Biophysical characterization of the interaction between hepatic glucokinase and its regulatory protein: Impact of physiological and pharmacological effectors

Journal of Biological Chemistry

Volumn 283, Issue 46, 2008, Pages 31333-31340

  Anderka, Oliver ^a   Boyken, Janina ^a,b   Aschenbach, Ursula ^a   Batzer, Andreas ^a   Boscheinen, Oliver ^a   Schmoll, Dieter ^a  

^a SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

^b UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDES; AMINES; BINDING ENERGY; BIOCHEMISTRY; ENZYME ACTIVITY; ENZYMES; FLOW INTERACTIONS; GLUCOSE; HYDROPHOBICITY; LIVER; PHYSIOLOGICAL MODELS; SURFACE PLASMON RESONANCE; VOLUMETRIC ANALYSIS;

ANTIDIABETIC; BINDING AFFINITIES; BIOPHYSICAL CHARACTERIZATIONS; COMPLEX FORMATIONS; DRIVING FORCES; GLUCOKINASE; GLUCOSE METABOLISMS; HEAT CAPACITIES; HYDROPHOBIC INTERACTIONS; INHIBITORY COMPLEXES; IONIC CONTRIBUTIONS; ISOTHERMAL TITRATION CALORIMETRIES; KEY ENZYMES; PROTEIN INTERACTIONS; REGULATORY PROTEINS; SMALL MOLECULES; SURFACE PLASMONS; TYPE 2 DIABETES;

PH EFFECTS;

ADENOSINE TRIPHOSPHATE; BUFFER; FRUCTOSE 6 PHOSPHATE; GLUCOKINASE; GLUCOKINASE REGULATORY PROTEIN; GLUCOSE; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONTROLLED STUDY; DISSOCIATION; ENTHALPY; ENTROPY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BINDING; ENZYME REGULATION; HUMAN; HYDROPHOBICITY; ION TRANSPORT; ISOTHERMAL TITRATION CALORIMETRY; LIVER; MOLECULAR MECHANICS; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTON TRANSPORT; RAT; SURFACE PLASMON RESONANCE; THERMODYNAMICS;

ANIMALS; BIOPHYSICS; BUFFERS; CARRIER PROTEINS; GLUCOKINASE; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; LIVER; PROTEIN BINDING; RATS; RECOMBINANT PROTEINS; SURFACE PLASMON RESONANCE; TEMPERATURE; THERMODYNAMICS;

EID: 57649133952     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M805434200     Document Type: Article

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