Use of chelating ligands to tune the reactive site of half-sandwich ruthenium(II)-arene anticancer complexes

Chemistry - A European Journal

Volumn 10, Issue 20, 2004, Pages 5173-5179

  Fernández, Rafael ^a   Melchart, Michael ^a   Habtemariam, Abraha ^a   Parsons, Simon ^a   Sadler, Peter J ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Antitumor agents; Arene ligands; Bioinorganic chemistry; Nucleobases; Ruthenium

Indexed keywords

CHELATION; HYDROGEN BONDS; PROTEINS; TUMORS;

ADENINE; CHELATING LIGANDS; NUCLEOBASES; SELECTIVITY;

RUTHENIUM COMPOUNDS;

ANTINEOPLASTIC AGENT; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; RUTHENIUM COMPLEX;

ARTICLE; BINDING AFFINITY; CHELATION; ENZYME SPECIFICITY; HYDROGEN BOND; HYDROLYSIS;

ANTINEOPLASTIC AGENTS; BINDING SITES; CHELATING AGENTS; CRYSTALLOGRAPHY, X-RAY; HYDROGEN BONDING; HYDROGEN-ION CONCENTRATION; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; RUTHENIUM; RUTHENIUM COMPOUNDS;

EID: 7244244207     PISSN: 09476539     EISSN: None     Source Type: Journal    
DOI: 10.1002/chem.200400640     Document Type: Article

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