메뉴 건너뛰기




Volumn 34, Issue 19, 2006, Pages 5383-5394

Systematic characterization of 2′-deoxynucleoside- 5′-triphosphate analogs as substrates for DNA polymerases by polymerase chain reaction and kinetic studies on enzymatic production of modified DNA

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; DEOXYCYTIDINE TRIPHOSPHATE; DEOXYURIDINE TRIPHOSPHATE DERIVATIVE; DNA; DNA POLYMERASE; PLASMID DNA; TAQ POLYMERASE; THYMINE;

EID: 33750993500     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkl637     Document Type: Article
Times cited : (142)

References (62)
  • 2
    • 0031151976 scopus 로고    scopus 로고
    • DNA aptamers and DNA enzymes
    • Breaker,R.R. (1997) DNA aptamers and DNA enzymes. Curr. Opin. Chem. Biol., 1, 26-31.
    • (1997) Curr. Opin. Chem. Biol. , vol.1 , pp. 26-31
    • Breaker, R.R.1
  • 3
    • 0033150946 scopus 로고    scopus 로고
    • Deoxyribozymes: New players in the ancient game of biocatalysis
    • Li,Y. and Breaker,R.R. (1999) Deoxyribozymes: New players in the ancient game of biocatalysis. Curr. Opin. Struct. Biol., 9, 315-323.
    • (1999) Curr. Opin. Struct. Biol. , vol.9 , pp. 315-323
    • Li, Y.1    Breaker, R.R.2
  • 4
    • 0033797244 scopus 로고    scopus 로고
    • Nucleic acid aptamers-from selection in vitro to applications in vivo
    • Famulok,M., Mayer,G. and Blind,M. (2000) Nucleic acid aptamers-from selection in vitro to applications in vivo. Acc. Chem. Res., 33, 591-599.
    • (2000) Acc. Chem. Res. , vol.33 , pp. 591-599
    • Famulok, M.1    Mayer, G.2    Blind, M.3
  • 5
    • 0036240768 scopus 로고    scopus 로고
    • Deoxyribozymes: New activities and new applications
    • Emilsson,G.M. and Breaker,R.R. (2002) Deoxyribozymes: New activities and new applications. Cell. Mol. Life Sci., 59, 596-607.
    • (2002) Cell. Mol. Life Sci. , vol.59 , pp. 596-607
    • Emilsson, G.M.1    Breaker, R.R.2
  • 6
    • 17144380787 scopus 로고    scopus 로고
    • Allosteric aptamers and aptazymes as probes for screening approaches
    • Famulok,M. (2005) Allosteric aptamers and aptazymes as probes for screening approaches. Curr. Opin. Mol. Ther., 7, 137-143.
    • (2005) Curr. Opin. Mol. Ther. , vol.7 , pp. 137-143
    • Famulok, M.1
  • 7
    • 0028136665 scopus 로고
    • The application of a modified nucleotide in aptamer selection: Novel thrombin aptamers containing 5-(1-pentynyl)-2′-deoxyuridine
    • Latham,J.A., Johnson,R. and Toole,J.J. (1994) The application of a modified nucleotide in aptamer selection: Novel thrombin aptamers containing 5-(1-pentynyl)-2′-deoxyuridine. Nucleic Acids Res., 22, 2817-2822.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 2817-2822
    • Latham, J.A.1    Johnson, R.2    Toole, J.J.3
  • 8
    • 0033610480 scopus 로고    scopus 로고
    • Quantitative analysis of receptors for adenosine nucleotides obtained via in vitro selection from a library incorporating a cationic nucleotide analog
    • Battersby,T.R., Ang,D.N., Burgstaller,P., Jurczyk,S.C., Bowser,M.T., Buchanan,D.D., Kennedy,R.T. and Benner,S.A. (1999) Quantitative analysis of receptors for adenosine nucleotides obtained via in vitro selection from a library incorporating a cationic nucleotide analog. J. Am. Chem. Soc., 121, 9781-9789.
