-
1
-
-
50549218525
-
The limited in vitro lifetime of human diploid cell strains
-
Hayflick L (1965) The limited in vitro lifetime of human diploid cell strains. Exp. Cell Res. 37, 614 636.
-
(1965)
Exp. Cell Res.
, vol.37
, pp. 614-636
-
-
Hayflick, L.1
-
2
-
-
34548186667
-
Cellular senescence: When bad things happen to good cells
-
Campisi J, d'Adda di Fagagna F (2007) Cellular senescence: when bad things happen to good cells. Nat. Rev. Mol. Cell Biol. 8, 729 740.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 729-740
-
-
Campisi, J.1
D'Adda Di Fagagna, F.2
-
3
-
-
0035812845
-
The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability
-
Hemann MT, Strong MA, Hao L-Y, Greider CW (2001) The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability. Cell 107, 67 77.
-
(2001)
Cell
, vol.107
, pp. 67-77
-
-
Hemann, M.T.1
Strong, M.A.2
Hao, L.-Y.3
Greider, C.W.4
-
4
-
-
2442511752
-
Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)
-
Herbig U, Jobling WA, Chen BP, Chen DJ, Sedivy JM (2004) Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a). Mol. Cell 14, 501 513.
-
(2004)
Mol. Cell
, vol.14
, pp. 501-513
-
-
Herbig, U.1
Jobling, W.A.2
Chen, B.P.3
Chen, D.J.4
Sedivy, J.M.5
-
5
-
-
0034630432
-
Accumulation of short telomeres in human fibroblasts prior to replicative senescence
-
Martens UM, Chavez EA, Poon SS, Schmoor C, Lansdorp PM (2000) Accumulation of short telomeres in human fibroblasts prior to replicative senescence. Exp. Cell Res. 256, 291 299.
-
(2000)
Exp. Cell Res.
, vol.256
, pp. 291-299
-
-
Martens, U.M.1
Chavez, E.A.2
Poon, S.S.3
Schmoor, C.4
Lansdorp, P.M.5
-
6
-
-
0027970713
-
DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts
-
Di Leonardo A, Linke SP, Clarkin K, Wahl GM (1994) DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts. Genes Dev. 8, 2540 2551.
-
(1994)
Genes Dev.
, vol.8
, pp. 2540-2551
-
-
Di Leonardo, A.1
Linke, S.P.2
Clarkin, K.3
Wahl, G.M.4
-
7
-
-
0035325264
-
Uncoupling the senescent phenotype from telomere shortening in hydrogen peroxide-treated fibroblasts
-
Chen QM, Prowse KR, Tu VC, Purdom S, Linskens MH (2001) Uncoupling the senescent phenotype from telomere shortening in hydrogen peroxide-treated fibroblasts. Exp. Cell Res. 265, 294 303.
-
(2001)
Exp. Cell Res.
, vol.265
, pp. 294-303
-
-
Chen, Q.M.1
Prowse, K.R.2
Tu, V.C.3
Purdom, S.4
Linskens, M.H.5
-
8
-
-
0042195820
-
Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts
-
Parrinello S, Samper E, Krtolica A, Goldstein J, Melov S, Campisi J (2003) Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts. Nat. Cell Biol. 5, 741 747.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 741-747
-
-
Parrinello, S.1
Samper, E.2
Krtolica, A.3
Goldstein, J.4
Melov, S.5
Campisi, J.6
-
9
-
-
0029778901
-
Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent
-
Ogryzko VV, Hirai TH, Russanova VR, Barbie DA, Howard BH (1996) Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent. Mol. Cell. Biol. 16, 5210 5218.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 5210-5218
-
-
Ogryzko, V.V.1
Hirai, T.H.2
Russanova, V.R.3
Barbie, D.A.4
Howard, B.H.5
-
10
-
-
1842861744
-
Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock
-
Munro J, Barr NI, Ireland H, Morrison V, Parkinson EK (2004) Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock. Exp. Cell Res. 295, 525 538.
-
(2004)
Exp. Cell Res.
