CD1d on antigen-transporting APC and splenic marginal zone B cells promotes NKT cell-dependent tolerance

European Journal of Immunology

Volumn 32, Issue 3, 2002, Pages 848-857

  Sonoda, Koh Hei ^a,c   Stein Streilein, Joan ^a,b  

^a SCHEPENS EYE RESEARCH INSTITUTE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

CD1d; Innate immunity; MHC class I like molecule; NKT cell; Peripheral tolerance

Indexed keywords

CD1 ANTIGEN; TRANSFORMING GROWTH FACTOR BETA2;

ANIMAL CELL; ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE; CELL ACTIVATION; CONTROLLED STUDY; FEMALE; IMMUNOLOGICAL TOLERANCE; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE SUBPOPULATION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PERITONEAL EXUDATE CELL; PRIORITY JOURNAL; SPLEEN;

ADOPTIVE TRANSFER; ANIMALS; ANTIGEN-PRESENTING CELLS; ANTIGENS, CD1; ASCITIC FLUID; B-LYMPHOCYTE SUBSETS; CELLS, CULTURED; CHIMERA; CROSSES, GENETIC; EYE; FEMALE; HYPERSENSITIVITY, DELAYED; IMMUNE TOLERANCE; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; SPLEEN; TRANSFORMING GROWTH FACTOR BETA;

EID: 0036201875     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200203)32:3<848::AID-IMMU848>3.0.CO;2-I     Document Type: Article

References (45)

1. The CD1 family: A third lineage of antigen-presenting molecules
2. The CD1 system: Antigen-presenting molecules for T cell recognition of lipids and glycolipids
3. + NK T cells associated with disease development in autoimmune-prone mice
4. +-like thymocytes in the NOD mouse
5. - T cell deficiency and IDDM in NOD/Lt mice
6. NK T cell-induced protection against diabetes in Valpha14-Jalpha281 transgenic nonobese diabetic mice is associated with a Th2 shift circumscribed regionally to the islets and functionally to islet autoantigen
7. Mouse CD1-specific NK1 T cells: Development, specificity, and function
8. CD1 reactive NKT cells are required for development of systemic tolerance through an immune privileged site
9. Immunization with alpha-galactosylceramide polarizes CD1-reactive NK T cells towards Th2 cytokine synthesis
10. - (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10
11. NKT cell-derived IL-10 is essential for the differentiation of antigen-specific T regulatory cells in systemic tolerance
12. + T cells reciprocally regulate acute graft versus host disease
13. Blood-borne signals that induce anterior chamber-associated immune deviation after intracameral injection of antigen
14. CD1 expression defines subsets of follicular and marginal zone B cells in the spleen: β2-microglobulin-dependent and independent forms
15. Induction of anterior chamber-associated immune deviation requires an intact, functional spleen
16. Macrophages capable of inducing anterior chamber associated immune deviation demonstrate spleen-seeking migratory properties
17. Immuno-suppressive properties of tissues obtained from eyes with experimentally manipulated corneas
18. Aqueous humor contains transforming growth factor-beta and a small (less than 3500 daltons) inhibitor of thymocyte proliferation
19. Identification of transforming growth factor-beta as an immunosuppressive factor in aqueous humor
20. Studies on the induction of anterior chamber-associated immune deviation (ACAID). III. Induction of ACAID depends upon intraocular transforming growth factor-beta
21. TGF-β promotes immune deviation by altering accessory signals of antigen-presenting cells
22. On the mechanisms by which transforming growth factor-β2 alters antigen-presenting abilities of macrophages on T cell activation
23. Role of splenic B cells in the immune privilege of the anterior chamber of the eye
24. B cell subsets and the mature preimmune repertoire. Marginal zone and B1 B cells as part of a "natural immune memory"
25. Marginal zone B cells exhibit unique activation, proliferative and immunoglobulin secretory responses
26. Protein tyrosine phosphatase IC negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection
27. CD1, 1 expression by mouse antigen-presenting cells and marginal zone B cells
28. high B cells: A population of mixed origin
29. high lymphocytes enriched in the splenic marginal zone generate effector cells more rapidly than the bulk of follicular B cells
30. Analysis of in vivo regulatory properties of T cells activated in vitro by TGFβ2-treated antigen presenting cells
31. Splenic B cells are required for tolerogenic antigen presentation in the induction of anterior chamber-associated immune deviation (ACAID)
32. Studies on the induction of anterior chamber-associated immune deviation (ACAID). I. Evidence that an antigen-specific, ACAID-inducing, cell-associated signal exists in the peripheral blood
33. Ocular immune privilege promoted by the presentation of peptide on tolerogenic B cells in the spleen. II. Evidence for presentation by Qa-1
34. Antigen presentation in acquired immunological tolerance
35. Small B cells as antigen-presenting cells in the induction of tolerance to soluble protein antigens
36. + T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4
37. The CD1 family of lipid antigen-presenting molecules
38. - T cells
39. + T lymphocytes
40. + T cells by CD1-expressing cortical thymocytes
41. Immune deviation in relation to ocular immune privilege
42. Immune privilege as the result of local tissue barriers and immunosuppressive microenvironments
43. MIP-2 recruits NKT cells to the spleen during tolerance induction
44. Characterization of suppressor cells in anterior chamber-associated immune deviation (ACAID) induced by soluble antigen. Evidence of two functionally and phenotypically distinct T-suppressor cell populations
45. CD43 (S7) expression identifies peripheral B cell subsets