Influence of heparin mimetics on assembly of the FGF·FGFR4 signaling complex

Journal of Biological Chemistry

Volumn 285, Issue 34, 2010, Pages 26628-26640

  Saxena, Krishna ^a   Schieborr, Ulrich ^a   Anderka, Oliver ^a   Duchardt Ferner, Elke ^a   Elshorst, Bettina ^a   Gande, Santosh Lakshmi ^a   Janzon, Julia ^a   Kudlinzki, Denis ^a   Sreeramulu, Sridhar ^a   Dreyer, Matthias K ^b   Wendt, K Ulrich ^b   Herbert, Corentin ^c   Duchaussoy, Philippe ^c   Bianciotto, Marc ^c   Driguez, Pierre Alexandre ^c   Lassalle, Gilbert ^c   Savi, Pierre ^c   Mohammadi, Moosa ^d   Bono, Françoise ^c   Schwalbe, Harald ^a  

^a GOETHE UNIVERSITY   (Germany)

^b SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

^c SANOFI   (France)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINARY INTERACTIONS; BINDING INTERACTION; BIOLOGICAL ASSAYS; COOPERATIVITY; DIFFERENTIAL ACTIVITY; FGF RECEPTORS; FIBROBLAST GROWTH FACTOR; GLYCOSAMINOGLYCANS; HEPARAN SULFATES; HEXASACCHARIDES; INTERACTION SITE; ISOTHERMAL TITRATION CALORIMETRY; MIMETICS; MOLECULAR BASIS; NMR SPECTROSCOPY; OCTASACCHARIDE; ORGANIC SYNTHESIS; SIGNALING COMPLEX; SYMMETRIC MODE;

BINDING ENERGY; CELL CULTURE; DIMERIZATION; MAMMALS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYSACCHARIDES; SIZE EXCLUSION CHROMATOGRAPHY;

SIGNALING;

DECASACCHARIDE; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 4; HEPARIN DERIVATIVE; HEXASACCHARIDE; IMMUNOGLOBULIN; IMMUNOGLOBULIN D2; OLIGOSACCHARIDE; PROTEOHEPARAN SULFATE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; BIOASSAY; COMPLEX FORMATION; CONTROLLED STUDY; DIMERIZATION; GEL PERMEATION CHROMATOGRAPHY; HUMAN; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR MECHANICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; SIGNAL TRANSDUCTION;

ANIMALS; BINDING SITES; CELL LINE; FIBROBLAST GROWTH FACTORS; HEPARIN; HUMANS; MICE; MULTIPROTEIN COMPLEXES; OLIGOSACCHARIDES; PROTEIN BINDING; PROTEIN MULTIMERIZATION; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 4; STRUCTURE-ACTIVITY RELATIONSHIP;

MAMMALIA;

EID: 77956208869     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.095109     Document Type: Article

References (78)