, vol.295
, pp. 525-538
-
-
Munro, J.1
Barr, N.I.2
Ireland, H.3
Morrison, V.4
Parkinson, E.K.5
-
11
-
-
0344441890
-
A DNA damage checkpoint response in telomere-initiated senescence
-
d'Adda di Fagagna F, Reaper PM, Clay-Farrace L, Fiegler H, Carr P, Von Zglinicki T et al. (2003) A DNA damage checkpoint response in telomere-initiated senescence. Nature 426, 194 198.
-
(2003)
Nature
, vol.426
, pp. 194-198
-
-
D'Adda Di Fagagna, F.1
Reaper, P.M.2
Clay-Farrace, L.3
Fiegler, H.4
Carr, P.5
Von Zglinicki, T.6
-
12
-
-
0035449355
-
Cell cycle checkpoint signaling through the ATM and ATR kinases
-
Abraham RT (2001) Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev. 15, 2177 2196.
-
(2001)
Genes Dev.
, vol.15
, pp. 2177-2196
-
-
Abraham, R.T.1
-
13
-
-
0038418869
-
Chk1 and Chk2 kinases in checkpoint control and cancer
-
Bartek J, Lukas J (2003) Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer Cell 3, 421 429.
-
(2003)
Cancer Cell
, vol.3
, pp. 421-429
-
-
Bartek, J.1
Lukas, J.2
-
14
-
-
0033555260
-
A role for ATR in the DNA damage-induced phosphorylation of p53
-
Tibbetts RS, Brumbaugh KM, Williams JM, Sarkaria JN, Cliby WA, Shieh S-Y et al. (1999) A role for ATR in the DNA damage-induced phosphorylation of p53. Genes Dev. 13, 152 157.
-
(1999)
Genes Dev.
, vol.13
, pp. 152-157
-
-
Tibbetts, R.S.1
Brumbaugh, K.M.2
Williams, J.M.3
Sarkaria, J.N.4
Cliby, W.A.5
Shieh, S.-Y.6
-
15
-
-
0034142034
-
The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites
-
Shieh S-Y, Ahn J, Tamai K, Taya Y, Prives C (2000) The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes Dev. 14, 289 300.
-
(2000)
Genes Dev.
, vol.14
, pp. 289-300
-
-
Shieh, S.-Y.1
Ahn, J.2
Tamai, K.3
Taya, Y.4
Prives, C.5
-
16
-
-
0034142325
-
Chk2/hCds1 functions as a DNA damage checkpoint in G1 by stabilizing p53
-
Chehab NH, Malikzay A, Appel M, Halazonetis TD (2000) Chk2/hCds1 functions as a DNA damage checkpoint in G1 by stabilizing p53. Genes Dev. 14, 278 288.
-
(2000)
Genes Dev.
, vol.14
, pp. 278-288
-
-
Chehab, N.H.1
Malikzay, A.2
Appel, M.3
Halazonetis, T.D.4
-
17
-
-
0030609861
-
Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts
-
Brown JP, Wei W, Sedivy JM (1997) Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts. Science 277, 831 834.
-
(1997)
Science
, vol.277
, pp. 831-834
-
-
Brown, J.P.1
Wei, W.2
Sedivy, J.M.3
-
18
-
-
0342614209
-
Unified nomenclature for the winged helix/forkhead transcription factors
-
Kaestner KH, Knochel W, Martinez DE (2000) Unified nomenclature for the winged helix/forkhead transcription factors. Genes Dev. 14, 142 146.
-
(2000)
Genes Dev.
, vol.14
, pp. 142-146
-
-
Kaestner, K.H.1
Knochel, W.2
Martinez, D.E.3
-
19
-
-
0027270989
-
Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5
-
Clark KL, Halay ED, Lai E, Burley SK (1993) Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5. Nature 364, 412 420.
-
(1993)
Nature
, vol.364
, pp. 412-420
-
-
Clark, K.L.1
Halay, E.D.2
Lai, E.3
Burley, S.K.4
-
20
-
-
0345017786
-
Transcription factors in liver development, differentiation, and regeneration
-
Costa RH, Kalinichenko VV, Holterman AX, Wang X (2003) Transcription factors in liver development, differentiation, and regeneration. Hepatology 38, 1331 1347.
