A novel lignan composition from Cedrus deodara induces apoptosis and early nitric oxide generation in human leukemia Molt-4 and HL-60 cells

Nitric Oxide - Biology and Chemistry

Volumn 14, Issue 1, 2006, Pages 72-88

  Shashi, Bhushan ^a   Jaswant, Singh ^a   Madhusudana, Rao J ^b   Kumar, Saxena A ^a   Nabi, Qazi G ^a  

^a CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

^b INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Apoptosis; Caspases; Mitochondrial membrane potential; Molt 4 and HL 60 cells; Necrosis; New lignan composition; Nitric oxide; Peroxide

Indexed keywords

AP9 CD; ASCORBIC ACID; CASPASE 3; CASPASE 8; CASPASE 9; CEDRUS DEODARA EXTRACT; CYCLOSPORIN A; DIBENZYL BUTYROLACTOL; LIGNAN DERIVATIVE; LIPOCORTIN 5; MATAIRESINOL; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PEROXIDE; PLANT EXTRACT; UNCLASSIFIED DRUG; WIKSTROMAL;

APOPTOSIS; ARTICLE; CEDRUS; CELL DEATH; CELL FRACTIONATION; CELL MEMBRANE DEPOLARIZATION; CELL MEMBRANE POTENTIAL; CELL PROLIFERATION; CELL STRAIN HL 60; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MITOCHONDRION; MITOSIS; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; CEDRUS; CELL DIVISION; CELL LINE, TUMOR; CELLS, CULTURED; FLOW CYTOMETRY; HEPATOCYTES; HUMANS; LEUKEMIA; LIGNANS; MEMBRANE POTENTIALS; NECROSIS; NITRIC OXIDE; PEROXIDES; RATS; REACTIVE OXYGEN SPECIES;

CEDRUS; CEDRUS DEODARA;

EID: 30344432119     PISSN: 10898603     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.niox.2005.09.009     Document Type: Article

References (41)

