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European Journal of Medicinal Chemistry

Volumn 45, Issue 9, 2010, Pages 3970-3980

QSAR study of carboxylic acid derivatives as HIV-1 Integrase inhibitors

(3) Cheng, Zhengjun a Zhang, Yuntao a Fu, Weizhong a

a CHINA WEST NORMAL UNIVERSITY (China)

Author keywords

3D MoRSE descriptors; Carboxylic acid derivatives; QSAR; Replacement method; Support vector machine

Indexed keywords

CARBOXYLIC ACID DERIVATIVE; INTEGRASE INHIBITOR; VIRUS ENZYME;

ARTICLE; DRUG ACTIVITY; DRUG DESIGN; DRUG SYNTHESIS; ELECTRON DIFFRACTION; ENZYME INHIBITION; HUMAN IMMUNODEFICIENCY VIRUS 1; MULTIPLE LINEAR REGRESSION ANALYSIS; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; SUPPORT VECTOR MACHINE; VALIDATION PROCESS;

CARBOXYLIC ACIDS; DRUG DESIGN; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; INHIBITORY CONCENTRATION 50; LINEAR MODELS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77955560073 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2010.05.052 Document Type: Article

Times cited : (33)

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