-
(2003)
Hepatology
, vol.38
, pp. 1331-1347
-
-
Costa, R.H.1
Kalinichenko, V.V.2
Holterman, A.X.3
Wang, X.4
-
21
-
-
0031020158
-
Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues
-
Ye H, Kelly TF, Samadani U, Lim L, Rubio S, Overdier DG et al. (1997) Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues. Mol. Cell. Biol. 17, 1626 1641.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 1626-1641
-
-
Ye, H.1
Kelly, T.F.2
Samadani, U.3
Lim, L.4
Rubio, S.5
Overdier, D.G.6
-
22
-
-
13944274222
-
FoxM1 is required for execution of the mitotic programme and chromosome stability
-
Laoukili J, Kooistra MR, Bras A, Kauw J, Kerkhoven RM, Morrison A et al. (2005) FoxM1 is required for execution of the mitotic programme and chromosome stability. Nat. Cell Biol. 7, 126 136.
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 126-136
-
-
Laoukili, J.1
Kooistra, M.R.2
Bras, A.3
Kauw, J.4
Kerkhoven, R.M.5
Morrison, A.6
-
23
-
-
0037168526
-
The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration
-
Wang X, Kiyokawa H, Dennewitz MB, Costa RH (2002) The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration. Proc. Natl. Acad. Sci. USA 99, 16881 16886.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 16881-16886
-
-
Wang, X.1
Kiyokawa, H.2
Dennewitz, M.B.3
Costa, R.H.4
-
24
-
-
28544449224
-
Forkhead Box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase
-
Wang I-C, Chen Y-J, Hughes D, Petrovic V, Major ML, Park HJ et al. (2005) Forkhead Box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase. Mol. Cell. Biol. 25, 10875 10894.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 10875-10894
-
-
Wang, I.-C.1
Chen, Y.-J.2
Hughes, D.3
Petrovic, V.4
Major, M.L.5
Park, H.J.6
-
25
-
-
0033506486
-
Premature expression of the winged helix transcription factor HFH-11B in regenerating mouse liver accelerates hepatocyte entry into S-phase
-
Ye H, Holterman A, Yoo KW, Franks RR, Costa RH (1999) Premature expression of the winged helix transcription factor HFH-11B in regenerating mouse liver accelerates hepatocyte entry into S-phase. Mol. Cell. Biol. 19, 8570 8580.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 8570-8580
-
-
Ye, H.1
Holterman, A.2
Yoo, K.W.3
Franks, R.R.4
Costa, R.H.5
-
26
-
-
7544231164
-
The mouse Forkhead Box m1 transcription factor is essential for hepatoblast mitosis and development of intrahepatic bile ducts and vessels during liver morphogenesis
-
Krupczak-Hollis K, Wang X, Kalinichenko VV, Gusarova GA, Wang I-C, Dennewitz MB et al. (2004) The mouse Forkhead Box m1 transcription factor is essential for hepatoblast mitosis and development of intrahepatic bile ducts and vessels during liver morphogenesis. Dev. Biol. 276, 74 88.
-
(2004)
Dev. Biol.
