Guo, H.5
-
13
-
-
33845456174
-
Cutting Edge: Programmed death (PD) ligand-1/PD-1 interaction is required for CD8+ T cell tolerance to tissue antigens
-
Martin-Orozco N, Wang YH, Yagita H, Dong C (2006) Cutting Edge: Programmed death (PD) ligand-1/PD-1 interaction is required for CD8+ T cell tolerance to tissue antigens. J Immunol 177: 8291-8295.
-
(2006)
J Immunol
, vol.177
, pp. 8291-8295
-
-
Martin-Orozco, N.1
Wang, Y.H.2
Yagita, H.3
Dong, C.4
-
14
-
-
34247884612
-
The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
-
Sharpe AH, Wherry EJ, Ahmed R, Freeman GJ (2007) The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection. Nat Immunol 8: 239-245.
-
(2007)
Nat Immunol
, vol.8
, pp. 239-245
-
-
Sharpe, A.H.1
Wherry, E.J.2
Ahmed, R.3
Freeman, G.J.4
-
15
-
-
33846018451
-
PD-1/PDL1, but not PD-1/PD-L2, interactions regulate the severity of experimental autoimmune encephalomyelitis
-
Carter LL, Leach MW, Azoitei ML, Cui J, Pelker JW, et al. (2007) PD-1/PDL1, but not PD-1/PD-L2, interactions regulate the severity of experimental autoimmune encephalomyelitis. J Neuroimmunol 182: 124-134.
-
(2007)
J Neuroimmunol
, vol.182
, pp. 124-134
-
-
Carter, L.L.1
Leach, M.W.2
Azoitei, M.L.3
Cui, J.4
Pelker, J.W.5
-
16
-
-
0032736029
-
B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion
-
Dong H, Zhu G, Tamada K, Chen L (1999) B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat Med 5: 1365-1369.
-
(1999)
Nat Med
, vol.5
, pp. 1365-1369
-
-
Dong, H.1
Zhu, G.2
Tamada, K.3
Chen, L.4
-
17
-
-
0036207926
-
PD-1:PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2
-
Carter L, Fouser LA, Jussif J, Fitz L, Deng B, et al. (2002) PD-1:PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2. Eur J Immunol 32: 634-643.
-
(2002)
Eur J Immunol
, vol.32
, pp. 634-643
-
-
Carter, L.1
Fouser, L.A.2
Jussif, J.3
Fitz, L.4
Deng, B.5
-
18
-
-
0242559053
-
Endothelial expression of PD-L1 and PD-L2 down-regulates CD8+ T cell activation and cytolysis
-
Rodig N, Ryan T, Allen JA, Pang H, Grabie N, et al. (2003) Endothelial expression of PD-L1 and PD-L2 down-regulates CD8+ T cell activation and cytolysis. Eur J Immunol 33: 3117-3126.
-
(2003)
Eur J Immunol
, vol.33
, pp. 3117-3126
-
-
Rodig, N.1
Ryan, T.2
Allen, J.A.3
Pang, H.4
Grabie, N.5
-
19
-
-
0242303572
-
Regulation of PD-1, PD-L1, and PD-L2 expression during normal and autoimmune responses
-
Liang SC, Latchman YE, Buhlmann JE, Tomczak MF, Horwitz BH, et al. (2003) Regulation of PD-1, PD-L1, and PD-L2 expression during normal and autoimmune responses. Eur J Immunol 33: 2706-2716.
-
(2003)
Eur J Immunol
, vol.33
, pp. 2706-2716
-
-
Liang, S.C.1
Latchman, Y.E.2
Buhlmann, J.E.3
Tomczak, M.F.4
Horwitz, B.H.5
-
20
-
-
0037477604
-
Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis
-
Salama AD, Chitnis T, Imitola J, Ansari MJ, Akiba H, et al. (2003) Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis. J Exp Med 198: 71-78.
-
(2003)
J Exp Med
, vol.198
, pp. 71-78
-
-
Salama, A.D.1
Chitnis, T.2
Imitola, J.3
Ansari, M.J.4
Akiba, H.5
-
21
-
-
49649111913
-
B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage: Implications for the lesion pathogenesis of multiple sclerosis
-
Ortler S, Leder C, Mittelbronn M, Zozulya AL, Knolle PA, et al. (2008) B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage: implications for the lesion pathogenesis of multiple sclerosis. Eur J Immunol 38: 1734-1744.