    • (1999) J. Am. Chem. Soc. , vol.121 , pp. 9781-9789
    • Battersby, T.R.1    Ang, D.N.2    Burgstaller, P.3    Jurczyk, S.C.4    Bowser, M.T.5    Buchanan, D.D.6    Kennedy, R.T.7    Benner, S.A.8
  • 10
    • 0344213748 scopus 로고    scopus 로고
    • Chemically modified nucleic acid aptamers for in vitro selections: Evolving evolution
    • Kusser,W. (2000) Chemically modified nucleic acid aptamers for in vitro selections: Evolving evolution. Rev. Mol. Biotechnol., 74, 27-38.
    • (2000) Rev. Mol. Biotechnol. , vol.74 , pp. 27-38
    • Kusser, W.1
  • 11
    • 0035961485 scopus 로고    scopus 로고
    • Bridging the gap between proteins and nucleic acids: A metal-independent RNAse A mimic with two protein-like functionalities
    • Perrin,D.M., Garestier,T. and Hélène,C. (2001) Bridging the gap between proteins and nucleic acids: A metal-independent RNAse A mimic with two protein-like functionalities. J. Am. Chem. Soc., 123, 1556-1563.
    • (2001) J. Am. Chem. Soc. , vol.123 , pp. 1556-1563
    • Perrin, D.M.1    Garestier, T.2    Hélène, C.3
  • 12
    • 0037189886 scopus 로고    scopus 로고
    • Toward an RNaseA mimic: A DNAzyme with imidazoles and cationic amines
    • Lermer,L., Roupioz,Y., Ting,R. and Perrin,D.M. (2002) Toward an RNaseA mimic: A DNAzyme with imidazoles and cationic amines. J. Am. Chem. Soc., 124, 9960-9961.
    • (2002) J. Am. Chem. Soc. , vol.124 , pp. 9960-9961
    • Lermer, L.1    Roupioz, Y.2    Ting, R.3    Perrin, D.M.4
  • 13
    • 0038499722 scopus 로고    scopus 로고
    • Functional tuning of nucleic acids by chemical modifications: Tailored oligonucleotides as drugs, devices, and diagnostics
    • Verma,S., Jäger,S., Thum,O. and Famulok,M. (2003) Functional tuning of nucleic acids by chemical modifications: Tailored oligonucleotides as drugs, devices, and diagnostics. Chem. Rec., 3, 51-60.
    • (2003) Chem. Rec. , vol.3 , pp. 51-60
    • Verma, S.1    Jäger, S.2    Thum, O.3    Famulok, M.4
  • 14
    • 13544253729 scopus 로고    scopus 로고
    • Substrate specificity and kinetic framework of a DNAzyme with an expanded chemical repertoire: A putative RNaseA mimic that catalyzes RNA hydrolysis independent of a divalent metal cation
    • Ting,R., Thomas,J.M., Lermer,L. and Perrin,D.M. (2004) Substrate specificity and kinetic framework of a DNAzyme with an expanded chemical repertoire: A putative RNaseA mimic that catalyzes RNA hydrolysis independent of a divalent metal cation. Nucleic Acids Res., 32, 6660-6672.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 6660-6672
    • Ting, R.1    Thomas, J.M.2    Lermer, L.3    Perrin, D.M.4
  • 15
    • 5644237711 scopus 로고    scopus 로고
    • Triggering DNAzymes with light: A photoactive C8 thioether-linked adenosine
    • Ting,R., Lermer,L. and Perrin,D.M. (2004) Triggering DNAzymes with light: A photoactive C8 thioether-linked adenosine. J. Am. Chem. Soc., 126, 12720-12721.