, vol.276
, pp. 74-88
-
-
Krupczak-Hollis, K.1
Wang, X.2
Kalinichenko, V.V.3
Gusarova, G.A.4
Wang, I.-C.5
Dennewitz, M.B.6
-
27
-
-
0037113939
-
Increased hepatic Forkhead Box M1B (FoxM1B) levels in old-aged mice stimulated liver regeneration through diminished p27Kip1 protein levels and increased Cdc25B expression
-
Wang X, Krupczak-Hollis K, Tan Y, Dennewitz MB, Adami GR, Costa RH (2002) Increased hepatic Forkhead Box M1B (FoxM1B) levels in old-aged mice stimulated liver regeneration through diminished p27Kip1 protein levels and increased Cdc25B expression. J. Biol. Chem. 277, 44310 44316.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 44310-44316
-
-
Wang, X.1
Krupczak-Hollis, K.2
Tan, Y.3
Dennewitz, M.B.4
Adami, G.R.5
Costa, R.H.6
-
28
-
-
1642382817
-
Forkhead Box M1B transcriptional activity requires binding of Cdk-cyclin complexes for phosphorylation-dependent recruitment of p300/CBP coactivators
-
Major ML, Lepe R, Costa RH (2004) Forkhead Box M1B transcriptional activity requires binding of Cdk-cyclin complexes for phosphorylation-dependent recruitment of p300/CBP coactivators. Mol. Cell. Biol. 24, 2649 2661.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 2649-2661
-
-
Major, M.L.1
Lepe, R.2
Costa, R.H.3
-
29
-
-
0033176887
-
SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27
-
Carrano AC, Eytan E, Hershko A, Pagano M (1999) SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27. Nat. Cell Biol. 1, 193 199.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 193-199
-
-
Carrano, A.C.1
Eytan, E.2
Hershko, A.3
Pagano, M.4
-
30
-
-
0033135878
-
Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation
-
Montagnoli A, Fiore F, Eytan E, Carrano AC, Draetta GF, Hershko A et al. (1999) Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation. Genes Dev. 13, 1181 1189.
-
(1999)
Genes Dev.
, vol.13
, pp. 1181-1189
-
-
Montagnoli, A.1
Fiore, F.2
Eytan, E.3
Carrano, A.C.4
Draetta, G.F.5
Hershko, A.6
-
31
-
-
0035092687
-
The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27
-
Ganoth D, Bornstein G, Ko TK, Larsen B, Tyers M, Pagano M et al. (2001) The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27. Nat. Cell Biol. 3, 321 324.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 321-324
-
-
Ganoth, D.1
Bornstein, G.2
Ko, T.K.3
Larsen, B.4
Tyers, M.5
Pagano, M.6
-
32
-
-
50249083985
-
Anaphase-promoting complex/cyclosome-Cdh1-mediated proteolysis of the Forkhead Box M1 transcription factor is critical for regulated entry into S phase
-
Park HJ, Costa RH, Lau LF, Tyner AL, Raychaudhuri P (2008) Anaphase-promoting complex/cyclosome-Cdh1-mediated proteolysis of the Forkhead Box M1 transcription factor is critical for regulated entry into S phase. Mol. Cell. Biol. 28, 5162 5171.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 5162-5171
-
-
Park, H.J.1
Costa, R.H.2
Lau, L.F.3
Tyner, A.L.4
Raychaudhuri, P.5
-
33
-
-
33846619711
-
Chk2 mediates stabilization of the FoxM1 transcription factor to stimulate expression of DNA repair genes
-
Tan Y, Raychaudhuri P, Costa RH (2007) Chk2 mediates stabilization of the FoxM1 transcription factor to stimulate expression of DNA repair genes. Mol. Cell. Biol. 27, 1007 1016.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 1007-1016
-
-
Tan, Y.1
Raychaudhuri, P.2
Costa, R.H.3
-
34
-
-
0034656991
-
Domain specific interaction in the XRCC1-DNA polymerase beta complex
-
Marintchev A, Robertson A, Dimitriadis EK, Prasad R, Wilson SH, Mullen GP (2000) Domain specific interaction in the XRCC1-DNA polymerase beta complex. Nucleic Acids Res. 28, 2049 2059.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 2049-2059
-
-
Marintchev, A.1
Robertson, A.2
Dimitriadis, E.K.3
Prasad, R.4
Wilson, S.H.5
Mullen, G.P.6
-
35
-
-
0033179235
-
BRCA2 is required for ionizing radiation-induced assembly of Rad51 complex in vivo
-
Yuan SS, Lee SY, Chen G, Song M, Tomlinson GE, Lee EY (1999) BRCA2 is required for ionizing radiation-induced assembly of Rad51 complex in vivo. Cancer Res. 59, 3547 3551.
-
(1999)
Cancer Res.
, vol.59
, pp. 3547-3551
-
-
Yuan, S.S.1
Lee, S.Y.2
Chen, G.3
Song, M.4
Tomlinson, G.E.5
Lee, E.Y.6
-
36
-
-
0035801472
-
Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences
-
Tutt A, Bertwistle D, Valentine J, Gabriel A, Swift S, Ross G et al. (2001) Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences. EMBO J. 20, 4704 4716.
