Correlation between the 1.6 Å crystal structure and mutational analysis of keratinocyte growth factor

Protein Science

Volumn 7, Issue 8, 1998, Pages 1681-1690

  Osslund, Timothy D ^a   Syed, Rashid ^a   Singer, Elizabeth ^a   Hsu, Eric W J ^a   Nybo, Rebecca ^a   Chen, Bao Lu ^b   Harvey, Timothy ^a   Arakawa, Tsutomu ^a   Narhi, Linda Owers ^a   Chirino, Arthur ^a   Morris, Charles F ^a  

^a AMGEN INC   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Amino acid sequence; Binding sites; Chemistry (ch); Comparative study; Crystallography X ray; Fibroblast growth factor.kgf.fgf10; Human; Molecular sequence data; Protein conformation; Protein folding

Indexed keywords

FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR; HEPARIN; KERATINOCYTE GROWTH FACTOR;

AMINO ACID ANALYSIS; AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; HUMAN; HYDROGEN BOND; MITOGENESIS; MOLECULAR GENETICS; MUTAGENESIS; MUTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE; RECEPTOR BINDING; STRUCTURE ANALYSIS; THERMOSTABILITY; X RAY CRYSTALLOGRAPHY;

EID: 0032464009     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1002/pro.5560070803     Document Type: Article

References (5)

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2. Baird A, Schubert D, Ling N, Guillemin R. 1988. Receptor- and heparin-binding domains of basic fibroblast growth factor. Proc Natl Acad Sci USA 55:2324-2328.
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4. Bonneh-Barkay D, Shlissel M, Berman B, Shaoul E, Admon A, Vlodavsky I, Carey DJ, Asundi VK, Reich-Slotky R, Ron D. 1997. Identification of glypican as a dual modulator of the biological activity of fibroblast growth factors. J Biol Chem 272:12415-12421.
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