    • (2004) J. Am. Chem. Soc. , vol.126 , pp. 12720-12721
    • Ting, R.1    Lermer, L.2    Perrin, D.M.3
  • 16
    • 1842607442 scopus 로고    scopus 로고
    • Covalent schiff base catalysis and turnover by a DNAzyme: A M2-independent AP-endonuclease mimic
    • May,J.P., Ting,R., Lermer,L., Thomas,J.M., Roupioz,Y. and Perrin,D.M. (2004) Covalent schiff base catalysis and turnover by a DNAzyme: A M2-independent AP-endonuclease mimic. J. Am. Chem. Soc., 126, 4145-4156.
    • (2004) J. Am. Chem. Soc. , vol.126 , pp. 4145-4156
    • May, J.P.1    Ting, R.2    Lermer, L.3    Thomas, J.M.4    Roupioz, Y.5    Perrin, D.M.6
  • 17
    • 1842618467 scopus 로고    scopus 로고
    • Sequence-specific cleavage of RNA in the absence of divalent metal ions by a DNAzyme incorporating imidazolyl and amino functionalities
    • Sidorov,A.V., Grasby,J.A. and Williams,D.M. (2004) Sequence-specific cleavage of RNA in the absence of divalent metal ions by a DNAzyme incorporating imidazolyl and amino functionalities. Nucleic Acids Res., 32, 1591-1601.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 1591-1601
    • Sidorov, A.V.1    Grasby, J.A.2    Williams, D.M.3
  • 18
    • 1342279558 scopus 로고    scopus 로고
    • Sialyllactose-binding modified DNA aptamer bearing additional functionality by SELEX
    • Masud,M.M., Kuwahara,M., Ozaki,H. and Sawai,H. (2004) Sialyllactose-binding modified DNA aptamer bearing additional functionality by SELEX. Bioorg. Med. Chem., 12, 1111-1120.
    • (2004) Bioorg. Med. Chem. , vol.12 , pp. 1111-1120
    • Masud, M.M.1    Kuwahara, M.2    Ozaki, H.3    Sawai, H.4
  • 20
    • 0030898510 scopus 로고    scopus 로고
    • A general purpose RNA-cleaving DNA enzyme
    • Santoro,S.W. and Joyce,G.F. (1997) A general purpose RNA-cleaving DNA enzyme. Proc. Natl Acad. Sci. USA, 94, 4262-4266.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 4262-4266
    • Santoro, S.W.1    Joyce, G.F.2
  • 21
    • 0000917638 scopus 로고    scopus 로고
    • In vitro selection of catalytic polynucleotides
    • Breaker,R.R. (1997) In vitro selection of catalytic polynucleotides. Chem Rev., 97, 371-390.
    • (1997) Chem Rev. , vol.97 , pp. 371-390
    • Breaker, R.R.1
  • 22
    • 0031102380 scopus 로고    scopus 로고
    • Nucleic acid selection and the challenge of combinatorial chemistry
    • Osborne,S.E. and Ellington,A.D. (1997) Nucleic acid selection and the challenge of combinatorial chemistry. Chem. Rev., 97, 349-370.
    • (1997) Chem. Rev. , vol.97 , pp. 349-370
    • Osborne, S.E.1    Ellington, A.D.2
  • 23
    • 0032853242 scopus 로고    scopus 로고
    • In vitro selection of functional nucleic acids
    • Wilson,D.S. and Szostak,J.W. (1999) In vitro selection of functional nucleic acids. Annu. Rev. Biochem., 68, 611-647.
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 611-647
    • Wilson, D.S.1    Szostak, J.W.2
  • 24
    • 0032476840 scopus 로고    scopus 로고
    • Expanding the potential of DNA for binding and catalysis: Highly functionalized dUTP derivatives that are substrates for thermostable DNA polymerases
    • Sakthivel,K. and Barbas,C.F., III (1998) Expanding the potential of DNA for binding and catalysis: Highly functionalized dUTP derivatives that are substrates for thermostable DNA polymerases. Angew. Chem. Int. Ed., 37, 2872-2875.
