Cytotoxic and pro-apoptotic activities of cynaropicrin, a sesquiterpene lactone, on the viability of leukocyte cancer cell lines

European Journal of Pharmacology

Volumn 492, Issue 2-3, 2004, Pages 85-94

  Cho, Jae Youl ^a   Kim, Ae Ra ^b   Jung, Jee H ^b   Chun, Taehoon ^c   Rhee, Man Hee ^d   Yoo, Eun Sook ^e  

^a Kangwon National University   (South Korea)

^b Pusan National University   (South Korea)

^c Hanyang University   (South Korea)

^d Kyungpook National University   (South Korea)

^e Jeju National University School of Medicine   (South Korea)

Author keywords

Apoptosis; Cell cycle arrest; Cynaropicrin; Cytotoxicity; PKC ; Sesquiterpene lactone

Indexed keywords

ACETYLCYSTEINE; ANTINEOPLASTIC AGENT; CYNAROPICRIN; CYSTEINE; DNA FRAGMENT; PROTEIN KINASE C DELTA; PROTEIN KINASE C INHIBITOR; REACTIVE OXYGEN METABOLITE; ROTTLERIN; SCAVENGER; SESQUITERPENE LACTONE;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE G1 PHASE; CELL STRAIN U937; CELL STRUCTURE; CELL TYPE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG EFFECT; DRUG STRUCTURE; EOSINOPHIL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LEUKOCYTE; MACROPHAGE; MITOSIS INHIBITION; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; DNA FRAGMENTATION; FLOW CYTOMETRY; HUMANS; L-LACTATE DEHYDROGENASE; LACTONES; LEUKOCYTES; MICROSCOPY, PHASE-CONTRAST; PROTEIN KINASE C; REACTIVE OXYGEN SPECIES; SESQUITERPENES;

EID: 2642583062     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.03.027     Document Type: Article

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