1. Ornitz, D. M., and Itoh, N. (2001) Genome Biol. 2, REVIEWS3005
2. Popovici, C., Roubin, R., Coulier, F., and Birnbaum, D. (2005) Bioessays 27, 849-857
3. Eswarakumar, V. P., Lax, I., and Schlessinger, J. (2005) Cytokine Growth Factor Rev. 16, 139-149
4. Beenken, A., and Mohammadi, M. (2009) Nat. Rev. Drug Discovery 8, 235-253
5. Ornitz, D. M. (2005) Cytokine Growth Factor Rev. 16, 205-213
6. Martin, G. (2001) Bioessays 23, 865-868
7. Kuro-o, M. (2008) Trends Endocrinol. Metab. 19, 239-245
8. Mohammadi, M., Olsen, S. K., and Ibrahimi, O. A. (2005) Cytokine Growth Factor Rev. 16, 107-137
9. Johnson, D. E., and Williams, L. T. (1993) Adv. Cancer Res. 60, 1-41
10. Zhu, X., Hsu, B. T., and Rees, D. C. (1993) Structure 1, 27-34
11. Eriksson, A. E., Cousens, L. S., Weaver, L. H., and Matthews, B. W. (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 3441-3445
12. Bellosta, P., Iwahori, A., Plotnikov, A. N., Eliseenkova, A. V., Basilico, C., and Mohammadi, M. (2001) Mol. Cell. Biol. 21, 5946-5957
13. Osslund, T. D., Syed, R., Singer, E., Hsu, E. W., Nybo, R., Chen, B. L., Harvey, T., Arakawa, T., Narhi, L. O., Chirino, A., and Morris, C. F. (1998) Protein Sci. 7, 1681-1690
14. Olsen, S. K., Li, J. Y., Bromleigh, C., Eliseenkova, A. V., Ibrahimi, O. A., Lao, Z., Zhang, F., Linhardt, R. J., Joyner, A. L., and Mohammadi, M. (2006) Genes Dev. 20, 185-198
15. Plotnikov, A. N., Eliseenkova, A. V., Ibrahimi, O. A., Shriver, Z., Sasisekharan, R., Lemmon, M. A., and Mohammadi, M. (2001) J. Biol. Chem. 276, 4322-4329
16. Yeh, B. K., Igarashi, M., Eliseenkova, A. V., Plotnikov, A. N., Sher, I., Ron, D., Aaronson, S. A., and Mohammadi, M. (2003) Proc. Natl. Acad. Sci. U.S.A. 100, 2266-2271
17. Harmer, N. J., Pellegrini, L., Chirgadze, D., Fernandez-Recio, J., and Blundell, T. L. (2004) Biochemistry 43, 629-640
18. Kalinina, J., Byron, S. A., Makarenkova, H. P., Olsen, S. K., Eliseenkova, A. V., Larochelle, W. J., Dhanabal, M., Blais, S., Ornitz, D. M., Day, L. A., Neubert, T. A., Pollock, P. M., and Mohammadi, M. (2009) Mol. Cell. Biol. 29, 4663-4678
19. Goetz, R., Beenken, A., Ibrahimi, O. A., Kalinina, J., Olsen, S. K., Eliseenkova, A. V., Xu, C., Neubert, T. A., Zhang, F., Linhardt, R. J., Yu, X., White, K. E., Inagaki, T., Kliewer, S. A., Yamamoto, M., Kurosu, H., Ogawa, Y., Kuro-o, M., Lanske, B., Razzaque, M. S., and Mohammadi, M. (2007) Mol. Cell. Biol. 27, 3417-3428
20. Ori, A., Wilkinson, M. C., and Fernig, D. G. (2008) Front. Biosci. 13, 4309-4338
21. Faham, S., Hileman, R. E., Fromm, J. R., Linhardt, R. J., and Rees, D. C. (1996) Science 271, 1116-1120
22. DiGabriele, A. D., Lax, I., Chen, D. I., Svahn, C. M., Jaye, M., Schlessinger, J., and Hendrickson, W. A. (1998) Nature 393, 812-817
23. Schlessinger, J., Plotnikov, A. N., Ibrahimi, O. A., Eliseenkova, A. V., Yeh, B. K., Yayon, A., Linhardt, R. J., and Mohammadi, M. (2000) Mol. Cell. 6, 743-750
24. Pellegrini, L., Burke, D. F., von Delft, F., Mulloy, B., and Blundell, T. L. (2000) Nature 407, 1029-1034
25. Ornitz, D. M., Herr, A. B., Nilsson, M., Westman, J., Svahn, C. M., and Waksman, G. (1995) Science 268, 432-436
26. Olsen, S. K., Garbi, M., Zampieri, N., Eliseenkova, A. V., Ornitz, D. M., Goldfarb, M., and Mohammadi, M. (2003) J. Biol. Chem. 278, 34226-34236