-
(2008)
Eur J Immunol
, vol.38
, pp. 1734-1744
-
-
Ortler, S.1
Leder, C.2
Mittelbronn, M.3
Zozulya, A.L.4
Knolle, P.A.5
-
22
-
-
58149216713
-
PD-1 ligands expressed on myeloid-derived APC in the CNS regulate T-cell responses in EAE
-
Schreiner B, Bailey SL, Shin T, Chen L, Miller SD (2008) PD-1 ligands expressed on myeloid-derived APC in the CNS regulate T-cell responses in EAE. Eur J Immunol 38: 2706-2717.
-
(2008)
Eur J Immunol
, vol.38
, pp. 2706-2717
-
-
Schreiner, B.1
Bailey, S.L.2
Shin, T.3
Chen, L.4
Miller, S.D.5
-
23
-
-
33644847590
-
Differential role of programmed death-ligand 1 and programmed death-ligand 2 in regulating the susceptibility and chronic progression of experimental autoimmune encephalomyelitis
-
Zhu B, Guleria I, Khosroshahi A, Chitnis T, Imitola J, et al. (2006) Differential role of programmed death-ligand 1 and programmed death-ligand 2 in regulating the susceptibility and chronic progression of experimental autoimmune encephalomyelitis. J Immunol 176: 3480-3489.
-
(2006)
J Immunol
, vol.176
, pp. 3480-3489
-
-
Zhu, B.1
Guleria, I.2
Khosroshahi, A.3
Chitnis, T.4
Imitola, J.5
-
24
-
-
58149189061
-
Cutting edge: Programmed death-1/programmed death ligand 1 interaction regulates the induction and maintenance of invariant NKT cell anergy
-
Chang WS, Kim JY, Kim YJ, Kim YS, Lee JM, et al. (2008) Cutting edge: Programmed death-1/programmed death ligand 1 interaction regulates the induction and maintenance of invariant NKT cell anergy. J Immunol 181: 6707-6710.
-
(2008)
J Immunol
, vol.181
, pp. 6707-6710
-
-
Chang, W.S.1
Kim, J.Y.2
Kim, Y.J.3
Kim, Y.S.4
Lee, J.M.5
-
25
-
-
64849116017
-
PD-1/PD-L blockade prevents anergy induction and enhances the anti-tumor activities of glycolipid-activated invariant NKT cells
-
Parekh VV, Lalani S, Kim S, Halder R, Azuma M, et al. (2009) PD-1/PD-L blockade prevents anergy induction and enhances the anti-tumor activities of glycolipid-activated invariant NKT cells. J Immunol 182: 2816-2826.
-
(2009)
J Immunol
, vol.182
, pp. 2816-2826
-
-
Parekh, V.V.1
Lalani, S.2
Kim, S.3
Halder, R.4
Azuma, M.5
-
26
-
-
0029112507
-
CD1- restricted CD4+ T cells in major histocompatibility complex class II-deficient mice
-
Cardell S, Tangri S, Chan S, Kronenberg M, Benoist C, et al. (1995) CD1- restricted CD4+ T cells in major histocompatibility complex class II-deficient mice. J Exp Med 182: 993-1004.
-
(1995)
J Exp Med
, vol.182
, pp. 993-1004
-
-
Cardell, S.1
Tangri, S.2
Chan, S.3
Kronenberg, M.4
Benoist, C.5
-
27
-
-
0032931927
-
Diverse TCRs recognize murine CD1
-
Behar SM, Podrebarac TA, Roy CJ, Wang CR, Brenner MB (1999) Diverse TCRs recognize murine CD1. J Immunol 162: 161-167.
-
(1999)
J Immunol
, vol.162
, pp. 161-167
-
-
Behar, S.M.1
Podrebarac, T.A.2
Roy, C.J.3
Wang, C.R.4
Brenner, M.B.5
-
28
-
-
0030962696
-
CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4
-
Mendiratta SK, Martin WD, Hong S, Boesteanu A, Joyce S, et al. (1997) CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4. Immunity 6: 469-477.
-
(1997)
Immunity
, vol.6
, pp. 469-477
-
-
Mendiratta, S.K.1
Martin, W.D.2
Hong, S.3
Boesteanu, A.4
Joyce, S.5
-
29
-
-
1542511203
-
NKT cells: What's in a name?
