Familial hemiplegic migraine CaV2.1 channel mutation R192Q enhances ATP-gated P2X3 receptor activity of mouse sensory ganglion neurons mediating trigeminal pain

Molecular Pain

Volumn 6, Issue , 2010, Pages

  Nair, Asha ^a,e   Simonetti, Manuela ^a,f   Birsa, Nicol ^a   Ferrari, Michel D ^b   van den Maagdenberg, Arn M J M ^b   Giniatullin, Rashid ^a,c   Nistri, Andrea ^a   Fabbretti, Elsa ^a,d  

^a SISSA   (Italy)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF EASTERN FINLAND   (Finland)

^d UNIVERSITY OF NOVA GORICA   (Slovenia)

^e RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^f UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CHANNEL; CALCIUM CHANNEL CAV2.1; CALCIUM CHANNEL P TYPE; CALCIUM CHANNEL Q TYPE; OMEGA AGATOXIN IVA; PURINERGIC P2X3 RECEPTOR; SERINE; TACROLIMUS; THREONINE; TYROSINE; UNCLASSIFIED DRUG; CACNA1A PROTEIN, MOUSE; CALCINEURIN; MUTANT PROTEIN; OMEGA AGATOXIN I; OMEGA-AGATOXIN I; PHOSPHOSERINE; POTASSIUM; SPIDER VENOM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FAMILIAL HEMIPLEGIC MIGRAINE; GENE MUTATION; MEMBRANE CURRENT; MOUSE; NERVE CELL MEMBRANE STEADY POTENTIAL; NONHUMAN; PATCH CLAMP; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; SENSORY GANGLION; SIGNAL TRANSDUCTION; TRIGEMINUS NEURALGIA; AMINO ACID SUBSTITUTION; ANIMAL; CALCIUM SIGNALING; CELL MEMBRANE POTENTIAL; CHANNEL GATING; DRUG EFFECT; ENZYMOLOGY; GENE TARGETING; GENETICS; INTRACELLULAR SPACE; METABOLISM; MIGRAINE WITH AURA; MUTATION; PAIN; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SENSORY RECEPTOR; TRIGEMINAL NERVE;

ADENOSINE TRIPHOSPHATE; AMINO ACID SUBSTITUTION; ANIMALS; CALCINEURIN; CALCIUM CHANNELS, P-TYPE; CALCIUM CHANNELS, Q-TYPE; CALCIUM SIGNALING; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; ENZYME ACTIVATION; GANGLIA, SENSORY; GENE KNOCK-IN TECHNIQUES; INTRACELLULAR SPACE; ION CHANNEL GATING; MEMBRANE POTENTIALS; MICE; MIGRAINE WITH AURA; MUTANT PROTEINS; MUTATION; PAIN; PHOSPHORYLATION; PHOSPHOSERINE; POTASSIUM; RECEPTORS, PURINERGIC P2X3; SENSORY RECEPTOR CELLS; SPIDER VENOMS; TRIGEMINAL NERVE;

EID: 77955788649     PISSN: 17448069     EISSN: None     Source Type: Journal    
DOI: 10.1186/1744-8069-6-48     Document Type: Article

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