Interrogation of noncovalent complexes by ESI-MS: A powerful platform for high throughput drug Discovery

Mass Spectrometry in Medicinal Chemistry

Volumn 36, Issue , 2007, Pages 321-338

  Hofstadler, Steven A ^a   Sannes Lowery, Kristin A ^a  

^a ISIS PHARMACEUTICALS   (United States)

Author keywords

Analysis of noncovalent complexes by ESI MS; High throughput drug discovery; Multitarget affinity; Oligonucleotides; Proteins; Solution conditions; Specificity screening

Indexed keywords

OLIGONUCLEOTIDES; PROTEINS;

DRUG DISCOVERY; HIGH THROUGHPUT; MULTITARGET; NON-COVALENT COMPLEXES; SOLUTION CONDITIONS;

THROUGHPUT;

EID: 77956183412     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9783527610907.ch10     Document Type: Chapter

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