-
Godfrey DI, MacDonald HR, Kronenberg M, Smyth MJ, Van Kaer L (2004) NKT cells: what's in a name? Nat Rev Immunol 4: 231-237.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 231-237
-
-
Godfrey, D.I.1
Macdonald, H.R.2
Kronenberg, M.3
Smyth, M.J.4
van Kaer, L.5
-
30
-
-
58149400142
-
Intracerebral dendritic cells critically modulate encephalitogenic versus regulatory immune responses in the CNS
-
Zozulya AL, Ortler S, Lee J, Weidenfeller C, Sandor M, et al. (2009) Intracerebral dendritic cells critically modulate encephalitogenic versus regulatory immune responses in the CNS. J Neurosci 29: 140-152.
-
(2009)
J Neurosci
, vol.29
, pp. 140-152
-
-
Zozulya, A.L.1
Ortler, S.2
Lee, J.3
Weidenfeller, C.4
Sandor, M.5
-
31
-
-
0032546352
-
Dendritic cells and the control of immunity
-
Banchereau J, Steinman RM (1998) Dendritic cells and the control of immunity. Nature 392: 245-252.
-
(1998)
Nature
, vol.392
, pp. 245-252
-
-
Banchereau, J.1
Steinman, R.M.2
-
32
-
-
0343953023
-
CD1d-specific NK1.1+ T cells with a transgenic variant TCR
-
Skold M, Faizunnessa NN, Wang CR, Cardell S (2000) CD1d-specific NK1.1+ T cells with a transgenic variant TCR. J Immunol 165: 168-174.
-
(2000)
J Immunol
, vol.165
, pp. 168-174
-
-
Skold, M.1
Faizunnessa, N.N.2
Wang, C.R.3
Cardell, S.4
-
33
-
-
2942683192
-
Antigeninduced tolerance by intrathymic modulation of self-recognizing inhibitory receptors
-
Hayakawa Y, Berzins SP, Crowe NY, Godfrey DI, Smyth MJ (2004) Antigeninduced tolerance by intrathymic modulation of self-recognizing inhibitory receptors. Nat Immunol 5: 590-596.
-
(2004)
Nat Immunol
, vol.5
, pp. 590-596
-
-
Hayakawa, Y.1
Berzins, S.P.2
Crowe, N.Y.3
Godfrey, D.I.4
Smyth, M.J.5
-
34
-
-
1842682026
-
Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide
-
Jahng A, Maricic I, Aguilera C, Cardell S, Halder RC, et al. (2004) Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide. J Exp Med 199: 947-957.
-
(2004)
J Exp Med
, vol.199
, pp. 947-957
-
-
Jahng, A.1
Maricic, I.2
Aguilera, C.3
Cardell, S.4
Halder, R.C.5
-
35
-
-
36049022618
-
Crossregulation between type I and type II NKT cells in regulating tumor immunity: A new immunoregulatory axis
-
Ambrosino E, Terabe M, Halder RC, Peng J, Takaku S, et al. (2007) Crossregulation between type I and type II NKT cells in regulating tumor immunity: a new immunoregulatory axis. J Immunol 179: 5126-5136.
-
(2007)
J Immunol
, vol.179
, pp. 5126-5136
-
-
Ambrosino, E.1
Terabe, M.2
Halder, R.C.3
Peng, J.4
Takaku, S.5
-
36
-
-
34547681974
-
Type II NKT cell-mediated anergy induction in type I NKT cells prevents inflammatory liver disease
-
Halder RC, Aguilera C, Maricic I, Kumar V (2007) Type II NKT cell-mediated anergy induction in type I NKT cells prevents inflammatory liver disease. J Clin Invest 117: 2302-2312.
-
(2007)
J Clin Invest
, vol.117
, pp. 2302-2312
-
-
Halder, R.C.1
Aguilera, C.2
Maricic, I.3
Kumar, V.4
-
37
-
-
58149268419
-
Cross-regulation between distinct natural killer T cell subsets influences immune response to self and foreign antigens
-
Arrenberg P, Halder R, Kumar V (2009) Cross-regulation between distinct natural killer T cell subsets influences immune response to self and foreign antigens. J Cell Physiol 218: 246-250.
