The C-terminal Src inhibitory kinase (Csk)-mediated tyrosine phosphorylation is a novel molecular mechanism to limit P2X3 receptor function in mouse sensory neurons

Journal of Biological Chemistry

Volumn 284, Issue 32, 2009, Pages 21393-21401

  D'Arco, Marianna ^a   Giniatullin, Rashid ^b   Leone, Vanessa ^a,c   Carloni, Paolo ^a,c   Birsa, Nicol ^a   Nair, Asha ^a   Nistri, Andrea ^a   Fabbretti, Elsa ^a,d  

^a ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c DEMOCRITOS NATIONAL SIMULATION CENTER   (Italy)

^d UNIVERSITY OF NOVA GORICA   (Slovenia)

Author keywords

[No Author keywords available]

Indexed keywords

C TERMINUS; CHRONIC PAIN; DOWN-REGULATION; EXTRACELLULAR ATP; EXTRACELLULAR LEVELS; IN-VITRO; INTRACELLULAR SIGNALS; MOLECULAR MECHANISM; NEGATIVE CONTROL; NERVE GROWTH FACTOR; RECEPTOR ACTIVITY; SENSORY NEURONS; STRUCTURAL MODELING; TYROSINE PHOSPHORYLATION;

AMINO ACIDS; NEURONS; PHOSPHORYLATION;

ENZYME ACTIVITY;

ALGOGEN; ENZYME INHIBITOR; NERVE GROWTH FACTOR; PURINERGIC P2X3 RECEPTOR; SRC INHIBITORY KINASE; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR MECHANICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; REGULATORY MECHANISM; SENSORY NERVE CELL; TRIGEMINAL NERVE;

AMINO ACID SEQUENCE; ANIMALS; HUMANS; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE KINASES; RATS; RECEPTORS, PURINERGIC P2; SENSORY RECEPTOR CELLS; SEQUENCE HOMOLOGY, AMINO ACID; TYROSINE;

EID: 69249129036     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.023051     Document Type: Article

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