    • (1998) Angew. Chem. Int. Ed. , vol.37 , pp. 2872-2875
    • Sakthivel, K.1    Barbas III, C.F.2
  • 26
    • 0035339584 scopus 로고    scopus 로고
    • Enhancing the catalytic repertoire of nucleic acids. II. Simultaneous incorporation of amino and imidazolyl functionalities by two modified triphosphates during PCR
    • Gourlain,T., Sidorov,A., Mignet,N., Thorpe,S.J., Lee,S.E., Grasby,J.A. and Williams,D.M. (2001) Enhancing the catalytic repertoire of nucleic acids. II. Simultaneous incorporation of amino and imidazolyl functionalities by two modified triphosphates during PCR. Nucleic Acids Res., 29, 1898-1905.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 1898-1905
    • Gourlain, T.1    Sidorov, A.2    Mignet, N.3    Thorpe, S.J.4    Lee, S.E.5    Grasby, J.A.6    Williams, D.M.7
  • 27
    • 0035930783 scopus 로고    scopus 로고
    • Expansion of structural and functional diversities of DNA using new 5-substituted deoxyuridine derivatives by PCR with superthermophilic KOD Dash DNA polymerase
    • Sawai,H., Ozaki,A.N., Satoh,F., Ohbayashi,T., Masud,M.M. and Ozaki,H. (2001) Expansion of structural and functional diversities of DNA using new 5-substituted deoxyuridine derivatives by PCR with superthermophilic KOD Dash DNA polymerase. Chem. Commun., 24, 2604-2605.
    • (2001) Chem. Commun. , vol.24 , pp. 2604-2605
    • Sawai, H.1    Ozaki, A.N.2    Satoh, F.3    Ohbayashi, T.4    Masud, M.M.5    Ozaki, H.6
  • 28
    • 0036713391 scopus 로고    scopus 로고
    • Challenging artificial genetic systems: Thymidine analogs with 5-position sulfur functionality
    • Held,H.A. and Benner,S.A. (2002) Challenging artificial genetic systems: thymidine analogs with 5-position sulfur functionality. Nucleic Acids Res., 30, 3857-3869.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 3857-3869
    • Held, H.A.1    Benner, S.A.2
  • 29
    • 0141545111 scopus 로고    scopus 로고
    • Substrate properties of C5-substituted pyrimidine 2′-deoxynucleoside 5′-triphosphates for thermostable DNA polymerases during PCR
    • Kuwahara,M., Takahata,Y., Shoji,A., Ozaki,A.N., Ozaki,H. and Sawai,H. (2003) Substrate properties of C5-substituted pyrimidine 2′-deoxynucleoside 5′-triphosphates for thermostable DNA polymerases during PCR. Bioorg. Med. Chem. Lett., 13, 3735-3738.
    • (2003) Bioorg. Med. Chem. Lett. , vol.13 , pp. 3735-3738
    • Kuwahara, M.1    Takahata, Y.2    Shoji, A.3    Ozaki, A.N.4    Ozaki, H.5    Sawai, H.6
  • 30
    • 0042307464 scopus 로고    scopus 로고
    • Modified DNA bearing 5(methoxycarbonylmethyl)-2′-deoxyuridine: Preparation by PCR with thermophilic DNA polymerase and postsynthetic derivatization
    • Masud,M.M., Ozaki,N.A., Kuwahara,M., Ozaki,H. and Sawai,H. (2003) Modified DNA bearing 5(methoxycarbonylmethyl)-2′-deoxyuridine: preparation by PCR with thermophilic DNA polymerase and postsynthetic derivatization. Chembiochem., 4, 584-588.
    • (2003) Chembiochem. , vol.4 , pp. 584-588
    • Masud, M.M.1    Ozaki, N.A.2    Kuwahara, M.3    Ozaki, H.4    Sawai, H.5
  • 31
    • 1342332935 scopus 로고    scopus 로고
    • 2_p-Deoxycytidines carrying amino and thiol functionality: Synthesis and incorporation by Vent (exo-) polymerase
    • Roychowdhury,A., Illangkoon,H., Hendrickson,C.L. and Benner,S.A. (2004) 2_p-Deoxycytidines carrying amino and thiol functionality: Synthesis and incorporation by Vent (exo-) polymerase. Org. Lett., 6, 489-492.