27. Goetz, R., Dover, K., Laezza, F., Shtraizent, N., Huang, X., Tchetchik, D., Eliseenkova, A. V., Xu, C. F., Neubert, T. A., Ornitz, D. M., Goldfarb, M., and Mohammadi, M. (2009) J. Biol. Chem. 284, 17883-17896
28. Goldfarb, M. (2005) Cytokine Growth Factor Rev. 16, 215-220
29. Plotnikov, A. N., Hubbard, S. R., Schlessinger, J., and Mohammadi, M. (2000) Cell 101, 413-424
30. Kan, M., Wang, F., Xu, J., Crabb, J. W., Hou, J., and McKeehan, W. L. (1993) Science 259, 1918-1921
31. Olsen, S. K., Ibrahimi, O. A., Raucci, A., Zhang, F., Eliseenkova, A. V., Yayon, A., Basilico, C., Linhardt, R. J., Schlessinger, J., and Mohammadi, M. (2004) Proc. Natl. Acad. Sci. U.S.A. 101, 935-940
32. Kiselyov, V. V., Kochoyan, A., Poulsen, F. M., Bock, E., and Berezin, V. (2006) Protein Sci. 15, 2318-2322
33. Wang, F., Kan, M., Yan, G., Xu, J., and McKeehan, W. L. (1995) J. Biol. Chem. 270, 10231-10235
34. Shimizu, A., Tada, K., Shukunami, C., Hiraki, Y., Kurokawa, T., Magane, N., and Kurokawa-Seo, M. (2001) J. Biol. Chem. 276, 11031-11040
35. Miki, T., Fleming, T. P., Bottaro, D. P., Rubin, J. S., Ron, D., and Aaronson, S. A. (1991) Science 251, 72-75
36. Yayon, A., Zimmer, Y., Shen, G. H., Avivi, A., Yarden, Y., and Givol, D. (1992) EMBO J. 11, 1885-1890
37. Goldstrohm, A. C., Greenleaf, A. L., and Garcia-Blanco, M. A. (2001) Gene 277, 31-47
38. Beer, H. D., Vindevoghel, L., Gait, M. J., Revest, J. M., Duan, D. R., Mason, I., Dickson, C., and Werner, S. (2000) J. Biol. Chem. 275, 16091-16097
39. Orr-Urtreger, A., Bedford, M. T., Burakova, T., Arman, E., Zimmer, Y., Yayon, A., Givol, D., and Lonai, P. (1993) Dev. Biol. 158, 475-486
40. Wuechner, C., Nordqvist, A. C., Winterpacht, A., Zabel, B., and Schalling, M. (1996) Int. J. Dev. Biol. 40, 1185-1188
41. Scotet, E., and Houssaint, E. (1995) Biochim. Biophys. Acta 1264, 238-242
42. Zhang, X., Ibrahimi, O. A., Olsen, S. K., Umemori, H., Mohammadi, M., and Ornitz, D. M. (2006) J. Biol. Chem. 281, 15694-15700
43. Ornitz, D. M., Xu, J., Colvin, J. S., McEwen, D. G., MacArthur, C. A., Coulier, F., Gao, G., and Goldfarb, M. (1996) J. Biol. Chem. 271, 15292-15297
44. Ibrahimi, O. A., Zhang, F., Eliseenkova, A. V., Linhardt, R. J., and Mohammadi, M. (2004) Hum. Mol. Genet. 13, 69-78
45. Lin, X., Buff, E. M., Perrimon, N., and Michelson, A. M. (1999) Development 126, 3715-3723
46. Inatani, M., Irie, F., Plump, A. S., Tessier-Lavigne, M., and Yamaguchi, Y. (2003) Science 302, 1044-1046
47. Rapraeger, A. C., Krufka, A., and Olwin, B. B. (1991) Science 252, 1705-1708
48. Makarenkova, H. P., Hoffman, M. P., Beenken, A., Eliseenkova, A. V., Meech, R., Tsau, C., Patel, V. N., Lang, R. A., and Mohammadi, M. (2009) Sci. Signal. 2, ra55
49. Flaumenhaft, R., Moscatelli, D., and Rifkin, D. B. (1990) J. Cell Biol. 111, 1651-1659
50. Sommer, A., and Rifkin, D. B. (1989) J. Cell Physiol. 138, 215-220
51. Volkin, D. B., Tsai, P. K., Dabora, J. M., Gress, J. O., Burke, C. J., Linhardt, R. J., and Middaugh, C. R. (1993) Arch. Biochem. Biophys. 300, 30-41
52. Mohammadi, M., Olsen, S. K., and Goetz, R. (2005) Curr. Opin. Struct. Biol. 15, 506-516