-
(2001)
EMBO J.
, vol.20
, pp. 4704-4716
-
-
Tutt, A.1
Bertwistle, D.2
Valentine, J.3
Gabriel, A.4
Swift, S.5
Ross, G.6
-
37
-
-
64249172774
-
Inhibition of matrix metalloproteinase-2 enhances radiosensitivity by abrogating radiation-induced FoxM1-mediated G2/M arrest in A549 lung cancer cells
-
Chetty C, Bhoopathi P, Rao JS, Lakka SS (2009) Inhibition of matrix metalloproteinase-2 enhances radiosensitivity by abrogating radiation-induced FoxM1-mediated G2/M arrest in A549 lung cancer cells. Int. J. Cancer 124, 2468 2477.
-
(2009)
Int. J. Cancer
, vol.124
, pp. 2468-2477
-
-
Chetty, C.1
Bhoopathi, P.2
Rao, J.S.3
Lakka, S.S.4
-
38
-
-
0141733085
-
Ubiquitous expression of the Forkhead Box M1B transgene accelerates proliferation of distinct pulmonary cell types following lung injury
-
Kalinichenko VV, Gusarova GA, Tan Y, Wang I-C, Major ML, Wang X et al. (2003) Ubiquitous expression of the Forkhead Box M1B transgene accelerates proliferation of distinct pulmonary cell types following lung injury. J. Biol. Chem. 278, 37888 37894.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 37888-37894
-
-
Kalinichenko, V.V.1
Gusarova, G.A.2
Tan, Y.3
Wang, I.-C.4
Major, M.L.5
Wang, X.6
-
40
-
-
0030612349
-
Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging
-
Zindy F, Quelle DE, Roussel MF, Sherr CJ (1997) Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging. Oncogene 15, 203 211.
-
(1997)
Oncogene
, vol.15
, pp. 203-211
-
-
Zindy, F.1
Quelle, D.E.2
Roussel, M.F.3
Sherr, C.J.4
-
41
-
-
0034980666
-
Induction of senescence by oncogenic Ras
-
Palmero I, Serrano M (2001) Induction of senescence by oncogenic Ras. Methods Enzymol. 333, 247 256.
-
(2001)
Methods Enzymol.
, vol.333
, pp. 247-256
-
-
Palmero, I.1
Serrano, M.2
-
42
-
-
0033572894
-
Differentiation between senescence (M1) and crisis (M2) in human fibroblast cultures
-
Wei W, Sedivy JM (1999) Differentiation between senescence (M1) and crisis (M2) in human fibroblast cultures. Exp. Cell Res. 253, 519 522.
-
(1999)
Exp. Cell Res.
, vol.253
, pp. 519-522
-
-
Wei, W.1
Sedivy, J.M.2
-
43
-
-
0035949627
-
Increased levels of Forkhead Box M1B transcription factor in transgenic mouse hepatocytes prevents age-related proliferation defects in regenerating liver
-
Wang X, Quail E, Hung N-J, Tan Y, Ye H, Costa RH (2001) Increased levels of Forkhead Box M1B transcription factor in transgenic mouse hepatocytes prevents age-related proliferation defects in regenerating liver. Proc. Natl. Acad. Sci. USA 98, 11468 11473.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 11468-11473
-
-
Wang, X.1
Quail, E.2
Hung, N.-J.3
Tan, Y.4
Ye, H.5
Costa, R.H.6
-
44
-
-
33645991514
-
Increased expression of hepatocyte nuclear factor 6 stimulates hepatocyte proliferation during mouse liver regeneration
-
Tan Y, Yoshida Y, Hughes DE, Costa RH (2006) Increased expression of hepatocyte nuclear factor 6 stimulates hepatocyte proliferation during mouse liver regeneration. Gastroenterology 130, 1283 1300.