    • (2004) Org. Lett. , vol.6 , pp. 489-492
    • Roychowdhury, A.1    Illangkoon, H.2    Hendrickson, C.L.3    Benner, S.A.4
  • 33
    • 4544376496 scopus 로고    scopus 로고
    • Generation and enzymatic amplification of high-density functionalized DNA double strands
    • Jäger,S. and Famulok,M. (2004) Generation and enzymatic amplification of high-density functionalized DNA double strands. Angew. Chem. Int. Ed., 43, 3337-3340.
    • (2004) Angew. Chem. Int. Ed. , vol.43 , pp. 3337-3340
    • Jäger, S.1    Famulok, M.2
  • 36
    • 33644759249 scopus 로고    scopus 로고
    • Direct PCR amplification of various modified DNAs having amino acids found in proteins: Convenient preparation of DNA libraries with high-potential activities for in vitro selection
    • Kuwahara,M., Hanawa,K., Ohsawa,K., Kitagata,R., Ozaki,H. and Sawai,H. (2006) Direct PCR amplification of various modified DNAs having amino acids found in proteins: Convenient preparation of DNA libraries with high-potential activities for in vitro selection. Bioorg. Med. Chem., 14, 2518-2526.
    • (2006) Bioorg. Med. Chem. , vol.14 , pp. 2518-2526
    • Kuwahara, M.1    Hanawa, K.2    Ohsawa, K.3    Kitagata, R.4    Ozaki, H.5    Sawai, H.6
  • 37
    • 0029736532 scopus 로고    scopus 로고
    • A rapid method for detecting specific amplified PCR fragments in microtiter plates
    • Ortiz,A. and Ritter,E. (1996) A rapid method for detecting specific amplified PCR fragments in microtiter plates. Nucleic Acids Res., 24, 3280-3281.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 3280-3281
    • Ortiz, A.1    Ritter, E.2
  • 39
    • 0032922298 scopus 로고    scopus 로고
    • Expanding the catalytic repertoire of nucleic acid catalysts: Simultaneous incorporation of two modified deoxyribonucleoside triphosphates bearing ammonium and imidazolyl functionalities
    • Perrin,D.M., Garestier,T. and Hélène,C. (1999) Expanding the catalytic repertoire of nucleic acid catalysts: Simultaneous incorporation of two modified deoxyribonucleoside triphosphates bearing ammonium and imidazolyl functionalities. Nucleosides Nucleotides, 18, 377-391.
    • (1999) Nucleosides Nucleotides , vol.18 , pp. 377-391
    • Perrin, D.M.1    Garestier, T.2    Hélène, C.3
  • 40
    • 0035853643 scopus 로고    scopus 로고
    • Progress towards single-molecule sequencing: Enzymatic synthesis of nucleotide-specifically labeled DNA
    • Augustin,M.A., Ankenbauer,W. and Angerer,B. (2001) Progress towards single-molecule sequencing: Enzymatic synthesis of nucleotide-specifically labeled DNA. J Biotechnol., 86, 289-301.
    • (2001) J Biotechnol. , vol.86 , pp. 289-301
    • Augustin, M.A.1    Ankenbauer, W.2    Angerer, B.3
  • 41
    • 0035813885 scopus 로고    scopus 로고
    • Functionalized DNA: A new replicable biopolymer
    • Thum,O., Jäger,S. and Famulok,M. (2001) Functionalized DNA: A new replicable biopolymer. Angew. Chem. Int. Ed., 40, 3990-3993.
