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Volumn 18, Issue 1, 2008, Pages 405-408
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Syntheses and in vitro evaluation of arylsulfone-based MMP inhibitors with heterocycle-derived zinc-binding groups (ZBGs)
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Author keywords
Arylsulfone; Matrix metalloproteinase inhibitor; MMP 2; MMP 9; Zinc binding group
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Indexed keywords
COLLAGENASE 3;
GELATINASE A;
GELATINASE B;
HETEROCYCLIC COMPOUND;
INTERSTITIAL COLLAGENASE;
MATRIX METALLOPROTEINASE INHIBITOR;
POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE;
SULFONE DERIVATIVE;
ZINC;
ARTICLE;
DRUG POTENCY;
DRUG SCREENING;
DRUG SELECTIVITY;
DRUG SYNTHESIS;
ENZYME INHIBITION;
HYDROGEN BOND;
IC 50;
IN VITRO STUDY;
STRUCTURE ACTIVITY RELATION;
HETEROCYCLIC COMPOUNDS;
LACTAMS;
MATRIX METALLOPROTEINASE 2;
MATRIX METALLOPROTEINASE 9;
PROTEASE INHIBITORS;
PYRIDONES;
STRUCTURE-ACTIVITY RELATIONSHIP;
SULFONES;
ZINC;
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EID: 37549036309
PISSN: 0960894X
EISSN: None
Source Type: Journal
DOI: 10.1016/j.bmcl.2007.10.049 Document Type: Article |
Times cited : (42)
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References (14)
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