-
(2006)
Gastroenterology
, vol.130
, pp. 1283-1300
-
-
Tan, Y.1
Yoshida, Y.2
Hughes, D.E.3
Costa, R.H.4
-
45
-
-
0036210624
-
Maintaining HNF-6 expression prevents AdHNF3b mediated decrease in hepatic levels of Glut2 and glycogen
-
Tan Y, Adami G, Costa RH (2002) Maintaining HNF-6 expression prevents AdHNF3b mediated decrease in hepatic levels of Glut2 and glycogen. Hepatology 35, 790 798.
-
(2002)
Hepatology
, vol.35
, pp. 790-798
-
-
Tan, Y.1
Adami, G.2
Costa, R.H.3
-
46
-
-
47749108741
-
FoxM1c counteracts oxidative stress-induced senescence and stimulates Bmi-1 expression
-
Li SKM, Smith DK, Leung WY, Cheung AMS, Lam EWF, Dimri GP et al. (2008) FoxM1c counteracts oxidative stress-induced senescence and stimulates Bmi-1 expression. J. Biol. Chem. 283, 16545 16553.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 16545-16553
-
-
Li, S.K.M.1
Smith, D.K.2
Leung, W.Y.3
Cheung, A.M.S.4
Lam, E.W.F.5
Dimri, G.P.6
-
47
-
-
0033214946
-
Ubiquitous expression of marker transgenes in mice and rats
-
Kisseberth WC, Brettingen NT, Lohse JK, Sandgren EP (1999) Ubiquitous expression of marker transgenes in mice and rats. Dev. Biol. 214, 128 138.
-
(1999)
Dev. Biol.
, vol.214
, pp. 128-138
-
-
Kisseberth, W.C.1
Brettingen, N.T.2
Lohse, J.K.3
Sandgren, E.P.4
-
48
-
-
85069245205
-
Transgenic expression of the forkhead box M1 transcription factor induces formation of lung tumors
-
Wang IC, Meliton L, Tretiakova M, Costa RH, Kalinichenko VV, Kalin TV (2008) Transgenic expression of the forkhead box M1 transcription factor induces formation of lung tumors. Oncogene 17, 17.
-
(2008)
Oncogene
, vol.17
, pp. 17
-
-
Wang, I.C.1
Meliton, L.2
Tretiakova, M.3
Costa, R.H.4
Kalinichenko, V.V.5
Kalin, T.V.6
-
49
-
-
2942570699
-
Oxygen accelerates the accumulation of mutations during the senescence and immortalization of murine cells in culture
-
Busuttil RA, Rubio M, Dolle ME, Campisi J, Vijg J (2003) Oxygen accelerates the accumulation of mutations during the senescence and immortalization of murine cells in culture. Aging Cell 2, 287 294.
-
(2003)
Aging Cell
, vol.2
, pp. 287-294
-
-
Busuttil, R.A.1
Rubio, M.2
Dolle, M.E.3
Campisi, J.4
Vijg, J.5
-
50
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C et al. (1995) A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc. Natl. Acad. Sci. USA 92, 9363 9367.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
Lee, X.2
Basile, G.3
Acosta, M.4
Scott, G.5
Roskelley, C.6
-
51
-
-
0030667702
-
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
-
Shieh S-Y, Ikeda M, Taya Y, Prives C (1997) DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 91, 325 334.
-
(1997)
Cell
, vol.91
, pp. 325-334
-
-
Shieh, S.-Y.1
Ikeda, M.2
Taya, Y.3
Prives, C.4
-
52
-
-
11144353897
-
Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor
-
Kalinichenko VV, Major ML, Wang X, Petrovic V, Kuechle J, Yoder HM et al. (2004) Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor. Genes Dev. 18, 830 850.
-
(2004)
Genes Dev.
, vol.18
, pp. 830-850
-
-
Kalinichenko, V.V.1
Major, M.L.2
Wang, X.3
Petrovic, V.4
Kuechle, J.5
Yoder, H.M.6
-
53
-
-
0035478788
-
Integrating stress-response and cell-cycle checkpoint pathways
-
Pearce AK, Humphrey TC (2001) Integrating stress-response and cell-cycle checkpoint pathways. Trends Cell Biol. 11, 426 433.
-
(2001)
Trends Cell Biol.