    • (2001) Angew. Chem. Int. Ed. , vol.40 , pp. 3990-3993
    • Thum, O.1    Jäger, S.2    Famulok, M.3
  • 42
    • 0037156350 scopus 로고    scopus 로고
    • Enzymatic synthesis of labeled DNA by PCR using new fluorescent thymidine nucleotide analogue and superthermophilic KOD dash DNA polymerase
    • Ohbayashi,T., Masud,M.M., Ozaki,A.N., Ozaki,H., Kuwahara,M. and Sawai,H. (2002) Enzymatic synthesis of labeled DNA by PCR using new fluorescent thymidine nucleotide analogue and superthermophilic KOD dash DNA polymerase. Bioorg. Med. Chem. Lett., 12, 1167-1170.
    • (2002) Bioorg. Med. Chem. Lett. , vol.12 , pp. 1167-1170
    • Ohbayashi, T.1    Masud, M.M.2    Ozaki, A.N.3    Ozaki, H.4    Kuwahara, M.5    Sawai, H.6
  • 43
    • 0037705457 scopus 로고    scopus 로고
    • Incorporation of reporter molecule-labeled nucleotides by DNA polymerases. I. Chemical synthesis of various reporter group-labeled 2′-deoxyribonucleoside-5′-triphosphates
    • Giller,G., Tasara,T., Angerer,B., Muhlegger,K., Amacker,M. and Winter,H. (2003) Incorporation of reporter molecule-labeled nucleotides by DNA polymerases. I. Chemical synthesis of various reporter group-labeled 2′-deoxyribonucleoside-5′-triphosphates. Nucleic Acids Res., 31, 2630-2635.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 2630-2635
    • Giller, G.1    Tasara, T.2    Angerer, B.3    Muhlegger, K.4    Amacker, M.5    Winter, H.6
  • 44
    • 0037705455 scopus 로고    scopus 로고
    • Incorporation of reporter molecule-labeled nucleotides by DNA polymerases. II. High-density labeling of natural DNA
    • Tasara,T., Angerer,B., Damond,M., Winter,H., Dorhofer,S., Hubscher,U. and Amacker,M. (2003) Incorporation of reporter molecule-labeled nucleotides by DNA polymerases. II. High-density labeling of natural DNA. Nucleic Acids Res., 31, 2636-2646.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 2636-2646
    • Tasara, T.1    Angerer, B.2    Damond, M.3    Winter, H.4    Dorhofer, S.5    Hubscher, U.6    Amacker, M.7
  • 46
    • 0028834955 scopus 로고
    • Gel fidelity assay measuring nucleotide misinsertion, exonucleolytic proofreading, and lesion bypass efficiencies
    • Creighton,S., Bloom,L.B. and Goodman,M.F. (1995) Gel fidelity assay measuring nucleotide misinsertion, exonucleolytic proofreading, and lesion bypass efficiencies. Meth. Enzymol., 262, 232-256.
    • (1995) Meth. Enzymol. , vol.262 , pp. 232-256
    • Creighton, S.1    Bloom, L.B.2    Goodman, M.F.3
  • 47
    • 0033168575 scopus 로고    scopus 로고
    • An in vitro screening technique for DNA polymerases that can incorporate modified polymerases
    • Lutz,S., Burgstaller,P. and Benner,S.A. (1999) An in vitro screening technique for DNA polymerases that can incorporate modified polymerases. Nucleic Acids Res., 27, 2792-2798.
    • (1999) Nucleic Acids Res. , vol.27 , pp. 2792-2798
    • Lutz, S.1    Burgstaller, P.2    Benner, S.A.3
  • 48
    • 8544278025 scopus 로고    scopus 로고
    • DNA polymerase fidelity: Kinetics, structure, and checkpoints
    • Joyce,C.M. and Benkovic,S.J. (2004) DNA polymerase fidelity: Kinetics, structure, and checkpoints. Biochemistry, 43, 14317-14324.
