A triterpenediol from Boswellia serrata induces apoptosis through both the intrinsic and extrinsic apoptotic pathways in human leukemia HL-60 cells

Apoptosis

Volumn 12, Issue 10, 2007, Pages 1911-1926

  Bhushan, Shashi ^a   Kumar, Ajay ^a   Malik, Fayaz ^a   Andotra, Samar Singh ^a   Sethi, Vijay Kumar ^a   Kaur, Indu Pal ^b   Taneja, Subhash Chandra ^a   Qazi, Ghulam Nabi ^a   Singh, Jaswant ^a  

^a CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

^b PANJAB UNIVERSITY   (India)

Author keywords

Apoptosis; Boswellia serrata; Cytochrome c; HL 60 cells; RNOS; Triterpenediol

Indexed keywords

ANNEXIN; APOPTOSIS INDUCING FACTOR; BOSWELLIA SERRATA EXTRACT; CASPASE 8; CYTOCHROME C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITRIC OXIDE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SURVIVIN; TERPENE DERIVATIVE; TRITERPENEDIOL; TUMOR NECROSIS FACTOR RECEPTOR 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CELL PROLIFERATION; CELL STRAIN HL 60; CONTROLLED STUDY; CYTOSOL; DRUG MECHANISM; DRUG SYNTHESIS; ENZYME ACTIVATION; GENE EXPRESSION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; LEUKEMIA; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; UPREGULATION;

ACETYLCYSTEINE; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BOSWELLIA; CASPASES; CELL NUCLEUS; CELL PROLIFERATION; CELLS, CULTURED; DNA FRAGMENTATION; ENZYME INHIBITORS; FREE RADICAL SCAVENGERS; HL-60 CELLS; HUMANS; ISOTHIURONIUM; MACROPHAGES, PERITONEAL; MEMBRANE POTENTIALS; MICE; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MOLECULAR STRUCTURE; NITRIC OXIDE; PLANT EXTRACTS; POLY(ADP-RIBOSE) POLYMERASES; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; TRITERPENES;

BOSWELLIA SERRATA;

EID: 34848927498     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-007-0105-5     Document Type: Article

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