, vol.11
, pp. 426-433
-
-
Pearce, A.K.1
Humphrey, T.C.2
-
54
-
-
0030867582
-
Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25
-
Sanchez Y, Wong C, Thoma RS, Richman R, Wu Z, Piwnica-Worms H et al. (1997) Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25. Science 277, 1497 1501.
-
(1997)
Science
, vol.277
, pp. 1497-1501
-
-
Sanchez, Y.1
Wong, C.2
Thoma, R.S.3
Richman, R.4
Wu, Z.5
Piwnica-Worms, H.6
-
55
-
-
32944459113
-
Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY Transgenic Mice
-
Kalin TV, Wang I-C, Ackerson TJ, Major ML, Detrisac CJ, Kalinichenko VV et al. (2006) Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY Transgenic Mice. Cancer Res. 66, 1712 1720.
-
(2006)
Cancer Res.
, vol.66
, pp. 1712-1720
-
-
Kalin, T.V.1
Wang, I.-C.2
Ackerson, T.J.3
Major, M.L.4
Detrisac, C.J.5
Kalinichenko, V.V.6
-
56
-
-
33644542405
-
The Forkhead Box m1 Transcription Factor Stimulates the Proliferation of Tumor Cells during Development of Lung Cancer
-
Kim I-M, Ackerson T, Ramakrishna S, Tretiakova M, Wang I-C, Kalin TV et al. (2006) The Forkhead Box m1 Transcription Factor Stimulates the Proliferation of Tumor Cells during Development of Lung Cancer. Cancer Res. 66, 2153 2161.
-
(2006)
Cancer Res.
, vol.66
, pp. 2153-2161
-
-
Kim, I.-M.1
Ackerson, T.2
Ramakrishna, S.3
Tretiakova, M.4
Wang, I.-C.5
Kalin, T.V.6
-
57
-
-
65949124894
-
Critical role and regulation of transcription factor FoxM1 in human gastric cancer angiogenesis and progression
-
Li Q, Zhang N, Jia Z, Le X, Dai B, Wei D et al. (2009) Critical role and regulation of transcription factor FoxM1 in human gastric cancer angiogenesis and progression. Cancer Res. 69, 3501 3509.
-
(2009)
Cancer Res.
, vol.69
, pp. 3501-3509
-
-
Li, Q.1
Zhang, N.2
Jia, Z.3
Le, X.4
Dai, B.5
Wei, D.6
-
58
-
-
44149090307
-
Chk1 suppresses a caspase-2 apoptotic response to DNA damage that bypasses p53, Bcl-2, and caspase-3
-
Sidi S, Sanda T, Kennedy RD, Hagen AT, Jette CA, Hoffmans R et al. (2008) Chk1 suppresses a caspase-2 apoptotic response to DNA damage that bypasses p53, Bcl-2, and caspase-3. Cell 133, 864 877.
-
(2008)
Cell
, vol.133
, pp. 864-877
-
-
Sidi, S.1
Sanda, T.2
Kennedy, R.D.3
Hagen, A.T.4
Jette, C.A.5
Hoffmans, R.6
-
59
-
-
58949092221
-
ATR and Chk1 suppress a caspase-3-dependent apoptotic response following DNA replication stress
-
Myers K, Gagou ME, Zuazua-Villar P, Rodriguez R, Meuth M (2009) ATR and Chk1 suppress a caspase-3-dependent apoptotic response following DNA replication stress. PLoS Genet. 5, e1000324.
-
(2009)
PLoS Genet.
, vol.5
, pp. 1000324
-
-
Myers, K.1
Gagou, M.E.2
Zuazua-Villar, P.3
Rodriguez, R.4
Meuth, M.5
-
60
-
-
0034737456
-
Mitotic misregulation and human aging
-
Ly DH, Lockhart DJ, Lerner RA, Schultz PG (2000) Mitotic misregulation and human aging. Science 287, 2486 2492.
-
(2000)
Science
, vol.287
, pp. 2486-2492
-
-
Ly, D.H.1
Lockhart, D.J.2
Lerner, R.A.3
Schultz, P.G.4
|