    • (2004) Biochemistry , vol.43 , pp. 14317-14324
    • Joyce, C.M.1    Benkovic, S.J.2
  • 49
    • 7744230597 scopus 로고    scopus 로고
    • Optimization of interstrand hydrophobic packing interactions within unnatural DNA base pairs
    • Matsuda,S. and Romesberg,F.E. (2004) Optimization of interstrand hydrophobic packing interactions within unnatural DNA base pairs. J. Am. Chem. Soc., 126, 14419-14427.
    • (2004) J. Am. Chem. Soc. , vol.126 , pp. 14419-14427
    • Matsuda, S.1    Romesberg, F.E.2
  • 50
    • 33645926663 scopus 로고    scopus 로고
    • Substituent effects on the pairing and polymerase recognition of simple unnatural base pairs
    • Hwang,G.T. and Romesberg,F.E. (2006) Substituent effects on the pairing and polymerase recognition of simple unnatural base pairs. Nucleic Acids Res., 34, 2037-2045.
    • (2006) Nucleic Acids Res. , vol.34 , pp. 2037-2045
    • Hwang, G.T.1    Romesberg, F.E.2
  • 51
    • 33746312883 scopus 로고    scopus 로고
    • Remarkable sensitivity to DNA base shape in the DNA polymerase active site
    • Sintim,H.O. and Kool,E.T. (2006) Remarkable sensitivity to DNA base shape in the DNA polymerase active site. Angew. Chem. Int. Ed., 45, 1974-1979.
    • (2006) Angew. Chem. Int. Ed. , vol.45 , pp. 1974-1979
    • Sintim, H.O.1    Kool, E.T.2
  • 52
    • 31044454139 scopus 로고    scopus 로고
    • DNA polymerase catalysis in the absence of Watson-Crick hydrogen bonds: Analysis by single-turnover kinetics
    • Potapova,O., Chan,C., DeLucia,A.M., Helquist,S.A., Kool,E.T., Grindley,N.D. and Joyce,C.M. (2006) DNA polymerase catalysis in the absence of Watson-Crick hydrogen bonds: Analysis by single-turnover kinetics. Biochemistry, 45, 890-898.
    • (2006) Biochemistry , vol.45 , pp. 890-898
    • Potapova, O.1    Chan, C.2    DeLucia, A.M.3    Helquist, S.A.4    Kool, E.T.5    Grindley, N.D.6    Joyce, C.M.7
  • 53
    • 0029150305 scopus 로고
    • Novel C5-substituted 2′-deoxyuridine derivatives bearing amino-linker arms: Synthesis, incorporation into oligodeoxyribonucleotides, and their hybridization properties
    • Ozaki,H., Nakamura,A., Arai,M., Endo,M. and Sawai,H. (1995) Novel C5-substituted 2′-deoxyuridine derivatives bearing amino-linker arms: synthesis, incorporation into oligodeoxyribonucleotides, and their hybridization properties. Bull. Chem. Soc. Jpn., 68, 1981-1987.
    • (1995) Bull. Chem. Soc. Jpn. , vol.68 , pp. 1981-1987
    • Ozaki, H.1    Nakamura, A.2    Arai, M.3    Endo, M.4    Sawai, H.5
  • 54
    • 0033809004 scopus 로고    scopus 로고
    • A facile one-pot synthesis of 2,3′-anhydro-2′-deoxyuridines via 3′-O-imidazolylsulfonates
    • No,Z., Shin,D.S., Song,B.J., Ahn,M. and Ha,D. (2000) A facile one-pot synthesis of 2,3′-anhydro-2′-deoxyuridines via 3′-O-imidazolylsulfonates. Synth. Commun., 30, 3873-3882.
    • (2000) Synth. Commun. , vol.30 , pp. 3873-3882
    • No, Z.1    Shin, D.S.2    Song, B.J.3    Ahn, M.4    Ha, D.5
  • 55
    • 0030592095 scopus 로고    scopus 로고
    • Structure of Taq polymerase with DNA at the polymerase active site
    • Eom,S.H., Wang,J. and Steitz,T.A. (1996) Structure of Taq polymerase with DNA at the polymerase active site. Nature, 382, 278-281.
