Inhibition of matrix metalloproteinase-2 enhances radiosensitivity by abrogating radiation-induced FoxM1-mediated G2/M arrest in A549 lung cancer cells

International Journal of Cancer

Volumn 124, Issue 10, 2009, Pages 2468-2477

  Chetty, Chandramu ^a   Bhoopathi, Praveen ^a   Rao, Jasti S ^a   Lakka, Sajani S ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

A549; Foxm1; G2 m arrest; MMP 2; Radiosensitization

Indexed keywords

ADENOVIRUS VECTOR; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; GELATINASE A; MESSENGER RNA; PROTEIN P21; PROTEIN P53; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXM1; UNCLASSIFIED DRUG; XRCC1 PROTEIN; FORKHEAD TRANSCRIPTION FACTOR; FOXM1 PROTEIN, HUMAN; PRIMER DNA; PROTEIN SERINE THREONINE KINASE; PROTEINASE INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL DESTRUCTION; CANCER RADIOTHERAPY; CANCER TISSUE; CARCINOMA CELL; CELL ASSAY; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CLONOGENIC ASSAY; CONTROLLED STUDY; DNA REPAIR; ENZYME ACTIVITY; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENE TARGETING; HISTOLOGY; HUMAN; HUMAN CELL; IN VIVO STUDY; LUNG ADENOCARCINOMA; LUNG NON SMALL CELL CANCER; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; PROTEINASE INHIBITION; RADIATION RESPONSE; RADIOSENSITIVITY; RNA INTERFERENCE; VIRAL GENE DELIVERY SYSTEM; CELL DIVISION; DNA DAMAGE; DRUG ANTAGONISM; ENZYMOLOGY; LUNG TUMOR; NUCLEOTIDE SEQUENCE; PATHOLOGY; PHYSIOLOGY; RADIATION DOSE; RADIATION EXPOSURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE;

APOPTOSIS; BASE SEQUENCE; CELL DIVISION; CELL LINE, TUMOR; DNA DAMAGE; DNA PRIMERS; DNA REPAIR; FORKHEAD TRANSCRIPTION FACTORS; G2 PHASE; HUMANS; IN SITU NICK-END LABELING; LUNG NEOPLASMS; MATRIX METALLOPROTEINASE 2; PROTEASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; RADIATION TOLERANCE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 64249172774     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.24209     Document Type: Article

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