Activation of caspases and poly (ADP-ribose) polymerase cleavage to induce apoptosis in leukemia HL-60 cells by Inula racemosa

Toxicology in Vitro

Volumn 24, Issue 6, 2010, Pages 1599-1609

  Pal, Harish Chandra ^a   Sehar, Irum ^a   Bhushan, Shashi ^a   Gupta, Bishan Dutt ^a   Saxena, Ajit Kumar ^a  

^a CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

Author keywords

Apoptosis; Compositae; Cytotoxicity; Inula racemosa; Tumor growth inhibition

Indexed keywords

ALANTOLACTONE; ANTINEOPLASTIC AGENT; BUTANOL; CAMPTOTHECIN; CASPASE 3; CASPASE 6; CASPASE 8; CASPASE 9; CHLOROFORM; CYTOCHROME C; HEXANE; INULA RACEMOSA EXTRACT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PLANT EXTRACT; PROTEIN BAX; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR RECEPTOR 1; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL STRAIN HL 60; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG CYTOTOXICITY; DRUG STRUCTURE; HUMAN; HUMAN CELL; IC 50; INULA; INULA RACEMOSA; LEUKEMIA CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PLANT ROOT; PROTEIN CLEAVAGE; UPREGULATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASES; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA, NEOPLASM; ENZYME ACTIVATION; HL-60 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; INULA; LEUKEMIA; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; PLANT EXTRACTS; PLANT ROOTS; POLY(ADP-RIBOSE) POLYMERASES; REACTIVE OXYGEN SPECIES; TUMOR STEM CELL ASSAY;

ASTERACEAE; CITRUS MACROPHYLLA; INULA RACEMOSA;

EID: 77956172542     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2010.06.007     Document Type: Article

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