Is the reactivity of M(II)-arene complexes of 3-hydroxy-2(1 H)-pyridones to biomolecules the anticancer activity determining parameteŕ

Inorganic Chemistry

Volumn 49, Issue 17, 2010, Pages 7953-7963

  Hanif, Muhammad ^a   Henke, Helena ^a   Meier, Samuel M ^a   Martic, Sanela ^b   Labib, Mahmoud ^b   Kandioller, Wolfgang ^a   Jakupec, Michael A ^a   Arion, Vladimir B ^a   Kraatz, Heinz Bernhard ^b   Keppler, Bernhard K ^a   Hartinger, Christian G ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYPYRIDINE; 2-HYDROXYPYRIDINE; AMINO ACID; ANTINEOPLASTIC AGENT; CYCLIN DEPENDENT KINASE 2; CYTOCHROME C; DNA; OSMIUM DERIVATIVE; PYRIDONE DERIVATIVE; RUTHENIUM DERIVATIVE; UBIQUITIN;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG SCREENING; HUMAN; METABOLISM; NEOPLASM; SYNTHESIS; TUMOR CELL LINE; X RAY CRYSTALLOGRAPHY;

AMINO ACIDS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CRYSTALLOGRAPHY, X-RAY; CYCLIN-DEPENDENT KINASE 2; CYTOCHROMES C; DNA; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MODELS, MOLECULAR; NEOPLASMS; OSMIUM COMPOUNDS; PYRIDONES; RUTHENIUM COMPOUNDS; UBIQUITIN;

EID: 77956224504     PISSN: 00201669     EISSN: None     Source Type: Journal    
DOI: 10.1021/ic1009785     Document Type: Article

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