53. Goodger, S. J., Robinson, C. J., Murphy, K. J., Gasiunas, N., Harmer, N. J., Blundell, T. L., Pye, D. A., and Gallagher, J. T. (2008) J. Biol. Chem. 283, 13001-13008
54. Ibrahimi, O. A., Yeh, B. K., Eliseenkova, A. V., Zhang, F., Olsen, S. K., Igarashi, M., Aaronson, S. A., Linhardt, R. J., and Mohammadi, M. (2005) Mol. Cell. Biol. 25, 671-684
55. Wu, Z. L., Lech, M., Beeler, D. L., and Rosenberg, R. D. (2004) J. Biol. Chem. 279, 1861-1866
56. Delehedde, M., Lyon, M., Gallagher, J. T., Rudland, P. S., and Fernig, D. G. (2002) Biochem. J. 366, 235-244
57. Ostrovsky, O., Berman, B., Gallagher, J., Mulloy, B., Fernig, D. G., Delehedde, M., and Ron, D. (2002) J. Biol. Chem. 277, 2444-2453
58. Ogura, K., Nagata, K., Hatanaka, H., Habuchi, H., Kimata, K., Tate, S., Ravera, M. W., Jaye, M., Schlessinger, J., and Inagaki, F. (1999) J. Biomol. NMR 13, 11-24
59. Moy, F. J., Seddon, A. P., Campbell, E. B., Böhlen, P., and Powers, R. (1995) J. Biomol. NMR 6, 245-254
60. Hung, K. W., Kumar, T. K., Kathir, K. M., Xu, P., Ni, F., Ji, H. H., Chen, M. C., Yang, C. C., Lin, F. P., Chiu, I. M., and Yu, C. (2005) Biochemistry 44, 15787-15798
61. Ryu, E. K., Cho, K. J., Kim, J. K., Harmer, N. J., Blundell, T. L., and Kim, K. H. (2006) Protein Expr. Purif. 49, 15-22
62. Anderka, O., Boyken, J., Aschenbach, U., Batzer, A., Boscheinen, O., and Schmoll, D. (2008) J. Biol. Chem. 283, 31333-31340
63. Tabeur, C., Mallet, J. M., Bono, F., Herbert, J. M., Petitou, M., and Sinaÿ, P. (1999) Bioorg. Med. Chem. 7, 2003-2012
64. Kiselyov, V. V., Bock, E., Berezin, V., and Poulsen, F. M. (2006) Protein Sci. 15, 1512-1515
65. Kochoyan, A., Poulsen, F. M., Berezin, V., Bock, E., and Kiselyov, V. V. (2008) FEBS Lett. 582, 3374-3378
66. Ornitz, D. M., Yayon, A., Flanagan, J. G., Svahn, C. M., Levi, E., and Leder, P. (1992) Mol. Cell. Biol. 12, 240-247
67. Spivak-Kroizman, T., Lemmon, M. A., Dikic, I., Ladbury, J. E., Pinchasi, D., Huang, J., Jaye, M., Crumley, G., Schlessinger, J., and Lax, I. (1994) Cell 79, 1015-1024
68. Robinson, C. J., Harmer, N. J., Goodger, S. J., Blundell, T. L., and Gallagher, J. T. (2005) J. Biol. Chem. 280, 42274-42282
69. Gao, G., and Goldfarb, M. (1995) EMBO J. 14, 2183-2190
70. Loo, B. M., Kreuger, J., Jalkanen, M., Lindahl, U., and Salmivirta, M. (2001) J. Biol. Chem. 276, 16868-16876
71. Jastrebova, N., Vanwildemeersch, M., Rapraeger, A. C., Giménez-Gallego, G., Lindahl, U., and Spillmann, D. (2006) J. Biol. Chem. 281, 26884-26892
72. Ibrahimi, O. A., Zhang, F., Hrstka, S. C., Mohammadi, M., and Linhardt, R. J. (2004) Biochemistry 43, 4724-4730
73. Canales, A., Angulo, J., Ojeda, R., Bruix, M., Fayos, R., Lozano, R., Giménez-Gallego, G., Martín-Lomas, M., Nieto, P. M., and Jiménez-Barbero, J. (2005) J. Am. Chem. Soc. 127, 5778-5779
74. Sasisekharan, R., Raman, R., and Prabhakar, V. (2006) Annu. Rev. Biomed. Eng. 8, 181-231
75. de Paz, J. L., Noti, C., Böhm, F., Werner, S., and Seeberger, P. H. (2007) Chem. Biol. 14, 879-887
76. Griffith, B. R., Allen, B. L., Rapraeger, A. C., and Kiessling, L. L. (2004) J. Am. Chem. Soc. 126, 1608-1609
77. Kwan, C. P., Venkataraman, G., Shriver, Z., Raman, R., Liu, D., Qi, Y., Varticovski, L., and Sasisekharan, R. (2001) J. Biol. Chem. 276, 23421-23429
78. Wu, Z. L., and Lech, M. (2005) J. Biol. Chem. 280, 33749-33755