Novel HIV-1 integrase inhibitors derived from quinolone antibiotics

Journal of Medicinal Chemistry

Volumn 49, Issue 5, 2006, Pages 1506-1508

  Sato, Motohide ^a   Motomura, Takahisa ^a   Aramaki, Hisateru ^a   Matsuda, Takashi ^a   Yamashita, Masaki ^a   Ito, Yoshiharu ^a   Kawakami, Hiroshi ^a   Matsuzaki, Yuji ^a   Watanabe, Wataru ^a   Yamataka, Kazunobu ^a   Ikeda, Satoru ^a   Kodama, Eiichi ^b   Matsuoka, Masao ^b   Shinkai, Hisashi ^a  

^a JT Inc   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; INTEGRASE INHIBITOR; JTK 303; PALLADIUM; QUINOLINE DERIVED ANTIINFECTIVE AGENT; UNCLASSIFIED DRUG;

ALKYLATION; ANTIVIRAL ACTIVITY; ARTICLE; ASSAY; CATALYSIS; CATALYST; DNA STRAND; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG STRUCTURE; ENZYME ACTIVITY; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION ASSAY; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IC 50; NONHUMAN; STRUCTURE ANALYSIS;

ANTI-BACTERIAL AGENTS; CELL LINE; DNA, VIRAL; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; HIV-1; HUMANS; QUINOLONES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33644863638     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0600139     Document Type: Article

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