An essential oil and its major constituent isointermedeol induce apoptosis by increased expression of mitochondrial cytochrome c and apical death receptors in human leukaemia HL-60 cells

Chemico-Biological Interactions

Volumn 171, Issue 3, 2008, Pages 332-347

  Kumar, Ajay ^a   Malik, Fayaz ^a   Bhushan, Shashi ^a   Sethi, Vijay K ^a   Shahi, Ashok K ^a   kaur, Jagdeep ^b   Taneja, Subhash C ^a   Qazi, Ghulam N ^a   Singh, Jaswant ^a  

^a CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

^b PANJAB UNIVERSITY   (India)

Author keywords

Apoptosis; Cymbopogon flexuosus; Essential oil; HL 60 cells; Isointermedeol

Indexed keywords

CASPASE 8; CYMBOPOGON FLEXUOSUS EXTRACT; CYTOCHROME C; DEATH RECEPTOR; ESSENTIAL OIL; ISOINTERMEDEOL; LIPOCORTIN 5; PLANT EXTRACT; TUMOR NECROSIS FACTOR RECEPTOR 1; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL STRAIN HL 60; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; HUMAN; HUMAN CELL; PROTEIN EXPRESSION;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 8; CASPASE 9; CELL CYCLE; CELL PROLIFERATION; CYMBOPOGON; CYTOCHROMES C; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HL-60 CELLS; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; MITOCHONDRIA; MOLECULAR CONFORMATION; NF-KAPPA B; OILS, VOLATILE; REACTIVE OXYGEN SPECIES; RECEPTORS, TUMOR NECROSIS FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; SESQUITERPENES; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

CYMBOPOGON CITRATUS; CYMBOPOGON FLEXUOSUS;

EID: 38549141615     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2007.10.003     Document Type: Article

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