    • (1996) Nature , vol.382 , pp. 278-281
    • Eom, S.H.1    Wang, J.2    Steitz, T.A.3
  • 56
    • 0035936690 scopus 로고    scopus 로고
    • Crystal structure of DNA polymerase from hyperthermophilic archaeon Pyrococcus kodakaraensis KOD1
    • Hashimoto,H., Nishioka,M., Fujiwara,S., Takagi,M., Imanaka T. Inoue,T. and Kai,Y. (2001) Crystal structure of DNA polymerase from hyperthermophilic archaeon Pyrococcus kodakaraensis KOD1. J. Mol. Biol., 306, 469-477.
    • (2001) J. Mol. Biol. , vol.306 , pp. 469-477
    • Hashimoto, H.1    Nishioka, M.2    Fujiwara, S.3    Takagi, M.4    Imanaka, T.5    Inoue, T.6    Kai, Y.7
  • 57
    • 27644567193 scopus 로고    scopus 로고
    • Probing the active site tightness of DNA polymerase in subangstrom increments
    • Kim,T.W., Delaney,J.C., Essigmann,J.M. and Kool,E.T. (2005) Probing the active site tightness of DNA polymerase in subangstrom increments. Proc. Natl Acad. Sci. USA, 102, 15803-15808.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 15803-15808
    • Kim, T.W.1    Delaney, J.C.2    Essigmann, J.M.3    Kool, E.T.4
  • 58
    • 33644864228 scopus 로고    scopus 로고
    • Functional evidence for a small and rigid active site in a high fidelity DNA polymerase: Probing T7 DNA polymerase with variably sized base pairs
    • Kim,T.W., Brieba,L.G., Ellenberger,T. and Kool,E.T. (2006) Functional evidence for a small and rigid active site in a high fidelity DNA polymerase: Probing T7 DNA polymerase with variably sized base pairs. J. Biol. Chem., 281, 2289-2295.
    • (2006) J. Biol. Chem. , vol.281 , pp. 2289-2295
    • Kim, T.W.1    Brieba, L.G.2    Ellenberger, T.3    Kool, E.T.4
  • 59
    • 0030727765 scopus 로고    scopus 로고
    • The ups and downs of nucleic acid duplex stability: Structure-stability studies on chemically-modified DNA:RNA duplexes
    • Freier,S.M. and Altmann,K.H. (1997) The ups and downs of nucleic acid duplex stability: Structure-stability studies on chemically-modified DNA:RNA duplexes. Nucleic Acids Res., 25, 4429-4443.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 4429-4443
    • Freier, S.M.1    Altmann, K.H.2
  • 60
    • 0037465559 scopus 로고    scopus 로고
    • Factors that contribute to efficient catalytic activity of a small Ca2-dependent deoxyribozyme in relation to its RNA cleavage function
    • Okumoto,Y., Tanabe,Y. and Sugimoto,N. (2003) Factors that contribute to efficient catalytic activity of a small Ca2-dependent deoxyribozyme in relation to its RNA cleavage function. Biochemistry, 42, 2158-2165.
    • (2003) Biochemistry , vol.42 , pp. 2158-2165
    • Okumoto, Y.1    Tanabe, Y.2    Sugimoto, N.3
  • 61
    • 2342572250 scopus 로고    scopus 로고
    • Probing minor groove recognition contacts by DNA polymerases and reverse transcriptases using 3-deaza-2′-deoxyadenosine
    • Hendrickson,C.L., Devine,K.G. and Benner,S.A. (2004) Probing minor groove recognition contacts by DNA polymerases and reverse transcriptases using 3-deaza-2′-deoxyadenosine. Nucleic Acids Res., 32, 2241-2250.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 2241-2250
    • Hendrickson, C.L.1    Devine, K.G.2    Benner, S.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.