1. K.M. Debatin Activation of apoptosis pathways by anti-cancer treatment Toxicol. Lett. 112/113 2000 41 48
2. M.R. Wilson Apoptotic signal transduction: emerging pathways Biochem. Cell Biol. 76 1998 573 582
3. X.M. Sun, M. MacFarlane, J. Zhuang, B.B. Wolf, D.R. Green, and G.M. Cohen Distinct caspase cascades are initiated in receptor-mediated and chemical induced apoptosis J. Biol. Chem. 274 1999 5053 5060
4. P. Ghafourifar, U. Brimgold, S.D. Klein, and C. Richter Mitochondrial nitric oxide synthase, oxidative stress and apoptosis Biol. Signals Recept. 10 2001 57 65
5. Li Chun-Qi, and G.N. Wogan Nitric oxide as modulator of apoptosis Cancer Lett. 226 2005 1 15
6. C. Kellner, and S.J. Zunin Nitric oxide is synthesized in acute leukemia cell, after exposure to phenolic antioxidants and initially protects against mitochondrial membrane depolarization Cancer Lett. 215 2004 43 52
7. A. Szewczyk, and L. Wojtczak Mitochondria as a pharmacological target Pharmacol. Rev. 54 2002 101 127
8. G. Minotti, P. Menna, E. Salvatorelli, G. Cairo, and L. Gianni Anthacyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity Pharmacol. Rev. 56 2004 185 229
9. L. Virág, E. Szabò, P. Gergely, and C. Szabò Peroxynitrite-induced cytotoxicity: mechanism and opportunities for intervention Toxicol. Lett. 140/141 2003 113 124
10. V. Borutaite, and G.C. Brown Nitric oxide induces apoptosis via hydrogen peroxide but necrosis via energy and thiol depletion Free Radic. Biol. Med. 35 2003 1457 1468
11. J.M. Rao, P.V. Srinivas, J.S. Yadav, K.V. Raghavan, A.K. Saxena, M. Shanmugavel, H. Kampasi, G.N. Qazi, Herbal chemical composition for the treatment of cancer, United States Patent 6 (2003) 649,6.
12. A. Monks, D. Seudiero, P. Skehan, R. Shoemaker, K. Paull, D. Vistica, C. Hose, J. Langley, P. Cronise, A. Vaigro-Wolff, M. Gray-Goodrich, H. Campbell, J. Mayo, and M. Boyd Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines J. Natl. Cancer Inst. 83 1991 757 766
13. W.D. MacRae, and G.H.N. Towers Biological Activities of Lignans Phytochemistry 23 1984 1207 1220
14. M.K. Khamlach, and R. Brown DE Lignanes.16. Premieres syntheses totales du (+)- Wikstromal, de la (-)- Trachelogenine de la (-) nortrachelogenine et des lignoides apparentes Tetrahedron 48 1992 10115 10126
15. T.F. Imbert Discovery of podophyllotoxins Biochemie 80 1998 207 222
16. C. Canel, R.M. Moraes, F.E. Dayan, and D. Ferreira Molecules of interest: podophyllotoxin Phytochemistry 54 2000 115 120
17. J.D. Hainsworth, and F.A. Greco Etoposide: twenty years later Ann. Oncol. 6 1995 325 341
18. J. Heckenkamp, D. Leszczynski, J. Schiereck, J. Kung, and G.M. La Muraglia Different effects of photodynamic therapy and gamma-irradiation on vascular smooth muscle cells and matrix: implications for inhibiting restenosis Arterioscler. Thomb. Vasc. Biol. 19 1999 2154 2161
19. I. Vermes, C. Haanen, H. Steffen-Nakken, and C. Reutellingsperger A novel assay for apoptosis, Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labeled AnnexinV J. Immunol. Methods 184 1995 39 51
20. H. Kojima, K. Sakurai, K. Kikuchi, S. Kawahara, Y. Kirino, H. Nagoshi, Y. Hirata, and T. Nagano Development of a fluorescent indicator for the nitric oxide based on the fluorescein chomophore Chem. Pharm. Bull. 46 1998 373 375
21. G. Rothe, and G. Valet Flow cytometric analysis of respiratory burst activity in phagocytes with hydroethidine and 2′,7′- dichlorofluorescein J. Leuko. Biol. 47 1996 440 448
22. 2 in cultured endothelial cells Arch. Biochem. Biophys. 302 1993 348 355
23. J.J. Lemasters, and A.L. Nieminen Mitochondrial oxygen radical formation during reductive and oxidative stress to intact hepatocytes Biosci. Rep. 17 1997 281 291
24. R.K. Reen, R. Karan, K. Singh, V. Karan, R.K. Johi, and J. Singh Screening of various Swertia species extracts in primary monolayer cultures of rat hepatocytes against carbon tetrachloride- and paracetamol-induced toxicity J. Ethnopharmacol. 75 2001 239 247
25. A.H. Lowry, N.J. Rosebrough, A.L. Farr, and R.J. Randall Protein measurement with the Folin phenol reagent J. Biol. Chem. 193 1951 265 275
26. K.M. Broekemeier, M. Dempsey, and D.R. Pfeiffer Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria J. Biol. Chem. 264 1989 7826 7830
27. R. Radi, A. Cassina, R. Hodara, C. Quijano, and L. Castro Peroxynitrite reactions and formation in mitochondria Free. Radic. Biol. Med. 33 2002 1451 1464
28. P. Secchiero, A. Gonelli, C. Celeghini, P. Mirandola, L. Guidotti, L. Visani, S. Capitani, and G. Zauli Activation of the nitric oxide synthase pathway represents a key component of tumor necrosis factor-related apoptosis-inducing ligand mediated cytotoxicity on hematologic malignancies Blood 98 2001 2220 2228
29. H.M. Oh, S.C. Choi, H.S. Lee, C.H. Chun, G.S. Seo, E.Y. Choi, H.J. Lee, M.S. Lee, J.J. Yeom, S.J. Choi, W.C. Han, J.M. Oh, Y.T. Chung, J.S. Chun, K.M. Lee, and C.D. Jun Combined action of extracellular signal-regulated kinase and p38 kinase rescues Molt4 T cells from nitric oxide-induced apoptotic and necrotic cell deat Free. Radic. Biol. Med. 37 2004 463 479
30. C. Szabo, G.J. Southan, and C. Jhiemermann Beneficial affects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase Proc. Natl. Acad. Sci. USA 91 1994 12472 12476
31. M. Leist, B. Single, H. Naumann, E. Fava, B. Simon, S. Kuhnle, and P. Nicotera Inhibition of mitochondrial ATP generation by nitric oxide switches apoptosis to necrosis Exp. Cell Res. 249 1999 396 403
32. C.G. Brown, and V. Borutaite Nitric oxide inhibition of mitochondrial respiration and its role in cell death Free. Radic. Biol. Med. 33 2002 1140 1450
33. E. Simamura, K.I. Hirai, H. Shimada, J. Pan, and J. Koyam Mitochondrial damage prior to apoptosis in furanonaphthoquinone treated lung cancer Cancer Detect. Prev. 27 2003 5 13
34. A.E.O. Fisher, and D.P. Naughto Redox-active metal ions and oxidative stress: therapeutic implications Proc. Indian Natl. Sci. Acad. B 69 2003 453 460
35. L.C. Richter, and U. Vollgraf Mode of cell injury and death after hydrogen peroxide exposure in cultured oligodedendroglia cells Exp. Cell Res. 244 1998 218 229
36. D.A. Wink, and J.B. Mitchell Chemical biology of nitric oxide: insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide Free. Radic. Biol. Med. 25 1998 434 456
37. J. Yuan, G.A.C. Murrell, A. Trickett, and M.X. Wang Involvement of cytochrome c release and caspase-3 activation in the oxidative stress-induced apoptosis in human tendon fibroblasts Biochim. Et. Biophy. Acta 1641 2003 35 41
38. L.W. Oberley, and G.R. Buettner Role of superoxide dismutase in cancer, A review Cancer Res. 39 1979 1141 1149
39. N. Li, Y. Zhai, and T.D. Oberley Two distinct mechanisms for inhibition of cell growth in human prostrate carcinoma cells with antioxidant enzyme imbalance Free. Radic. Biol. Med. 26 1999 1554 1568
40. E.E. Kelley, S.M. Martin, C.J. Weydert, S.A. Walsh, L.W. Oberley, and G.R. Buettner Endogenous production of nitric oxide sensitizes breast cancer cells to photodynamic action Free. Radic. Biol. Med. 33 2002 S368
41. H.G. Keizer, H.M. Pinedo, G.J. Schuurhuis, and H. Joenje Doxorubicin (adriamycin): a critical review of free radical-dependent mechanisms of cytotoxicity Pharmacol. Ther. 47 1990 219 231