-
(2009)
J Cell Physiol
, vol.218
, pp. 246-250
-
-
Arrenberg, P.1
Halder, R.2
Kumar, V.3
-
38
-
-
0037816187
-
Mouse V alpha 14i natural killer T cells are resistant to cytokine polarization in vivo
-
Matsuda JL, Gapin L, Baron JL, Sidobre S, Stetson DB, et al. (2003) Mouse V alpha 14i natural killer T cells are resistant to cytokine polarization in vivo. Proc Natl Acad Sci U S A 100: 8395-8400.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 8395-8400
-
-
Matsuda, J.L.1
Gapin, L.2
Baron, J.L.3
Sidobre, S.4
Stetson, D.B.5
-
40
-
-
0036201875
-
CD1d on antigen-transporting APC and splenic marginal zone B cells promotes NKT cell-dependent tolerance
-
Sonoda KH, Stein-Streilein J (2002) CD1d on antigen-transporting APC and splenic marginal zone B cells promotes NKT cell-dependent tolerance. Eur J Immunol 32: 848-857.
-
(2002)
Eur J Immunol
, vol.32
, pp. 848-857
-
-
Sonoda, K.H.1
Stein-Streilein, J.2
-
41
-
-
0033526066
-
The natural killer T (NKT) cell ligand alpha-galactosylceramide demonstrates its immunopotentiating effect by inducing interleukin (IL)-12 production by dendritic cells and IL-12 receptor expression on NKT cells
-
Kitamura H, Iwakabe K, Yahata T, Nishimura S, Ohta A, et al. (1999) The natural killer T (NKT) cell ligand alpha-galactosylceramide demonstrates its immunopotentiating effect by inducing interleukin (IL)-12 production by dendritic cells and IL-12 receptor expression on NKT cells. J Exp Med 189: 1121-1128.
-
(1999)
J Exp Med
, vol.189
, pp. 1121-1128
-
-
Kitamura, H.1
Iwakabe, K.2
Yahata, T.3
Nishimura, S.4
Ohta, A.5
-
42
-
-
0037787982
-
Activation of natural killer T cells by alpha-galactosylceramide rapidly induces the full maturation of dendritic cells in vivo and thereby acts as an adjuvant for combined CD4 and CD8 T cell immunity to a coadministered protein
-
Fujii S, Shimizu K, Smith C, Bonifaz L, Steinman RM (2003) Activation of natural killer T cells by alpha-galactosylceramide rapidly induces the full maturation of dendritic cells in vivo and thereby acts as an adjuvant for combined CD4 and CD8 T cell immunity to a coadministered protein. J Exp Med 198: 267-279.
-
(2003)
J Exp Med
, vol.198
, pp. 267-279
-
-
Fujii, S.1
Shimizu, K.2
Smith, C.3
Bonifaz, L.4
Steinman, R.M.5
-
43
-
-
0033012030
-
An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow
-
Lutz MB, Kukutsch N, Ogilvie AL, Rossner S, Koch F, et al. (1999) An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J Immunol Methods 223: 77-92.
-
(1999)
J Immunol Methods
, vol.223
, pp. 77-92
-
-
Lutz, M.B.1
Kukutsch, N.2
Ogilvie, A.L.3
Rossner, S.4
Koch, F.5
-
44
-
-
0033919418
-
Differences in the ligand specificity between CD1d-restricted T cells with limited and diverse T-cell receptor repertoire
-
Makowska A, Kawano T, Taniguchi M, Cardell S (2000) Differences in the ligand specificity between CD1d-restricted T cells with limited and diverse T-cell receptor repertoire. Scand J Immunol 52: 71-79.
-
(2000)
Scand J Immunol
, vol.52
, pp. 71-79
-
-
Makowska, A.1
Kawano, T.2
Taniguchi, M.3
Cardell, S.4
-
45
-
-
33744943790
-
The complementarity determining region 2 of BV8S2 (V beta 8.2) contributes to antigen recognition by rat invariant NKT cell TCR
-
Pyz E, Naidenko O, Miyake S, Yamamura T, Berberich I, et al. (2006) The complementarity determining region 2 of BV8S2 (V beta 8.2) contributes to antigen recognition by rat invariant NKT cell TCR. J Immunol 176: 7447-7455.
-
(2006)
J Immunol
, vol.176
, pp. 7447-7455
-
-
Pyz, E.1
Naidenko, O.2
Miyake, S.3
Yamamura, T.4
Berberich, I.5
|