Investigations on the 4-quinolone-3-carboxylic acid motif. 1. Synthesis and structure-activity relationship of a class of human immunodeficiency virus type 1 integrase inhibitors

Journal of Medicinal Chemistry

Volumn 51, Issue 16, 2008, Pages 5125-5129

  Pasquini, Serena ^a   Mugnaini, Claudia ^a   Tintori, Cristina ^a   Botta, Maurizio ^a   Trejos, Alejandro ^b   Arvela, Riina K ^b   Larhed, Mats ^b   Witvrouw, Myriam ^c   Michiels, Martine ^c   Christ, Frauke ^c   Debyser, Zeger ^c   Corelli, Federico ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b UPPSALA UNIVERSITY   (Sweden)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BENZENE; CARBOXYLIC ACID DERIVATIVE; ELVITEGRAVIR; INTEGRASE INHIBITOR;

ARTICLE; CALCULATION; DRUG INHIBITION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; PROTEIN MOTIF; QUANTUM MECHANICS; STRUCTURE ACTIVITY RELATION; VIRUS DNA CELL DNA INTERACTION;

4-QUINOLONES; CELL LINE, TUMOR; CELL SURVIVAL; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; HUMANS; INHIBITORY CONCENTRATION 50; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 50249137113     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm8003784     Document Type: Article

References (12)

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